Robots have come a long way thanks to advances in sensing and computer vision technologies and can be found today in healthcare, medicine and industry. Researchers have been looking at providing them with senses such as the ability to see, smell, hear and perceive touch in order to mimic and interact with humans and their surrounding environments. Topics covered in this edited book include various types of sensors used in robotics, sensing schemes (e-skin, tactile skin, e-nose, neuromorphic vision and touch), sensing technologies and their applications including healthcare, prosthetics, robotics and wearables. This book will appeal to researchers, scientists, engineers, and graduate and advanced students working in robotics, sensor technologies and electronics, and their applications in robotics, haptics, prosthetics, wearable and interactive systems, cognitive engineering, neuro-engineering, computational neuroscience, medicine and healthcare technologies.

The research areas as well as the knowledge gained for the practical use of robots are growing and expanding beyond manufacturing and industrial automation, making inroads in sectors such as health care and terrain sensing, as well as general assistive systems working in close interaction with humans. In a situation like this, it is necessary for future robot systems to become less stiff and more specialized by taking inspiration from the mechanical compliance and versatility found in natural materials and organisms. At present, a new discipline is emerging in this area, called "Soft Robotics". It particularly challenges the traditional thinking of engineers, as the confluence of technologies, ranging from new materials, sensors, actuators and production techniques to new design tools, will make it possible to create new systems whose structures are almost completely made of soft materials, which bring about entirely new functions and behaviors, similar in many ways to natural systems. These Proceedings focus on four main topics: * Soft Actuators and Control * Soft Interactions * Soft Robot Assistants: Potential and Challenges * Human-centered "Soft Robotics".

This book offers an impressive collection of contributions on the epistemology of international biolaw and its applications, both in the legal and ethical fields. Bringing together works by some of the world's most prominent experts on biolaw and bioethics, it constitutes a paradigmatic text in its field. In addition to exploring various ideologies and philosophies, including European, American and Mediterranean biolaw traditions, it addresses controversial topics straight from today's headlines, such as genetic editing, the dual-use dilemma, and neurocognitive enhancement. The book encourages readers to think objectively and impartially in order to resolve the ethical and juridical dilemmas that stem from biotechnological empowerment and biomedical techniques. Accordingly, it offers a valuable resource for courses on biolaw, law, bioethics, and biomedical research, as well as courses that discuss law and the biosciences at different professional levels, e.g. in the courts, biomedical industry, pharmacological companies and the public space in general.

This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. * Takes a transformative, "cyberphysical" approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; * Presents a "physically-aware" system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; * Enables readers to simplify the structure of biochips, while facilitating the "general-purpose" use of digital microfluidic biochips for a wider range of applications.

Describes how nanomaterial functionalization is being used to create more effective sensors. Discusses various synthesis procedures, characterization techniques, and which nanomaterials should be used for sensing applications. Provides an in-depth look into oxide nanostructures, carbon nanostructures, and 2D material fabrication. Explores the challenges of using nanoscale sensors for large-scale industrial applications.

The book set develops a bridge between physiologic mechanisms and diagnostic human engineering. While the first volume is focused on the interface between physiologic mechanisms and the resultant biosignals, this second volume is devoted to the interface between biosignals and biomedical sensors. That is, in the first volume, the physiologic mechanisms determining biosignals are described from the basic cellular level up to their advanced mutual coordination level. This second volume, considers the genesis of acoustic and optic biosignals and the associated sensing technology from a strategic point of view. As a novelty, this book discusses heterogeneous biosignals within a common frame. This frame comprises both the biosignal formation path from the biosignal source at the physiological level to biosignal propagation in the body, and the biosignal sensing path from the biosignal transmission in the sensor applied on the body up to its conversion to a, usually electric, signal. Some biosignals arise in the course of the body's vital functions while others map these functions that convey physiological data to an observer. It is highly instructive how sound and light beams interact with biological tissues, yielding acoustic and optic biosignals, respectively. Discussed phenomena teach a lot about the physics of sound and physics of light (as engineering sciences), and, on the other hand, biology and physiology (as live sciences). The highly interdisciplinary nature of biosignals and biomedical sensors is obviously a challenge. However, it is a rewarding challenge after it has been coped with in a strategic way, as offered here. The book is intended to have the presence to answer intriguing "Aha!" questions.

