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D-Amino Acids - Physiology, Metabolism, and Application (Hardcover, 1st ed. 2016)
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D-Amino Acids - Physiology, Metabolism, and Application (Hardcover, 1st ed. 2016)
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This book presents a comprehensive overview of the roles of D-amino
acids and latest research findings, to reveal their fascinating
aspects and to facilitate better understanding of their important
roles in physiology and diseases. It also provides useful hints for
the development of drugs and functional foods. D-Amino acids were
once called unnatural amino acids and were considered to be
insignificant for eukaryotes especially in mammals. However,
different D-amino acids have been revealed to be distributed in
various mammalian tissues and to bear important physiological
roles. For example, D-serine is implicated in memory formation and
learning, and its abnormal concentration in tissues have been
reported in neurological diseases such as schizophrenia and
amyotrophic lateral sclerosis. D-Aspartate is found in a variety of
mammalian tissues, particularly in the central nervous system and
the genitals. D-Aspartate facilitates the endocrine secretion of
prolactin, inhibits the secretion of melatonin, and plays a
peculiar role in the control of reproductive functions in mammals,
including the stimulation of testosterone synthesis. Written by the
leading scientists in the field, this book is a valuable source of
information for researchers in biochemistry, physiology, and
neuroscience, as well as in the pharmaceutical and food industries.
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