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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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Creative Chemical Sensor Systems (Hardcover, 2007 ed.)
Loot Price: R7,679
Discovery Miles 76 790
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Creative Chemical Sensor Systems (Hardcover, 2007 ed.)
Series: Topics in Current Chemistry, 277
Expected to ship within 10 - 15 working days
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Since several excellent books have appeared on the issue of
chemical and biochemical sensing, this compendium concentrates on
recent creative new approaches using chemical means for the
detection and quanti?cation of - portant analytes. These are
presented either from a technical viewpoint or
fromtheperspectiveofselectivemolecularrecognitionwitharti?cialreceptor
molecules. Consequently, the entire book is subdivided into two
categories, i. e. , natural targetsand detection techniques. In the
?rst part, the challenging task of sensing peptides and proteins as
wellassaccharidesisaddressedfromseveralperspectives:Smalllibrarieswith
maximum diversity are ef?ciently used to reach high af?nity and
selectivity of arti?cial hosts for short peptide sequences.
Preorganized aromatic vessels are tailored for certain protein
epitopes and shown to selectively address the prion protein, and a
new conjugation technique operating at physiological conditions on
helix-loop-helix motifs, leads to protein binders of exquisite
af?nity. Finally, elegant sensor systems for multifunctional
carbohydrates in their naturalform,whichuse theprinciple
ofphoto-induced electrontransfer for ?uorescence detection, are
presented. The second part of this book is devoted to creative
detection techniques employing chemical processes: Liposomes with
integral self-assembled - acetylene lipid areas show an intense
blue color, which gradually changes to red if biological analytes
of various sizes speci?cally interact with emb- ded hosts.
Principal component analysis and arti?cial neuronal networks are
novel methods to quantitatively analyze complex mixtures. An
alternative - proach uses arti?cial peptidic pores, which are able
to release self-quenched
?uorophoresthataresubstitutedbytighterbindinganalytes.
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