Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency

Accessible information on the causes, health risks, and treatment of prediabetes

If you or someone you love has been diagnosed with prediabetes - a heightened level of glucose, and/or impaired glucose tolerance - the time to act is now. "Prediabetes For Dummies" examines the signs and symptoms of this potential precursor to diabetes and offers up-to-date information about treatment. It provides clear, practical advice on steps you can take to minimize the risk of serious health consequences.

This plain-English guide shows you how to stop prediabetes in its tracks and prevent it from progressing to diabetes. You'll learn how to recognize the symptoms of this often-undiagnosed condition, and what to do if you think you may be prediabetic. You'll also discover how simple lifestyle changes, such as changes in your diet and moderate exercise, can put the brakes on prediabetes and even reverse the condition.Offers clear explanations of prediabetes causes, health risks, and treatmentIncludes the latest advances in the use of diabetes medications to treat prediabetesProvides diet suggestions, meal plans, and exercise tipsContains helpful suggestions for friends and family members who want to support a loved one with prediabetes

While there is no cure for diabetes, it can be prevented if prediabetes is diagnosed and treated early. Packed with valuable information for patients of all ages, "Prediabetes For Dummies" is an important resource for taking control of this dangerous condition.

The sixth edition of this highly popular text retains its comprehensive coverage of endocrine basics from previous editions while featuring entirely new chapters on several topics, including the assessment of endocrine function, sexual differentiation, growth regulation, the thyroid, the adrenals, and calcium homeostasis. Chapters have been updated and reorganized to make information easily accessible in concise form, and new figures and tables have been added to enhance the presentation of complex concepts. Fundamental principles of endocrine physiology are reinforced with illustrative examples from clinical observation and the limitations of current knowledge are properly identified. The ideal resource for students entering the field, the Textbook of Endocrine Physiology aims to provide for all a solid basis in fundamentals of endocrinology and for some, inspiration for the pursuit of advanced medical or graduate studies in the field.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

Instant #1 New York Times Bestseller Dr. Izabella Wentz, the author of the phenomenal New York Times bestseller Hashimoto's Thyroiditis, returns with a long-awaited, groundbreaking prescription to reverse the symptoms of this serious autoimmune condition that is becoming one of the country's fastest growing diseases. More than thirty-five million Americans currently suffer from Hashimoto's-an autoimmune disease that affects the thyroid gland and causes the body to attack its own cells. To alleviate the symptoms of this debilitating condition-including chronic cough, acid reflux, IBS, allergies, chronic pain, hair loss, brain fog, and forgetfulness-patients are often prescribed synthetic hormones that have numerous life-altering side effects. But there is a better way. Diagnosed with Hashimoto's at twenty-seven, pharmacist Dr. Izabella Wentz knows first-hand the effects of the disease, as well as the value-and limitations-of medication. The key to improved health, she argues, involves lifestyle interventions. In Hashimoto's Protocol, she outlines a proven treatment that has helped thousands heal and many others feel better-in as fast as ninety days. Drawing on her own personal experience as well as her work consulting with thousands of patients, Hashimoto's Protocol offers a practical pathway for healing and reversing the autoimmune damage at the root of the disease. The first step is a quick-start two-week detox that includes foods to eat and inflammatory foods to avoid, advice on supplements to support the liver, and an adrenal recovery plan. Next, readers create a personalized plan with foods, supplements, and other lifestyle interventions tailored to their body's own unique Hashimoto's triggers, which they can identify using self-tests included in the book. Hashimoto's Protocol also features original recipes. Grounded in the latest science, Hashimoto's Protocol is the first book to offer a proven protocol by an acknowledged expert in the field to treat this condition and help sufferers reclaim their lives.

Lose weight while enjoying delicious meals with these 125 insulin resistant recipes and meal plans to improve your health and lower your risk for type 2 diabetes. Many people struggle with their weight, trying every new diet and health trend but still are unable to keep the weight off or lose unwanted belly fat. The problem may not be lack of willpower, but insulin resistance. When insulin can't do its job of removing sugar from the blood, that sugar is turned to fat, causing weight gain and increasing the risk of type 2 diabetes. But this damage can be reversed simply by changing your diet and activity level. In The Everything Guide to the Insulin Resistance Diet, you will learn how to choose healthy foods like fruits, vegetables, whole grains, fish, and lean poultry, while limiting the amount of unhealthy fat, sugar, meats, and processed starches. Now you can make the lifestyle changes you need to lose weight and improve your health with this valuable resource that includes 125 recipes and a 10-week plan for healthy eating and increased activity. With this guidebook you can have the body-and health-of your dreams, all while eating the delicious food you love!

