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Books > Medicine > Clinical & internal medicine > Endocrinology

Mechanisms of Vascular Defects in Diabetes Mellitus (Hardcover, 1st ed. 2017): C C Kartha, Surya Ramachandran, Radhakrishna M.... Mechanisms of Vascular Defects in Diabetes Mellitus (Hardcover, 1st ed. 2017)
C C Kartha, Surya Ramachandran, Radhakrishna M. Pillai
R5,800 Discovery Miles 58 000 Ships in 10 - 15 working days

This book intends to bring together, a panel of renowned experts in the field of vascular biology and diabetology, to integrate the current understanding of the pathogenesis and pathophysiology of vascular diseases in diabetes mellitus. This attempt is significant given the increasing interest in this area as the prevalence of vascular diseases continues to escalate globally. Patients with diabetes are at a higher risk of structural and functional changes in all vessel walls of the human body. Vascular complications of diabetes are leading causes for both morbidity and mortality. In recent years, several articles have focused on advancing our knowledge on the profound effect of hyperglycemia and insulin resistance on building up vascular wall inflammation leading to endothelial dysfunction in patients with diabetes mellitus Other reports have elaborated on the various disorders, hyperglycemia can lead to, their therapies, adverse effects and complications. There are also studies that highlight the role of factors that induce vascular wall alterations in hyperglycemia. In this book, we attempt to discuss vascular disease progression in diabetes with a unique approach. We attempt to provide a complete perspective of the pathophysiology of vascular complications and then dissect each of the factors that play a key role in accelerating vascular wall alterations in diabetes. Each of these factors has been adversely implicated in the initiation and progression of disease to a large extent. In this collection for the first time all these factors would be described under a common canopy. Further, the text would emphasize on pathogenesis of micro vascular complications of diabetes, such as retinopathy, neuropathy and nephropathy. Pharmacological therapies for treating vascular dysfunction in diabetes mellitus would also be reviewed. This compendium hopefully would be an invaluable replacement to scores of literature on diabetic vascular disease and would be of great interest to clinicians, academicians, medical students and researchers. The book will be divided into seven sections, each emphasizing a common incentive to development of vascular disease in diabetes. Section I deals with pathophysiology of diabetic vascular disease, beginning with an update on the global burden of diabetes mellitus and its vascular complications. The pathophysiology and pathogenesis of diabetes associated macrovasculopathy, how hyperglycemia functions as an atherogenic factor, effects of hyperglycemia on smooth muscle accumulation in vascular lesions and genetic susceptibility for increased risk of vascular disease in diabetes will be discussed in the following chapters of this section. The next section (Section II) surveys the process of endothelial dysfunction under hyperglycaemia and hyperinsulinemia and their effects on angiogenesis, vascular remodeling and wound healing. A chapter is also dedicated to the endothelial progenitor cell population and its dysfunction during development of vascular complications in diabetes. Section III will highlight the molecular mechanisms underlying endothelial dysfunction, various pathways such as nitric oxide synthase pathway, oxidative stress pathway, renin - angiotensin system and increased vascular superoxide production in the initiation and progression of vascular disease in diabetes. This section also covers role of endothelin, monocyte derived cytokines, peroxynitrate and adipokines in macrovascular complications of diabetes. Metabolic factors such as advanced glycation end products, atherogenic dyslipoproteinaemia, and homocysteine will be reviewed in Section IV, whereas an overview of the hemostatic factors such as platelet dysfunction, hyperglycaemia induced thrombin formation and aberrant clot lysis will be dwelled upon in Section V.Section VI includes chapters on microvascular complications of diabetes which encompasses long term complications of diabetes affecting small blood vessels of the eye, kidneys and nervous system. The pathogenesis and mechanisms of these complications would be detailed here. The final section (Section VII) of the book will consider mechanism of action of drugs for treating endothelial dysfunction in diabetes mellitus which would elaborate on lipid regulating therapies such as statins, as well as other therapies such as ACE inhibitors, Angiotensin II receptors, insulin, metformin and their effects on enhancing vascular function in diabetes.

