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Books > Medicine > Clinical & internal medicine > Endocrinology

Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases (Hardcover, 1st ed. 2018): Senthilkumar Rajagopal, Murugavel... Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases (Hardcover, 1st ed. 2018)
Senthilkumar Rajagopal, Murugavel Ponnusamy
R2,873 Discovery Miles 28 730 Ships in 10 - 15 working days

This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.

Obesity, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-3 (Hardcover): Caroline M. Apovian,... Obesity, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-3 (Hardcover)
Caroline M. Apovian, Nawfal Istfan
R2,664 Discovery Miles 26 640 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Caroline M. Apovian and Nawfal Istfan, is devoted to Obesity. Articles in this comprehensive issue include: Guidelines for Obesity Management; Obesity is a Disease; Pharmacotherapy for Obesity; Bariatric Surgery Mechanisms; Diabetes Treatment in the Patient with Obesity; Adipose Tissue: Inflammation and the Endocrine Organ; Behavioral Treatment of the Patient with Obesity; The Role of Macronutrient Content in the Diet for Weight Loss and Weight Maintenance; Substrate Oxidation and Brown Adipose Tissue; Brown and Beige Adipose Tissue: Therapy for Obesity?; Ethnic Differences in Diabetes Lipids HTN and Obesity; Genetics of Bariatric Surgery Outcomes; Leptin and Hormones: Energy Homeostatis; Bariatric Surgery Clinical Outcomes; Medical Devices for Obesity; Adolescent Bariatric Surgery; Psychological Aspects of Obesity; and Nutrient Timing.

Alcohol and Hormones (Hardcover): Ronald Ross Watson Alcohol and Hormones (Hardcover)
Ronald Ross Watson
R2,603 Discovery Miles 26 030 Ships in 12 - 19 working days

In Alcohol and Hormones, leading researchers concisely review what is known about each human hormone system and how these systems are affected by alcohol use, to a lesser extent, other drugs of abuse. The contributors show clearly just how the body is regulated and how its normal functioning can be changed by alcohol.
Major topics covered range from alcohol-stress interactions and the effects of alcohol on vitamin A metabolism (fetal alcohol syndrome and neural tube development) to how alcohol blocks the release of various peptide hormones, to its effects on puberty-related events in the female. There are also articles about how alcohol affects the control of body temperature, the impact of alcohol on male sexual development during puberty, the role of TRH in alcohol use disorders, and the possibility for a neuroendocrinological component in alcoholism.
Alcohol and Hormones will be of interest to biomedical and alcohol researchers, neurobiologists, endocrinologists, pharmacologists, psychiatrists, and some clinicians interested in a deeper understanding of the effects of alcohol on the body.

Hypoglycemia - Causes and Occurrences (Hardcover): Everlon Rigobelo Hypoglycemia - Causes and Occurrences (Hardcover)
Everlon Rigobelo
R3,374 Discovery Miles 33 740 Ships in 10 - 15 working days
Type 1 Diabetes - Complications, Pathogenesis, and Alternative Treatments (Hardcover): Chih-Pin Liu Type 1 Diabetes - Complications, Pathogenesis, and Alternative Treatments (Hardcover)
Chih-Pin Liu
R3,937 Discovery Miles 39 370 Ships in 10 - 15 working days
Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-2 (Hardcover): Robert... Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-2 (Hardcover)
Robert Rapaport
R2,667 Discovery Miles 26 670 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics, edited by Dr. Robert Rapaport, is devoted to Pediatric Endocrinology. Articles in this issue include: Thyroid Cancer in Pediatrics; Gender and Sex Assignment; CAH Prenatal Diagnosis; Diabetes; Polycystic Ovarian Disease; Newborn Screening for X-linked ALD; Growth in Patients w/ Skeletal Dysplasia; Thyroid Imaging in Infants; Bariatric Surgery in Youth; Pituitary Imaging in Pediatrics; and Cardiac and Metabolic Features of GH Deficiency.

