This book addresses biometrics from a biomedical engineering point of view. Divided into five sections, it discusses topics including the influence of pathologies on various biometric modalities (e.g. face, iris, fingerprint), medical and security biometrics, behavioural biometrics, instrumentation, wearable technologies and imaging. The final chapters also present a number of case studies. The book is suitable for advanced graduate and postgraduate students, engineers and researchers, especially those in signal and image processing, biometrics, and biomedical engineering.

This book examines multi-quantum magnetic resonance imaging methods and the diagnostics of brain disorders. It consists of two Parts. The part I is initially devoted towards the basic concepts of the conventional single quantum MRI techniques. It is supplemented by the basic knowledge required to understand multi-quantum MRI. Practical illustrations are included both on recent developments in conventional MRI and the MQ-MRI. This is to illustrate the connection between theoretical concepts and their scope in the clinical applications. The Part II initially sets out the basic details about quadrupole charge distribution present in certain nuclei and their importance about the functions they perform in our brain. Some simplified final mathematical expressions are included to illustrate facts about the basic concepts of the quantum level interactions between magnetic dipole and the electric quadrupole behavior of useful nuclei present in the brain. Selected practical illustrations, from research and clinical practices are included to illustrate the newly emerging ideas and techniques. The reader should note that the two parts of the book are written with no interdependence. One can read them quite independently.

This book presents a road map for applying the stages in conceptualization, evaluation, and testing of biomedical devices in a systematic order of approach, leading to solutions for medical problems within a well-deserved safety limit. The issues discussed will pave the way for understanding the preliminary concepts used in modern biomedical device engineering, which include medical imaging, computational fluid dynamics, finite element analysis, particle image velocimetry, and rapid prototyping. This book would undoubtedly be of use to biomedical engineers, medical doctors, radiologists, and any other professionals related to the research and development of devices for health care.

Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development. This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation design, process optimization and control, new PAT-monitoring tools, multivariate image analysis, process scale-down and development using small-scale freeze-dryers, use of CFD for equipment design, and development of continuous processes. This book is for industry professionals, including chemical engineers and pharmaceutical scientists.

This book gathers full papers presented at the VipIMAGE 2019-VII ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing-held on October 16-18, 2019, in Porto, Portugal. It discusses cutting-edge methods, findings, and applications related to 3D vision, bio- and medical imaging, computer-aided diagnosis, image enhancement, image processing and analysis, virtual reality, and also describes in detail advanced image analysis techniques, such as image segmentation and feature selection, as well as statistical and geometrical modeling. The book provides both researchers and professionals with extensive and timely insights into advanced imaging techniques for various application purposes.

With the increasing worldwide prevalence of tissue damage, there is an urgent, growing demand for tissue engineering materials to mimic autologous tissue for surgical repair. Many attempts have been made to produce long-lasting, biocompatible implants. To overcome the mechanical and biological limitations of synthetic implants, the development of native macromolecule-based 3D substitutes as alternatives has been the latest focus. Advances in nanofabrication and controlled-release technology have vastly improved the potential of such 3D substitutes in influencing cell and tissue performance. This book is an overview of the current state of knowledge in the field of native macromolecule-based 3D substitutes for the repair of several tissue types, including bone, cartilage, vascular, and many more.

This book is a detailed reference on biomedical applications using Deep Learning. Because Deep Learning is an important actor shaping the future of Artificial Intelligence, its specific and innovative solutions for both medical and biomedical are very critical. This book provides a recent view of research works on essential, and advanced topics. The book offers detailed information on the application of Deep Learning for solving biomedical problems. It focuses on different types of data (i.e. raw data, signal-time series, medical images) to enable readers to understand the effectiveness and the potential. It includes topics such as disease diagnosis, image processing perspectives, and even genomics. It takes the reader through different sides of Deep Learning oriented solutions. The specific and innovative solutions covered in this book for both medical and biomedical applications are critical to scientists, researchers, practitioners, professionals, and educations who are working in the context of the topics.

This book is open access under a CC BY-NC 2.5 license. This book covers the latest in snow sport epidemiology, snow sport injuries and treatment, and biomechanical/mechanical engineering related to snow sports injuries (mechanisms of injury, injury prevention by equipment design, injury prevention by design of resort features, and more). It brings together a collection of papers from the International Congress on Ski Trauma and Safety (the biennal meeting of the International Society for Skiing Safety) and presents the latest research on the effectiveness of winter sports equipment, the behavior of winter sports participants, and the epidemiology and biomechanics of winter sports injuries. This is an ideal book for researchers and professionals working in the field of sports medicine and safety. This book also: Covers the latest body of literature dealing with safety in winter sports as well as the prevention and treatment of injuries sustained by participants in these activities Broadens readers' understanding of snow sport injury prevention research Illustrates ways safety standards for snow sports can be improved based on evidence-based research.

