Current Topics in Microbiology and Immunology (Paperback, Softcover reprint of the original 1st ed. 1981)

Several discoveries are noteworthy for allowing us to probe the recesses of the virus infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiology or developmental biology. One of the most notable was the dis covery of reverse transcriptase. This marked a momentous occasion in the history of molecular biology. Not only did it provide insight into the mechanism of persistence of retroviruses but it also provided us with an enzyme that could synthesize a DNA copy of any RNA. This DNA copy could then be used as a hybridization reagent to search for both complementary DNA and viral-specific RNA. Thus one could follow the course of any viral infection or probe in tumor cells for hidden viral genomes. Second, a great deal of credit must be given to the geneticists who isolated the various deletion mutants in the 'avian retrovirus system and thus provided us with the frrst means of isolating gene-spe cific probes. Finally, the laboratories which have mapped the genome have provided us with the framework in which to ask very specific questions with our gene-specific probes. Recently, numerous excellent reviews concerning various aspects of the retroviruses have appeared. In this review I shall not even attempt to present a comprehensive review of retroviruses."

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Current Topics in Microbiology and Immunology, 91
Release date:	December 2011
First published:	1982
Authors:	W. Henle • P.H. Hofschneider • P. Koldovsky • H. Koprowski • O Maaloe • F. Melchers • R. Rott • H. G. Schweiger • L. Syru?ek • P.K. Vogt
Dimensions:	244 x 170 x 15mm (L x W x T)
Format:	Paperback
Pages:	278
Edition:	Softcover reprint of the original 1st ed. 1981
ISBN-13:	978-3-642-68060-1
Categories:	Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > Allergies
LSN:	3-642-68060-7
Barcode:	9783642680601

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