Designed for advanced undergraduate and graduate students, this textbook explores both the psychological and biological influences on the development of behavior, using data from both animal and human subjects to support principles and hypotheses. The arrangement of the book is both chronological and topical, commencing with embryonic behavior and the influence of prenatal exposure to hormones and teratological agents and moving on to postnatal maternal influences and early stimulation. Play, learning and memory, and finally weaning and puberty complete this volume.
This comprehensive work provides a history of this subdiscipline from the earliest research of Wilhelm Preyer in 1885 to the most recent findings on the psychobiology of behavioral development.

This detailed study of the different rates of growth of parts of the body relative to the body as a whole represents Sir Julian Huxley's great contribution to analytical morphology, and it is still a basis for modern investigations in morphometrics and evolutionary biology. Huxley was the first to put the concept of relative growth - or allometry - upon a firm mathematical foundation, and since publication of this book in 1932, his work has been found to have greater implications than even he imagined. Problems of Relative Growth is at once a formulation of the basic principles of allometry and a survey of its many and various occurrences and applications. Examples are taken from such widely divergent areas as the development of the large claw in male fiddler-crabs, the size and number of points of deer antlers, heterogony in neuter social insects, the disproportionate growth of the human head from infancy to adulthood, and the formation of spiral shapes in certain mollusk shells and of the curved shape of the rhinoceros' horn. Starting from the fact of obvious disharmonic growth, Huxley formulates his first and fundamental law - that of the Constant Differential Growth Ratio. He then demonstrates that the distribution of growth potential occurs in an orderly and systematic way - that there are growth-gradients culminating in growth-centers. Other topics treated include multiplicative and accretionary kinds of growth, the role of hormones and mutations, and the relevance of the entire investigation to the problems of orthogenesis, recapitulation, vestigial organs, the existence of nonadaptive characters, physiological genetics, comparative physiology, and systematics. In theirintroduction to this unabridged facsimile republication of the original 1932 edition, Frederick B. Churchill and Richard E. Strauss place Huxley's work in the context of modern research in history and biology.

If you had a complete copy of a dinosaur's DNA and the genetic code, you still would not be able to make a dinosaur--or even determine what one looked like. Why? How do animals get their shape and how does shape evolve? In this important book, Nobel laureate Gerald M. Edelman challenges the notion that an understanding of the genetic code and of cell differentiation is sufficient to answer these questions. Rather, he argues, a trio of related issues must also be investigated--the development of form, the evolution of form, and the morphological and functional bases of behavior. "Topobiology" presents an introduction to molecular embryology and describes a comprehensive hypothesis to account for the evolution and development of animal form.

Developmental biology is seemingly well understood, with development widely accepted as being a series of programmed changes through which an egg turns into an adult organism, or a seed matures into a plant. However, the picture is much more complex than that: is it all genetically controlled or does environment have an influence? Is the final adult stage the target of development and everything else just a build-up to that point? Are developmental strategies the same in plants as in animals? How do we consider development in single-celled organisms? In this concise, engaging volume, Alessandro Minelli, a leading developmental biologist, addresses these key questions. Using familiar examples and easy-to-follow arguments, he offers fresh alternatives to a number of preconceptions and stereotypes, awakening the reader to the disparity of developmental phenomena across all main branches of the tree of life.

A fascinating and detailed examination of the evolution-and occasional devolution-of sexuality in microorganisms and more complex forms of life. Margulis and Sagan trace sex from its inauspicious beginnings in bacteria threatened by ultraviolet radiation to its intimate relation with the origin of mitotic division of nucleated cells. The origin of meiotic sex through cannibalism followed by centriole reproductive tardiness and the connection of cell symbiosis to sex and differentiation are explored. "The authors have not only given us a new and exiting scenario for the evolution of sex, but have also provided us with critical ways in which we can test their hypotheses. . . . This is a stimulating book that is sure to invoke criticism and discussion; I strongly recommend it."-Symbiosis "The book is well organized and well written, leading the reader from one thought to another almost effortlessly. Background information is presented to aid those of us who are not experts in this field, and a glossary is appended. The book could be used at all levels of study, from interested undergraduates in general biology though postdoctoral students of genetics and evolution. I recommend this thought-provoking book to you for both your enjoyment and your enlightenment."-Richard W. Cheney, Jr., Journal of College Science Teaching "This book, undoubtedly controversial, is a thoughtful and original contribution to an important aspect of cellular biology."-John Langridge

This volume consists of 82 classic and important contributions to the basic neurobiology of learning and memory. Included are historical articles as well as articles on developmental plasticity, hormones and memory, long-term potentiation, electrophysiology of memory, biochemistry of memory, morphology of memory, invertebrate models, and features of animal and human memory. This is a companion volume to Brain Theory Reprint Volume in which articles on mathematical models of memory are presented.