Functional Marine Biomaterials: Properties and Applications provides readers with the latest information on the diverse marine environment as a resource for many new substances, including biopolymers, bioceramics, and biominerals. As recent advances and funding has enabled scientists to begin harnessing many of these materials for biomedical applications from drug delivery to bone tissue engineering and biosensors, this important new text provides readers with a comprehensive review of these materials and their functional applications in the biomedical field. Chapters discuss the properties of the main classes of functional marine biomaterials, applications of marine products in tissue engineering, applications in drug delivery systems, and the role of marine derived materials in medical devices.

Complex multivariate problems are frequently encountered in many scientific disciplines and it can be very difficult to obtain meaningful results. Permutation and nonparametric combination methods provide flexible solutions to complex problems by reducing the problem down to a set of simpler sub-problems. The author presents a novel but well tested approach using real examples taken from biomedical research. Statistical analyses are performed in a nonparametric setting, so that no assumptions need be made about the underlying distribution and the dependence relations between variables.

• Provides a clear exposition of the use of multivariate permutation testing, with emphasis on the use of nonparametric combination methodology.
• Explores a growing area of research with many practical applications, notably in biostatistics.
• Numerous case studies and examples help to illustrate the theory.
• Provides solutions to multi-aspect problems, to problems with missing data, analysis of factorial designs and repeated measures.
• Explains the analysis of categorical, ordered categorical, binary, continuous, and mixed variables in both an experimental and an observational context.
• NPC-Test^csoftware, SAS macros, S-Plus code, and datasets are available on the Web.

A network is a mathematical object consisting of a set of pointsthat are connected to each other in somefashion by lines. It turns out thissimple descriptioncorresponds to a bewildering array of systems in the real world, ranging from technological ones such as the Internet and WorldWide Web, biological networks such as that of connections of thenervous systems, food webs or protein interactions, infrastructural systems such as networks of roads, airports or the power-grid, to patterns of social and professional relationships such as friendship, sex partners, network ofHollywood actors, co-authorship networks and many more.

Recent years have witnessed a substantial amount of interest within thescientific community in the properties of these networks. The emergenceof the internet in particular, coupled with the widespread availability ofinexpensive computing resources has facilitated studies ranging fromlarge scale empirical analysis of networks in the real world, to the developmentof theoretical models and tools to explore the various properties of these systems.The study of networks is broadly interdisciplinary and central developments haveoccurred in many fields, including mathematics, physics, computer and informationsciences, biology and the social sciences.

This book brings together a collectionof cutting-edge research in the field from adiversearray of researchers ranging fromphysicists to social scientists and presents them in acoherent fashion, highlighting thestrong interconnections between the different areas. Topicsincluded are social networks and social media, opinion and innovation diffusion, biological and health-related networks, language networks, as well as network theory, community detection, or growth models for Complex Networks."

There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.

This book explores novel methods for implementing X-ray diffraction technology as an imaging modality, which have been made possible through recent breakthroughs in detector technology, computational power, and data processing algorithms. The ability to perform fast, spatially-resolved X-ray diffraction throughout the volume of a sample opens up entirely new possibilities in areas such as material analysis, cancer diagnosis, and explosive detection, thus offering the potential to revolutionize the fields of medical, security, and industrial imaging and detection. Featuring chapters written by an international selection of authors from both academia and industry, the book provides a comprehensive discussion of the underlying physics, architectures, and applications of X-ray diffraction imaging that is accessible and relevant to neophytes and experts alike. Teaches novel methods for X-ray diffraction imaging Comprehensive and self-contained discussion of the relevant physics, imaging techniques, system components, and data processing algorithms Features state-of-the-art work of international authors from both academia and industry. Includes practical applications in the medical, industrial, and security sectors

Recent advances in nanotechnology has led the nanomaterials into the realm of sensing applications. This descriptive book utilizes a multi-disciplinary approach to provide extensive information about sensors and elucidates the impact of nanotechnology on development of chemical and biosensors for diversified applications. The main focus of this book is not only the inclusion of various research works, which have already been reported in literature, but also to make a potential conclusion about the mechanism behind this. This book will serve as an invaluable tool for both frontline researchers and academicians to work towards the future development of nanotechnology in sensing devices.