Endocrine Disrupting Chemicals - Occurrence, Exposures & Health Risks (Hardcover): Sabrina Johnston Endocrine Disrupting Chemicals - Occurrence, Exposures & Health Risks (Hardcover)
Sabrina Johnston
R4,376 Discovery Miles 43 760 Ships in 12 - 17 working days

Wide variety of pesticides and other synthetic chemicals may disrupt the normal function of the endocrine system, cause alteration and also attack the immune system of humans and wildlife at very low concentration levels. Chapter One of this book provides an overview of analytical methods, including sample preparation steps, chromatographic separation and detection of endocrine disrupting pesticides in a variety of food, environmental and biological matrices. Chapter Two studies endocrine disrupting compound (EDC) exposure from recycled wastewater compared to other water related risks in developed and developing nations. Chapter Three summarizes the role of EDCs on pregnancy and birth outcomes, included but not limited to fertility problems, premature birth, low birth weight, and miscarriage along with in-vitro, animal, and epidemiological studies. In the last chapter, the worst EDCs will be revealed and their related potential hazardous health risks to humans are discussed. Furthermore, suggestions to help the reader avoid such toxic chemicals are presented.

Endocrine Surgery - A South Asian Perspective (Paperback): Anand Kumar Mishra, Amit Agarwal, Rajeev Parameswaran, Kul Ranjan... Endocrine Surgery - A South Asian Perspective (Paperback)
Anand Kumar Mishra, Amit Agarwal, Rajeev Parameswaran, Kul Ranjan Singh
R4,383 Discovery Miles 43 830 Ships in 12 - 17 working days

This comprehensive book on Endocrine Surgery covers disorders of thyroid, parathyroid, adrenal glands along with neuroendocrine tumors of pancreas and gastrointestinal tract. It is a comprehensive, up-to-date treatise covering embryology, anatomy, etiology, clinical manifestations, diagnoses, and treatment modalities of surgical endocrine diseases. The authors explore the pertinent surgical endocrinology topics with a South Asian perspective. Color illustrations, flowcharts and tables make the topics lucid for professionals. This book provides the essential information surgeons require for evaluation and management of patients, both with straight forward, and complex endocrine problems. Key Features Focusses on concise yet comprehensive, up-to-date coverage of surgical endocrine diseases Discusses Robot Assisted Endocrine Surgery and explores its impact on healthcare finances Highlights the difference between practices used in western and resource limited countries by incorporating a South Asian perspective for region specific diseases.

ATTD 2011 Year Book - Advanced Technologies & Treatments for Diabetes 3e (Hardcover, New): M. Phillip ATTD 2011 Year Book - Advanced Technologies & Treatments for Diabetes 3e (Hardcover, New)
M. Phillip
R1,880 Discovery Miles 18 800 Ships in 12 - 17 working days

The traditional agents for controlling the levels of glucose in the blood remain important therapies but they have their downside from the point of view of tolerability and side effects. Moreover, they appear not to be able to counter the natural history deterioration of the disease in terms of the onset of diabetic-related complications.

Recent years have seen an influx of new treatment therapies and technologies aimed at achieving better glycaemic control for diabetic patients such as liraglutide (Novo Nordisk) and saxagliptin (BMS/Astra-Zeneca) and insulin pumps, away from the more traditional therapies used (classic insulin therapy, oral hypoglycaemics).

This book outlines these new technologies/treatments by collating the best journal articles published in the last year, and providing expert analysis on each one.

Advanced Technologies and Treatment for Diabetes 3E brings together and critically analyses the last year's most important articles published in the world's leading medical journals on this topic. Chapters are focused on the most current hot topic areas such as: new methods of insulin delivery; internet and IT use in treatment of diabetes; bariatric surgery & diabetes; and immunotherapy for type 1 diabetes.

Each chapter includes abstracts of the published articles, scientific conclusions made, as well as annotations and a comments and analysis section from the relevant chapter editor, each of which being a well-known expert in the field.