How did life start? Is the evolution of life describable by any physics-like laws? Stuart Kauffman's latest book offers an explanation-beyond what the laws of physics can explain-of the progression from a complex chemical environment to molecular reproduction, metabolism and to early protocells, and further evolution to what we recognize as life. Among the estimated one hundred billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere. Building on concepts from his work as a complex systems researcher at the Santa Fe Institute, Kauffman focuses in particular on the idea of cells constructing themselves and introduces concepts such as "constraint closure." Living systems are defined by the concept of "organization" which has not been focused on in enough in previous works. Cells are autopoetic systems that build themselves: they literally construct their own constraints on the release of energy into a few degrees of freedom that constitutes the very thermodynamic work by which they build their own self creating constraints. Living cells are "machines" that construct and assemble their own working parts. The emergence of such systems-the origin of life problem-was probably a spontaneous phase transition to self-reproduction in complex enough prebiotic systems. The resulting protocells were capable of Darwin's heritable variation, hence open-ended evolution by natural selection. Evolution propagates this burgeoning organization. Evolving living creatures, by existing, create new niches into which yet further new creatures can emerge. If life is abundant in the universe, this self-constructing, propagating, exploding diversity takes us beyond physics to biospheres everywhere.

This volume consists of 82 classic and important contributions to the basic neurobiology of learning and memory. Included are historical articles as well as articles on developmental plasticity, hormones and memory, long-term potentiation, electrophysiology of memory, biochemistry of memory, morphology of memory, invertebrate models, and features of animal and human memory. This is a companion volume to Brain Theory Reprint Volume in which articles on mathematical models of memory are presented.

From deep ocean trenches and the geographical poles to outer space, organisms can be found living in remarkably extreme conditions. This book provides a captivating account of these systems and their extraordinary inhabitants, 'extremophiles'. A diverse, multidisciplinary group of experts discuss responses and adaptations to change; biodiversity, bioenergetic processes, and biotic and abiotic interactions; polar environments; and life and habitability, including searching for biosignatures in the extraterrestrial environment. The editors emphasize that understanding these systems is important for increasing our knowledge and utilizing their potential, but this remains an understudied area. Given the threat to these environments and their biota caused by climate change and human impact, this timely book also addresses the urgency to document these systems. It will help graduate students and researchers in conservation, marine biology, evolutionary biology, environmental change and astrobiology better understand how life exists in these environments and their susceptibility or resilience to change.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

'Quite simply the best book about science and life that I have ever read' - Alice Roberts How does life begin? What drives a newly fertilized egg to keep dividing and growing until it becomes 40 trillion cells, a greater number than stars in the galaxy? How do these cells know how to make a human, from lips to heart to toes? How does your body build itself? Magdalena Zernicka-Goetz was pregnant at 42 when a routine genetic test came back with that dreaded word: abnormal. A quarter of sampled cells contained abnormalities and she was warned her baby had an increased risk of being miscarried or born with birth defects. Six months later she gave birth to a healthy baby boy and her research on mice embryos went on to prove that - as she had suspected - the embryo has an amazing and previously unknown ability to correct abnormal cells at an early stage of its development. The Dance of Life will take you inside the incredible world of life just as it begins and reveal the wonder of the earliest and most profound moments in how we become human. Through Magda's trailblazing research as a professor at Cambridge - where she has doubled the survival time of human embryos in the laboratory, and made the first artificial embryo-like structures from stem cells - you'll discover how early life is programmed to repair and organise itself, what this means for the future of pregnancy, and how we might one day solve IVF disorders, prevent miscarriages and learn more about the dance of life as it starts to take shape. The Dance of Life is a moving celebration of the balletic beauty of life's beginnings.

This book presents the latest developments in medicine and biology. Chapters include research on environmental risk factors for diabetic nephropathy; pre-endoscopic management of patients with hematemesis; the benefits of early diagnosis, halo fixation and/or ventral stabilization of dens-fractures in correspondence to age of the patient and fracture type; a discussion on how and to which extent heart rate variability (HRV) is acutely changed in diabetic ketoacidosis (DKA) or in hyperglycemic hyperosmolar syndrome (HHS); an evaluation of the anatomical, refractive and functional results of an innovative technique of deep anterior lamellar keratoplasty; the physical, emotional and quality of life aspects of patients with Cervical Dystonia; the current issues in medical literature regarding androgen use during menopause; an overall report on the benefits and limitations of human milk oligosaccharides (HMOs) mass spectrometry (MS) analysis; the classification methods of the X-ray cerebral angiograms; and the diagnosis and management of intraoperatively necrotizing fasciitis of the breast.

