In a normal physiological state, several bacteria are present in the human gut that is essential to maintain the normal to healthy gastrointestinal function. Disturbances in this "normal flora" lead to gut inflammation and infection. This volume explores the potential of probiotics, the healthy bacteria, to manage gut-related diseases including gastrointestinal cancers, ulcerative colitis, H. pylori infections, and diarrhea; vaginosis; oral health; airway inflammation; and atopic dermatitis. The concept of designer probiotics, edible vaccines and future scope of research in the field is also presented. The animal models used for studying the benefits of probiotics in gut inflammation are described for beginners.

This handbook adopts a distinctively global and intersectional approach to gender and migration, as social class, race and ethnicity shape the process of migration in its multiple dimensions. A large range of topics exploring gender, sexuality and migration are presented, including feminist migration research, care, family, emotional labour, brain drain and gender, parenting, gendered geographies of power, modern slavery, women and refugee law, masculinities, and more. Scholars from North and South America, Europe, Asia, and Oceania delve into institutional, normative, and day-to-day practices conditioning migrants rights, opportunities and life chances based on material from around the world. This handbook will be of great interest to students and scholars across a range of disciplines, including Women's and Gender Studies, Sociology, Sexuality Studies, Migration Studies, Politics, Social Policy, Public Policy, and Area Studies.

Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.

Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems.

This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances.

This edited book details the plant-assisted remediation methods, which involves the interaction of plant roots with associated rhizospheric microorganisms for the remediation of soil and water contaminated with high levels of heavy metals, pesticides, radionuclides, agricultural by-products, municipal wastes, industrial solvents, petroleum hydrocarbons, organic compounds, and various other contaminants. Each chapter highlights and compares the beneficial and economical alternatives of phytoremediation to currently practiced soil, water, and air removal. This book covers state-of-the-art approaches in phytoremediation contributed by leading and eminent scientists from across the world. Phytoremediation approaches for environmental sustainability dealing the readers with a cutting-edge of multidisciplinary understanding in the principal and practical approaches of phytoremediation from laboratory research to field application. This book is of interest to researchers, teachers, environmental scientists, environmental engineers, environmentalists, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of environmental microbiology, biotechnology, eco-toxicology, environmental remediation, waste management, and environmental sciences as well as the general audience.

This book provides a comprehensive overview of the current knowledge on the fate and interaction of pharmaceuticals in soil-crop systems. It addresses the principles of their transport, uptake and metabolism and reviews methodologies for their analytical determination. It also discusses ecotoxicological effects arising from their presence and highlights bioremediation approaches for their removal. The use of treated wastewater to irrigate crops is becoming more widespread in regions where freshwater is limited. This practice conserves freshwater resources and contributes to nutrient recycling. However, concerns remain regarding the safety of irrigation with treated wastewater since it contains residues of pharmaceuticals that have survived treatment, which means that soil and fauna are potentially exposed to these xenobiotics. Various pathways govern the fate of pharmaceuticals in crop-soil systems, including soil degradation; formation of non-extractable residues; uptake by soil-dwelling organisms (e.g. earthworms); and uptake, transport, and metabolism in agricultural crops. Investigations into these aspects have only recently been initiated, and there is still a long way to go before a meaningful assessment of the impact of wastewater has been completed.

Since the launch of Telemedicine Technologies (Wiley, 2010), the technologies surrounding telemedicine have changed immeasurably, particularly with the emerging trends of Internet-of-Things (IoT), digital/e-Health, and wearable, smart and assistive technologies. This second edition overhauls and expands on the original text to reflect the technical advances of the last decade. It covers applications from traditional healthcare services to remote patient monitoring and recovery, to alternative medicine and general health assessment for maintaining optimal health. This welcome update brings together a broad range of topics demonstrating how information and wireless technologies can be used in healthcare.