Biomedical signals provide unprecedented insight into abnormal or anomalous neurological conditions. The computer-aided diagnosis (CAD) system plays a key role in detecting neurological abnormalities and improving diagnosis and treatment consistency in medicine. This book covers different aspects of biomedical signals-based systems used in the automatic detection/identification of neurological disorders. Several biomedical signals are introduced and analyzed, including electroencephalogram (EEG), electrocardiogram (ECG), heart rate (HR), magnetoencephalogram (MEG), and electromyogram (EMG). It explains the role of the CAD system in processing biomedical signals and the application to neurological disorder diagnosis. The book provides the basics of biomedical signal processing, optimization methods, and machine learning/deep learning techniques used in designing CAD systems for neurological disorders.

Electromagnetic waves have long been used in medical settings for diagnostic purposes, such as for the detection of cancerous tissues, stroke events or cardiovascular risk, as the behaviour of the waves upon meeting their target gives pertinent information for diagnostic and imaging purposes. This edited book presents advances in the use of electromagnetic waves and antennas in healthcare settings, both as diagnostic tools (such as radar-based imaging, holographic microwave imaging, thermoacoustic imaging systems), and therapeutic interventions (such as microwave ablation therapies for cancer). Written by an international team of biomedical engineering researchers, it discusses all aspects related to the design and modelling of electromagnetic imaging techniques, electromagnetic devices, wireless implants, wearable systems and wireless sensor networks and in vitro and in vivo testing. Design issues for wearable antennas, wearable sensors, magnetic coils and coil array issues are explored and biomedical applications such as cancer detection, stoke event detection, GI diagnostics, and cardiovascular risk prediction are discussed. The book also explores scattering problems of electromagnetic waves between different tissues, and how these complex scattering problems can be resolved. This book will be of interest to researchers and engineers in the electromagnetic wave community, those in antenna research, biomedical engineering and related fields.

Plastic is one of the widely used polymers around the globe since its discovery. It is highly impossible to think the ease of life without the aid of plastic. Every year billion tons of plastic waste gets accumulated in the environment and leads to death of both marine and terrestrial animals. Plastic is very durable and needs around 1000 years to degrade under the natural environment. The present book illustrates the importance and significance of the bioremediation to tackle the problem of plastic waste. Previously, we have reported elite rhizobacterial isolates (Lysinibacillus fusiformis strain VASB14/WL and Bacillus cereus strain VASB1/TS) of Avicennia marina Vierh (Forsk.) from the West Coast of India with the potential to degrade plastic (polythene). The present book attempted to address the bioremediation scenario of plastic waste (including micro plastic) using microbes with bacteria in particular. Various strategies used to tackle with the plastic waste were highlighted with case studies of plastic waste management, including in vitro, in situ and ex situ with a special reference to biodegradation technology. After the biodegradation of the plastic using microbes, the generated plastic (polythene) degradation products (PE-DPs) were also documented using GC-MS technique followed by their deleterious effect on both animal and plant systems. The book also enhances the awareness of the plastic-free society and also suggests some alternative materials to be used instead of plastic. Lastly, the book suggests/recommends the strategies to be followed by the lawmakers in the government organizations/non-government organizations/social organizations to frame the regulations and guidelines to implement at mass level to reduce the generation of plastic waste.

The book provides an overview of bio-manufacturing techniques for the production, purification, characterization and modification of chito/chitin oligosaccharides and their monomers. In addition, it explores potential applications in the food, biomedical and agricultural industry on the basis of their bioactivities and biomaterial properties. Lastly, it shares a range of cutting-edge insights to help solve problems in industrial processes and promote further academic investigation. Given its scope, it offers a valuable resource for researchers and graduate students in the fields of bioengineering, food science, biochemistry, etc.

This book explores a sampling of the most powerful and enterprising efforts to achieve biotechnological goals by means of various interdisciplinary approaches. From the fabrication of extremely small units to achieve specific objectives through nano-bio-technology, to devices with artificial intelligence, gene therapy for cerebrovascular anomalies, biodegradable plastics, the use of phyto-stem cells in cosmetology, CarT cell immune therapy, targeted therapies for cancer, 3D printed bones developed by the University of Wollongong in Australia, the sickle cell chip developed by IIT Bombay, and innovative sustainable energy solutions, the book includes a colorful spectrum of reviews on current and future biotech products. Gathering contributions by an international team of researchers, this book offers its audience, and particularly younger readers, revealing information on current and upcoming smart technologies.

