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Books > Medicine > Nursing & ancillary services > Biomedical engineering
Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology.
Presents sensor specification, theory of operation, sensor design, and application criteria Provides background plus specific information for practicing engineers who want to understand sensors Includes a complete chapter on industrial sensor communication protocols Explains temperature sensitivity, how to determine, and how to avoid Discusses how to understand and utilize sensor specifications
The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country's prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant.
Metal-Organic Frameworks for Biomedical Applications is a comprehensive, authoritative reference that offers a substantial and complete treatment of published results that have yet to be critically reviewed. It offers a summary of current research and provides in-depth understanding of the role of metal-organic frameworks in biomedical engineering. The title consists of twenty-two chapters presented by leading international researchers in the field. Chapters are arranged by target-application in biomedical engineering, allowing medical and pharmaceutic specialists to translate current materials and engineering science on metal-organic frameworks into their work.
Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion.
Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration.
The increasing interest in the bio-impedance analysis in various fields has increased the demand for portable and low-cost impedance analyzers that can be used in the field. Simplifying the hardware is crucial to maintaining low-cost and portability, but this is not an easy task due to the need for accurate phase and magnitude measurements. This book discusses different portable impedance analyzers design techniques. Additionally, complete designs using two different approaches are reported. The first approach utilizes a commercially available single chip solution while the second one is based on a new measurement technique that eliminates the need to measure the phase by using a software algorithm to extract it from the magnitude information. Applications to the measurement of fruit bio-impedance are emphasized and compared with measurements from professional stand-alone impedance analyzers.
Describes extensively the design and microfabrication of nanosensors based on nanotechnological tools. Provides a wide range of bioplatforms based on e.g., carbon nanostructures and Describes extensively a large number of application as a part of Nanomaterial based biosensors.
Natural Gums: Extraction, Properties, and Applications provides thorough, methodical coverage of a range of natural gums. These naturally forming polysaccharides or complex carbohydrates offer advantageous properties and a range of possible applications. The book begins by introducing fundamental knowledge regarding natural gums, including structures and properties, functionalization, gelatin behavior, and characterization techniques. Subsequent sections of the book provide in-depth chapters, each guiding the reader through the extraction, properties and applications of a specific gum type, covering plant-based, animal-based, microbial-based, and marine-based natural gums. Finally, the future potential of natural gums, and their implications in a circular economy approach, are considered. This is an informative resource for researchers and advanced students in bio-based materials, polymer science, chemistry, bioengineering, materials science, and food science, as well as industrial scientists and R&D professionals with an interest in natural gums and bio-based materials for advanced applications.
Nanotechnology in Herbal Medicine: Applications and Innovations details how nanomaterials can be utilized to improve the therapeutic mechanisms and key properties of herbal drugs. This book guides the reader through the preparation, properties, applications, benefits and challenges of herbal nanoformulations, helping them solve fundamental and applied problems in the area of novel herbal medicines and drug delivery systems. Herbal drugs play a large role in traditional medicines, which are actively used by many cultures across the globe for the treatment of various illnesses and injuries. Despite their widespread use, herbal medicines may lead to possible health risks due to the lack of information on the chemical composition and permitted dosage.
Handbook of Research on Blockchain Technology presents the latest information on the adaptation and implementation of Blockchain technologies in real world business, scientific, healthcare and biomedical applications. The book's editors present the rapid advancements in existing business models by applying Blockchain techniques. Novel architectural solutions in the deployment of Blockchain comprise the core aspects of this book. Several use cases with IoT, biomedical engineering, and smart cities are also incorporated. As Blockchain is a relatively new technology that exploits decentralized networks and is used in many sectors for reliable, cost-effective and rapid business transactions, this book is a welcomed addition on existing knowledge. Financial services, retail, insurance, logistics, supply chain, public sectors and biomedical industries are now investing in Blockchain research and technologies for their business growth. Blockchain prevents double spending in financial transactions without the need of a trusted authority or central server. It is a decentralized ledger platform that facilitates verifiable transactions between parties in a secure and smart way.