All researchers in the fields of diabetes, endocrinology and metabolism will find this book extremely useful, as will diabetes technology developers, and specialist endocrinologists involved with the care of diabetic patients.

Endocrine Diseases - Risk Factors, Diagnosis & Management (Hardcover): Kenneth Hines Endocrine Diseases - Risk Factors, Diagnosis & Management (Hardcover)
Kenneth Hines
R3,774 Discovery Miles 37 740 Ships in 12 - 17 working days

The human body's endocrine system includes eight major glands, which make hormones and travel through the bloodstream to tissues or organs. In this book, the authors' focus on the risk factors, genetics, diagnosis and management of gynecomastia (a benign condition characterized by enlargement of the male breast) and addresses the puzzling controversies surrounding menopausal hormone replacement therapy (HRT) and its health outcomes, which have been the subject of extensive investigation in recent years. The book concludes with a bibliography on recent titles published in the field that readers might find of interest.

Forensic Aspects of Hypoglycaemia - First Edition (Paperback): Vincent Marks Forensic Aspects of Hypoglycaemia - First Edition (Paperback)
Vincent Marks
R2,306 Discovery Miles 23 060 Ships in 12 - 17 working days

The Forensic Aspects of Hypoglycaemia succinctly covers the medicolegal considerations of hypoglycaemia in a variety of scenarios including driving fatalities, petty crime, homicide and suicide. Covering the definitions and diagnosis of hypoglycaemia to its bearing on criminal behavior, this book draws on the author's extensive experience and contains a wealth of information for physicians and lawyers, including cases from the author's past and notable cases in the public domain.

Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome (Paperback): Helmut Sies Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome (Paperback)
Helmut Sies
R1,866 Discovery Miles 18 660 Ships in 12 - 17 working days

Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central role in the progression of the syndrome. Evidence of inflammatory processes in accumulated fat appears to be an early initiator of metabolic syndrome. Likewise, the more active angiotensin system in obesity may contribute to even greater oxidative stress that serves as a key signaling event in vascular remodeling. These factors strengthen obesity's association with oxidative stress. Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome is designed to encourage the development of evidence-based nutritional and pharmacological therapies that can attenuate the impact of obesity-induced insulin resistance and ensuing metabolic syndrome. The book offers a deep understanding of the molecular mechanisms that underlie the process. Edited by leading authorities on oxidative stress, the book's chapters report on cutting-edge research that explores intracellular events mediating or preventing oxidative stress and pro-inflammatory processes in obesity and type 2 diabetes. It also brings together research on the molecular mechanisms inherent in the progression of metabolic stress, includes phenotypic perspectives, and discusses dietary factors, including the role of micronutrients. The chapter authors, each a leading expert in his or her field, discuss different components of metabolic stress and obesity and their associations with oxidative stress and inflammation. The book fills a unique role as a base of knowledge for researchers seeking to develop nutritional and or pharmacological therapies, as well as clinicians seeking a better understanding of this increasingly common dis

Medical Management of Thyroid Disease, Third Edition (Hardcover, 3rd edition): David S. Cooper, Jennifer Sipos Medical Management of Thyroid Disease, Third Edition (Hardcover, 3rd edition)
David S. Cooper, Jennifer Sipos
R5,115 Discovery Miles 51 150 Ships in 12 - 17 working days

The Third Edition of Medical Management of Thyroid Disease provides the most up-to-date practical guidance for the diagnosis and management of common and uncommon thyroid diseases. It reflects the advancement in guidelines and research for thyroid cancer, nodules and hypothyroidism; all presented in an accessible format with more illustrations and algorithms for management. The contributions of internationally renowned endocrinologists present the clinical aspects from the world's perspective. Key Features * Completely revised and updated * Reorganized with more algorithms for quick reference and enhanced usability * Edited by internationally renowned physicians in the field * Authoritative, comprehensive and yet easily digestible

