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Manual of Biological Markers of Disease - Section B (Loose-leaf)
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Discovery Miles 42 260
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Manual of Biological Markers of Disease - Section B (Loose-leaf)
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This is Section B of the "Manual of Biological Markers of Disease".
It contains information on more than 20 autoantigens related to
important autoimmune connective tissue diseases such as rheumatoid
arthritis, systemic lupus erythematosus, vasculitis and others. For
every autoantigen, there are well annotated sections with detailed
and complete information on detection methods, cellular
localization, biochemical characteristics, function, cDNA and
derived amino acid sequence, gene structure, B and T-cell epitopes
and a list of available monoclonal antibodies. The chapters are all
structured according to an easy-reference fixed template. The text
is greatly enhanced by many schematic figures. After the initial
purchase, the publisher will send the reader a supplement upon
publication, together with an invoice, until such time as they are
notified otherwise. The Manual of Section A and B is an
authoritative compilation of methods for the detection of
autoantibodies (Section A; Fall 1993); the structure, function and
molecular and biochemical concepts of autoantigens (Section B;
Spring 1994); and the clinical importance of measuring
autoantibodies in patients with rheumatic, connective tissue and
autoimmune diseases (Section C; 1994). Contributors include leading
experts in the immunological, molecular biological and clinical
fields. The format of this looseleaf publication allows regular
updating of data as well as inclusion of new advances in research
on autoimmunity. After Section C, Supplements to Sections B and C
will be published with full information on autoantigens implicated
in other autoimmune diseases such as diabetes mellitus and
autoimmune thyroid and liver diseases. It is further intended to
enlarge the scope of the Manual to include additional sections on
other biological markers of arthritis and connective tissue
diseases. This Manual should prove a useful text and reference book
for bench scientists working in the field of autoimmunity, but also
for rheumatologists, general (internal medicine) physicians or
clinical immunologists caring for patients with autoimmune
disorders.
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