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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Tight Junctions in Cancer Metastasis (Hardcover, 2013 ed.)
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Tight Junctions in Cancer Metastasis (Hardcover, 2013 ed.)
Series: Cancer Metastasis - Biology and Treatment, 19
Expected to ship within 12 - 17 working days
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There has been a dramatic increase in knowledge of tight junctions
in the past decade. The molecular structure of tight junctions,
cellular functions and the pathophysiological roles of tight
junctions are becoming clear. Of the most important functions, the
role of the cellular structure in cancer spread and drug delivery
are increasingly realised. It is now clear that there are
fundamental changes to tight junctions during the process of cancer
development. Tight junctions are also critical to the metastatic
process of cancer cells. The cellular structure is also crucial in
drug therapies, namely, the permeability and bioavailability of the
drugs, penetration of barriers such as the blood brain barrier.
This current volume aims to summarise the current knowledge of
tight junctions, their role in cancer and cancer metastasis and is
of interest to scientists and clinicians.
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