Transsphenoidal Surgery - Complication Avoidance and Management Techniques (Hardcover, 1st ed. 2017): Edward R. Laws, Aaron A.... Transsphenoidal Surgery - Complication Avoidance and Management Techniques (Hardcover, 1st ed. 2017)
Edward R. Laws, Aaron A. Cohen-Gadol, Theodore H. Schwartz, Jason P Sheehan
R4,998 R4,527 Discovery Miles 45 270 Save R471 (9%) Ships in 12 - 17 working days

This work details contemporary clinical knowledge on the multidisciplinary management of pituitary and other sellar/parasellar tumors, with a focus on surgical techniques and a particular emphasis on complication avoidance and management. International experts provide guidance on natural history, radiologic and clinical aspects, surgical indications, and resection techniques.In addition, case presentations and clinical photographs help the reader reduce the risk of error and advance their own surgical skills. Readers also have access online to streaming videos of key procedures to help them provide the best possible outcomes for every patient. Transsphenoidal Surgery: Complication Avoidance and Management Techniques will be of great value to Neurosurgeons, Otolaryngologists, Endocrinologists, Radiation Oncologists, and residents and fellows in these specialties.

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach (Paperback): Anirudh Nath, Rajeeb Dey,... Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach (Paperback)
Anirudh Nath, Rajeeb Dey, Valentina E. Balas
R3,613 Discovery Miles 36 130 Ships in 12 - 17 working days

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult.

Practical Diabetes Care 4e (Paperback, 4th Edition): D Levy Practical Diabetes Care 4e (Paperback, 4th Edition)
D Levy
R1,582 Discovery Miles 15 820 Ships in 12 - 17 working days

Winner in the Internal Medicine category at the 2019 British Medical Association awards. Concise, affordable and extremely practical, Practical Diabetes Care, 4th edition offers a wholly clinical approach to diabetes and its treatment. Covering all the practical aspects of all major aspects of Type 1 and Type 2 diabetes, it also includes the very latest in clinical research and trial results. Structured in a problem-orientated way, the book focuses on the areas of maximum anxiety for health-professionals treating patients with diabetes, e.g. hyperglycaemic emergencies, and multiple complications. Easy to navigate, clear and convenient for when on the wards and in clinic, this is the perfect guide to the practical aspects of caring for patients with diabetes.

The Sweet Bloods of Eeyou Istchee - Stories of Diabetes and the James Bay Cree (Paperback): James Bay Cree Storytellers, Ruth... The Sweet Bloods of Eeyou Istchee - Stories of Diabetes and the James Bay Cree (Paperback)
James Bay Cree Storytellers, Ruth Dyckfehderau
R801 R668 Discovery Miles 6 680 Save R133 (17%) Ships in 10 - 15 working days

In this groundbreaking collection, Ruth DyckFehderau and twenty-seven storytellers offer a rich and timely accounting of contemporary life in Eeyou Istchee, the territory of the James Bay Cree of Northern Quebec. The stories are connected by diabetes, but they are not records of illness as much as they are deeply personal accounts of life in the North: the fine, swayingbalances of living both in town and on the land, of family and work and studies, of healing from relocations and residential school histories while building communities of safety and challenge and joy, of hunting and hockey, and much more.Sweet Bloods is essential reading for anyone who knows anyone with diabetes, and for anyone interested in a contemporary rendering of one of Canada's vibrant, thriving, and highly adaptive Indigenous communities.

Managing the Diabetic Foot 3e (Paperback, 3rd Edition): M. Edmonds Managing the Diabetic Foot 3e (Paperback, 3rd Edition)
M. Edmonds
R1,359 Discovery Miles 13 590 Ships in 12 - 17 working days

Foot problems in diabetic patients are some of the most challenging complications to treat, due to an often quite late presentation of symptoms from the patient. Therefore visual recognition of presenting clinical signs is absolutely key for a successful diagnosis and subsequently, the right management programme.

The 3rd edition of Managing the Diabetic Foot once again provides a practical, handy and accessible pocket guide to the clinical management of patients with severe feet problems associated with diabetes, such as ulcers, infections and necrosis. By focusing on the need for a speedy response to the clinical signs, it will enable doctors make rapid, effective management decisions in order to help prevent deterioration and avoid the need for evental foot amputation.

