Biotribology includes tribological phenomena of natural and implant surface interactions under relative motion in the human body. Biotribology: Emerging Technologies and Applications disseminates ideas and research trends in biotribology and presents pioneering recent research advances impacting the field, focusing on the roles of mathematics, chemistry, physics, materials, and mechanical engineering. Discusses lubrication of joint replacements, computational modeling of biotribology and multibody biomechanical models Describes metal-organic frameworks, medical friction pairs, and electrochemical techniques to tribocorrosion tests Covers state of the art and future technological developments and applications, as well as challenges and opportunities Biotribology is an important and growing field, and the topics covered in this book will be of great interest to the international tribology community, appealing to readers working in the fields of materials science, biomedical engineering, biotechnology, mechanical engineering, and related areas.

Explore important research approaches and concepts within diagnostic radiography Provide contemporary evidence-based practice regarding mixed method approaches Provide a clear and 'how to guide' for understanding key research principles in a wide range of radiographic settings Evaluate the impact of research on patients and the radiographer-patient relationship

Biomaterials and Materials for Medicine: Innovations in Research, Devices, and Applications provides an application-oriented summary of innovations in this rapidly evolving field, offering a view of various directions in biomaterials and medical materials and their advanced uses. Highlights vascular, orthopedic, skin tissue engineering, and nerve tissue engineering biomaterials, including the latest research on therapeutic devices and implants Introduces special stent materials for palliative treatment of esophageal cancer and related technologies of surface modification Discusses use of biomaterials and related designs in drug targeting and controlled release Describes wearable biomedical devices, biomimetic materials, and micronscale and nanoscale biomaterials Details the theoretical calculation and computer simulation of biomaterials as a complementary discipline with physical experimental science This book is aimed at an interdisciplinary group of researchers working on development and application of biomaterials for medical applications in the fields of materials scientists, biomedical engineering, and medicine.

Covers evolutionary approaches to solve optimization problems in biomedical engineering. Discusses IoT, Cloud computing, data analytics in healthcare informatics. Provides computational intelligence-based solution for diagnosis of diseases. Reviews modelling and simulations in designing of biomedical equipment. Promotes machine learning based approaches to improvements in biomedical engineering problems.

Blood microcirculation is essential to our bodies for the successful supply of nutrients, waste removal, oxygen delivery, homeostasis, controlling temperature, wound healing, and active immune surveillance. This book provides a physical introduction to the subject and explores how researchers can successfully describe, understand, and predict behaviours of blood flow and blood cells that are directly linked to these important physiological functions. Using practical examples, this book explains how the key concepts of physics are related to blood microcirculation and underlie the dynamic behavior of red blood cells, leukocytes, and platelets. This interdisciplinary book will be a valuable reference for researchers and graduate students in biomechanics, fluid mechanics, biomedical engineering, biological physics, and medicine. Features: The first book to provide a physical perspective of blood microcirculation Draws attention to the potential of this physical approach for novel applications in medicine Edited by specialists in this field, with chapter contributions from subject area specialists

In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice. Utilisation of advanced early and predictive diagnostics, targeted prevention and personalised medical approaches could enable the elderly subpopulation to reach the 100-year age limit in good physical and mental health, as actively contributing members of society. This task requires intelligent political regulations and creation of new guidelines to advance current healthcare systems. In this book, we will collect contributions from several geopolitical regions of Europe, Asia and USA that provide expert opinion on healthcare organisation and outlook as well as economical aspects of personalised medicine.

Introduces important recent technological advancements in the field Describes the various techniques, platforms, and tools used in biomedical deep learning systems Includes informative case studies that help to explain the new technologies

This work represents an inventive attempt to apply recent advances in nanotechnology to identify and characterise novel polymer systems for drug delivery through the skin. Atomic force microscopy (AFM) measurements of the nanoscale mechanical properties of topical, drug-containing polymeric films enabled the author to identify optimal compositions, in terms of flexibility and substantivity, for application to the skin. To elucidate the enhanced drug release from polyacrylate films incorporating medium chain triglycerides, the author combined AFM studies with the complementary technique of Raman micro-spectroscopy. This experimental strategy revealed that the significant increase in the drug released from these films is the result of a nanoscale two-phase structure. Finally, in experiments examining the microporation of skin using femtosecond laser ablation, the author demonstrated that the threshold at which the skin's barrier function is undermined can be dramatically reduced by the pre-application of ink. The approach allows thermal damage at the pore edge to be minimised, suggesting a very real potential for substantially increasing drug delivery in a minimally invasive fashion.

The first book on Ultrafine bubbles (UFBs). Reviews research done on UFBs. Helpful for readers and researchers interested in the fundamentals of this emerging field

In this book, leading authors in the field discuss development of Ambient Assisted Living. The contributions have been chosen and invited at the 5th AAL congress, Berlin. It presents new technological developments which support the autonomy and independence of individuals with special needs. As the technological innovation raises also social issues, the book addresses micro and macro economical aspects of assistive systems and puts an additional emphasis on the ethical and legal discussion. The presentation is supported by real world examples and applications.