This volume covers a wide array of topics that will aid researchers in the task of engineering complex biological systems. This book is divided into three parts: Part One discusses the discovery and identification of relevant biosynthetic pathways for engineering; Part Two looks at the development of genetic tools for manipulating enzymes, biosynthetic pathways, and whole genomes; and Part Three covers the characterization of engineered microbes using targeted and global systems biology tools, as well as in silico models. Chapters explore topics such as leveraging enzyme promiscuity to construct novel biosynthetic pathways; assembling combinatorial multigene pathways for rapid strain optimization; applying 'omics technologies for identifying bottlenecks; and engineering nontraditional host organisms like cyanobacterium and Yarrowia lipolytica. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and authoritative, Microbial Metabolic Engineering: Methods and Protocols is a valuable resource for researchers and scientists interested in engineering and optimizing microbes for a variety of biotechnological applications.

IoT-enabled healthcare technologies can be used for remote health monitoring, rehabilitation assessment and assisted ambient living. Healthcare analytics can be applied to the data gathered from these different areas to improve healthcare outcomes by providing clinicians with real-world, real-time data so they can more easily support and advise their patients. The book explores the application of AI systems to analyse patient data and guide interventions. IoT-based monitoring systems and their security challenges are also discussed. The book is designed to be a reference for healthcare informatics researchers, developers, practitioners, and people who are interested in the personalised healthcare sector. The book will be a valuable reference tool for those who identify and develop methodologies, frameworks, tools, and applications for working with medical big data and researchers in computer engineering, healthcare electronics, device design and related fields.

The global ageing society has significantly increased the need for implant materials, which not only replace damaged or lost tissue but are also able to regenerate it. The field of bioactive glasses has been expanding continuously over recent years as they have been shown to bond with hard and soft tissue, release therapeutically active ions, and be capable of enhancing bone formation and regeneration. In addition, they are successfully being used to re-mineralise teeth, thereby making bioactive glasses highly attractive materials in both dentistry and medicine. Understanding the multidisciplinary requirements set by the human body's environment and the special characteristics of the different families of bioactive glasses is a key in developing new compositions to novel clinical applications. Bioactive Glasses aims to bridge the different scientific communities associated with the field of bioactive glasses with focus on the materials science point of view. Emerging applications covered include soft tissue regeneration, wound healing, vascularisation, cancer treatment and drug delivery devices. This book provides a comprehensive overview of the latest applications of bioactive glasses for material scientists.

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

New prospects for biomedical and healthcare engineering are being created by the rapid development of Robotic and Artificial Intelligence techniques. Innovative technologies such as Artificial Intelligence, Deep Learning, Robotics, and IoT are currently under huge influence in today's modern world. For instance, a micro-nano robot allows us to study the fundamental problems at a cellular scale owing to its precise positioning and manipulation ability; the medical robot paves a new way for the low-invasive and high-efficient clinical operation, and rehabilitation robotics is able to improve the rehabilitative efficacy of patients. This book aims at exhibiting the latest research achievements, findings, and ideas in the field of robotics in biomedical and healthcare engineering, primarily focusing on the walking assistive robot, telerobotic surgery, upper/lower limb rehabilitation, and radiosurgery. As a result, a wide range of robots are being developed to serve a variety of roles within the medical environment. Robots specializing in human treatment include surgical robots and rehabilitation robots. The field of assistive and therapeutic robotic devices is also expanding rapidly. These include robots that help patients rehabilitate from severe conditions like strokes, empathic robots that assist in the care of older or physically/mentally challenged individuals, and industrial robots that take on a variety of routine tasks, such as sterilizing rooms and delivering medical supplies and equipment, including medications. The objectives of the book are in terms of advancing the state-of-the-art of robotic techniques and addressing the challenging problems in biomedical and healthcare engineering. This book Lays a good foundation for the core concepts and principles of robotics in biomedical and healthcare engineering, walking the reader through the fundamental ideas with expert ease. Progresses on the topics in a step-by-step manner and reinforces theory with a full-fledged pedagogy designed to enhance students' understanding and offer them a practical insight into the applications of it. Features chapters that introduce and cover novel ideas in healthcare engineering like Applications of Robots in Surgery, Microrobots and Nanorobots in Healthcare Practices, Intelligent Walker for Posture Monitoring, AI-Powered Robots in Biomedical and Hybrid Intelligent Systems for Medical Diagnosis, and so on. Deepak Gupta is an Assistant Professor at the Maharaja Agrasen Institute of Technology, GGSIPU, Delhi, India. Moolchand Sharma is an Assistant Professor at the Maharaja Agrasen Institute of Technology, GGSIPU, Delhi, India. Vikas Chaudhary is a Professor at the JIMS Engineering Management Technical Campus, GGSIPU, Greater Noida, India. Ashish Khanna currently works at the Maharaja Agrasen Institute of Technology, GGSIPU, Delhi, India.

