Covers the challenges and obstacles involved in using nano-materials for actual applications. Discusses the latest advancements in the synthesis of various carbon based nano-materials. Self-contained source dedicated to understanding of Carbon nano-materials. Explores the area that satisfy needs of a diverse group of researchers, industrialists, educators and students. Interdisciplinary nature of book content makes it effective to connect the gap between disciplines.

This classroom-tested textbook will assist dental students with their academic research activities and help them to be competitive in today's fast-growing research environment. It is designed as a core text for dental school classes such as Research Methodology and Scientific and Technical Writing, as well as Responsible Conduct of Research (RCR) training, but will also be a valuable resource for students and researchers in related fields, such as the medical sciences and biomedical engineering. The authors start the book by explaining key concepts and common approaches in dental research, both in basic science and clinical dentistry. They then familiarize readers with evidence-based research in dentistry and how to write a systematic review, explain the process of designing and presenting a proposal, discuss reporting results both in scientific and clinical research, and cover ethics in research, highlighting the significance of adherence to ethics both in animal as well as human studies.

This book provides a unified framework for various currently available mathematical models that are used to analyze progression and regression in cancer development, and to predict its dynamics with respect to therapeutic interventions. Accurate and reliable model representations of cancer dynamics are milestones in the field of cancer research. Mathematical modeling approaches are becoming increasingly common in cancer research, as these quantitative approaches can help to validate hypotheses concerning cancer dynamics and thus elucidate the complexly interlaced mechanisms involved. Even though the related conceptual and technical information is growing at an exponential rate, the application of said information and realization of useful healthcare devices are lagging behind. In order to remedy this discrepancy, more interdisciplinary research works and course curricula need to be introduced in academic, industrial, and clinical organizations alike. To that end, this book reformulates most of the existing mathematical models as special cases of a general model, allowing readers to easily get an overall idea of cancer dynamics and its modeling. Moreover, the book will help bridge the gap between biologists and engineers, as it brings together cancer dynamics, the main steps involved in mathematical modeling, and control strategies developed for cancer management. This also allows readers in both medical and engineering fields to compare and contrast all the therapy-based models developed to date using a single source, and to identify unexplored research directions.

This book provides current, comprehensive, and clear explanations of the physics behind medical and biomedical applications of shock waves. Extracorporeal shock wave lithotripsy is one of the greatest medical advances of our time, and its techniques and clinical devices are continuously evolving. Further research continues to improve the understanding of calculi fragmentation and tissue-damaging mechanisms. Shock waves are also used in orthopedics and traumatology. Possible applications in oncology, cardiology, dentistry, gene therapy, cell transfection, transformation of fungi and bacteria, as well as the inactivation of microorganisms are promising approaches for clinical treatment, industrial applications and research. Medical and Biomedical Applications of Shock Waves is useful as a guide for students, technicians and researchers working in universities and laboratories. Chemists, biologists, physicians and veterinarians, involved in research or clinical practice will find useful advice, but also engineers and physicists may benefit from the overview of current research endeavors and future directions. Furthermore, it may also serve to direct manufacturers towards the design of more efficient and safer clinical, industrial and laboratory equipment.

The most up to date book on the topic Suitable for use as a textbook Contains a systematic description of each technique it describes Covers a broad readership, including nanotechnology, biotechnology, biophysics, analytical chemistry, and chemical biology Provides a highly simplified tutorial protocol at the end of each chapter to help readers obtain hands-on experience

This book involves the topics on the frontier of the tissue engineering and regenerative medicine. It transits new ideas, new scientific results, and discusses on the design of the self-organized tissues. This book will have a broader readership, because it provides scientific information for diverse disciplinary fields (biology, material science, engineering, medicine, and life science). More scientists, professors, graduates, undergraduates and researchers would be inspired.This book will provide some 3D structure images that would impress the readers with intuitional and abundant information which includes experimental and simulative results.

This text emphasizes the importance of artificial intelligence techniques in the field of biological computation. It also discusses fundamental principles that can be applied beyond bio-inspired computing. It comprehensively covers important topics including data integration, data mining, machine learning, genetic algorithms, evolutionary computation, evolved neural networks, nature-inspired algorithms, and protein structure alignment. The text covers the application of evolutionary computations for fractal visualization of sequence data, artificial intelligence, and automatic image interpretation in modern biological systems. The text is primarily written for graduate students and academic researchers in areas of electrical engineering, electronics engineering, computer engineering, and computational biology. This book: * Covers algorithms in the fields of artificial intelligence, and machine learning useful in biological data analysis. * Discusses comprehensively artificial intelligence and automatic image interpretation in modern biological systems. * Presents the application of evolutionary computations for fractal visualization of sequence data. * Explores the use of genetic algorithms for pair-wise and multiple sequence alignments. * Examines the roles of efficient computational techniques in biology.

