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Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
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Coarse-Grained Modelling of DNA and DNA Self-Assembly (Paperback, 2012 ed.)
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Coarse-Grained Modelling of DNA and DNA Self-Assembly (Paperback, 2012 ed.)
Series: Springer Theses
Expected to ship within 10 - 15 working days
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This thesis presents a novel coarse-grained model of DNA, in which
bases are represented as rigid nucleotides. The model is shown to
quantitatively reproduce many phenomena, including elastic
properties of the double-stranded state, hairpin formation in
single strands and hybridization of pairs of strands to form
duplexes, the first time such a wide range of properties has been
captured by a coarse-grained model. The scope and potential of the
model is demonstrated by simulating DNA tweezers, an iconic
nanodevice, and a two-footed DNA walker - the first time that
coarse-grained modelling has been applied to dynamic DNA
nanotechnology.
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