The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep - mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science - why we sleep and why we cannot survive without it.

This issue of Sleep Medicine Clinics focuses on Sleep Disorders in Women's Health, with topics including: Menstrual cycle effects on sleep; Impact of shiftwork on sleep, circadian rhythyms, and health in women; Sleep in pregnancy; RLS in pregnancy; Sleep-disordered breathing in pregnancy; Postpartum sleep and circadian rhythms; Chronic pain and autoimmune disorders in women; Management of sleep disturbance in women with cancer; Impact of stress and trauma on sleep; Sleep disorders in female veterans; Sleep and sleep disorders in the menopausal transition; and Impact of sleep disturbance on health and cognition in elderly women.

The Auditory System in Sleep, Second Edition presents a view of a sensory system working in a different state, that of the sleeping brain. This updated edition contains new chapters on topics such as implanted deaf patients and sleep and tinnitus treatments. It is written for basic auditory system and sleep researchers, as well as practitioners and clinicians in the Auditory/Sensory Neurosciences and Sleep Medicine. As the auditory system is always "open", thus receiving information from the environment and the body itself (conscious and unconscious data), the incoming sensory information may alter sleep and waking physiology, and conversely, the sleeping brain. This book draws information from evoked potentials, fMRI, PET, SPECT, lesions, and more.

This issue of Sleep Medicine Clinics focuses on Sleep in Older Adults, with topics including: Sleep in Normal Aging; Insomnia in the Older Adult; Sleep Apnea in the Older Adult; Circadian Rhythm Sleep-Wake Disorders in the Older Adult; Restless Legs Syndrome; Periodic Limb Movement Disorder and Other Sleep Related Movement Disorders in the Older Adult; REM Sleep Behavior Disorder and Other Parasomnias in the Older Adult; Neurodegenerative Disorders and Sleep; Medical Conditions and Sleep in the Older Adult; Psychiatric Illness and Sleep in the Older Adult; Sleep and Cognition in the Older Adult; Sleep and Nocturia in the Older Adult; Sleep and Long Term Care; and Sleep in the Hospitalized Older Adult.

This issue of Sleep Medicine Clinics is edited by Drs. Brown and Shahrokh Javaheri and focuses on Advanced PAP Therapies and Non-invasive Ventilation. Article topics include: Current Positive Airway Pressure Device Technology: What's in the "black box?"; Testing the Performance of Positive Airway Pressure Generators: From Bench to Bedside; Treatment of Obstructive Sleep Apnea: Choosing the Best PAP Device; Treatment of Obstructive Sleep Apnea: Choosing the Best Interface; Treatment of Obstructive Sleep Apnea: Achieving Adherence and Dealing with Complications; Treatment of Hyperventilatory Central Sleep Apnea: Idiopathic, CHF, Cerebrovascular Disease, and High Altitude; Disordered Breathing Due to Chronic Opioid Use: Diverse Manifestations and Their Management; Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment for a Heterogeneous Disorder; Positive Airway Pressure Treatment in the Patient with Ventilatory Failure due to Neuromuscular Disease; Non-invasive Ventilation in Acute Ventilatory Failure; Domiciliary Non-invasive Ventilation for Chronic Ventilatory Failure; The Future of Positive Airway Pressure Technology.

This issue of Sleep Medicine Clinics is edited by Dr.Ahmed BaHammam and focuses on Hypersomnia. Article topics include: Hypersomnia: neurobiological basis; Narcolepsy Immunogenetics: Where is the Evidence?; Genetic markers of sleepiness; Autonomic function instabilities in Narcolepsy; Epidemiology of Excessive Daytime Sleepiness; Evaluation of the sleepy patient: differential diagnosis; Subjective and objective assessment of hypersomnia; Sleepiness in Narcolepsy; Idiopathic hypersomnia; Sleep disordered breathing and excessive daytime sleepiness; Drug-induced excessive sleepiness; Kleine-Levin syndrome and recurrent hypersomnia; Behaviorally induced insufficient sleep syndrome: an underestimated cause of hypersomnia; Sleepiness in children; Sleepiness in Adolescents; Sleepiness in the elderly; Depression and Hypersomnia: a complex association; Neurodegenerative diseases and excessive sleepiness; Sleepiness and traffic safety; Pharmacological management of excessive daytime sleepiness; Non-pharmacological management of excessive daytime sleepiness.