Each chapter focuses specifically on the different stages of foot disease and the clinical management required at that particular stage, ie, the normal foot; high-risk foot, ulcerated foot, infected foot, necrotic foot and unsalvageable foot.Full colour throughout, it will feature over 150 clinical photos, numerous hints and tips to aid rapid-reference, as well as the latest national and international guidelines on diabetic foot management.Managing the Diabetic Foot, 3E, is the ideal go-to clinical tool for all diabetes professionals, specialist diabetes nurses and podiatrists managing patients with diabetic foot problems.

Respiratory Neurobiology, Volume 188 - Physiology and Clinical Disorders, Part I (Hardcover): Robert Chen, Patrice G. Guyenet Respiratory Neurobiology, Volume 188 - Physiology and Clinical Disorders, Part I (Hardcover)
Robert Chen, Patrice G. Guyenet
R5,625 Discovery Miles 56 250 Ships in 12 - 17 working days

Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases.

Herbs for Diabetes and Neurological Disease Management - Research and Advancements (Hardcover): Vikas Kumar, Addepalli... Herbs for Diabetes and Neurological Disease Management - Research and Advancements (Hardcover)
Vikas Kumar, Addepalli Veeranjaneyulu
R3,925 Discovery Miles 39 250 Ships in 12 - 17 working days

This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies. Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique. This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.

The Pituitary (Hardcover, 4th edition): Shlomo Melmed The Pituitary (Hardcover, 4th edition)
Shlomo Melmed
R4,236 Discovery Miles 42 360 Ships in 12 - 17 working days

The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

Advances in the Assessment of Dietary Intake. (Hardcover): Dale A. Schoeller, M. Westerterp Advances in the Assessment of Dietary Intake. (Hardcover)
Dale A. Schoeller, M. Westerterp
R5,115 Discovery Miles 51 150 Ships in 12 - 17 working days

Diet is a major factor in health and disease. Controlled, long-term studies in humans are impractical, and investigators have utilized long-term epidemiological investigations to study the contributions of diet to the human condition. Such studies, while valuable, have often been limited by contradictory findings; a limitation secondary to systematic errors in traditional self-reported dietary assessment tools that limit the percentage of variances in diseases explained by diet. New approaches are available to help overcome these limitations, and Advances in the Assessment of Dietary Intake is focused on these advances in an effort to provide more accurate dietary data to understand human health. Chapters cover the benefits and limitations of traditional self-report tools; strategies for improving the validity of dietary recall and food recording methods; objective methods to assess food and nutrient intake; assessment of timing and meal patterns using glucose sensors; and physical activity patterns using validated accelerometers. Advances in the Assessment of Dietary Intake describes new avenues to investigate the role of diet in human health and serves as the most up-to-date reference and teaching tool for these methods that will improve the accuracy of dietary assessment and lay the ground work for future studies.

Thyroid Cancer - From Emergent Biotechnologies to Clinical Practice Guidelines (Paperback): Angelo Carpi, Jeffrey I. Mechanick Thyroid Cancer - From Emergent Biotechnologies to Clinical Practice Guidelines (Paperback)
Angelo Carpi, Jeffrey I. Mechanick
R1,880 R1,293 Discovery Miles 12 930 Save R587 (31%) Ships in 12 - 17 working days

The current age of clinical medicine is witnessing biotechnological innovation at an unprecedented pace. As a result, the recently popularized clinical practice guidelines (CPG), as a tool to assist clinical decision-making, have been struggling to keep up. Thyroid Cancer: From Emergent Biotechnology to Clinical Practice Guidelines rides the wave of medical innovation, analyzing current and future CPG, and providing an up-to-date and comprehensive treatise on thyroid cancer, its diagnosis, and treatment. A synthesis of ideas by prominent world experts in the field of thyroid cancer research and clinical practice, Thyroid Cancer covers: Technologically-advanced diagnostic procedures and therapeutic interventions Diagnostic techniques employed in the detection and follow-up of thyroid cancer including ultrasound, needle aspiration techniques, CT, PET, PET-CT, and MRI Basic principles of systems biology, molecular and translational medicine, CPG development, and risk stratification for thyroid cancer How CPG contain knowledge gaps and produce uncertainty Advances in the field, including new surgical techniques, molecular targeted therapies, external beam radiation therapy, and chemotherapy A comprehensive, scientific description of current and future diagnostic and therapeutic modalities for the management of thyroid cancer, this treatise is an indispensible reference for both the specialist and referring physician.