This book presents the latest developments in medicine and biology. Chapters include research on trends in the birth prevalence of boys with isolated hypospadias and undescended testis in Hungary during the last 50 years; alleviating premenstrual syndrome (PMS) symptoms using a natural factor; neutralization-enhancing RF antibodies; advances in the diagnosis, assessment, management and outcome of Takayasu's arteritis; macronutrients and premenstrual syndrome; pressurised intraperitoneal aerosol chemotherapy (PIPAC); the control of MAO expression; and what we know about iMAO.

Cell division is a highly co-ordinated process by which the living organisms grow, develop and reproduce. This book presents original research results on the leading edge of cell division research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum.

The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.

Why do the best-known examples of evolutionary change involve the alteration of one kind of animal into another very similar one, like the evolution of a bigger beak in a bird? Wouldn't it be much more interesting to understand how beaks originated? Most people would agree, but until recently we didn't know much about such origins. That is now changing, with the growth of the interdisciplinary field evo-devo, which deals with the relationship between how embryos develop in the short term and how they (and the adults they grow into) evolve in the long term. One of the key questions is: can the origins of structures such as beaks, eyes, and shells be explained within a Darwinian framework? The answer seems to be yes, but only by expanding that framework. This book discusses the required expansion, and the current state of play regarding our understanding of evolutionary and developmental origins.

Although books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.

Angiogenesis is the process by which new blood vessels are generated from preexisting vessels. It is vital for proper embryonic development, patterning of the vascular system, and wound healing. It is rate limiting in cancer progression, because the formation of new blood vessels is essential for growth and survival of tumors.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews the mechanisms of angiogenesis that operate in normal development and in diseases such as cancer. The contributors review the biology of endothelial cells, describing the specific roles of tip and stalk cells in vessel sprouting and lumen formation. They discuss the key angiogenic regulators (e.g., vascular endothelial growth factor VEGF]), as well as antiangiogenic agents including microRNAs, thrombospondins, and semaphorins. Therapeutic approaches that target pathological angiogenesis, such as the ongoing clinical trials of anti-VEGF drugs, are also covered. This volume, which includes discussions of other vascular dysfunctions (e.g., arteriovenous malformations) and comparisons between the blood vascular system and the lymphatic system, is a vital reference for developmental and cancer biologists, as well as anyone seeking to understand the biology and pathology of the vascular system.

Die phylogenetischen Beziehungen innerhalb des Stamms der Arthropoda sind noch immer nicht eindeutig geklart. Da Arthropoden eine geringe Anzahl homologer, serotonerger Neurone enthalten, koennen sie fur phylogenetische Vergleiche herangezogen werden. Die europaische Wanderheuschrecke Locusta migratoria dient als Modellorganismus fur die Klasse der Insekten. Martha Maria Kempf untersucht das Muster serotonerger Neurone in der ventralen Ganglienkette wahrend der Embryonalentwicklung von L. migratoria. Mithilfe immuncytochemischer Markierungen von Serotonin ermittelt sie, ab welchem Entwicklungsstadium im Embryo die posterioren Cluster serotonerger Neurone auftreten. Dies soll erste Hinweise liefern, wann diese Zellen in der Embryonalentwicklung entstehen und woher sie abstammen koennen. Die beschriebenen Ergebnisse und Erkenntnisse sind auch fur Evolutionsbiologen, Entwicklungsbiologen und Physiologen interessant, da der Neurotransmitter Serotonin im ganzen Tierreich in den verschiedensten Organsystemen weit verbreitet ist, einschliesslich der emotionalen Steuerung bei Saugetieren und Menschen.

A world-renowned paleontologist reveals groundbreaking science that trumps science fiction: how to grow a living dinosaur
Over a decade after "Jurassic Park," Jack Horner and his colleagues in molecular biology labs are in the process of building the technology to create a real dinosaur.
Based on new research in evolutionary developmental biology on how a few select cells grow to create arms, legs, eyes, and brains that function together, Jack Horner takes the science a step further in a plan to "reverse evolution" and reveals the awesome, even frightening, power being acquired to recreate the prehistoric past. The key is the dinosaur's genetic code that lives on in modern birds- even chickens. From cutting-edge biology labs to field digs underneath the Montana sun, "How to Build a Dinosaur" explains and enlightens an awesome new science.