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity (Hardcover, 1st ed. 2017): Franck Mauvais-Jarvis Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity (Hardcover, 1st ed. 2017)
Franck Mauvais-Jarvis
R8,474 Discovery Miles 84 740 Ships in 10 - 15 working days

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on "Sex and gender factors affecting metabolic homeostasis, diabetes and obesity" to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

AMP-activated Protein Kinase (Hardcover, 1st ed. 2016): Mario D. Cordero, Benoit Viollet AMP-activated Protein Kinase (Hardcover, 1st ed. 2016)
Mario D. Cordero, Benoit Viollet
R6,972 Discovery Miles 69 720 Ships in 12 - 19 working days

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.

Lipidology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-1 (Hardcover): Edward A. Gill,... Lipidology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 45-1 (Hardcover)
Edward A. Gill, Christie M Ballantyne, Kathleen L Wyne
R2,664 Discovery Miles 26 640 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics examines the timely topic of Lipidology. In addition to the New Recommendations - ACC/AHA Lipid Guidelines, the issue also includes Familial Hypercholesterolemia; LDL Apheresis; Lipids in Pregnancy and Women; Diabetes and Lipidology; Diabetic Dyslipidemia; Fatty Liver Disease; Lipids and HIV Disease; Residual Risk; and Statins' effects on diabetes, cognition, and liver safety.

Encyclopedia of Endocrinology: Volume IV (Basic and Clinical Updates) (Hardcover): Joy Foster Encyclopedia of Endocrinology: Volume IV (Basic and Clinical Updates) (Hardcover)
Joy Foster
R3,495 R3,154 Discovery Miles 31 540 Save R341 (10%) Ships in 10 - 15 working days
Encyclopedia of Diabetes: Volume 05 (Managing Type 1 Diabetes) (Hardcover): Rex Slavin, Windy Wise Encyclopedia of Diabetes: Volume 05 (Managing Type 1 Diabetes) (Hardcover)
Rex Slavin, Windy Wise
R3,133 Discovery Miles 31 330 Ships in 12 - 19 working days
Clinical Rounds in Endocrinology - Volume I - Adult Endocrinology (Hardcover, 2015 ed.): Anil Bhansali, Yashpal Gogate Clinical Rounds in Endocrinology - Volume I - Adult Endocrinology (Hardcover, 2015 ed.)
Anil Bhansali, Yashpal Gogate
R4,584 Discovery Miles 45 840 Ships in 12 - 19 working days

This book covers interesting and yet often challenging cases among adult patients in a unique Question-Answer format. Simulating the bed-side case discussions during the ward rounds, one question logically leads to another question thereby generating curiosity and promoting evidence-based medicine. Taking the readers through the entire spectrum starting from etiology and pathophysiology to clinical presentation to management principles, each question addresses one key aspect of the disorder. Described in a very simple and lucid narrative, this book ensures sound conceptual understanding while covering each topic comprehensively. This volume covers important topics such as acromegaly, Cushing syndrome, osteoporosis, hypercalcemia, pheochromocytoma, hyperaldosteronism, thyroid disorders and diabetes in adult patients. These cases are not only seen by endocrinologists, but are also managed by internists, orthopedic surgeons, obstetricians and gynecologists. Less common disorders such as adrenal disorders and androgen excess have also been covered.

