This detailed volume provides background on recent new technology developments highlighting the potential of the genomic era in wheat breeding with invaluable instruction on the methodology, which is complemented by overview chapters on the status of new technology application in major wheat production countries. The topics, addressed by internationally renowned scientists active in the field, cover methods underpinning the latest developments in the field of wheat biotechnology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Wheat Biotechnology: Methods and Protocols serves as a vital resource for scientists working to breed future high-yielding wheat varieties to sustain a growing population in an increasingly unpredictable world.

This volume deals with "Microbial Production of L-Amino Acids" and presents five comprehensive, expert and actual review articles on the modern production of Amino Acids by application of biotechnologically optimized microorganisms. This includes not only the modern techniques of enzyme, metabolic and transport engineering but also sophisticated analytical methods like metabolic flux analysis and subsequent pathway modeling. A general review about industrial processes of Amino Acid production provides a comprehensive overview about recent strain development as well as fermentation technologies. It was our special interest to focus the other articles on the most important and best selling amino acids on the world market i.e. L-Glutamate, L-Lysine and L-Threonine. The authors of this special volume have contributed significantly to the progress of Amino Acid biotechnology in the last decades and earn our special gratitude and admiration for their expert review articles.

Organoselenium Chemistry is a unique resource in this branch of organic/organometallic chemistry. The authors give an overview of synthesis strategies, introduce bioactive and environmentally friendly organoselenium compounds and discuss their applications from organic synthesis to the clinic.

For many years the use of chemical agents such as pesticides and herbicides has been effective in controlling the many varieties of pests that infest both agricultural crops and backyard gardens. However, these pests are gradually becoming resistant to these agents, because the agents themselves are acting as selective factors making the pests better and better able to resist and persist. As a result, the use of biological controlling agents is increasing.
This book is a comprehensive and authoritative handbook of biological control.
Key Features
* Introduction (preface plus 2 chapters)
* Principles and processes (12 chapters)
* Agents, biology, and methods (6 chapters)
* Applications (10 chapters)
* Research (2 chapters)

There is hardly any technical library in the world in which the volumes of the Chemical Formulary (Volumes 1-34) do not occupy a prominent place. Chemists both experienced and beginner, continually refer to them. Volume 33 counts numerous experts among it's contributors, such as Editor-in-chief H. Bennett. It does not duplicate any of the formulas included in previous volumes, but lists a wide array of modern and salable products from all branches of the chemical industries. An excellent reference for formulation problems.

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes that have been sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. Usually each volume comprises one enzyme class, although sometimes the enzyme classes have to be divided into several volumes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"), and now many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created, e.g., "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of approximately 25 volumes. This collection is an indispensable source of information for biochemists, biotechologists, organic and analytical chemists, and food scientist.

My journey into this fascinating field of biotechnology started about 26 years ago at a small biotechnology company in South San Francisco called Genentech. I was very fortunate to work for the company that begat the biotech industry during its formative years. This experience established a solid foundation from which I could grow in both the science and business of biotechnology. After my fourth year of working on Oyster Point Boulevard, a close friend and colleague left Genentech to join a start-up biotechnology company. Later, he approached me to leave and join him in of all places - Oklahoma. He persisted for at least a year before I seriously considered his proposal. After listening to their plans, the opportunity suddenly became more and more intriguing. Finally, I took the plunge and joined this ent- preneurial team in cofounding and growing a start-up biotechnology company. Making that fateful decision to leave the security of a larger company was extremely difficult, but it turned out to be the beginning of an entrepreneurial career that forever changed how I viewed the biotechnology industry. Since that time, I have been fortunate to have cofounded two other biotechnology com- nies and even participated in taking one of them public. During my career in these start-ups, I held a variety of positions, from directing the science, operations, regulatory, and marketing components, to subsequently becoming CEO.