Wide variety of pesticides and other synthetic chemicals may disrupt the normal function of the endocrine system, cause alteration and also attack the immune system of humans and wildlife at very low concentration levels. Chapter One of this book provides an overview of analytical methods, including sample preparation steps, chromatographic separation and detection of endocrine disrupting pesticides in a variety of food, environmental and biological matrices. Chapter Two studies endocrine disrupting compound (EDC) exposure from recycled wastewater compared to other water related risks in developed and developing nations. Chapter Three summarizes the role of EDCs on pregnancy and birth outcomes, included but not limited to fertility problems, premature birth, low birth weight, and miscarriage along with in-vitro, animal, and epidemiological studies. In the last chapter, the worst EDCs will be revealed and their related potential hazardous health risks to humans are discussed. Furthermore, suggestions to help the reader avoid such toxic chemicals are presented.

The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient's quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.

This comprehensive book on Endocrine Surgery covers disorders of thyroid, parathyroid, adrenal glands along with neuroendocrine tumors of pancreas and gastrointestinal tract. It is a comprehensive, up-to-date treatise covering embryology, anatomy, etiology, clinical manifestations, diagnoses, and treatment modalities of surgical endocrine diseases. The authors explore the pertinent surgical endocrinology topics with a South Asian perspective. Color illustrations, flowcharts and tables make the topics lucid for professionals. This book provides the essential information surgeons require for evaluation and management of patients, both with straight forward, and complex endocrine problems. Key Features Focusses on concise yet comprehensive, up-to-date coverage of surgical endocrine diseases Discusses Robot Assisted Endocrine Surgery and explores its impact on healthcare finances Highlights the difference between practices used in western and resource limited countries by incorporating a South Asian perspective for region specific diseases.

The human body's endocrine system includes eight major glands, which make hormones and travel through the bloodstream to tissues or organs. In this book, the authors' focus on the risk factors, genetics, diagnosis and management of gynecomastia (a benign condition characterized by enlargement of the male breast) and addresses the puzzling controversies surrounding menopausal hormone replacement therapy (HRT) and its health outcomes, which have been the subject of extensive investigation in recent years. The book concludes with a bibliography on recent titles published in the field that readers might find of interest.

The Forensic Aspects of Hypoglycaemia succinctly covers the medicolegal considerations of hypoglycaemia in a variety of scenarios including driving fatalities, petty crime, homicide and suicide. Covering the definitions and diagnosis of hypoglycaemia to its bearing on criminal behavior, this book draws on the author's extensive experience and contains a wealth of information for physicians and lawyers, including cases from the author's past and notable cases in the public domain.

Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central role in the progression of the syndrome. Evidence of inflammatory processes in accumulated fat appears to be an early initiator of metabolic syndrome. Likewise, the more active angiotensin system in obesity may contribute to even greater oxidative stress that serves as a key signaling event in vascular remodeling. These factors strengthen obesity's association with oxidative stress. Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome is designed to encourage the development of evidence-based nutritional and pharmacological therapies that can attenuate the impact of obesity-induced insulin resistance and ensuing metabolic syndrome. The book offers a deep understanding of the molecular mechanisms that underlie the process. Edited by leading authorities on oxidative stress, the book's chapters report on cutting-edge research that explores intracellular events mediating or preventing oxidative stress and pro-inflammatory processes in obesity and type 2 diabetes. It also brings together research on the molecular mechanisms inherent in the progression of metabolic stress, includes phenotypic perspectives, and discusses dietary factors, including the role of micronutrients. The chapter authors, each a leading expert in his or her field, discuss different components of metabolic stress and obesity and their associations with oxidative stress and inflammation. The book fills a unique role as a base of knowledge for researchers seeking to develop nutritional and or pharmacological therapies, as well as clinicians seeking a better understanding of this increasingly common dis

The Third Edition of Medical Management of Thyroid Disease provides the most up-to-date practical guidance for the diagnosis and management of common and uncommon thyroid diseases. It reflects the advancement in guidelines and research for thyroid cancer, nodules and hypothyroidism; all presented in an accessible format with more illustrations and algorithms for management. The contributions of internationally renowned endocrinologists present the clinical aspects from the world's perspective. Key Features * Completely revised and updated * Reorganized with more algorithms for quick reference and enhanced usability * Edited by internationally renowned physicians in the field * Authoritative, comprehensive and yet easily digestible

The traditional agents for controlling the levels of glucose in the blood remain important therapies but they have their downside from the point of view of tolerability and side effects. Moreover, they appear not to be able to counter the natural history deterioration of the disease in terms of the onset of diabetic-related complications.

