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Books > Medicine > Other branches of medicine > Pharmacology
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Drug Development - Molecular Targets for GI Diseases (Hardcover, 2000 ed.)
Loot Price: R3,193
Discovery Miles 31 930
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Drug Development - Molecular Targets for GI Diseases (Hardcover, 2000 ed.)
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The application of molecular techniques to gastroenterology
continues to yield important advances in the development of drugs
to treat gastrointestinal disorders. Important new drugs have
emerged through the collaborative and complementary efforts of
basic scientists, clinicians, and clinical researchers in academia
and the pharmaceutical industry. The challenge has been exciting,
with a few surprises along the way. Consider peptic ulcer disease
as an example. The discovery of H receptors and the availability of
potent and 2 selective H-receptor antagonists signaled the
beginning of a new era 2 in the treatment of gastric hypersecretory
states and peptic ulcers. Introduction of proton pump inhibitors
offered another therapeutic option. Though H-receptor antagonists
and proton pump inhibitors 2 are important and useful drugs, the
discovery of the link between H. pylori infection and peptic ulcer
disease has led to even more effective pharmacotherapeutic
regimens. Our intent in Drug Development: Molecular Targets for GI
Diseases is to bring together hands-on experts to review promising
areas of gastrointestinal pharmacology. The contemporary topics
covered, from a mechanistic viewpoint, are relevant to
gastrointestinal inflammation and motility disorders. Authoritative
opinions are offered on both future research directions and
potential applications for new therapies.
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