This book describes the future of microscopically small medical devices and how to locate a lab to start conducting your own do-it-yourself microelectromechanical systems (MEMS) research in one of the many national, international, government, and other regional open use facilities, where you can quickly begin designing and fabricating devices for your applications. You will learn specific, tangible information on what MEMS are and how a device is fabricated, including what the main types of equipment are in these facilities. The book provides advice on working in a cleanroom, soft materials, collaboration, intellectual property and privacy issues, regulatory compliance, and how to navigate other issues that may arise. This book is primarily aimed at researchers and students who work at universities without MEMS facilities, and small companies who need access to MEMS resources.
This book offers a comprehensive and inclusive insight into the history of prostate cancer and its sufferers. Until recently, little practical help could be offered for men afflicted with the devastating diseases of the genitourinary organs. This is despite complaints of painful urination from aging men being found in ancient medical manuscripts, despite the anatomical discoveries of the European Renaissance and despite the experimental surgical researches of the eighteen and nineteenth centuries. As diseases of the prostate, including prostate cancer, came to be better understood in the early twentieth century, therapeutic nihilism continued as curative radical surgeries and radiotherapy failed. The therapeutic 'turn' came with hormonal therapies, itself a product of the explosive growth of U.S. biomedicine from the 1940s onwards. By the 1990s, prostate cancer screening had become a somewhat ubiquitous but controversial feature of the medical encounter for American men as they aged, which greatly influenced the treatment pathways and identity of the male patient: as victim, as hero, and ultimately, as consumer.
Biopolymer-Based Formulations: Biomedical and Food Applications presents the latest advances in the synthesis and characterization of advanced biopolymeric formulations and their state-of-the-art applications across biomedicine and food science. Sections cover the fundamentals, applications, future trends, environmental, ethical and medical considerations, and biopolymeric architectures that are organized in nano, micro and macro scales. The final section of the book focuses on novel applications and recent developments. This book is an essential resource for researchers, scientists and advanced students in biopolymer science, polymer science, polymer chemistry, polymer composites, plastics engineering, biomaterials, materials science, biomedical engineering, and more. It will also be of interest to R&D professionals, scientists and engineers across the plastics, food, biomedical and pharmaceutical industries.
Neural Networks Modelling and Control: Applications for Unknown Nonlinear Delayed Systems in Discrete Time focuses on modeling and control of discrete-time unknown nonlinear delayed systems under uncertainties based on Artificial Neural Networks. First, a Recurrent High Order Neural Network (RHONN) is used to identify discrete-time unknown nonlinear delayed systems under uncertainties, then a RHONN is used to design neural observers for the same class of systems. Therefore, both neural models are used to synthesize controllers for trajectory tracking based on two methodologies: sliding mode control and Inverse Optimal Neural Control. As well as considering the different neural control models and complications that are associated with them, this book also analyzes potential applications, prototypes and future trends.
Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.
These proceedings present the latest information on regulations and standards for medical and non-medical devices, including wearable robots for gait training and support, design of exoskeletons for the elderly, innovations in assistive robotics, and analysis of human-machine interactions taking into account ergonomic considerations. The rapid development of key mechatronics technologies in recent years has shown that human living standards have significantly improved, and the International Conference on Wearable Sensor and Robot was held in Hangzhou, China from October 16 to 18, 2015, to present research mainly focused on personal-care robots and medical devices. The aim of the conference was to bring together academics, researchers, engineers and students from across the world to discuss state-of-the-art technologies related to various aspects of wearable sensors and robots.
Medical Data Sharing, Harmonization and Analytics serves as the basis for understanding the rapidly evolving field of medical data harmonization combined with the latest cloud infrastructures for storing the harmonized (shared) data. Chapters cover the latest research and applications on data sharing and protection in the medical domain, cohort integration through the recent advancements in data harmonization, cloud computing for storing and securing the patient data, and data analytics for effectively processing the harmonized data.