The scope of opportunities in chemical and biomolecular engineering has grown tremendously in recent years. Careers in Chemical and Biomolecular Engineering conveys the breadth and depth of today's chemical and biomolecular engineering practice, and describes the intellectually enriching, socially conscious and financially lucrative opportunities available for such graduates in an ever-widening array of industries and applications. This book aims to help students interested in studying chemical engineering and biomolecular engineering to understand the many potential career pathways that are available in these dynamic fields - and is an indispensable resource for the parents, teachers, advisors and guidance counselors who support them, In addition to 10 chapters that discuss the roles such graduates play in many diverse industries, this book also features 25 Profile articles that share in-depth, first-person insight from industry-leading chemical and biomolecular engineers. These technical professionals discuss their work and educational experiences (in terms of both triumphs and challenges), and share wisdom and recommendations for students pursuing these two dynamic engineering disciplines.

Tingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced since the first edition of this book and the author's software, described here, is now used for teaching and research in 32 different countries. This book comes together with a complete software package with graphical user interface for personal computers, offered free for academic applications. Additionally, this book provides detailed methods for parameter estimation of mass transfer coefficients, bed voidage, particle porosity and isotherms. The author gives examples of how to use the software for predicitons and scale-up. In contrast to the first edition, authors do not need to deal with complicated math. Instead, they focus on how to obtain a few parameters for simulation and how to compare simulation results with experimental data. After reading the detailed descriptions in the book, a reader is able to use the simulation software to investigate chromatographic behavior without doing actual experiments. This book is aimed at readers who are interested in learning about LC behaviors and at those who want to scale up LC for preparative- and large-scale applications. Both academic personnel and industrial practitioners can benefit from the use of the book. This new edition includes: - New models and software for pellicular (cored) beads in liquid chromatography - Introduction of user-friendly software (with graphical user interface) - Detailed descriptions on how to use the software - Step-by-step instructions on parameter estimation for the models - New mass-transfer correlations for parameter estimation - Experimental methods for parameter estimation - Several actual examples using the model for product development and scale-up - Updated literature review

C. Tollnick, G. Seidel, M. Beyer, K. Schugerl: Inverstigations of the Production of Cephalosporin C by Acremonium chrysogenum.- K. Friehs: Plasmid Copy Number and Plasmid Stability.- P.S.J. Cheetham: Bioprocesses for the Manufacture of Ingredients for Foods and Cosmetics.- I. Roy, S. Sharma, M.N.

Biohydrogen is considered the most promising energy carrier and its utilization for energy storage is a timely technology. This book presents latest research results and strategies evolving from an international research cooperation, discussing the current status of Biohydrogen research and picturing future trends and applications.

"Cardiac Tissue Engineering: Methods and Protocols "presents a collection of protocols on cardiac tissue engineering from pioneering and leading researchers around the globe. These include methods and protocols for cell preparation, biomaterial preparation, cell seeding, and cultivation in various systems. Written in the highly successful "Methods in Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, "Cardiac Tissue Engineering: Methods and Protocols "highlights the major techniques, both experimental and computational, for the study of cardiovascular tissue engineering.

The title "Nano Biotechnology for Biomedical and Diagnostics Research" will address research aspects related to nanomaterial in imaging and biological research, nanomaterials as a biosensing tool, DNA nanotechnology, nanomaterials for drug delivery, medicinal and therapeutic application and cytotoxicity of nanomaterials. These topics will be covered by 16 different manuscripts. Amongst the authors that will contribute to the book are major scientific leaders such as S. Weiss - UCLA, I. Willner, and G. Golomb -- HUJI, S. Esener - UCSD, E.C. Simmel - Tech. Univ. Munchen, I. Medintz -- NRL, N. Hildebrandt - Universit Paris and more. The manuscripts in the book intend to present specifically biological, diagnostics and medical problems with their potential solution by nano technology or materials. In this respect this book is unique, since it would arise from the biological problems to the nano technology possible solution and not vice versa.

Drawing on a wide range of interviews and primary and secondary sources, this book investigates the dynamic interactions between national regulatory formation and the global biopolitics of regenerative medicine and human embryonic stem cell science.

This book provides an overview of the Ocimum genus from its genetic diversity to genome sequences, metabolites and their therapeutic utilities. Tulasi, Ocimum tenuiflorum, as a member of the family Lamiaceae, is a sacred plant in India. The plants of this genus Ocimum are collectively referred to as Basil and holy basil is worshipped in the Hindu religion. Basils are reservoirs of diverse terpenoids, phenylpropanoids and flavonoids, in addition to commercially important aromatic essential oils. In 2016, two working groups in India published the genome sequence in two different genotypes of Ocimum tenuiflorum. To help the readers understand the complexities of the genus and different chemotypes, this book accumulates all the available information on this medicinal plant including the genome. The complete knowledge may enable researchers to generate specific chemotypes in basil either through conventional breeding or development of transgenic lines. It also makes it possible to investigate the medicinal nature of holy basil compared to different species of the same genus.

