Extracellular Matrix Degradation (Hardcover, 2011 Ed.)

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Biology of Extracellular Matrix
Release date:	April 2011
First published:	2011
Editors:	William C. Parks • Robert Mecham
Dimensions:	235 x 155 x 20mm (L x W x T)
Format:	Hardcover
Pages:	255
Edition:	2011 Ed.
ISBN-13:	978-3-642-16860-4
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Promotions
LSN:	3-642-16860-4
Barcode:	9783642168604

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