This issue of Otolaryngologic Clinics of North America, devoted to Obstructive Sleep Apnea, is guest edited by Dr. Mark A. D'Agostino. Articles in this outstanding issue include: Pediatric Sleep Apnea; Skeletal Procedures for Obstructive Sleep Apnea; Nasal Obstruction and its Role in Obstructive Sleep Apnea and Nasal procedures; Sleep Testing; Drug-induced Sleep Endoscopy; PAP Therapy for Obstructive Sleep Apnea; Palatal Procedures for Obstructive Sleep Apnea; Oral Appliances for Obstructive Sleep Apnea; Obstructive Sleep Apnea Overview and Economic Impact of Untreated Obstructive Sleep Apnea; Genioglossal Advancement, Hyoid Suspension and Tongue Base Radio Frequency for Obstructive Sleep Apnea, Endoscopic Partial Midline Glossectomy; Robotic Partial Glossectomy for Obstructive Sleep Apnea; Upper Airway Stimulation Therapy.

This issue of Sleep Medicine Clinics focuses on Ambulatory Sleep Medicine. Article topics include: Diagnosis of Obstructive Sleep Apnea; Personalised medicine for Obstructive Sleep Apnea therapies: Are we there yet?, Cardiovascular risk of Obstructive Sleep Apnea; Motor Vehicle Accident risk related to Obstructive Sleep Apnea; Impact of Obstructive Sleep Apnea Syndrome on Neurocognitive function and impact of CPAP; CPAP therapy for Obstructive Sleep Apnea; Maximizing adherence including using novel IT based systems; Mandibular advancement splints; Surgical approaches to Obstructive Sleep Apnea; Consequences of Obstructive Sleep Apnea; and more!

Dr. Flavia B. Consens has assembled an expert team of authors on the topic of Sleep in Medical and Neurologic Disorders. Articles include: Sleep and pulmonary disease, Sleep and Pain, Sleep and Neurodegenerative Disorders, Sleep and Stroke, Sleep in the pediatric population, Sleep and cancer, Narcolepsy and excessive daytime sleepiness, Sleep in the hospitalized patient, Sleep and psychiatric disorders, Occupational sleep medicine, and more!

The strong association between mental health and sleep is examined here in topics that include: Epidemiology of sleep disorders, co-morbidity with mental health disorders and impact on health and quality of life; Neurobiology of sleep; Neurobiology of circadian rhythms; Genetics of sleep disorders; Sleep disturbances in anxiety disorders; Sleep disturbances in mood disorders; Sleep disturbances in schizophrenia; Sleep disturbances in substance abuse disorders; Sleep disturbances and behavioral disturbances in children and adolescents; Sleep disturbances and behavioral disturbances in the elderly; Sleep disturbances and behavioral symptoms in medical patients; Effects of psychotropic medications on sleep continuity and sleep architecture; Circadian rhythm sleep disorders; New developments in sleep medications of relevance to mental health disorders; and Primary sleep disorders: identification and treatment by psychiatrists.

Dr. Phyllis Zee has put together an expert panel of authors on the topic of the Science of Circadian Rhythms. Articles include: Neurobiology of Circadian Rhythm Regulation, Effect of Light and Melatonin and other Melatonin Receptor Agonists on Human Circadian Physiology, Consequences of Circadian Disruption on Cardiometabolic Health, Consequences Circadian Disruption on Neurologic and Psychiatric Health, Aging and Circadian Rhythms, Circadian and Homeostatic Regulation of Sleep and Performance, Circadian disruption in Psychiatric Disorders, and more!

Dr. Denise Sharon has put together an expert panel of authors on the topic of Restless Legs Syndrome and Movement Disorders. The comprehensive list of articles includes: Restless Legs Syndrome across the Globe, Neuroimaging in Restless Legs Syndrome, What's in the family of the RLS/WED patient?, Clinical Diagnosis and Diagnostic Criteria, Non-pharmacological management: myths vs. science, Sleep Bruxism, Leg Cramps, Hypnic Jerks, and more!

Drs. John Herman and Max Hirshkowitz have assembled an expert panel of authors in the topic of Sleep and Psychiatry in Adults. Articles include: Sleep Deprivation and Circadian Disruption; Sleep Disturbances in Depression; Interventions for Sleep Disturbance in Bipolar Disorder; Sleep and Mood During Pregnancy and the Postpartum Period,Sleep Disturbances and Suicide Risk; Insomnia and Anxiety, Interconnectedness of Psychological Suymptoms, Personality Traits, and Sleep Disruption; Sleep in Schizophrenia; Post-traumatic Stress Disorder and Sleep; Benzodiazepine and Benzodiazepine Receptor Agonists for Insomnia and Anxiety; Non-benzodiazpine GABA A1 Receptor Agonists for Insonmia; CBT for Insomnia and Depression; Hypnosis for Insomnia in Patients with Depression and Anxiety; and Bright Light Therapy for Seasonal Affective Disorders.

