This book highlights the use of LEDs in biomedical photoacoustic imaging. In chapters written by key opinion leaders in the field, it covers a broad range of topics, including fundamentals, principles, instrumentation, image reconstruction and data/image processing methods, preclinical and clinical applications of LED-based photoacoustic imaging. Apart from preclinical imaging studies and early clinical pilot studies using LED-based photoacoustics, the book includes a chapter exploring the opportunities and challenges of clinical translation from an industry perspective. Given its scope, the book will appeal to scientists and engineers in academia and industry, as well as medical experts interested in the clinical applications of photoacoustic imaging.

This book reviews the current knowledge on tunable hydrogels, including the range of different materials and applications, as well as the existing challenges and limitations in the field. It covers various aspects of the material design, particularly highlighting biological responsiveness, degradability and responsiveness to external stimuli. In this book, readers will discover original research data and state-of-the-art reviews in the area of hydrogel technology, with a specific focus on biotechnology and medicine. Written by leading experts, the contributions outline strategies for designing tunable hydrogels and offer a detailed evaluation of the physical and synthetic methods currently employed to achieve specific hydrogel properties and responsiveness. This highly informative book provides important theoretical and practical insights for scholars and researchers working with hydrogels for biomedical and biotechnological applications.

This book focuses on various aspects of research on ageing, including in relation to assistive technology; dignity of aging; how technology can support a greater understanding of the experience of physically aging and cognitive changes; mobility issues associated with the elderly; and emerging technologies. The 80+ age group represents an expanding market, with an estimated worth of GBP21.4 billion a year. Everyone is affected by this shift in demographics - we are getting older and may become carers - and we need to prepare ourselves and adjust our surroundings for longer life. Products, services and environments have been changing in response to the changing population. Presenting international design research to demonstrate the thinking and ideas shaping design, this book is a valuable resource for designers; product developers; employers; gerontologists; and medical, health and service providers; as well as everyone interested in aging.

This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights.

Operation Research methods are often used in every field of modern life like industry, economy and medicine. The authors have compiled of the latest advancements in these methods in this volume comprising some of what is considered the best collection of these new approaches. These can be counted as a direct shortcut to what you may search for. This book provides useful applications of the new developments in OR written by leading scientists from some international universities. Another volume about exciting applications of Operations Research is planned in the near future. We hope you enjoy and benefit from this series!

Dental Implants: Materials, Coatings, Surface Modifications and Interfaces with Oral Tissues provides readers with information on past and contemporary advances in the design and modification of dental implants to enhance osseointegration and biocompatibility. The book begins with a look at the current status of dental implants, materials and fabrication methods. Chapters then cover surface modification techniques and a variety of inorganic, organic and biological coatings. Final sections cover tissue-implant interfaces. Written by a multidisciplinary team of materials scientists, dental clinicians and implantologists, this book is an essential reference for materials scientists, dental practitioners and researchers and students in academia.

This book describes the development of portable, wearable, and highly customizable hand exoskeletons to aid patients suffering from hand disabilities. It presents an original approach for the design of human hand motion assistance devices that relies on (i) an optimization-based kinematic scaling procedure, which guarantees a significant adaptability to the user's hands motion, and (ii) a topology optimization-based design methodology, which allowed the design of a lightweight, comfortable device with a high level of performance. The book covers the whole process of hand exoskeleton development, from establishing a new design strategy, to the construction and testing of hand exoskeleton prototypes, using additive manufacturing techniques. As such, it offers timely information to both researchers and engineers developing human motion assistance systems, especially wearable ones.

This book introduces a variety of well-proven and newly developed nature-inspired optimization algorithms solving a wide range of real-life biomedical and healthcare problems. Few solo and hybrid approaches are demonstrated in a lucid manner for the effective integration and finding solution for a large-scale complex healthcare problem. In the present bigdata-based computing scenario, nature-inspired optimization techniques present adaptive mechanisms that permit the understanding of complex data and altering environments. This book is a voluminous collection for the confront faced by the healthcare institutions and hospitals for practical analysis, storage, and data analysis. It explores the distinct nature-inspired optimization-based approaches that are able to handle more accurate outcomes for the current biomedical and healthcare problems. In addition to providing a state-of-the-art and advanced intelligent methods, it also enlightens an insight for solving diversified healthcare problems such as cancer and diabetes.