This book highlights the importance of molecular genomics, molecular biology techniques to sort out the problems faced by industrialist who operates wastewater treatment plant with the ever-increasing number of environmental pollutants. Describes application of different Omic tools in Wastewater treatment plants (WWTPs) Describes the role of microorganisms in WWTPs Points out the reuse of treated wastewater through emerging technologies. Includes the recovery of resources from wastewater Emphasizes on cutting edge molecular tools This book targets engineers, scientists and managers who require an excellent introduction and basic knowledge to the principles of molecular biology or molecular genomics in the area of wastewater treatment. Different professionals working or interested in the Environmental Microbiology or Bioremediation or Environmental Genomics field. Students on Environmental Biotechnology/Microbiology.

Microbial biosurfactant compounds are a group of structurally diverse molecules produced by microorganisms, and are mainly categorized according to their chemical structure. The diversity of microbial biosurfactants makes them versatile and means that they offer a range of capabilities, while at the same time being economically sustainable. As such, they have potential applications in environmental processes, as well as in food, biomedicine and other industries. This book discusses innovative approaches and cutting-edge research that utilize the various properties of biosurfactants. Drawing on research from around the globe, it provides an up-to-date review of biosurfactant applications and their importance in fields such as medicine, gene therapy, immunotherapy, antimicrobial bioremediation and agriculture. It also discusses their anti-adhesive properties. The book will appeal to academics and researchers in the field of microbiology, as well as policymakers. It also serves as additional reading material for undergraduate and graduate students of agriculture, ecology, soil science, and environmental sciences.

This book presents recent developments in the field of environmental biotechnology. Three major forces are currently driving this discipline: the exploration of microbial diversity by genetic and genomic tools, the ongoing progress in the modelling of various transient phenomena, and environmental biotechnology. This book provides a state-of-art-overview of developments in the field of environmental biotechnology concerning exploration, implementation, modelling, economic development and safety. It comprises selected, peer-reviewed papers that were presented at the European Symposium on Environmental Biotechnology (ESEB) 2004, held in Oostende, Belgium, April 2004.

An easy-to-use reference source on the applications and management of biotechnology!
The Concise Encyclopedia of Bioresource Technology is a unique resource for state-of-the-art research findings on biotechnological innovations and their potential for commercial exploitation. This comprehensive reference gives you immediate access to information on the application of bioresource technology as it relates to industrial, food, and environmental biotechnology. Practitioners, academics, and researchers representing a wide range of disciplines examine vital issues including the production and applications of microbial enzymes and organic acids, fermentation, wastewater treatment, and air pollution.
The Concise Encyclopedia of Bioresource Technology will bring you up-to-date on advances in the applications and management of bioprocesses, biomass, bioenergy, biological waste treatment, biotransformations, and conversion and production technologies. This vital information has been organizedin an easy-to-use format that lets you become familiar with highlights of the most relevant topics and includes photographs, figures, and tables. Issues addressed in the book include: agro-industrial residues for bioprocesses solid-state fermentation for bioconversion of biomass alcoholic fermentation food grade yeast production treatment of industrial effluents anaerobic animal waste environments reactors for wastewater treatment and much more! The Concise Encyclopedia of Bioresource Technology is a vital resource for practitioners, researchers, and academics working in the areas of biotechnology, chemical engineering, resource, energy and conservation sciences, process technology, appliedmicrobiology, and farm and industrial waste technology.

This edited collection explores forms of multi-religious cohabitation as well as the spatial arrangements that underpin and shape them through sixteen chapters that range across disciplines, historical periods, and global geographies. Focusing on interactions between different religious groups and traditions, the authors conceptualize three types of spatial arrangements and explore how they operate ad geographies of encounter; i.e., multi-religious places, multi-religious cities, and multi-religious landscapes. With perspectives from anthropologists, historians, sociologists, and geographers, the book demonstrates the multiple ways in which geographies of interreligious encounters and forms of multi-religious cohabitation have changed throughout history due to their embeddedness id different frameworks of political organization, shifting religious ideologies, and changing forms of human mobility.

History will mark the twenty-first century as the dawn of the age of precise genetic manipulation. Breakthroughs in genome editing are poised to enable humankind to fundamentally transform life on Earth. Those familiar with genome editing understand its potential to revolutionize civilization in ways that surpass the impact of the discovery of electricity and the development of gunpowder, the atomic bomb, or the Internet. Significant questions regarding how society should promote or hinder genome editing loom large in the horizon. And it is up to humans to decide the fate of this powerful technology. Rewriting Nature is a compelling, thought-provoking interdisciplinary exploration of the law, science, and policy of genome editing. The book guides readers through complex legal, scientific, ethical, political, economic, and social issues concerning this emerging technology, and challenges the conventional false dichotomy often associated with science and law, which contributes to a growing divide between both fields.

