Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity...), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bin Lu MIPs for binding macromolecules, by Kenneth J. Shea Solid phase extraction, by Ecevit Yilmaz Sensors, by Sergey A. Piletsky MIPs for catalysis and synthesis, by Marina Resmini Wastewater treatment, by Bo Mattiasson MIPs as tools for bioassays, biotransformation and drug delivery, by Meiping Zhao

What should the average person know about science? Because science is so central to life in the 21st century, science educators and other leaders of the scientific community believe that it is essential that everyone understand the basic concepts of the most vital and far-reaching disciplines. Biotechnology 101 does exactly that. This accessible volume provides readers - whether students new to the field or just interested members of the lay public - with the essential ideas of biotechnology using a minimum of jargon and mathematics. Concepts are introduced in a progressive order so that more complicated ideas build on simpler ones, and each is discussed in small, bite-sized segments so that they can be more easily understood. Biotechnology 101 provides an introduction to all the areas of biotechnology, covering such topics as: BLA History of the Science Behind Biotechnology BLThe Tools of Biotechnology BLBiotechnology Innovations BLPrincipal people of Biotechnology BLBiotechnology in Everyday Life BLEthical Issues of Biotechnology This short volume will enable students and lay people to understand the basics of one of the most important scientific fields of endeavor for the future.

Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.

After the 1986 and 1989 volumes, this is the third volume on biotechnology for propagation of trees. Comprising 28 chapters contributed by international experts the book deals with fruit, ornamental, and forest trees, such as Black cherry, Sour cherry, Pomegranate, Loquat, "Ficus," Yellow poplar, Horse chestnut, Judas tree, Linden tree, Saskatoons, Taiwan sassafras, Plane-tree, Rattans, Bamboos, Engelmann spruce, White spruce, Larches, Hinoki cypress, Western redcedar, and various types of pines, i.e. Jack, Carribean, Eldarica, Slash, Egg-cone, Maritime, Ponderosa, Eastern white, Loblolly pine. Trees III is an excellent reference book for scientists, educators, and students of forestry, botany, genetics, and horticulture, who are interested in tree biotechnology.

The book provides a fascinating overview about current and sophisticated developments in applied entomology that are powered by molecular biology and that can be summarized under a novel term: insect biotechnology. By analogy with the application of powerful molecular biological tools in medicine (red biotechnology), plant protection (green biotechnology) and industrial processing (white biotechnology), insect biotechnology (yellow biotechnology) provides novel tools and strategies for human welfare and nutrition. Insect Biotechnology has emerged as a prospering discipline with considerable economic potential, and encompasses the use of insect model organisms and insect-derived molecules in medical research as well as in modern plant protection measures.

Biosensors have captured the imagination of the world's scientific and commercial communities by combining interdisciplinary skills of biologists, physicists, chemists and engineers to provide innovative solutions to analytical problems. Biosensors are applicable to clinical diagnostics, food analysis, cell culture monitoring, environmental control and various military situations. Ever increasing demands for rapid and convenient analyses of a wide variety of materials in diverse locations has led to intense interest in the fusion of biology and electronics which mimics our principal concern: the effect of materials and environments on living systems. This series, "Advances in Biosensors", presents a compendium of research papers, in which authorities in the field of biosensors provide an up-to-date overview of their laboratory's contribution, summarizing the primary research as it has appeared, possibly scattered, in the journal and conference literature, and reflecting on their findings. The net result will be intense, yet highly readable accounts of the state of the art at this leading edge of analytical technology.

Additive manufacturing (AM) and subtractive manufacturing (SM) offer numerous advantages in the production of single and multiple components. They provide incomparable design independence and are used to fabricate products in several industries, e.g.: aeronautic, automotive, biomedical, etc. The book presents recent results of processes including 3D printing, SLS (selective laser sintering), EBM (electron beam melting) and Precise Cutting and Drilling.