The aim of this book is to present new computational techniques and methodologies for the analysis of the clinical, epidemiological and public health aspects of SARS-CoV-2 and COVID-19 pandemic. The book presents the use of soft computing techniques such as machine learning algorithms for analysis of the epidemiological aspects of the SARS-CoV-2. This book clearly explains novel computational image processing algorithms for the detection of COVID-19 lesions in lung CT and X-ray images. It explores various computational methods for computerized analysis of the SARS-CoV-2 infection including severity assessment. The book provides a detailed description of the algorithms which can potentially aid in mass screening of SARS-CoV-2 infected cases. Finally the book also explains the conventional epidemiological models and machine learning techniques for the prediction of the course of the COVID-19 epidemic. It also provides real life examples through case studies. The book is intended for biomedical engineers, mathematicians, postgraduate students; researchers; medical scientists working on identifying and tracking infectious diseases.

Choice Recommended Title, January 2021 This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective

FUNDAMENTALS OF BIOSTATISTICS leads you through the methods, techniques, and computations of statistics necessary for success in the medical field. Every new concept is developed systematically through completely worked out examples from current medical research problems.

Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

This title gives an overview of composites and biocomposites. It discusses the history of CaPO4/ /polymer biocomposites and hybrid biomaterials, as well as analyzing the latest developments in the field. It also covers bioactivity and biodegradation of CaPO4-based biomaterials.

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention.

Value-Added Biocomposites: Technology, Innovation, and Opportunity explores advances in research, processing, manufacturing, and novel applications of biocomposites. It describes the current market situation, commercial competition, and societal and economic impacts and advantages of substituting biocomposites for conventional composites, including natural fibers and bioplastics. FEATURES Discusses manufacturing and processing procedures that focus on improving physical, mechanical, thermal, electrical, chemical, and biological properties and achieving required specifications of downstream industries and customers Analyzes the wide range of available base materials and fillers of biocomposites and bioplastics in terms of the strength and weaknesses of materials and economic potential in the market Displays special and unique properties of biocomposites in different market sectors Showcases the insight of expert scientists and engineers with first-hand experience working with biocomposites across various industries Covers environmental factors, life cycle assessment, and waste recovery Combining technical, economic, and environmental topics, this work provides researchers, advanced students, and industry professionals a holistic overview of the value that biocomposites add across a variety of engineering applications and how to balance research and development with practical results.

Management in the Age of Digital Business Complexity focuses on how the digital age is changing management and vastly speeding up complexity dynamics. The recent coevolution of technologies has dramatically changed in just a few years how people and firms learn, communicate, and behave. Consequently, the process of how firms coevolve and the speed at which they coevolve has been dramatically changed in the digital age, and managerial methods are lagging way behind. Combining his own expertise with that of a number of specialist and international co-authors, McKelvey conveys how companies that fall behind digitally can quickly be driven out of business. The book has been created for academics seeking to upgrade management thinking into the modern digital age and vastly improve the change capabilities of firms facing digital-oriented competition.

Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers.

Argues that developments in biomedicine in China should be at the center of our understanding of biomedicine, not at the periphery Today China is a major player in advancing the frontiers of biomedicine, yet previous accounts have examined only whether medical ideas and institutions created in the West were successfully transferred to China. This is the firstbook to demonstrate the role China played in creating a globalized biomedicine between 1850 and 1950. This was China's "Century of Humiliation" when imperialist powers dominated China's foreign policy and economy, forcing it to join global trends that included limited public health measures in the nineteenth century and government-sponsored healthcare in the twentieth. These external pressures, combined with a vast population immiserated by imperialism and the decline of the Chinese traditional economy, created extraordinary problems for biomedicine that were both unique to China and potentially applicable to other developing nations. In this book, scholars based in China, the United States, and the United Kingdom make the case that developments in biomedicine in China such as the discovery of new diseases, the opening of the medical profession to women, the mass production of vaccines, and the delivery ofhealthcare to poor rural areas should be at the center of our understanding of biomedicine, not at the periphery. CONTRIBUTORS: Daniel Asen, Nicole Barnes, Mary Augusta Brazelton, Gao Xi , He Xiaolian, Li Shenglan, David Luesink, William H. Schneider, Shi Yan, Yu Xinzhong, DAVID LUESINK is Assistant Professor of History at Sacred Heart University. WILLIAM H. SCHNEIDER is Professor Emeritus of History and Medical Humanities at Indiana University Purdue University Indianapolis. ZHANG DAQING is Professor and Director, Institute of Medical Humanities at Peking University in Beijing.

Insect derived enzymes - a treasure for white biotechnology and food biotechnology. Insect-derived chitinases. Cellulases from insects. Optimization of Insect Cell Based Protein Production Processes - Expression Systems, Online Monitoring, Scale-Up. Insect antenna-based biosensors for in situ detection of volatiles. Y-linked markers for improved population control of the tephritid fruit fly pest, Anastrepha suspensa. Transgenic Approaches to Western Corn Rootworm Control. Tribolium castaneum as a model for high-throughput RNAi screening. Aphid-proof plants: Biotechnology-based approaches for aphid control.