Recent years have seen an influx of new treatment therapies and technologies aimed at achieving better glycaemic control for diabetic patients such as liraglutide (Novo Nordisk) and saxagliptin (BMS/Astra-Zeneca) and insulin pumps, away from the more traditional therapies used (classic insulin therapy, oral hypoglycaemics).

This book outlines these new technologies/treatments by collating the best journal articles published in the last year, and providing expert analysis on each one.

Advanced Technologies and Treatment for Diabetes 3E brings together and critically analyses the last year's most important articles published in the world's leading medical journals on this topic. Chapters are focused on the most current hot topic areas such as: new methods of insulin delivery; internet and IT use in treatment of diabetes; bariatric surgery & diabetes; and immunotherapy for type 1 diabetes.

Each chapter includes abstracts of the published articles, scientific conclusions made, as well as annotations and a comments and analysis section from the relevant chapter editor, each of which being a well-known expert in the field.

All researchers in the fields of diabetes, endocrinology and metabolism will find this book extremely useful, as will diabetes technology developers, and specialist endocrinologists involved with the care of diabetic patients.

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult.

The market-leading text, An Introduction to Behavioral Endocrinology, Sixth Edition provides an updated, integrated presentation of the study of hormone-behavior-brain interactions. Maintaining a comparative approach, the text explores the endocrine mechanisms that have evolved in both human and nonhuman animals to solve common problems in survival and reproduction. The text describes interactions among hormones, brain, and behavior from a historical perspective, emphasizing connections among key theories and tracing the emergence of important hypotheses. The book is organized around the conceptual theme that hormones affect behavior by influencing one or more of three "components" of behaving animals-input mechanisms (such as sensory or perceptual processes), the central processing mechanisms of the nervous system (either directly, or by affecting its development or structure), and output mechanisms (such as effectors or peripheral structures). Despite increased coverage of molecular and cellular approaches, the book strives for accessibility for non-biological science students. An Introduction to Behavioral Endocrinology, Sixth Edition, is appropriate for upper-level undergraduate and graduate courses in psychology, biology, anthropology, or zoology. It contains several important pedagogical features: *Learning objectives are set out at the beginning of each chapter and now include 3 multiple choice questions per objective in the enhanced ebook. *Learning Activity in each chapter (new to this edition) *Key terms are defined in the margins throughout the text. *The text is richly illustrated with color photographs and drawings. *Chapter-end summaries restate important points. *Discussion questions and suggested further readings are also included in each chapter. *The text contains nearly 2,400 references to the literature in behavioral endocrinology. RESOURCES For Students As with previous editions, the book is accompanied by animations, video, web links, sound files, a complete glossary, and graphics-accessible via Oxford Learning Link-to aid in understanding the material in the text. This edition will also include an enhanced ebook. For Instructors -The Instructor's Resource Library includes electronic versions of all the textbook's figures and tables. All images are provided as both high- and low-resolution JPEGs, formatted and optimized for excellent legibility when projected. All figures and tables are also provided in ready-to-use PowerPoint presentations. -The Test Bank includes multiple-choice, short-answer, and essay questions for each chapter of the textbook. Prepared by the author, these questions are a helpful resource that can greatly speed the process of preparing exams and quizzes for the course.

In this groundbreaking collection, Ruth DyckFehderau and twenty-seven storytellers offer a rich and timely accounting of contemporary life in Eeyou Istchee, the territory of the James Bay Cree of Northern Quebec. The stories are connected by diabetes, but they are not records of illness as much as they are deeply personal accounts of life in the North: the fine, swayingbalances of living both in town and on the land, of family and work and studies, of healing from relocations and residential school histories while building communities of safety and challenge and joy, of hunting and hockey, and much more.Sweet Bloods is essential reading for anyone who knows anyone with diabetes, and for anyone interested in a contemporary rendering of one of Canada's vibrant, thriving, and highly adaptive Indigenous communities.