This text emphasizes the importance of artificial intelligence techniques in the field of biological computation. It also discusses fundamental principles that can be applied beyond bio-inspired computing. It comprehensively covers important topics including data integration, data mining, machine learning, genetic algorithms, evolutionary computation, evolved neural networks, nature-inspired algorithms, and protein structure alignment. The text covers the application of evolutionary computations for fractal visualization of sequence data, artificial intelligence, and automatic image interpretation in modern biological systems. The text is primarily written for graduate students and academic researchers in areas of electrical engineering, electronics engineering, computer engineering, and computational biology. This book: * Covers algorithms in the fields of artificial intelligence, and machine learning useful in biological data analysis. * Discusses comprehensively artificial intelligence and automatic image interpretation in modern biological systems. * Presents the application of evolutionary computations for fractal visualization of sequence data. * Explores the use of genetic algorithms for pair-wise and multiple sequence alignments. * Examines the roles of efficient computational techniques in biology.

This book gathers revised selected papers from the 3rd International Workshop on Gerontechnology, IWoG 2020, held on October 5-6, 2020, in Evora, Portugal. They reports on cutting-edge technologies and optimized workflows for promoting active aging and assisting and elderly people at home, as well as in healthcare centers. It discusses the main challenges in the development, use and delivery of health care services and technologies. Not only they proposes solutions for improving in practice the monitoring and management of health parameters and age-related diseases, yet they also describes improved approaches for helping seniors in their daily tasks and facilitating their communication and integration with assistive technologies, thus improving their quality of life, as well as their social integration. The book provides health professionals, researchers, and service providers with extensive information on the latest trends in the development and practical application of gerontechnology in elderly care.

This book constitutes the proceedings of the third international conference AsiaHaptics 2018, held in Songdo, Korea. It presents the state-of-the-art of the diverse haptics (touch)-related research, including perception and illusion, development of haptics devices, and applications to a wide variety of fields such as education, medicine, telecommunication, navigation and entertainment. This book is a valuable resource not only for active haptics researchers, but also for general readers wishing to understand the status quo in this interdisciplinary area of science and technology.

This handbook on Artificial Intelligence (AI) in healthcare consists of two volumes. The first volume is dedicated to advances and applications of AI methodologies in specific healthcare problems, while the second volume is concerned with general practicality issues and challenges and future prospects in the healthcare context. The advent of digital and computing technologies has created a surge in the development of AI methodologies and their penetration to a variety of activities in our daily lives in recent years. Indeed, researchers and practitioners have designed and developed a variety of AI-based systems to help advance health and well-being of humans. In this first volume, we present a number of latest studies in AI-based tools and techniques from two broad categories, viz., medical signal, image, and video processing as well as healthcare information and data analytics in Part 1 and Part 2, respectively. These selected studies offer readers practical knowledge and understanding pertaining to the recent advances and applications of AI in the healthcare sector.

Additive Manufacturing and 3D Printing Technology: Principles and Applications consists of the construction and working details of all modern additive manufacturing and 3D-printing technology processes and machines, while also including the fundamentals, for a well-rounded educational experience. The book is written to help the reader understand the fundamentals of the systems. This book provides a selection of additive manufacturing techniques suitable for near-term application with enough technical background to understand the domain, its applicability, and to consider variations to suit technical and organizational constraints. It highlights new innovative 3D-printing systems, presents a view of 4D printing, and promotes a vision of additive manufacturing and applications toward modern manufacturing engineering practices. With the block diagrams, self-explanatory figures, chapter exercises, and photographs of lab-developed prototypes, along with case studies, this new textbook will be useful to students studying courses in Mechanical, Production, Design, Mechatronics, and Electrical Engineering.

Smart Homes (SH) offer a promising approach to assisted living for the ageing population. Yet the main obstacle to the rapid development and deployment of Smart Home (SH) solutions essentially arises from the nature of the SH field, which is multidisciplinary and involves diverse applications and various stakeholders. Accordingly, an alternative to a one-size-fits-all approach is needed in order to advance the state of the art towards an open SH infrastructure. This book makes a valuable and critical contribution to smart assisted living research through the development of new effective, integrated, and interoperable SH solutions. It focuses on four underlying aspects: (1) Sensing and Monitoring Technologies; (2) Context Interference and Behaviour Analysis; (3) Personalisation and Adaptive Interaction, and (4) Open Smart Home and Service Infrastructures, demonstrating how fundamental theories, models and algorithms can be exploited to solve real-world problems. This comprehensive and timely book offers a unique and essential reference guide for policymakers, funding bodies, researchers, technology developers and managers, end users, carers, clinicians, healthcare service providers, educators and students, helping them adopt and implement smart assisted living systems.