History will mark the twenty-first century as the dawn of the age of precise genetic manipulation. Breakthroughs in genome editing are poised to enable humankind to fundamentally transform life on Earth. Those familiar with genome editing understand its potential to revolutionize civilization in ways that surpass the impact of the discovery of electricity and the development of gunpowder, the atomic bomb, or the Internet. Significant questions regarding how society should promote or hinder genome editing loom large in the horizon. And it is up to humans to decide the fate of this powerful technology. Rewriting Nature is a compelling, thought-provoking interdisciplinary exploration of the law, science, and policy of genome editing. The book guides readers through complex legal, scientific, ethical, political, economic, and social issues concerning this emerging technology, and challenges the conventional false dichotomy often associated with science and law, which contributes to a growing divide between both fields.

This book caters to the need of researchers working in the ever-evolving field of agricultural biotechnology. It discusses and provides in-depth information about latest advancements happening in this field. The book discusses evolution of plant tissue culture techniques, development of doubled haploids technology, role of recombinant-DNA technology in crop improvement. It also provides an insight into the global status of genetically modified crops, use of RNAi technology and mi-RNAs in plant improvement. Chapters are also dedicated for different branches of 'omics' science including genomics, bioinformatics, proteomics, metabolomics and phenomics along with the use of molecular markers in tagging and mapping of various genes/QTLs of agronomic importance. This book also covers the role of enzymes and microbes in agriculture in productivity enhancement. It is of interest to teachers, researchers of biotechnology and agriculture scientists. Also the book serves as additional reading material for undergraduate and postgraduate students of biotechnology, agriculture, horticulture, forestry, ecology, soil science, and environmental sciences. National and international biotechnologists and agricultural scientists will also find this to be a useful read.

This book is an inclusive coverage of advances in aquaculture health management. It offers latest updates as well as explains the novel concepts and issues related to aquatic animal health management. To support the understanding of the concepts, there is extensive use of illustrations. Chapters emphasize on the state of art techniques and hold great promise for the sustainable development of aquaculture. This book is of interest to teachers, researchers, aquatic biologists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of aquatic sciences, marine sciences, biotechnology, ecology, and environmental sciences. National and international aquatic scientists, policy makers will also find this to be a useful read.

Biological control has become an attractive alternative strategy for the control of plant diseases to reduce the excessive use of agrochemicals and its health hazards. But a significant gap still exists between basic research involving the discovery of a biocontrol agent and its development and implementation under commercial conditions. Because BCAs (unlike chemical a.m.) need to establish, colonize, survive and perform their metabolic activity to control diseases. In order to move a biocontrol agent from the laboratory to the market place requires many different disciplines and people with a variety of expertise. Research can stimulate the development of commercial biocontrol agents. Chapter 16 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book focuses on biogas production by anaerobic digestion, which is the most popular bioenergy technology of today. Using anaerobic digestion for the production of biogas is a sustainable approach that simultaneously also allows the treatment of organic waste. The energy contained in the substrate is released in the form of biogas, which can be employed as a renewable fuel in diverse industrial sectors. Although biogas generation is considered an established process, it continues to evolve, e.g. by incorporating modifications and improvements to increase its efficiency and its downstream applications. The chapters of this book review the progress made related to feedstock, system configuration and operational conditions. It also addresses microbial pathways utilized, as well as storage, transportation and usage of biogas. This book is an up-to-date resource for scientists and students working on improving biogas production.

Value Addition in Food Products and Processing using Enzyme Technology offers an updated review regarding the potential impact of new enzymes and enzyme technology on the food sector. The book brings together novel sources and technologies regarding enzymes in value added food development, food production, food processing, food preservation, food engineering and food biotechnology. It will be extremely useful for different types of readers, including food scientists, academic and food biotechnologists, but will also be ideal for students studying food-related courses. This book includes concise and up-to-date research information from multiple independent scientific papers from around the world. This is a essential, multidisciplinary text for research and development professionals, research scientists, and academics in food, biotechnology, and agriculture industries. It addresses safety issues and includes the sources, screening, immobilization and application of food-grade enzymes in food.