PART I - APPARATUS AND PRINCIPLES USED IN MICRODIFFUSION ANALYSIS - II. A STANDARD MICRO DIFFUSION APPARATUS OR 'UNIT' - III. FACTORS INFLUENCING THE ABSORPTION RATE FROM OUTER TO INNER CHAMBER WITH SPECIAL REFERENCE TO AMMONIA - IV. GENERAL PRINCIPLES GOVERNING THE ABSORPTION TIME IN MICRO DIFFUSION ANALYSIS - V. PIPETTES (SUITABLE FOR USE WITH THE STANDARD UNITS) AND THEIR DELIVERY ERRORS - VI. MICRO-BURETTES (SUITABLE FOR USE WITH THE STANDARD UNITS) AND ERRORS INVOLVED IN THEIR USE - VII. THE MICRODIFFUSION METHOD WITH END-POINT VOLUMES AROUND 20 CUBIC MILLIMETRES - VII. COLORIMETRY IN THE MICRODIFFUSION METHODS - PART II - DESCRIPTION OF METHODS WITH THE STANDARD UNITS - IX. AMMONIA. GENERAL METHOD USING STANDARD ACID AS ABSORBENT - X. AMMONIA. GENERAL METHOD (USING THE BORIC-HCL PROCEDURE) - XI. SPECIAL FACTORS INFLUENCING THE RATE OF AMMONIA ABSORPTION - XII. OTHER METHODS FOR DETERMINING THE ABSORBED AMMONIA IN THE MICRO DIFFUSION PROCEDURE - XIII. AMMONIA. BIOLOGICAL DETERMINATIONS - XIV. TOTAL NITROGEN XVII. UREA (BLOOD AND URINE) - XIX. ADENOSINETRIPHOSPHORIC ACID, ADENYLIC ACID, ADENOSINE, ETC. - XX. NITRATE, NITRITE AND AMIDE NITROGEN - XXII. MONOAMINE OXIDASE AND HISTAMINASE IN TISSUES - XXIII. DETERMINATION OF VOLATILE AMINES - XXIV. CARBONATES AND BICARBONATE - XXV. BLOOD GLUCOSE AND FERMENTABLE SUGAR IN NORMAL URINE - XXVI. DETERMINATION OF CARBONIC ANHYDRASE - XXVII. OXIDATION RATES OF ORGANIC SUBSTANCES WITH A STANDARD OXIDANT WITH APPLICATION TO DETERMINATION OF MINUTE AMOUNTS OF CALCIUM AS OXALATE - XXVIII. ACETIC ACID AND OTHER LOWER FATTY ACIDS - XXIX. ASSAY OF ACETYLCHOLINESTERASE - XXX. CYANIDE, AZIDE, SULPHIDE, PHENOLS - XXXI. METHANOL AND ISOPROPANOL GROUP - XXXII. ETHANOL - XXXIII. ETHANOL FROM URETHANE - XXXIV. FORMALDEHYDE - XXXV. FORMALDEHYDOGENIC STEROIDS (PERIODIC ACID AS OXIDANT) - XXXVI. FORMALDEHYDOGENIC STEROIDS (SODIUM BISMUTHATE AS OXIDANT) - XXXVII. GLYCINE (FORMALDEHYDE PRODUCED BY NINHYDRIN OXIDATION) - XXXVIII. ACETALDEHYDE (SEMICARBAZIDE ABSORPTION) - XXXIX. ACETALDEHYDE FROM LACTIC ACID AND THREONINE WITH BISULPHITE ABSORPTION - XL. ACETONE (INCLUDING A RAPID CLINICAL METHOD USING THE NESSLER SOLUTION) - XLI. THE HALOGENS (INTRODUCTORY) - XLII. CHLORIDE (BY OXIDATION TO CHLORINE AND ABSORPTION INTO IODIDE) - XLIII. CHLORIDE (BY OXIDATION TO CHLORINE AND ABSORPTION INTO FAST GREEN) - XLIV. BROMIDE - XLV. IODIDES AND HALOGEN MIXTURES - XLVI. SERIAL DETERMINATION OF ORGANICALLY BOUND HALOGEN - XLVII. VOLATILE HALOGENATED HYDROCARBONS (CHLOROFORM, TRICHLORETHYLENE AND CARBON TETRACHLORIDE) - XLVIII. CARBON MONOXIDE - XLIX. A RAPID CLINICAL METHOD FOR CARBON MONOXIDE DETERMINATION - LI. TOTAL MOLECULAR CONCENTRATION IN FLUID SAMPLES OF ABOUT 3-4 MILLIGRAMS - LII. SEPARATION OF CRYSTALS AND' GUMS' BY MICRODIFFUSION - QUALITATIVE MICRO-DIFFUSION ANALYSIS - LIII. SOME CONSIDERATIONS ON QUALITATIVE MICRO-DIFFUSION ANALYSIS - PART III - THE ERROR OF VOLUMETRIC TITRATION - LIV. INTRODUCTORY - LV. THE VARIABLE GLASS ERROR - LVI. THE TOTAL VARIABLE GLASS ERROR AND ITS CONTROL - LVII. THE VARIABLE CHEMICAL ERROR IN TITRATION - LVIII. THE RATIONALE OF MICRO TITRATION - LIX. THE CONSTANT GLASS ERROR - LX. THE CONSTANT CHEMICAL ERROR - LXI. VOLUMETRIC ERROR IN KJELDAHL NITROGEN ANALYSES - LXIII. UREA EXCRETION AS RENAL FUNCTION TEST - Full TOC available on website