This issue, edited by Dr. Babak Mokhlesi, features comprehensive discussion on the subject of Hypoventilation. Articles include: The History of Hypoventilation Syndromes; Pathophysiology of Hypoventilation During Sleep, Sleep Hypoventilation: Diagnostic Considerations and Technological Limitations; Advances in Positive Airway Pressure Treatment Modalities for Hypoventilation Syndromes; Scoring Abnormal Respiratory Events on Polysomnography During Noninvasive Ventilation; Obesity Hypoventilation Syndrome: Epidemiology and Diagnosis; Outcomes for Obese Patients with Chronic Respiratory Failure: Results from Observational and Randomized Controlled Trials; Non-PAP Treatment Modalities in Obesity-Hypoventilation Syndrome: Role of Exercise, Nonsurgical and Surgical Weight Reduction, Tracheostomy, Respiratory Stimulants, and Oxygen, and more!

This issue by Dr. Judith Owens focuses on sleep behavioral problems with articles covering topics such as Addressing Sleep Problems in Children with Anxiety Disorders, Behavioral Treatment of Insomnia in Children with Attention Deficit Hyperactivity Disorder (ADHD), Application of Cognitive Behavioral Therapy for Insomnia (CBT) in the Pediatric Population, Treatment of Delayed Sleep Phase Disorder (DSPD) in Adolescents, Tricks of the Trade: Practical Techniques for Managing Behavioral Sleep Problems in Young Children ,Quality of Life in Children with Narcolepsy, Myofunctional Therapy in the Treatment of Pediatric Sleep Disordered Breathing, Improving Positive Airway Pressure (PAP) Adherence in Children, Creating the "Child-Friendly" Sleep Lab, Controversies in Treatment of Pediatric Insomnia.

Principles and Practice of Pediatric Sleep Medicine,2nd Edition, written by preeminent sleep medicine experts Drs. Sheldon, Ferber, Kryger, and Gozal, is the most comprehensive source for diagnosing and managing sleep disorders in children. Newly updated and now in full color throughout, this medical reference book is internationally recognized as the definitive resource for any health practitioner who treats children, providing absolute guidance on virtually all of the sleep-associated problems encountered in pediatric patients. "..a well-written, comprehensive, and succinct textbook." Reviewed by Sanjeev V Kothare on behalf of Journal of Clinical Neurophysiology, February 2015 Organized format separates coverage into Normal and Abnormal sleep for quick access to the key information you need. Abundantly referenced chapters help you to investigate topics further. Equips you with a complete understanding of both medical and psychiatric sleep disorders. New and expanded chapters regarding sleep related breathing disorders; parasomnias; differential diagnosis of pediatric sleep disorders; hypersomnia; school start times and implications; and the evaluation and management of circadian rhythm disturbances. Extensive coverage on obstructive sleep apnea, diagnosis and treatment; evaluation and management of sleepy children; evaluation and management of circadian rhythm abnormalities; and pharmacology. Online access via Expert Consult for seamlessly searchable contents.

Dr. Peter Gay has put together a team of expert authors centering on the topic of Central Sleep Apnea. Focus will include articles on CSA due to other Medical Disorders, Cheyne-Stokes Respiration, Central Sleep Apnea and Cardiovascular Disease, Complex Sleep Apnea, Adaptive servo-ventilation Treatment, Drug induced central apneas- Mechanism and Therapies, ICSD-2 and AASM Practice Parameters, Alternative approaches to treatment of Central Sleep Apnea, and Infant central apnea

This issue of Sleep Medicine Clinics will be Guest Edited by Jim Barker, MD CPE, FACP, FCCP, FAASM Shirley Fong Jones, MD, FCCP of Scott and White Memorial Hospital and will focus on Obstructive Sleep Apnea. Article topics include Weight loss, Pharmacologic therapy of obstructive sleep apnea, Alternative Therapies, Masks and Interfaces, Outcomes of treatment of hypersomnia for OSA, Effects of therapy on CV outcomes, Complex Sleep Apnea, Oral appliances, Cost of therapy, Medicolegal aspects of treatment, Residual sleepiness, Therapy and Metabolic Outcomes, and Therapies for Children with OSA.