This book provides a comprehensive account of past, present and future of the biomass based biorefineries. It is an all-inclusive and insightful compilation of recent advancements in the technology and methods used for conversion of biomass to bioenergy and other useful biochemicals. The book also focuses on the limitations of existing technologies and provides the future prospects, as well as discusses socio-economic impact of biomass based biorefineries. This book assists researchers in the area of lignocellulosic biorefineries and can be used by the students, scientist and academician as an advanced reference textbook.

This open access book gathers authoritative contributions concerning multiscale problems in biomechanics, geomechanics, materials science and tribology. It is written in memory of Sergey Grigorievich Psakhie to feature various aspects of his multifaceted research interests, ranging from theoretical physics, computer modeling of materials and material characterization at the atomic scale, to applications in space industry, medicine and geotectonics, and including organizational, psychological and philosophical aspects of scientific research and teaching as well. This book covers new advances relating to orthopedic implants, concerning the physiological, tribological and materials aspects of their behavior; medical and geological applications of permeable fluid-saturated materials; earthquake dynamics together with aspects relating to their managed and gentle release; lubrication, wear and material transfer in natural and artificial joints; material research in manufacturing processes; hard-soft matter interaction, including adhesive and capillary effects; using nanostructures for influencing living cells and for cancer treatment; manufacturing of surfaces with desired properties; self-organization of hierarchical structures during plastic deformation and thermal treatment; mechanics of composites and coatings; and many more. Covering established knowledge as well as new models and methods, this book provides readers with a comprehensive overview of the field, yet also with extensive details on each single topic.

This book gives a comprehensive overview on the various aspects of Trichoderma, a filamentous fungus ubiquitously present in soil. Topics addressed are the biology, diversity, taxonomy, ecology, biotechnology and cultivation of Trichoderma, to just name a few. Basic as well as applied aspects are covered and a special focus is given on use of Trichoderma in agriculture and beyond. Trichoderma species are widely distributed throughout the world in soil, rotting plant material, and wood. Although they are often considered as a contaminants, Trichoderma species are also known for their ability to act as biocontrol agents against various plant pathogens and plant diseases, and also as biostimulants promoting plant growth. The contents of this book will be of particular interest to, agricultural scientists, biotechnologists, plant pathologists, mycologists, and microbiologists, students, extension workers, policy makers and other stakeholders.

This volume provides clear and direct protocols to implement automated Design-Build-Test-Learn (DBTL) into synthetic biology research. Chapters detail techniques to model and simulate biological systems, redesign biological systems, setting up of an automated biolaboratory, step-by-step guide on how to perform computer aided design, RNA sequencing, microfluidics -using bacterial cell free extracts, live mammalian cells, computational and experimental procedures, metabolic burden, computational techniques to predict such burden from models, and how DNA parts can be engineered in mammalian cells to sense, and respond to, and intracellular signals in general. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Synthetic Gene Circuits: Methods and Protocols aims to ensure successful results in the further study of this vital field.

This book reviews alternative and renewable energy resources in order to pave the way for a more sustainable production in the future. A multi-disciplinary team of authors provides a comprehensive overview of current technologies and future trends, including solar technologies, wind energy, hydropower, microbial electrochemical systems and various biomass sources for biofuel production. In addition, the book focuses on solutions for developing countries. Conventional energy sources are finite, and estimates suggest that they will be exhausted within a few decades. Finding a solution to this problem is a global challenge, and developing countries in particular are still highly dependent on fossil fuels due to their rapidly growing populations accompanied by a huge growth in primary energy consumption. Moreover, the most common conventional energy sources (coal and petroleum) are non-sustainable since their combustion exponentially increases greenhouse gas emissions. As such, there is a pressing need for clean energy based on alternative or renewable resources, not only to ensure energy supplies at an affordable price but also to protect the environment.