Age as Disease explores the foundations of gerontology as a discipline to examine the ways contemporary society constructs old age as a disease-state. Framed throughout as 'gerontological hygeine', this book examines contemporary regimes, strategies and treatment protocols deployed throughout Australia, the United States, and the United Kingdom. The book deploys critical cultural theories such as biopolitics, somatechnics, ethics, and governmentality to examine how anti-aging technologies operate to problematise the aging body as always-already diseased, and how these come to constitute a movement of abolition, named here as 'gerontological hygiene'.

The book provides background knowledge on the molecular biology of plants and a comprehensive description of plant biotechnology. It is in three parts. Part A deals with an overview of Plant Molecular Biology. Part B is concerned with Plant Tissue Culture. Part C is about Plant Genetic Engineering and Biotechnological Applications. Several transgenic applications dealt with in detail are in areas of engineering plants for stress tolerance, metabolic engineering of plants, transplastomic technology, crop protection, and antisense technology in plants. One of the highlights of this book is that it presents the concepts of both plant molecular biology and plant biotechnology.

Many industrial, power generation and chemical processes produce unwanted fine particulate material as a consequence of their operation. Electrostatic precipitation is a highly efficient method of removing entrained particulate contaminants from exhaust gases and is extensively used in these industries to limit particulate emissions. New legislation aimed at improving the environment by further limiting these discharges has resulted in the technique undergoing considerable development over the past decade, to the point where it has become the method of choice, over a wide range of applications, for limiting particulate discharges. In this new book, the editor has brought together an international team of contributors, mainly industrialists and consultants, to produce an authorative and practical guide to electrostatic precipitation. This book is of interest to all those in process industries or power generation and to academics concerned with gas cleaning and environmental issues.

"Animal Cell Biotechnology: Methods and Protocols, Third Edition" constitutes a comprehensive manual of state-of-the-art and new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture from lab to final production. The volume is divided into five parts that reflect the processes required for different stages of production. In Part I, basic techniques for establishment of production cell lines are addressed, especially high-throughput synchronization, insect cell lines, transient gene and protein expression, DNA Profiling and Characterisation. Part II addresses tools for process and medium optimization as well as microcarrier technology while Part III covers monitoring of cell growth, viability and apoptosis, metabolic flux estimation, quenching methods as well as NMR-based techniques. Part IV details cultivation techniques, and Part V describes special applications, including vaccine production, baculovirus protein expression, chromatographic techniques for downstream as well as membrane techniques for virus separation. Written in the successful "Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

"Animal Cell Biotechnology: Methods and Protocols, Third Edition" provides a compendium of techniques for scientists in industrial and research laboratories that use mammalian cells for biotechnology purposes.

The medical device and drug industries standards in analytical methodology and are consistently among the strongest techno- quality control. logical performers. Materials are a key The users of Biomaterials Engineering ingredient in their dynamic growth. Devel- and Devices: Human Applications will r- opment of these materials is in a constant resent a broad base of backgrounds ranging state of activity, with the challenge of re- from the basic sciences (e. g. , polymer placing old materials that cannot withstand chemistry and biochemistry) to more the tests of time, and the new materials' applied disciplines (e. g. , mechanical/ needs coming to the forefront in modern chemical engineering, orthopedics, and applications. This new reference text, pharmaceutics). To meet varied needs, each Biomaterials Engineering and Devices: chapter provides clear ancd fully detailed Human Applications, focuses on materials discussions. This in-depth, but practical, used in or on the human body-materials coverage should also assist recent indu- that define the world of "biomaterials. " ees to the biomaterials circle. The editors Biomaterials Engineering and Devices: trust that this reference textbook conveys Human Applications focuses on mate- the intensity of this fast moving field in an rials development and characterization. enthusastic presentation. Chapters deal with issues in the selection of Donald L. Wise, PHD proper biomaterials from biocompatibility Debra J. Trantolo, PHD to biostability to structure/function relation- Kai-Uwe Lewandrowski, MD ships. Chapters also focus on the use of Joseph D. Gresser, PHD specific biomaterials based on their physio- Mario V.

