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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Extracellular Matrix Degradation (Hardcover, 2011 Ed.)
Loot Price: R4,510
Discovery Miles 45 100
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Extracellular Matrix Degradation (Hardcover, 2011 Ed.)
Series: Biology of Extracellular Matrix
Expected to ship within 10 - 15 working days
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Regulated turnover of extracellular matrix (ECM) is an important
component of tissue homeostasis. In recent years, the enzymes that
participate in, and control ECM turnover have been the focus of
research that touches on development, tissue remodeling,
inflammation and disease. This volume in the Biology of
Extracellular Matrix series provides a review of the known classes
of proteases that degrade ECM both outside and inside the cell. The
specific EMC proteases that are discussed include cathepsins,
bacterial collagenases, matrix metalloproteinases, meprins, serine
proteases, and elastases. The volume also discusses the domains
responsible for specific biochemical characteristics of the
proteases and the physical interactions that occur when the
protease interacts with substrate. The topics covered in this
volume provide an important context for understanding the role that
matrix-degrading proteases play in normal tissue remodeling and in
diseases such as cancer and lung disease. The series Biology of
Extracellular Matrix is published in collaboration with the
American Society for Matrix Biology.
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