Current Trends in Biomanufacturing focuses on cutting-edge research regarding the design, fabrication, assembly, and measurement of bio-elements into structures, devices, and systems. The field of biomaterial and biomanufacturing is growing exponentially in order to meet the increasing demands of for artificial joints, organs and bone-fixation devices. Rapid advances in the biological sciences and engineering are leading to newer and viable resources, methods and techniques that may providing better quality of life and more affordable health care services. The book covers the broad aspects of biomanufacturing, including: synthesis of biomaterials; implant coating techniques; spark plasma sintering; microwave processing; and cladding, powder metallurgy and electrospinning. The contributors illustrate the recent trends of biomanufacturing, highlighting the important aspects of biomaterial synthesis, and their use as feedstock of fabrication technologies and their characterization, along with their clinical practices. Current Trends in Biomanufacturing updates researchers and scientists the novelties and techniques of the field, as it summarises numerous aspects of biomanufacturing, including synthesis of biomaterials, fabrication of biomedical structures, their in-vivo/ in-vitro, mechanical analysis and associated ISO standards.

This is the first book offering a systematic description of tongue image analysis and processing technologies and their typical applications in computerized tongue diagnostic (CTD) systems. It features the most current research findings in all aspects of tongue image acquisition, preprocessing, classification, and diagnostic support methodologies, from theoretical and algorithmic problems to prototype design and development of CTD systems. The book begins with a very in-depth description of CTD on a need-to-know basis which includes an overview of CTD systems and traditional Chinese medicine (TCM) in order to provide the information on the context and background of tongue image analysis. The core part then introduces algorithms as well as their implementation methods, at a know-how level, including image segmentation methods, chromatic correction, and classification of tongue images. Some clinical applications based on these methods are presented for the show-how purpose in the CTD research field. Case studies highlight different techniques that have been adopted to assist the visual inspection of appendicitis, diabetes, and other common diseases. Experimental results under different challenging clinical circumstances have demonstrated the superior performance of these techniques. In this book, the principles of tongue image analysis are illustrated with plentiful graphs, tables, and practical experiments to provide insights into some of the problems. In this way, readers can easily find a quick and systematic way through the complicated theories and they can later even extend their studies to special topics of interest. This book will be of benefit to researchers, professionals, and graduate students working in the field of computer vision, pattern recognition, clinical practice, and TCM, as well as those involved in interdisciplinary research.

Key features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology science examinations

The last decades have seen remarkable advances in computer-aided design, engineering and manufacturing technologies, multi-variable simulation tools, medical imaging, biomimetic design, rapid prototyping, micro and nanomanufacturing methods and information management resources, all of which provide new horizons for the Biomedical Engineering fields and the Medical Device Industry. Advanced Design and Manufacturing Technologies for Biomedical Devices covers such topics in depth, with an applied perspective and providing several case studies that help to analyze and understand the key factors of the different stages linked to the development of a novel biomedical device, from the conceptual and design steps, to the prototyping and industrialization phases. Main research challenges and future potentials are also discussed, taking into account relevant social demands and a growing market already exceeding billions of dollars. In time, advanced biomedical devices will decisively change methods and results in the medical world, dramatically improving diagnoses and therapies for all kinds of pathologies. But if these biodevices are to fulfill present expectations, today's engineers need a thorough grounding in related simulation, design and manufacturing technologies, and collaboration between experts of different areas has to be promoted, as is also analyzed within this handbook.

This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.

Today, over 500,000 medical technologies are available in hospitals, homes, and community care settings. They range from simple bandages to complex, multi-part body scanners that cost millions of dollars to develop. Yet a typical technology has a lifecycle of just 21 months before an improved product usurps it-the healthcare ecosystem is rapidly advancing and driven by a constant flow of innovation. And those innovations need innovators. With $21 billion made available for investment in the digital healthcare industry in 2020 (a 20x increase on 2010), entrepreneurs, investors, and related actors are entering the healthcare ecosystem in greater numbers than ever before. Last year alone, over 17,000 medical technology patents were filed, the third highest of all patent types. Each of those has a dedicated team of entrepreneurs behind it. Yet with increasingly strict regulations and pharmaceutical giants growing more aggressive, many thousands of entrepreneurs fail before even the patent stage: just 2% secure revenue or adoption. Healthtech Innovation: How Entrepreneurs Can Define and Build the Value of Their New Products is a down-to-earth survival guide for entrepreneurs struggling to secure a strategic position within the healthtech ecosystem. Which is expected that by 2026, the global digital health market size will be around $657 billion. This book is designed to help innovators navigate this complex and newly volatile landscape. It covers business strategy, marketing, funding acquisition, and operation in a global regulatory context. It is written in simple language, evidenced by the latest academic and industry research, and explained using real-world examples and case studies.