In an ever-increasing domain of activity Amino Acids Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 29 provides a review of literature published during 1996. Comprising a comprehensive review of significant developments at this biology/chemistry interface each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters ranging from current trends in their synthesis and conformational and structural analysis to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries and at the biology/chemistry interface in academia will find this an indispensable reference source.

Volume I contains a brief review of adsorption history and its development for practical purposes up until now. It also presents some important information on adsorbents and catalysts as well as on the methods of their characterization. The part of this volume dealing with practical industrial applications includes chapters presenting advanced technical tools for high capacity adsorption separation of liquid and gas mixtures, development of new adsorbents for removal of hazardous contaminants from combustion flue gases and wastewaters, degasification of coal seams and fabrication of inorganic membranes and their applications. A comprehensive review is also included on contemporary utility of self-assembled monolayers, adsorption proteins and their role in modern industry, adsorption methods in technology of optical fibre glasses, sol-gel technology, solid desiccant dehumidification systems, etc. The articles give both the scientific backgrounds of the phenomena discussed and emphasize their practical aspects.

The chapters give not only brief current knowledge about the studied problems, but are also a source of topical literature on the subject. A comprehensive bibliography on adsorption principles, design data and adsorbent materials for industrial applications for the period 1967-1997 concludes the book.

The central role of RNA in many cellular processes, in biotechnology, and as pharmaceutical agents, has created an interest in experimental methods applied to RNA molecules. This book provides scientists with a comprehensive collection of thoroughly tested up-to-date manuals for investigating RNA-protein complexes "in vitro." The protocols can be performed by researchers trained in standard molecular biological techniques and require a minimum of specialized equipment. The procedures include recommendation of suppliers of reagents.

The central role of RNA in many cellular processes, in biotechnology, and as pharmaceutical agents, has created an interest in experimental methods applied to RNA molecules. This book provides scientists with a comprehensive collection of thoroughly tested up-to-date manuals for investigating RNA-protein complexes "in vitro." The protocols can be performed by researchers trained in standard molecular biological techniques and require a minimum of specialized equipment. The procedures include recommendation of suppliers of reagents.

Six years after the symposium on "Stability and Stabilization of Enzymes," a second symposium, "Stability and Stabilization of Biocatalysts," on which this book is based, was organized. At the symposium, 210 participants representing all continents came together to learn from 150 oral and poster communications.

The volume brings up-to-date the work already going on, and identifies possible breakthroughs in the research.
This timely book therefore presents cutting edge developments in topics such as non-covalent processes in solution, protein engineering and thermophile enzymes, immobilized enzymes, non-conventional media, and whole cells.
An excellent addition to the available literature, it will make a useful contribution to this key area of applied biocatalysis.

The increasing demand for environmentally friendly materials and the need for cheaper fibres points the search in the direction of natural products such as bark, leaves, scales or shells. The aim of this book is to provide a forum to review the recent advances in the area of plant and animal-based composites and identify possible trends for further developments.

Assisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Conformational and Chemical Processes in Protein Folding?, by A. Katrine Wallis and Robert B. Freedman Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins, by Cordelia Schiene-Fischer, Tobias Aumuller and Gunter Fischer Small Heat-Shock Proteins: Paramedics of the Cell, by Gillian R. Hilton, Hadi Lioe, Florian Stengel, Andrew J. Baldwin und Justin L. P. Benesch Allostery in the Hsp70 Chaperone Proteins, by Erik R. P. Zuiderweg, Eric B. Bertelsen, Aikaterini Rousaki, Matthias P. Mayer, Jason E. Gestwicki and Atta Ahmad Hsp90: Structure and Function, by Sophie E. Jackson Extracellular Chaperones, by Rebecca A. Dabbs, Amy R. Wyatt, Justin J. Yerbury, Heath Ecroyd and Mark R. Wilson"