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Mathematical Theory of Electrophoresis (Paperback, Softcover Repri)
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Mathematical Theory of Electrophoresis (Paperback, Softcover Repri)
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The development of contemporary molecular biology with its growing
tendency toward in-depth study of the mechanisms of biological
processes, structure, function, and identification of biopolymers
requires application of accurate physicochemical methods.
Electrophoresis occupies a key position among such methods. A wide
range of phenomena fall un der the designation of electrophoresis
in the literature at the present time. One common characteristic of
all such phenomena is transport by an elec tric field of a
substance whose particles take on a net charge as a result of
interaction with the solution. The most important mechanisms for
charge generation are dissociation of the substance into ions in
solution and for mation of electrical double layers with
uncompensated charges on particles of dispersed medium in the
liquid. As applied to the problem of separation, purification, and
analysis of cells, cell organelles, and biopolymers, there is a
broad classification of electrophoretic methods primarily according
to the methodological charac teristics of the process, the types of
supporting media, etc. An extensive literature describes the use of
these methods for the investigation of differ ent systems. A number
of papers are theoretical in nature. Thus, the mi croscopic theory
has been developed rather completely 13] by considering
electrophoresis within the framework of electrokinetic phenomena
based on the concept of the electrical double layer."
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