This book presents state-of-the-art experimental and modelling techniques for skin biophysics that are currently used in academic and industrial research. It also identifies current and future challenges, as well as a growing number of opportunities in this exciting research field. The book covers the basics of skin physiology, biology, microstructural and material properties, and progressively introduces the reader to established experimental characterisation protocols and modelling approaches. Advanced topics in modelling theories and numerical implementation are also presented. The book focusses especially on: 1. Basic physiology, molecular biology, microstructural and material properties of the skin. 2. Experimental characterisation techniques for the skin (including imaging): in vivo and in vitro techniques and combination of those with in silico approaches. 3. State-of-the-art constitutive models of the skin: elastic, anelastic and mechanobiological formulations (e.g. growth, ageing, healing). 4. Applications: mechanics, damage, biological growth, healing, ageing and skin tribology. This book is addressed to postgraduate students in biomedical/mechanical/civil engineering, (bio)physics and applied mathematics, postdoctoral researchers, as well as scientists and engineers working in academia and industry engaged in skin research, particularly, if at the cross-roads of physical experiments, imaging and modelling. The book is also be of interest to clinicians/biologists who wish to learn about the possibilities offered by modern engineering techniques for skin science research and, by so doing, provide them with an incentive to broaden their outlook, engage more widely with the non-clinical research communities and, ultimately, help cross-fertilising new ideas that will lead to better treatment plans and engineering solutions.
The book reports on advanced topics in the areas of wearable robotics research and practice. It focuses on new technologies, including neural interfaces, soft wearable robots, sensors and actuators technologies, and discusses important regulatory challenges, as well as clinical and ethical issues. Based on the 4th International Symposium on Wearable Robotics, WeRob2018, held October 16-20, 2018, in Pisa, Italy, the book addresses a large audience of academics and professionals working in government, industry, and medical centers, and end-users alike. It provides them with specialized information and with a source of inspiration for new ideas and collaborations. It discusses exemplary case studies highlighting practical challenges related to the implementation of wearable robots in a number of fields. One of the focus is on clinical applications, which was encouraged by the colocation of WeRob2018 with the International Conference on Neurorehabilitation, INCR2018. Additional topics include space applications and assistive technologies in the industry. The book merges together the engineering, medical, ethical and political perspectives, thus offering a multidisciplinary, timely snapshot of the field of wearable technologies.
Provides derivation of the models used for calculating the risk and hazard of central oxygen toxicity Improves oxygen diving procedures described in the US Navy Diving Manual Includes procedures applicable to undertaking nitrox dives in combination with oxygen dives Pitches the material at highest technology readiness levels i.e. 9 TRL Aims to increase tactical capabilities of conducting diving special operations
This textbook introduces the concepts and tools that biomedical and chemical engineering students need to know in order to translate engineering problems into a numerical representation using scientific fundamentals. Modeling concepts focus on problems that are directly related to biomedical and chemical engineering. A variety of computational tools are presented, including MATLAB, Excel, Mathcad, and COMSOL, and a brief introduction to each tool is accompanied by multiple computer lab experiences. The numerical methods covered are basic linear algebra and basic statistics, and traditional methods like Newton's method, Euler Integration, and trapezoidal integration. The book presents the reader with numerous examples and worked problems, and practice problems are included at the end of each chapter.
This book provides readers with an introduction to the materials and devices necessary for flexible sensors and electronics, followed by common techniques for fabrication of such devices and system-level integration. Key insights into fabrication and processing will guide readers through the tradeoff choices in designing such platforms. A comprehensive review of two specific, flexible bioelectronic platforms, related to smart bandages for wound monitoring and thread-based diagnostics for wearable health, will demonstrate practical application at the system level. The book also provides a unique electrical engineering perspective by reviewing circuit architectures for low noise signal conditioning of weak signals from sensors,, and for low power analog to digital converters for signal acquisition. To achieve energy autonomy, authors provide several example of CMOS energy harvesting front end circuits and voltage boosters. Beyond circuit architectures, the book also provides a review of the modern theory of sampling and recovery of sparse signals, also known as compressed sensing. They then highlight how these principles can be leveraged for design and implementation of efficient signal acquisition hardware and reliable processing of acquired data for flexible electronic platforms. |
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