This book illustrates the major trends in applied microbiology research with immediate or potential industrial applications. The papers proposed reflect the diversity of the application fields. New microbial developments have been done as well in the food and health sectors than in the environmental technology or in the fine chemical production. All the microbial genera are involved : yeast, fungi and bacteria. The development of biotechnology in parallel with the industrial microbiology has enabled the application of microbial diversity to our socio-economical world. The remarkable properties of microbes, inherent in their genetic and enzymatic material, allow a wide range of applications that can improve our every day life. Recent studies for elucidating the molecular basis of the physiological processes in micro-organisms are essential to improve and to control the metabolic pathways to overproduce metabolites or enzymes of industrial interest. The genetic engineering is of course one of the disciplines offering new horizons for the " fantastic microbial factory " . Studies of the culture parameter incidence on the physiology and the morphology are essential to control the response of the micro-organisms before its successful exploitation at the industrial scale. For this purpose, fundamental viewpoints are necessary. Development of novel approaches to characterise micro-organisms would also facilitate the understanding of the inherent metabolic diversity of the microbial world, in terms of adaptation to a wide range of biotopes and establishment of microbial consortia.

Rotary reactors or rotary kilns are the reactors facilitating the chemical reaction between the gas and solid phases usually at high temperatures.
This book, which is written by an expert in the field, describes the principles of the rotary reactor and the mode of its operation. These reactors are widely used in various chemical process industries (food, pharmaceuticals) and metallurgical industries.
The book defines the physiochemical aspects of the rotart reactors and provides theoretical equations of their operation.
The first part of this book presents the fundamentals; solid movement, conversion of solids, and heat transfer. The middle part of the book applies these equations to a variety of processes which have been developed so far, and shows how they are used. In its last part, conceptual designs of novel rotary reactors are proposed, which performance characteristics are predicted on the basis of above equations, especially, in gasification of solid wastes.
- Defines the rotary reactors and their mode of operation.
- Defines all operating parameters and gives equations to predict the operation of rotary reactors under various conditions.
- Includes a number of practical examples from various industrial applications (metallurgical waste treatment etc).

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Each volume comprises one enzyme class, sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.

This book presents a comprehensive collection of various in situ and ex-situ soil remediation regimes that employ natural or genetically modified microbes, plants, and animals for the biodegradation of toxic compounds or hazardous waste into simpler non-toxic products. These techniques are demonstrated to be functionally effective in connection with physical, chemical, and biological strategies. Soil and water contamination through heavy metals, hydrocarbons and radioactive wastes is of global concern, as these factors have cumulative effects on the environment and human health through food-chain contamination. The book discusses the utilization of algae, plants, plant-associated bacteria, fungi (endophytic or rhizospheric) and certain lower animals for the sustainable bioremediation of organic and inorganic pollutants. In addition, it explores a number of more recent techniques like biochar and biofilms for carbon sequestration, soil conditioning and remediation, and water remediation. It highlights a number of recent advances in nanobioremediation, an emerging technology based on biosynthetic nanoparticles. Lastly, it presents illustrative case studies and highlights the successful treatment of polluted soils by means of these strategies.

This volume presents detailed descriptions and analyses of the underlying features, issues and suppositions associated with seed and seedling laboratory bioassays presented in a previous volume.It is, however, broader in scope and substance in that the information provided is relevant to all water-soluble compounds released to soil by putative allelopathic living plants and their litter and residues.It is ultimately an attempt to update and expand the practical guidelines for designing laboratory bioassays that have previously been provided in the literature with the hope that the designs of future seed and seedling laboratory bioassays will become more relevant to field systems.Standard references have been included to provide background and additional details.This volume has been written specifically for researchers and their graduate students who are interested in studying plant-plant allelopathic interactions."