This book examines the use of biomedical signal processing-EEG, EMG, and ECG-in analyzing and diagnosing various medical conditions, particularly diseases related to the heart and brain. In combination with machine learning tools and other optimization methods, the analysis of biomedical signals greatly benefits the healthcare sector by improving patient outcomes through early, reliable detection. The discussion of these modalities promotes better understanding, analysis, and application of biomedical signal processing for specific diseases. The major highlights of Biomedical Signal Processing for Healthcare Applications include biomedical signals, acquisition of signals, pre-processing and analysis, post-processing and classification of the signals, and application of analysis and classification for the diagnosis of brain- and heart-related diseases. Emphasis is given to brain and heart signals because incomplete interpretations are made by physicians of these aspects in several situations, and these partial interpretations lead to major complications. FEATURES Examines modeling and acquisition of biomedical signals of different disorders Discusses CAD-based analysis of diagnosis useful for healthcare Includes all important modalities of biomedical signals, such as EEG, EMG, MEG, ECG, and PCG Includes case studies and research directions, including novel approaches used in advanced healthcare systems This book can be used by a wide range of users, including students, research scholars, faculty, and practitioners in the field of biomedical engineering and medical image analysis and diagnosis.

Handbook of Artificial Intelligence in Biomedical Engineering focuses on recent AI technologies and applications that provide some very promising solutions and enhanced technology in the biomedical field. Recent advancements in computational techniques, such as machine learning, Internet of Things (IoT), and big data, accelerate the deployment of biomedical devices in various healthcare applications. This volume explores how artificial intelligence (AI) can be applied to these expert systems by mimicking the human expert's knowledge in order to predict and monitor the health status in real time. The accuracy of the AI systems is drastically increasing by using machine learning, digitized medical data acquisition, wireless medical data communication, and computing infrastructure AI approaches, helping to solve complex issues in the biomedical industry and playing a vital role in future healthcare applications. The volume takes a multidisciplinary perspective of employing these new applications in biomedical engineering, exploring the combination of engineering principles with biological knowledge that contributes to the development of revolutionary and life-saving concepts.

Nanostructured materials are emerging as a new class of materials that exhibit unique microstructures and enhanced mechanical performance. As an outcome of this, these materials have attracted considerable attention in scientific communities all over the world. There is continuous research to facilitate product development, thereby improving product quality and reliability in industry. This volume is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. Special emphasis is given to new applications of nanostructures and nanocomposites in various fields, such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine. The chapters are divided into sections focusing on: Nanoparticles Assembly and Nanostructured Materials Nanocomposites Properties Nanostructured Materials for Biomedical Applications

The volume includes presentations of technological and research accomplishments along with novel approaches in nanomedicine and nanotechnology. It explores the different types of nanomedicinal drugs with their production and commercial significance. Other topics discussed are the use of natural and synthetic nanoparticles for the production of drugs, different types of nanoparticles systems, drug carriers, wound-healing antimicrobial activity, effects of natural materials in nanomedicine, and toxicity of nanoparticles. The valuable information presented in this volume will help to keep those in this field up to date on the key findings, observations, and fabrication of drugs related to nanomedicine and nanotechnology. With chapters written by prominent researchers from academia, industry, and government and private research laboratories across the world, the book will prove to be a rich resource.

This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer

This book focuses on the recent advances in nanomedicine and tissue engineering. It outlines the basic tools and novel approaches that are becoming available in nanomedicine and tissue engineering and considers the full range of nanomedical applications which employ molecular nanotechnology inside the human body, from the perspective of a future practitioner in an era of widely available nanomedicine. Topics include: Health benefits of phytochemicals and application of superparamagnetic nanoparticles for hyperthermia Silver nanoparticles in nanomedicine Optical diagnostic of molecules and cells using nanotechnology Nanoparticulate drug delivery system for antiviral drugs Liposomal drug delivery systems, nanoemulsifying drug delivery system (SNEDS) Functionalization of tissue engineering scaffolds Induction of angiogenesis in scaffolds Many other recent achievements Written by some of the most innovative minds in medicine and tissue engineering, this book considers the full range of nanomedical applications which employ molecular nanotechnology inside the human body and will help professionals understand cutting-edge and futuristic areas of nanomedicine and tissue engineering research. Readers will find insightful discussions on nanostructured intelligent materials and devices that are considered technically feasible and that have a high potential to produce advances in medicine in the near future.