This book explores a sampling of the most powerful and enterprising efforts to achieve biotechnological goals by means of various interdisciplinary approaches. From the fabrication of extremely small units to achieve specific objectives through nano-bio-technology, to devices with artificial intelligence, gene therapy for cerebrovascular anomalies, biodegradable plastics, the use of phyto-stem cells in cosmetology, CarT cell immune therapy, targeted therapies for cancer, 3D printed bones developed by the University of Wollongong in Australia, the sickle cell chip developed by IIT Bombay, and innovative sustainable energy solutions, the book includes a colorful spectrum of reviews on current and future biotech products. Gathering contributions by an international team of researchers, this book offers its audience, and particularly younger readers, revealing information on current and upcoming smart technologies.

This volume presents a timely recognition, warning and mapping of the fast approaching wave, or "bio-tsunami", of global socio-technical transformation, built by a much wider spectrum of converging powers, including biotechnology, new agriculture, novel foods, health, quality of life, environment, energy, sustainability, education, knowledge management, and design of smart applications. The book contains eight sections corresponding to different clusters of bioeconomic and socio-technical change, as identified by the editors' "Scanning the Horizon" foresight research; it also offers an integrated view of the future bioeconomy landscape though the convergence of several technologies that affect everyday life. The clusters offer methodologies for forecasting the future bioeconomy, and how these predictions can affect target-setting and the orientation of policies and actions to manage cultural and societal change, and achieve sustainable development in less developed areas. The book will be of interest to researchers, producers, logistics experts, policy makers, regulators, business and financial institutions, and biotechnologists (e.g. geneticists, food experts, etc.).

This book describes the multitude of interactions between plant, soil, and micro-organisms. It emphasizes on how growth and development in plants, starting from seed germination, is heavily influenced by the soil type. It describes the interactions established by plants with soil and inhabitant microbial community. The chapters describe how plants selectively promote certain microorganisms in the rhizospheric ecozone to derive multifarious benefits such as nutrient acquisition and protection from diseases. The diversity of these rhizospheric microbes and their interactions with plants largely depend on plant genotype, soils attributes, and several abiotic and biotic factors. Most of the studies concerned with plant-microbe interaction are focused on temperate regions, even though the tropical ecosystems are more diverse and need more attention. Therefore, it is crucial to understand how soil type and climatic conditions influence the plant-soil-microbes interaction in the tropics. Considering the significance of the subject, the present volume is designed to cover the most relevant aspects of rhizospheric microbial interactions in tropical ecosystems. Chapters include aspects related to the diversity of rhizospheric microbes, as well as modern tools and techniques to assess the rhizospheric microbiomes and their functional roles. The book also covers applications of rhizospheric microbes and evaluation of prospects improving agricultural practice and productivity through the use of microbiome technologies. This book will be extremely interesting to microbiologists, plant biologists, and ecologists.

This book presents a compilation of state-of-the-art work on biomedical and cyber-physical systems in connection with the Internet of Things, and successfully blends theory and practice. The book covers the studies belonging to Biomedical and Cyber-physical System, so it is a unique effort by the research experts, who are divulging in the domain deeply. The book is very easy for the audience, who are doing study in the Biomedical and Cyber-physical System; it helps to read some real-time scenarios from where the reader in general gets many sparking ideas to convert it into the research problems in their studies. This book is of use to solve down the problems of graduate, postgraduate, doctoral industry executives, who are involving in the cutting-edge work of Internet of Things with Biomedical or Cyber-physical System, with the help of real-time solutions, given in the formation of chapters by subject's experts.The key uses of this book are in the area of Internet of Things in connection with Cyber-physical System as well as Biomedical domain.

This book examines the role of nanobiosensors in point-of-care applications for personalized healthcare and management. It begins by discussing various biomaterials that are used for the development of biosensors in medical diagnostics, and reviews advances in their fabrication and the miniaturization of biosensor devices for lab-on-chip analysis. In turn, it explores the rapidly evolving applications of nanomaterials in the context of biomaterial diagnostics. The book also explores the immense potential of biosensors in medical diagnostics, where they are increasingly being used to detect a wide range of biomolecules and biomarkers. In closing, it discusses the current challenges and outlines the future role of nanobiosensors in the development of next-generation point-of-care applications.

