Camptothecins in Cancer Therapy (Hardcover, 2005 ed.)

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	February 2005
First published:	2005
Editors:	Val R. Adams
Dimensions:	235 x 155 x 31mm (L x W x T)
Format:	Hardcover
Pages:	460
Edition:	2005 ed.
ISBN-13:	978-1-58829-027-4
Categories:	Books > Medicine > Surgery > Surgical oncology Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > Chemotherapy
LSN:	1-58829-027-1
Barcode:	9781588290274

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