Insulin - Deficiency, Excess and Resistance in Human Disease (Paperback): Andrew J. Krentz Insulin - Deficiency, Excess and Resistance in Human Disease (Paperback)
Andrew J. Krentz
R3,044 Discovery Miles 30 440 Ships in 12 - 17 working days

Insulin: Deficiency, Excess and Resistance in Human Disease provides an overview of the role of insulin in the pathogenesis of prevalent non-communicable diseases such as obesity, type 2 diabetes, cardiovascular disease, and cancer, along with a comprehensive review of insulin replacement therapies and novel cardioprotective and insulin-sensitizing drugs. Notable advances in precision diagnosis and therapy for single gene subtypes of diabetes in recent years are also discussed. The discovery of insulin and its lifesaving introduction into clinical practice is one of the most celebrated accomplishments of medical science. However, despite decades of progress and major technical advances, the goal of providing insulin replacement therapy that truly mimics normal physiology remains elusive.

Oxford Handbook of Endocrinology & Diabetes (Paperback, 4th Revised edition): Katharine Owen, Helen Turner, John Wass Oxford Handbook of Endocrinology & Diabetes (Paperback, 4th Revised edition)
Katharine Owen, Helen Turner, John Wass
R924 R837 Discovery Miles 8 370 Save R87 (9%) Ships in 6 - 10 working days

The indispensable guide to all aspects of clinical care, the Oxford Handbook of Endocrinology and Diabetes has been fully updated for its fourth edition, providing comprehensive coverage of both disciplines in a practical and concise format. Featuring new chapters on transition in endocrinology and diabetes, practical nursing considerations, and the genetics of endocrinology, and expanded sections on inherited endocrine syndromes and MEN, it retains the clear organisation and layout for ease of reference as the previous edition over a broader range of topics. Combining authority, relevance, and reliability, this title includes new therapies and guidelines alongside 'clinical pearl' and 'tricky situation' boxes to aide readers in rare or complicated situations. This is the must-have guide for all trainees and specialist nurses in endocrinology and diabetes.

Reversing Diabetes (Paperback): Don Colbert Reversing Diabetes (Paperback)
Don Colbert
R483 R411 Discovery Miles 4 110 Save R72 (15%) Ships in 10 - 15 working days

It is possible to manage and even reverse diabetes through natural means, and in "Reversing Diabetes," Dr. Colbert shows you how. Most people view diabetes as a dead-end street. Once you receive a diabetes diagnosis, your only option is to manage the symptoms with a restricted diet, close monitoring of blood sugar, and expensive medications. Dr. Colbert shows that diabetes can be treated instead through safe, natural means, like healthy food and vitamins rather than strictly relying on prescription drugs. He shows you how to manage your weight and your glucose intake with a whole-body approach, using nutritional supplements along with dietary and lifestyle changes to lose weight, repair cell damage, improve insulin function, and reduce the side effects from prescription drugs, many of which rob nutrients from the body and cause additional symptoms.
Based on the same life-changing principles of the low-glycemic, high-fiber eating plan provided in Dr. Colbert's "New York Times "best-selling book, "Dr. Colbert's "I Can Do This" Diet," this book adapts that plan in a way that makes it ideal for diabetics who need to manage their glucose levels and their weight. "Siloam, an imprint of Charisma House Book Group, is the leader in the Christian health and fitness genre, with several best-sellers...including Don Colbert's The Bible Cure series." --"Christian Retailing" "Physician Don Colbert Preaches The Gospel Of Good Nutrition, Advising His Patients To Follow In The Footsteps Of One Of History's Better-known Role Models." --"Orlando Sentinel"