Effectively diagnose and manage adult and pediatric sleep disorders with help from Atlas of Sleep Medicine, the most comprehensive and detailed source of pictorial and video guidance available. A full-color design with an entirely new image collection and video segments facilitates the observation and interpretation of sleep-related events and recordings. Whether you are preparing for the sleep medicine fellowship examination, or simply want to offer your patients today's best care, this sleep medicine book is an ideal resource! Confidently treat sleep-related breathing disorders with a practical step-by-step approach to positive pressure titration, summarizing merits, demerits, dangers, and limitations. Observe, evaluate, and treat unusual, uncommon, and often unrecognized PSG patterns. See how clinical and PSG findings correlate in real time for various sleep disorders by watching video segments (new to this edition!) that show sleep movements and polysomnography data side by side. Visually reinforce your understanding of circadian dysrhythmias through dynamic hypnograms and a tantalizing pictorial display. Evaluate indications and choose appropriate dental appliances with step-by-step instruction and supporting video clips. Address undesired phenomena that occur in association with sleep with eight new unique vignettes with associated videos including a variety of parasomnias, cataplexy, and death from obstructive sleep apnea. Access the fully searchable text online including the complete image library, over two dozen videos, and more at Expert Consult. With 61 contributors

Yoga therapy offers a truly holistic approach to solving the growing problem of insomnia. In this book expert yoga therapist Lisa Sanfilippo explains how yoga practices can be used to target the underlying issues that inhibit good quality sleep, with immediate results that build over time. Learn how to work with clients to release tension in the body that builds up during the day making it difficult to sleep at night. Honouring a natural yogic and Ayurvedic approach, and infusing it with modern neuroscience, Lisa also addresses the deeper emotional reasons for not sleeping well and looks at how lifestyle changes can help to achieve better quality rest. With the body-mind connection at its core, this book shows how to support better health holistically to restore balance in each layer of the body.

This issue of Sleep Medicine Clinics, Guest Edited by Richard Castriotta, MD of the University of Texas, will focus on Sleep and Neurorehabilitation. Article topics will include TBI and Sleep, Circadian Rhythm Disorders, Insomnia, and Stroke and Sleep.

Sleep disorders are a widely recognized consequence of many neurological pathologies. This issue of Neurologic Clinics features the following articles: Sleep Physiology; Sleep Assessment Tools for the Neurologist; Fitting Sleep into Neurological Practice;? Insomnia; Parasomnias and look-alikes; Sleep Apnea: Obstructive and central; Restless Legs syndrome; Circadian Rhythm; Pediatric Sleep Disorders; Dementia;? Stroke; Epilepsy; CNS Immunological and Infectious; Movement Disorders; Neuromuscular; Headache; Traumatic Brain Injury; and? Psychiatry in Sleep.

This issue of Sleep Medicine Clinics, Guest Edited by Teofilo Lee-Chiong MD, will focus on Biology of Sleep, with article topics including: Neurology of Sleep; Normal Sleep and Circadian Rhythms: Neurobiologic Mechanisms Underlying Sleep and Wakefulness; Physiology of Sleep Disordered Breathing; Evaluation of the Patient Who Has Sleep Complaints: A Case-Based Method Using the Sleep Process Matrix; Sleep States, Memory Processing, and Dreams; Neurobiologic Mechanisms in Chronic Insomnia; Sleep Behavior and Sleep Regulation from Infancy through Adolescence: Normative Aspects; Biological Timekeeping; Neurologic Basis of Sleep Breathing Disorders; Genetics of Sleep Timing, Duration, and Homeostasis in Humans; Sleep in Normal Aging; Modulation of Endocrine Function by Sleep-Wake Homeostasis and Circadian Rhythmicity; Cardiac Activity and Sympathovagal Balance During Sleep; Sleep and Cytokines; Neuropharmacology of Sleep and Wakefulness; Staging Sleep; Respiratory Physiology During Sleep; and Cyclic Alternating Pattern (CAP), Sleep Disordered Breathing, and Automatic Analysis

Portable Sleep monitoring is a very important method of diagnosis and follow-up for sleep-disordered breathing.? This state-of-the-art issue reviews the most recent information on classification, technical specifications and types of portable monitors, use and limitations of portable monitoring with integration into positive airway pressure treatment. use of portable monitors in children and in patients with oral appliances.? Use of portable monitoring for SDB treatment with upper airway surgery is also discussed.? Current published standards incliding CMS requirements for portable monitoring are reviewed.? Outcome measures, illustrative cases, and a comparison with polysomnogram are included.? Finally, future directions are discussed.

This issue on Sleep Electroencephalography (EEG) gives an overview of Electrophysiological readings in sleep with such articles as "The Nuts and Bolts of EEG? and "How the Sleep/Wake EEG Changes Across the Lifespan.? Identifying abnormal EEG activity and patterns in the Electroencephalographic readings is also discussed.? The issue then further focuses in on Seizures and the EEG; specifically, how EEG can be used to diagnosis and identify seizure disorders and differentiate seizures from other paroxysmal nocturnal events, and to diagnose other primary sleep disorders in people with epilepsy.