This volume covers current research in the usage of magnetic nanoparticles for drug delivery. It discusses synthesis methods, stabilizers used for surface coating on MNPs, and potential target ligands which can be used to ferry payloads to the targeted disease region. It also highlights the factors affecting delivery efficiency and toxicity, as well as the different routes of administration. The content also focus on the use of these carriers for gene therapy and to target brain tumors. This volume will be of interest to researchers working on drug discovery and delivery platforms.

Despite major advances in healthcare over the past century, the successful treatment of cancer has remained a significant challenge, and cancers are the second leading cause of death worldwide behind cardiovascular disease. Early detection and survival are important issues to control cancer. The development of quantitative methods and computer technology has facilitated the formation of new models in medical and biological sciences. The application of mathematical modelling in solving many real-world problems in medicine and biology has yielded fruitful results. In spite of advancements in instrumentations technology and biomedical equipment, it is not always possible to perform experiments in medicine and biology for various reasons. Thus, mathematical modelling and simulation are viewed as viable alternatives in such situations, and are discussed in this book. The conventional diagnostic techniques of cancer are not always effective as they rely on the physical and morphological appearance of the tumour. Early stage prediction and diagnosis is very difficult with conventional techniques. It is well known that cancers are involved in genome level changes. As of now, the prognosis of various types of cancer depends upon findings related to the data generated through different experiments. Several machine learning techniques exist in analysing the data of expressed genes; however, the recent results related with deep learning algorithms are more accurate and accommodative, as they are effective in selecting and classifying informative genes. This book explores the probabilistic computational deep learning model for cancer classification and prediction.

The volume is comprehensively covers emerging technologies for health care, various aspects of biomedical research towards understanding of pathophysiology of the diseases, advances in improvement in diagnostic procedures and therapeutic tools, the fundamental role of biomedical research in the development of new medicinal products

This book examines the basic cellular and molecular mechanisms associated with aging. It comprehensively describes the genetic, epigenetic, biochemical and metabolic regulation of aging, as well as some important age-related diseases. Divided into two major sections, it takes readers through the various aspects of aging in a story-like manner and suggests various interventions for healthy aging, such as dietary restriction, regular exercise, nutrition and maintaining a balanced and a non-stressful lifestyle. It describes the implications of aging on the nervous system, metabolism, immunity and stem cells as well as care for the elderly. The book is an ideal companion for both new and established researchers in the field and is also useful for educators, clinicians and policy makers.

This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

This book reviews the latest technological developments of bioengineering approaches in cell and tissue research. It is meant to have life and spirit, and to become a pioneer in technology and sciences, especially the life science. The chapters are written by excellent scientists on advanced, frontier technology and address scientific questions that need considerable thinking in terms of engineering. The aims are to provide the readers, including students, faculty, and all scientists working in academia and industry, new information on bioengineering in cell and tissue research to enhance their understanding and innovation.

This book will give insight into emerging semiconductor devices from their applications in electronic circuits, which are the backbone of electronic equipment. It provides desired exposure to the ever-growing field of low-power electronic devices and their applications in nanoscale devices, memory design, and biosensing applications. Tunneling Field Effect Transistors: Design, Modeling, and Applications bring researchers and engineers from various disciplines of the VLSI domain together to tackle the emerging challenges in the field of nanoelectronics and applications of advanced low-power devices. The book begins by discussing the challenges of conventional CMOS technology from the perspective of low-power applications. The book also reviews the basic science and developments of subthreshold swing technology and recent advancements in the field. The authors discuss the impact of semiconductor materials and architecture designs on TFET devices and the performance and usage of FET devices in various domains like nanoelectronics, Memory Devices, and biosensing applications. The authors also cover a variety of FET devices, such as MOSFETs and TFETs, with various structures based on the tunneling transport phenomenon. The contents of the book have been designed and arranged in such a way that Electrical Engineering students, researchers in the field of nanodevices and device-circuit codesign, as well as industry professionals working in the domain of semiconductor devices, will find the material useful and easy to follow.

This book describes the range of technologies that have been developed for diagnosing and assessing Parkinson's disease patients. Also presenting the latest studies providing insights into the changes to the neural system in Parkinson's disease, it is a valuable resource for neurologists, general practitioners and nurses. Further, the book highlights areas that require more research, and as such will appeal to researchers, biomedical engineers and clinicians.