Healing the Thyroid with Ayurveda - Natural Treatments for Hashimoto's, Hypothyroidism, and Hyperthyroidism (Paperback):... Healing the Thyroid with Ayurveda - Natural Treatments for Hashimoto's, Hypothyroidism, and Hyperthyroidism (Paperback)
Marianne Teitelbaum; Foreword by Anjali Grover
R410 R374 Discovery Miles 3 740 Save R36 (9%) In Stock

A comprehensive guide to addressing the growing epidemic of thyroid disease from the perspective of the Ayurvedic tradition In this comprehensive guide for practitioners and those concerned with thyroid health, Marianne Teitelbaum, D.C., integrates the ancient medicine of Ayurveda with modern scientific findings to address the growing epidemic of thyroid disease. Revealing how the thyroid is the victim of many factors that conspire to create ill health--and how many cases of thyroid disease go undiagnosed--Teitelbaum focuses not only on treating thyroid problems and symptoms but also on diagnosing them at their earliest, most reversible stages. She outlines the basic principles of Ayurveda, including pulse diagnosis, a key tool for early detection, and explains the successful treatment protocols she has developed over more than 30 years of Ayurvedic practice. She details the underlying reasons for thyroid malfunction, such as inflammation, malnutrition, and toxins, and how the thyroid is connected with the health of the rest of body, including the liver and gall bladder. She explores the Ayurvedic treatment of thyroid-related conditions, such as Hashimoto's disease, hypothyroidism, and hyperthyroidism, offering guidance on the targeted use of herbs, specific dietary recommendations, proper detoxification, and Ayurvedic recipes. She also includes treatments and remedies for common symptoms of thyroid disease, including insomnia, depression, fatigue, and osteoporosis, as well as for luxurious hair growth and weight loss. Based on the treatment of more than 90,000 patients, this book also shares success stories of thyroid healing and the scientific studies that support the author's Ayurvedic thyroid protocols. Offering an easy-to-follow yet comprehensive guide, Teitelbaum shows that optimum thyroid health as well as overall health are within everyone's reach.

Precision Medicine in Neurodegenerative Disorders, Volume 192 - Part I (Hardcover): Alberto J. Espay Precision Medicine in Neurodegenerative Disorders, Volume 192 - Part I (Hardcover)
Alberto J. Espay
R5,606 Discovery Miles 56 060 Ships in 12 - 17 working days

Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 deals with the "Why" in the approach to slow the progression of those suffering from diseases of accelerated brain aging. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. This first Handbook of Clinical Neurology volume is intended to provide a scholarly background on the framework, basic science, and conceptual pitfalls related to disease-modifying efforts in Parkinson, Alzheimer, and other neurodegenerative disorders. Among the topics covered are the different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration.

Adrenal Disorders - 100 Cases from the Adrenal Clinic (Hardcover): William F. Young, Irina Bancos Adrenal Disorders - 100 Cases from the Adrenal Clinic (Hardcover)
William F. Young, Irina Bancos
R2,850 Discovery Miles 28 500 Ships in 12 - 17 working days

Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by ultrasound scans, biopsy images, and tables. Features 100 two-page cases covering a wide range of common and uncommon adrenal disorders. Includes case report, investigations, treatment, and outcome for each case, plus a case overview with expert advice, take-home points, and references. Organizes comprehensive content by type of disorder, including adrenal masses (benign and malignant), primary aldosteronism, ACTH-independent Cushing syndrome, ACTH-dependent Cushing syndrome, adrenal carcinoma, pheochromocytoma, adrenal and ovarian hyperandrogenism, and adrenal disorders in pregnancy. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Gigantism and Acromegaly (Paperback): Constantine A. Stratakis Gigantism and Acromegaly (Paperback)
Constantine A. Stratakis
R2,615 Discovery Miles 26 150 Ships in 12 - 17 working days

Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

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