Books > Medicine > Clinical & internal medicine > Haematology
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Adult T-cell Leukemia/Lymphoma (Hardcover, 1st ed. 2017)
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Adult T-cell Leukemia/Lymphoma (Hardcover, 1st ed. 2017)
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This book provides essential information on the epidemiology,
molecular and genetic features, anti-CCR4 antibody therapy and a
nationwide study of transplantation on human T-leukemia virus
type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare
but important disease has restricted endemic areas and distinct
clinical features such as a high frequency of hypercalcemia, strong
predisposition to infection and poor response to chemotherapy,
aspects which set ATL apart from other types of non-Hodgkin
lymphoma. Given the small number of patients, enrollment in
clinical trials has not been feasible, and establishing treatment
standard has been difficult but new evidence, such as results of
nationwide studies on transplantation, have shown new insights and
potential treatments. Based on recent evidence, the book presents
new treatment methods for ATL and infection prevention of HTLV-1,
enabling clinicians, researchers and post-docs specializing in
hematology and virology to gain a valuable overview of the disease.
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