This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices. The up-to-date book provides an in-depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications. Biophysics and thermodynamics, supported by mathematics, are the locomotive by which the drug transportation and the targeting processes will be achieved under the light of the modern pharmacotherapy. They are considered as scientific tools that promote the understanding of physicochemical and thermotropic functionality and behavior of artificial cell membranes and structures like nanoparticulate systems. Therefore, this book focusses on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems, and it correlates their physicochemical, biophysical and thermodynamical behaviour with those of a living organism. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.

This book describes the basic physical principles of techniques to generate and ultrashort pulse lasers and applications to ultrafast spectroscopy of various materials covering chemical molecular compounds, solid-state materials, exotic novel materials including topological materials, biological molecules and bio- and synthetic polymers. It introduces non-linear optics which provides the basics of generation and measurement of pulses and application examples of ultrafast spectroscopy to solid state physics. Also it provide not only material properties but also material processing procedures. The book describes also details of the world shortest visible laser and DUV lasers developed by the author's group. It is composed of the following 12 Sections: The special features of this book is that it is written by a single author with a few collaborators in a systematic way. Hence it provides a comprehensive and systematic description of the research field of ultrashort pulse lasers and ultrafast spectroscopy. Generation of ultrashort pulses in deep ultraviolet to near infrared Generation of ultrashort pulses in terahertz Carrier envelope phase (CEP) Simple NLO processes with a few colors Multi-color involved NLO processes Multi-color ultrashort pulse generation NLO materials NLO processes in time-resolved spectroscopy Low dimension materials Conductors and superconductors Chemical reactions and material processing Photobiological reactions

This book presents a compilation of state-of-the-art work on biomedical and cyber-physical systems in connection with the Internet of Things, and successfully blends theory and practice. The book covers the studies belonging to Biomedical and Cyber-physical System, so it is a unique effort by the research experts, who are divulging in the domain deeply. The book is very easy for the audience, who are doing study in the Biomedical and Cyber-physical System; it helps to read some real-time scenarios from where the reader in general gets many sparking ideas to convert it into the research problems in their studies. This book is of use to solve down the problems of graduate, postgraduate, doctoral industry executives, who are involving in the cutting-edge work of Internet of Things with Biomedical or Cyber-physical System, with the help of real-time solutions, given in the formation of chapters by subject's experts.The key uses of this book are in the area of Internet of Things in connection with Cyber-physical System as well as Biomedical domain.

The explosion of technology in healthcare in recent years has rapidly changed the healthcare sector. Technologies such as artificial intelligence and machine learning along with the integration of the Internet of Medical Things (IoMT) have evolved to tackle the need for remote healthcare systems, augmenting them in a self-sustainable way. This new volume explores computational tactics as applied to the development of biomedical applications, using artificial intelligence, machine learning, signal analysis, computer-aided design, robotics and automation, biomedical imaging, telemedicine, and other technologies. The book aims to provide a solid framework to provide the modern class of medical gearheads with information on the innovative applications of computational mechanisms for improving and expediting patient-friendly automation in healthcare. The volume provides an overview of the advancements in modern technology for diagnosing major life-threatening diseases, including using photonic MEMS sensors, biomedical signal processing, 1D photonic crystal-based distributed Bragg reflectors (DBRs), and biosensor chips used to detect foreign bodies, such as cancer cells, or infected stages of blood cells for quick medical diagnosis. The book discusses employing predictive analysis using AI, ML, and DL for tracking diseases, predicting their progress, and designing tactics as applied to heart disease, coronavirus, and many other ailments. It looks at various machine learning methods, grouping and association rules, vector machine assistance, and evolutionary algorithms. Also discussed is the evolution and implementation of information and communication technologies in healthcare delivery, which hold enormous promise for patients, providers, and payers in future healthcare systems. Other topics include using drones in health centers, such as for drug distribution and other purposes; using powerful artificial intelligence algorithms that can reveal clinically significant information hidden in vast amounts of data; and more. Computational Health Informatics for Biomedical Applications explores the many important smart technologies that can make healthcare delivery and monitoring faster, more efficient, and less invasive. It will be a valuable resource for those at the forefront of designing and employing advanced smart technologies for improved healthcare services.