Encyclopedia of Endocrinology: Volume III (State-Of-The-Art Therapies) (Hardcover): Joy Foster Encyclopedia of Endocrinology: Volume III (State-Of-The-Art Therapies) (Hardcover)
Joy Foster
R2,587 R2,355 Discovery Miles 23 550 Save R232 (9%) Ships in 10 - 15 working days
Sarcoidosis, An Issue of Clinics in Chest Medicine, Volume 36-4 (Hardcover): Robert Phillip Baughman Sarcoidosis, An Issue of Clinics in Chest Medicine, Volume 36-4 (Hardcover)
Robert Phillip Baughman
R1,813 Discovery Miles 18 130 Ships in 12 - 19 working days

This issue of Clinics in Chest Medicine focuses on Sarciodosis. Drs. Baughman and Culver have put together a, expert roster of authors for articles concerning: Etiology of sarcoidosis, Immunology of sarcoidosis, Genetics of Sarcoidosis, Diagnosis of sarcoidosis, Chest imaging, Biomarkers and genetic profiles, Pulmonary Sarcoidosis, Neurosarcoidosis, Cardiac Sarcoidosis, Ocular Sarcoidosis, Quality of life assessments, and more!

Reproductive Consequences of Pediatric Disease, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-4... Reproductive Consequences of Pediatric Disease, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-4 (Hardcover)
Peter A. Lee
R1,793 Discovery Miles 17 930 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics of North America is devoted to Reproductive Endocrinology. Guest Editors Peter Lee, MD and Christopher P. Houk, MD have assembled a group of expert authors to review the following topics: Fertility Among Females and Males with Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency); Reproductive Issues for Turner Syndrome; Fertility and Reproduction Among Childhood Cancer Survivors; Fertility After Crypotochidism; Male Obesity and Fertility; Fertility Issues among Transgender Individuals; Fertility Preservation in Pediatrics; Polycystic Ovary Syndrome (PCOS); Fertility Issues for Patients With Delayed Puberty (Constitutional Delay, Functional Delay, and Hypogonadotropism); Varicocele; Testis Development and Reproduction in Klinefelters Syndrome; and Fertility Issues Among Those With Disorders of Sex Development.

Encyclopedia of Diabetes: Volume 03 (Diagnosis and Treatment) (Hardcover): Rex Slavin, Windy Wise Encyclopedia of Diabetes: Volume 03 (Diagnosis and Treatment) (Hardcover)
Rex Slavin, Windy Wise
R4,317 R3,132 Discovery Miles 31 320 Save R1,185 (27%) Ships in 12 - 19 working days
Postmenopausal Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-3 (Hardcover):... Postmenopausal Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-3 (Hardcover)
Nanette Santoro
R1,786 Discovery Miles 17 860 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics, edited by Drs. Nanette Santoro and Lubna Pal, is devoted to Postmenopausal Endocrinology. Articles in this issue include: Endocrinology of Menopause; Menopausal Symptoms; Bone Health and Osteoporosis; Surgical Menopause; Premature Menopause; Cardiovascular Changes; MHT: Current Considerations; Breast Cancer and Hormones; Other Cancers and Menopause; CAM for Menopausal Symptoms; Menopause and Sexuality; and Menopause and Metabolism.

The Effects of Family History on Patient Health Behavior - An Examination of Youths With Type 1 and Type 2 Diabetes... The Effects of Family History on Patient Health Behavior - An Examination of Youths With Type 1 and Type 2 Diabetes (Hardcover)
Rwanda Aker
R2,234 Discovery Miles 22 340 Ships in 10 - 15 working days
Pediatric Endocrinology and Diabetes, An Issue of Pediatric Clinics of North America, Volume 62-4 (Hardcover, UK ed.): Denis... Pediatric Endocrinology and Diabetes, An Issue of Pediatric Clinics of North America, Volume 62-4 (Hardcover, UK ed.)
Denis Daneman
R1,802 Discovery Miles 18 020 Ships in 12 - 19 working days

The Guest Editors have compiled a comprehensive issue that includes both disorders of endocrinology as well as diabetes. Authors have addressed the following clinical topics: disorders of menstruation, thyroid function; gender dysphoria; hypoglycemia in the nondiabetic child; preventing DKA; short- and long-term outcomes in diabetes, and whole genome sequencing in endocrinology. These topics represent the current knowedge in the field, and pediatricians will have the most updated clinical information as they evaluate and treat children with diabetes or endocrinology disorders.