This book focuses on the development of stapled peptides, a novel molecular modality used to regulate aberrant intracellular protein-protein interactions (PPIs). The author designs and presents a novel helical peptide stabilization methodology by constructing a chiral cross-linker moiety, namely "chiral center induced peptide helicity (CIH)". The book demonstrates that a precisely positioned carbon chiral center on tether can decisively determine the secondary structure of a peptide, and that the R-configured peptide is helical, while the S-configured peptide is non-helical. Further, it reports that helicity-enhanced R isomer peptides displayed significantly enhanced cell permeability and target binding affinity, as well as tumor inhibition efficiency, in comparison to S isomer peptides. The book will not only advance readers' understanding of the basic principle of stapled peptides, but also accelerate the clinical transformation of stapled peptide drugs.

This book describes the vast opportunity created by unifying science and integrating technology, and recommends transforming ideas for individuals and society. We stand at the threshold of a new renaissance in knowledge based on the structure and behavior of matter from the nanoscale up to the most complex system yet discovered, the human brain. Unification of science based on unity in nature and its holistic investigation will lead to technological convergence and a more efficient societal structure for reaching human goals. In the early decades of the twenty-first century, concentrated effort can bring together nanotechnology, biotechnology, information technology, and new humane technologies based in cognitive science. With proper attention to ethical issues and societal needs, rapid advances in convergent technologies have the potential to enhance both human performance and productivity. Examples of payoffs will include improving work efficiency and learning, enhancing individual sensory and cognitive capabilities, revolutionary changes in healthcare, improving both individual and group efficiency, highly effective communication techniques including brain to brain interaction, perfecting human-machine interfaces, enhancing human capabilities for defense purposes, reaching sustainable development using NBIC tools, and ameliorating the physical and cognitive decline that is common to the aging mind.

This is the first book addressing the convergence of technologies in coherence with social sciences, with a focus on people. Science and technology will increasingly dominate the world, as population, resource exploitation, and potential social conflict grow. Therefore, the successof this convergent technologies priority area is seen as crucial to the future of humanity.

Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also known to playa significant role in inciting animal (human) and insect diseases and as plant growth regulators. Many common toxins have also been isolated from different microbes exhibiting a wide spectrum of biological activity. Toxins are broadly divisible into several characteristic groupings - polyketides, oxygen heterocyclic compounds, pyrons, terpenoidS, amino acids - diketopiperazines, polypeptides etc. Recent research has indicated that these toxins play an important role in plant pathogenesis, disease epidemics, plant breeding, biological control of plant pathogens and insect pests, induced resistance, plant-pathogen interactions etc. Toxins produced by weed pathogens are exploited as lead molecules in developing environmentally friendly herbicides.

This book presents recent research on natural fibers extracted from pineapple leaves. Covering several extraction processes, properties of pineapple leaf fibers and comparisons with other natural fibers, and their applications, it provides up-to-date information on the subject of natural fibers from prominent researchers in academia and industry as well as government/private research laboratories across the world. The book is a comprehensive reference resource for university and college faculties, professionals, postdoctoral research fellows, undergraduate/graduate students, researchers and scientists working in the areas of non-forest product utilization, natural fibers, and biomass materials.

Among the major challenges facing society today, seeking renewable alternatives to petroleum-based fuels and manufactured goods is critically important to reducing society's dependency on petroleum and tackling environmental issues associated with petroleum use. In recent years there has been considerable research targeted toward the development of plant-derived bioproducts to replace petrochemical feedstocks for both fuel and manufacturing. Plants not only provide a large amount of renewable biomass, but their biochemical diversity also offers many chemical and molecular tools for the production of new products through biotechnology. Plant Bioproducts is an introduction to the production and application of plant bioproducts, including biofuels, bioplastics, and biochemicals for the manufacturing sector. Contributing authors examine various bioproducts with respect to their basic chemistry, relationship to current petrochemical-based products, and strategies for their production in plants. Chapters cover the integrated roles of agronomy, plant breeding, biotechnology, and biorefining in the context of bioproduct development. Environmental, economic, ethical, and social issues surrounding bioproducts, including the use of genetically modified crops, challenges to food security, and consumer acceptance, are also covered.