This book highlights the complexity of spinel nanoferrites, their synthesis, physio-chemical properties and prospective applications in the area of advanced electronics, microwave devices, biotechnology as well as biomedical sciences. It presents an overview of spinel nanoferrites: synthesis, properties and applications for a wide audience: from beginners and graduate-level students up to advanced specialists in both academic and industrial sectors. There are 15 chapters organized into four main sections. The first section of the book introduces the readers to spinel ferrites and their applications in advanced electronics industry including microwave devices, whereas the second section mainly focus on the synthesis strategy and their physio-chemical properties. The last sections of the book highlight the importance of this class of nanomaterials in the field of biotechnology and biomedical sector with a special chapter on water purification.

This book is the output of Anthropological Survey of India's National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018. The book compiles the independent and collaborative work of 49 scientific personnel. Genomics facilitate the study of genetic constitution and diversity at individual and population levels. Genomic diversity explains susceptibility, predisposition and prolongation of diseases; personalized medicine and longevity; prehistoric demographic events, such as population bottleneck, expansion, admixture and natural selection. This book highlights the heterogeneous, genetically diverse population of India. It shows how the central geographic location of India, played a crucial role in historic and pre-historic human migrations, and in peopling different continents of the world. The book describes the massive task undertaken by AnSI to unearth genomic diversity of India populations, with the use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y -chromosome in 75 communities. The book talks about the 61 maternal and 35 paternal lineages identified through these studies. It brings forth interesting, hitherto unknown findings such as shared mutations between certain communities. This volume is a milestone in scientific research to understand biological diversity of Indian people at genomic level. It addresses the basic priority to identify different genes underlying various inborn genetic defects and diseases specific to Indian populations. This would be highly interesting to population geneticists, historians, as well as anthropologists.

This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering. The aims are to provide the readers, including students, faculty, and all scientists working in academia and industry, new information on bioengineering in cell and tissue research to enhance their understanding and innovation.

Plastic is one of the widely used polymers around the globe since its discovery. It is highly impossible to think the ease of life without the aid of plastic. Every year billion tons of plastic waste gets accumulated in the environment and leads to death of both marine and terrestrial animals. Plastic is very durable and needs around 1000 years to degrade under the natural environment. The present book illustrates the importance and significance of the bioremediation to tackle the problem of plastic waste. Previously, we have reported elite rhizobacterial isolates (Lysinibacillus fusiformis strain VASB14/WL and Bacillus cereus strain VASB1/TS) of Avicennia marina Vierh (Forsk.) from the West Coast of India with the potential to degrade plastic (polythene). The present book attempted to address the bioremediation scenario of plastic waste (including micro plastic) using microbes with bacteria in particular. Various strategies used to tackle with the plastic waste were highlighted with case studies of plastic waste management, including in vitro, in situ and ex situ with a special reference to biodegradation technology. After the biodegradation of the plastic using microbes, the generated plastic (polythene) degradation products (PE-DPs) were also documented using GC-MS technique followed by their deleterious effect on both animal and plant systems. The book also enhances the awareness of the plastic-free society and also suggests some alternative materials to be used instead of plastic. Lastly, the book suggests/recommends the strategies to be followed by the lawmakers in the government organizations/non-government organizations/social organizations to frame the regulations and guidelines to implement at mass level to reduce the generation of plastic waste.

This book coherently presents advances in design principles, processes, and methods in healthcare product design. It captures the implications of technological advances on designing healthcare products especially when market and societal needs pull each other in opposite directions. The contents focus on innovative design thinking processes and methods in developing healthcare products, applications of digital technologies in healthcare product design, amalgamation of artificial intelligence and design thinking for healthcare product design and quality, sustainability, and regulatory aspects in the design process. This book is a useful reference for those in the industry and academia.

Introduces both optical microscopy and medical imaging with an emphasis on recurring themes such as resolution and contrast to reinforce understanding. Includes many illustrations and boxed material that give more detailed explanations. Features hands-on activities and experiments. Provides end-of-chapter problems for self-study. Offers supplementary online materials including a solutions manual.