This unique handbook provides pediatric and adult endocrinologists and multidisciplinary clinical care providers a guide to transition from pediatric to adult care and an understanding of developmental and psychosocial issues of young adulthood and how they relate to healthcare and disease self-management. The handbook is divided into two parts. Part one describes transition interventions and novel strategies that can be integrated into routine care and gives practical considerations for transition processes from both the pediatric and adult perspectives, with applications across multiple endocrine conditions. Part two focuses on transition issues specific to common endocrine conditions - type 1 and type 2 diabetes, Turner syndrome, congenital adrenal hyperplasia, endocrine sequelae of childhood cancer, and transgender care - with condition-specific developmental and psychosocial issues, treatment and screening recommendations, healthcare process considerations, transition care guidelines, and key resources for more information. By highlighting medical, psychosocial, and healthcare delivery concerns relevant to transition to adult care, this book provides a practical, patient-centered overview of the essential information to supporting optimal adult care transition across a number of endocrine conditions. Timely and practical, Transitioning from Pediatric to Adult Care in Endocrinology: A Clinical Handbook is an excellent resource for pediatric and adult endocrinologists, behavioral healthcare providers, allied health professionals, primary care providers, and all clinical staff working with young people with endocrine conditions as they transition from children to adults.

Foot problems in diabetic patients are some of the most challenging complications to treat, due to an often quite late presentation of symptoms from the patient. Therefore visual recognition of presenting clinical signs is absolutely key for a successful diagnosis and subsequently, the right management programme.

The 3rd edition of Managing the Diabetic Foot once again provides a practical, handy and accessible pocket guide to the clinical management of patients with severe feet problems associated with diabetes, such as ulcers, infections and necrosis. By focusing on the need for a speedy response to the clinical signs, it will enable doctors make rapid, effective management decisions in order to help prevent deterioration and avoid the need for evental foot amputation.

Each chapter focuses specifically on the different stages of foot disease and the clinical management required at that particular stage, ie, the normal foot; high-risk foot, ulcerated foot, infected foot, necrotic foot and unsalvageable foot.Full colour throughout, it will feature over 150 clinical photos, numerous hints and tips to aid rapid-reference, as well as the latest national and international guidelines on diabetic foot management.Managing the Diabetic Foot, 3E, is the ideal go-to clinical tool for all diabetes professionals, specialist diabetes nurses and podiatrists managing patients with diabetic foot problems.

Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases.

A compelling defense of hormone replacement therapy, exposing the faulty science behind its fall from prominence and empowering women to make informed decisions about their health. For years, hormone replacement therapy (HRT) was hailed as a miracle. Study after study showed that HRT, if initiated at the onset of menopause, could ease symptoms ranging from hot flashes to memory loss; reduce the risk of heart disease, Alzheimer's, osteoporosis, and some cancers; and even extend a woman's overall life expectancy. But when a large study by the Women's Health Initiative announced results showing an uptick in breast cancer among women taking HRT, the winds shifted abruptly, and HRT, officially deemed a carcinogen, was abandoned. Now, sixteen years after HRT was left for dead, Dr. Bluming, a medical oncologist, and Dr. Tavris, a social psychologist, track its strange history and present a compelling case for its resurrection. They investigate what led the public -- and much of the medical establishment -- to accept the Women's Health Initiative's often exaggerated claims, while also providing a fuller picture of the science that supports HRT. A sobering and revelatory read, Estrogen Matters sets the record straight on this beneficial treatment and provides an empowering path to wellness for women everywhere.

This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies. Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique. This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.

The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

Winner in the Internal Medicine category at the 2019 British Medical Association awards. Concise, affordable and extremely practical, Practical Diabetes Care, 4th edition offers a wholly clinical approach to diabetes and its treatment. Covering all the practical aspects of all major aspects of Type 1 and Type 2 diabetes, it also includes the very latest in clinical research and trial results. Structured in a problem-orientated way, the book focuses on the areas of maximum anxiety for health-professionals treating patients with diabetes, e.g. hyperglycaemic emergencies, and multiple complications. Easy to navigate, clear and convenient for when on the wards and in clinic, this is the perfect guide to the practical aspects of caring for patients with diabetes.

Diet is a major factor in health and disease. Controlled, long-term studies in humans are impractical, and investigators have utilized long-term epidemiological investigations to study the contributions of diet to the human condition. Such studies, while valuable, have often been limited by contradictory findings; a limitation secondary to systematic errors in traditional self-reported dietary assessment tools that limit the percentage of variances in diseases explained by diet. New approaches are available to help overcome these limitations, and Advances in the Assessment of Dietary Intake is focused on these advances in an effort to provide more accurate dietary data to understand human health. Chapters cover the benefits and limitations of traditional self-report tools; strategies for improving the validity of dietary recall and food recording methods; objective methods to assess food and nutrient intake; assessment of timing and meal patterns using glucose sensors; and physical activity patterns using validated accelerometers. Advances in the Assessment of Dietary Intake describes new avenues to investigate the role of diet in human health and serves as the most up-to-date reference and teaching tool for these methods that will improve the accuracy of dietary assessment and lay the ground work for future studies.