This book introduces state-of-the-art experimental and numerical methods and examples for evaluating the drilling performance of engineering and biological materials, particularly in thermal aspects. The authors use a common pathway to present the technological and analytical methods for both industry (metal) drilling and orthopaedic surgery (bone) drilling research, making this book a resource for both industrial and clinical readers who wish to understand the evolution of technologies, techniques and challenges in drilling. The authors also focus on advanced engineering materials, such as titanium alloys and high-strength cast irons, which have broad applications in the automotive, aerospace, medical device and sports industries. This book is a must-read for a broad audience, including engineering students in upper-level undergraduate and graduate courses that involve machining processes; for surgery residents, fellows, and practicing surgeons; and for engineers in the medical device industry who develop new bone cutting tools. Bridges the knowledge on drilling from the manufacturing industry to healthcare; Covers the experimental and modeling aspects of drilling thermal analysis; Includes experimental studies that contain parameters and data that emulate practical production and clinical drilling.

This monograph offers a cross-system exchange and cross-modality investigation into brain-heart interplay. Brain-Heart Interplay (BHI) is a highly interdisciplinary scientific topic, which spreads from the physiology of the Central/Autonomous Nervous Systems, especially Central Autonomic Network, to advanced signal processing and modeling for its activity quantification. Motivated by clinical evidence and supported by recent findings in neurophysiology, this monograph first explores the definition of basic Brain-Heart Interplay quantifiers, and then moves onto advanced methods for the assessment of health and disease states. Non-invasive use of brain monitoring techniques, including electroencephalogram and function Magnetic Resonance Imaging, will be described together with heartbeat dynamics monitoring through pulseoximeter and ECG signals. The audience of this book comprises especially of biomedical engineers and medical doctors with expertise in statistics and/or signal processing. Researchers in the fields of cardiology, neurology, psychiatry, and neuroscience in general may be interested as well.

This book presents the latest cutting edge research, theoretical methods, and novel applications in the field of computational intelligence and computational biological approaches that are aiming to combat COVID-19. The book gives the technological key drivers behind using AI to find drugs that target the virus, shedding light on the structure of COVID-19, detecting the outbreak and spread of new diseases, spotting signs of a COVID-19 infection in medical images, monitoring how the virus and lockdown is affecting mental health, and forecasting how COVID-19 cases and deaths will spread across cities and why. Further, the book helps readers understand computational intelligence techniques combating COVID-19 in a simple and systematic way.

In nowadays aging society, many people require mobility assistance. Sometimes, assistive devices need a certain degree of autonomy when users' disabilities difficult manual control. However, clinicians report that excessive assistance may lead to loss of residual skills and frustration. Shared control focuses on deciding when users need help and providing it. Collaborative control aims at giving just the right amount of help in a transparent, seamless way. This book presents the collaborative control paradigm. User performance may be indicative of physical/cognitive condition, so it is used to decide how much help is needed. Besides, collaborative control integrates machine and user commands so that people contribute to self-motion at all times. Collaborative control was extensively tested for 3 years using a robotized wheelchair at a rehabilitation hospital in Rome with volunteer inpatients presenting different disabilities, ranging from mild to severe. We also present a taxonomy of common metrics for wheelchair navigation and tests are evaluated accordingly. Obtained results are coherent both from a quantitative and qualitative point of view.

This book presents the proceedings of the 3rd International Conference on Radiation Safety & Security in Healthcare Services. The conference was held at Universiti Sains Malaysia in Penang on 19th-20th August 2017.

The first book on Ultrafine bubbles (UFBs). Reviews research done on UFBs. Helpful for readers and researchers interested in the fundamentals of this emerging field

Covers important supramolecules. Contains compilation of the different threads of supramolecular chemistry. Covers important supramolecules. Covers important environmental and biological applications. Covers important techniques at relevant places.

Application of additive manufacturing and tissue engineering in the fields of science and technology enables the manufacturing of biocompatible, customized, reliable, and cost-effective parts, restoring the functionality of a failed human body part. This book offers a platform for recent breakthroughs in additive manufacturing related to biomedical applications. This book highlights some of the top innovations and advances in additive manufacturing and processing technologies that are the future of the manufacturing industry while also presenting current challenges and opportunities regarding the choice of material. This book includes areas of applications such as surgical guides, tissue regeneration, artificial scaffolds, implants, and drug delivery and release. Throughout the book, an emphasis is placed on rapid tooling for engineering applications. Additive Manufacturing of Polymers for Tissue Engineering: Fundamentals, Applications, and Future Advancements acts as a first-hand source of information for academic scholars and commercial manufacturers as they make strategic manufacturing and development plans.

Provides comprehensive review of all different polymers for applications in tissue engineering, biomedical implants, energy storage or conversion, and so forth Discusses advanced strategies in development of scaffolds for tissue engineering Elaborates various advanced fabrication techniques for polymeric devices Explores the nuances in polymer-based batteries and energy harvesting Reviews industrial process development for light weight polymeric syntactic foams