Reproductive Endocrinology, An Issue of Obstetrics and Gynecology Clinics, Volume 42-1 (Hardcover, Uk Ed.): Michelle L. Matthews Reproductive Endocrinology, An Issue of Obstetrics and Gynecology Clinics, Volume 42-1 (Hardcover, Uk Ed.)
Michelle L. Matthews
R1,795 Discovery Miles 17 950 Ships in 12 - 19 working days

This issue will focus on the most common reproductive endocrine conditions encountered by healthcare providers. This series is timely and will be of interest to readers as there are many recent updates to the recommendations for appropriate evaluation and treatment of several reproductive conditions. Each chapter will address specific anatomic and hormonal conditions and will examine reproductive function from puberty to menopause. A thorough summary of abnormal uterine bleeding including recent 2012 updates for evaluation and management will be emphasized. Individual chapters on anatomic causes of bleeding, such as uterine fibroids and endometriosis, will be included with a focus on new treatment options. Polycystic ovarian syndrome (PCOS), a common hormonal cause of irregular bleeding and infertility, will also be reviewed. Recent studies provide insight into new fertility treatments for patients with PCOS including the use of aromatase inhibitors for ovulation induction. Other fertility related chapters include the evaluation of the infertile woman, ovulation induction, recurrent pregnancy loss, and age-related infertility. Finally, a transition to premature ovarian insufficiency and menopause will be provided. The Women's Health Initiative publication in 2002 reported an association between hormone replacement therapy and breast cancer. There are several updates since this controversial publication and recent literature will be summarized. Attention will focus on appropriate evaluation and management of these common reproductive endocrine topics reviewing recent recommendations on best practices for clinicians.

Diabetes and Its Complications (Hardcover): Ahmed R. G. Diabetes and Its Complications (Hardcover)
Ahmed R. G.
R3,347 Discovery Miles 33 470 Ships in 10 - 15 working days
Adrenal Cortical Neoplasia, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-2 (Hardcover): Alice... Adrenal Cortical Neoplasia, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 44-2 (Hardcover)
Alice Levine
R1,802 Discovery Miles 18 020 Ships in 12 - 19 working days

This issue of Endocrinology and Metabolism Clinics, edited by Dr. Alice Levine, is devoted to Adrenal Disease. This issue will be broken down into 3 sections: Overview of Adrenal Cortical Development, Steroidogenesis, Comparative Anatomy and Molecular Pathophysiology; Benign Adrenal Tumors; and Adrenal Cortical Carcinoma. Articles in this issue include: Adrenal Cortical Zonal Development; Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia; Animal Models of Adrenocortical Tumorigenesis; Genetics of Adrenal Cortical Tumors; Adrenal Incidentalomas; Aldosteronomas - Challenges in Diagnosis and Management; Mild Hypercortisolism Due to Adrenal Adenomas - Definitions and Therapeutic Options; Management of Adrenal Tumors in Pregnancy; Pathology of ACC; Diagnosis and Medical Management of ACC; and Surgical Management of ACC.

Management of Pancreatic Neuroendocrine Tumors (Hardcover, 2015 ed.): Joseph R. Pisegna Management of Pancreatic Neuroendocrine Tumors (Hardcover, 2015 ed.)
Joseph R. Pisegna
R4,095 R3,501 Discovery Miles 35 010 Save R594 (15%) Ships in 12 - 19 working days

This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.

Diabetes - Damages and Treatments (Hardcover): Everlon Rigobelo Diabetes - Damages and Treatments (Hardcover)
Everlon Rigobelo
R3,900 Discovery Miles 39 000 Ships in 10 - 15 working days
Encyclopedia of Endocrinology: Volume I (Advanced Topics) (Hardcover): Joy Foster Encyclopedia of Endocrinology: Volume I (Advanced Topics) (Hardcover)
Joy Foster
R2,526 Discovery Miles 25 260 Ships in 12 - 19 working days
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