Of the 758 species of hard ticks (family Ixodidae) currently known to science, 137 (18%) are found in the Neotropical Zoogeographic Region, an area that extends from the eastern and western flanks of the Mexican Plateau southward to southern Argentina and Chile and that also includes the Greater and Lesser Antilles and the Galapagos Islands. This vast and biotically rich region has long attracted natural scientists, with the result that the literature on Neotropical ticks, which are second only to mosquitoes as vectors of human disease and are of paramount veterinary importance, is enormous, diffuse, and often inaccessible to non-specialists. In this book, three leading authorities on the Ixodidae have combined their talents to produce a summary of essential information for every Neotropical tick species. Under each species name, readers will find an account of the original taxonomic description and subsequent redescriptions, followed by an overview of its geographic distribution and host relationships, including a discussion of human parasitism. Additional sections provide detailed analyses of tick distribution by country and zoogeographic subregion (the Caribbean, southern Mexico and Central America, South America, and the Galapagos Islands), together with a review of the phenomenon of invasive tick species and examination of the many valid and invalid names that have appeared in the Neotropical tick literature. The text concludes with an unprecedented tabulation of all known hosts of Neotropical Ixodidae, including the tick life history stages collected from each host. This book is an invaluable reference for biologists and biomedical personnel seeking to familiarize themselves with the Neotropical tick fauna.

The last four decades of human history have seen the emergence of an unprecedented number of 'new' infectious diseases: the familiar roll call includes AIDS, Ebola, H5N1 influenza, hantavirus, hepatitis E, Lassa fever, legionnaires' and Lyme diseases, Marburg fever, Rift Valley fever, SARS, and West Nile. The outbreaks range in scale from global pandemics that have brought death and misery to millions, through to self-limiting outbreaks of mainly local impact. Some outbreaks have erupted explosively but have already faded away; some grumble along or continue to devastate as now persistent features in the medical lexicon; in others, a huge potential threat hangs uncertainly and worryingly in the air. Some outbreaks are merely local, others are worldwide.
This book looks at the epidemiological and geographical conditions which underpin disease emergence. What are the processes which lead to emergence? Why now in human history? Where do such diseases emerge and how do they spread or fail to spread around the globe? What is the armoury of surveillance and control measures that may curb the impact of such diseases? But, uniquely, it sets these questions on the modern period of disease emergence in an historical context. First, it uses the historical record to set recent events against a much broader temporal canvas, finding emergence to be a constant theme in disease history rather than one confined to recent decades. It concludes that it is the quantitative pace of emergence, rather than its intrinsic nature, that separates the present period from earlier centuries. Second, it looks at the spatial and ecological setting of emergence, using hundreds of specially-drawn maps to chart the source areas of new diseases and the pathways of their spread. The book is divided into three main sections: Part 1 looks at early disease emergence, Part 2 at the processes of disease emergence, and Part 3 at the future for emergent diseases.

This book offers a radically different perspective on the topic of health inequity. Carey, Tai, and Griffiths use Perceptual Control Theory (PCT) to deconstruct current approaches to understanding, investigating, and addressing problems of health inequity. In the book, the authors propose that health inequity is not a problem per se. Disrupted control, they argue, is the problem that needs to be addressed. From this perspective, research, policy, and health practices directed at addressing health inequity in isolation will offer only partial solutions to the problems created by disrupted control. Addressing problems of disrupted control directly, however, has the potential to entirely resolve issues that are created by health inequity. The authors have extensive clinical and research experience in a wide range of contexts, including: cross-cultural settings; rural, remote, and underserved communities; community mental health settings; prisons; schools; and psychiatric wards. Drawing on these diverse experiences, the authors describe how adopting a Perceptual Control Theory perspective might offer promising new directions for researchers and practitioners who have an interest in addressing issues of inequity and social justice. With a Foreword written by Professor Neil Gilbert this book will provide fresh insights for academics, practitioners, and policymakers in the fields of public health, psychology, social policy, and healthcare.

Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what's new in the field and how it can benefit your patients. Features a wealth of information on epidemiology and research methods related to heart failure. Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. Consolidates today's available information and guidance in this timely area into one convenient resource.

This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

The ageing of our population is a key societal issue across the globe. Although people are living longer, they need to be living longer in good health to continue to enjoy quality of life and independence and to prevent rises in health and social care costs. This timely and ground-breaking volume will provide an up-to-date overview of the factors that promote physical activity in later life. Despite advances in the fields of gerontology and geriatrics, sports and exercise science, sociology, health psychology, and public health, knowledge is largely contained within disciplines as reflected in the current provision of academic texts on this subject. To truly address the present and substantial societal challenges of population ageing, a multidisciplinary and collaborative approach is required. This handbook will inform researchers, students, and practitioners on the current evidence base for what physical activities need to be promoted among older people and how they can be implemented to maximise engagement. This handbook will be an invaluable resource for researchers, practitioners, policy makers, and students across the social sciences.

This book is specifically designed to serve the community of postgraduates and researchers in the fields of epidemiology, health GIS, medical geography, and health management. It starts with the basic concepts and role of remote sensing, GIS in Kala-azar diseases. The book gives an exhaustive coverage of Satellite data, GPS, GIS, spatial and attribute data modeling, and geospatial analysis of Kala-azar diseases. It also presents the modern trends of remote sensing and GIS in health risk assessment with an illustrated discussion on its numerous applications.

This introductory book enables researchers and students of all backgrounds to compute interrater agreements for nominal data. It presents an overview of available indices, requirements, and steps to be taken in a research project with regard to reliability, preceded by agreement. The book explains the importance of computing the interrater agreement and how to calculate the corresponding indices. Furthermore, it discusses current views on chance expected agreement and problems related to different research situations, so as to help the reader consider what must be taken into account in order to achieve a proper use of the indices. The book offers a practical guide for researchers, Ph.D. and master students, including those without any previous training in statistics (such as in sociology, psychology or medicine), as well as policymakers who have to make decisions based on research outcomes in which these types of indices are used.

Encephalitis lethargica ('sleeping sickness') was a mysterious disorder that swept the world in the decade following the First World War, before disappearing without its cause having been identified. Around 85% of its victims, predominantly children, adolescents and younger adults, survived the acute disorder, but most developed severe neurological syndromes, particularly severe post-encephalitic parkinsonism and other severe motor abnormalities, that incapacitated them for the remainder of their lives. Despite its brief history, encephalitis lethargica played a major role in a variety medical discussions between the two World Wars, as this epitome of neuropsychiatric disease - attacking both motor and mental functions - appeared just as the separation of neurology and psychiatry had reached a critical point. Encephalitis lethargica sufferers presented an unprecedented combination of neurologic and psychiatric symptoms - including previously puzzling phenomena primarily associated with schizophrenia and hysteria, as well as behavioral changes and attention deficit disorders in children - that not only underscored the unity of mind and movement in the CNS, but also illuminated the critical role played by subcortical structures in consciousness and other higher mental functions that had formerly been associated with the soul and more recently presumed to be localized to the human cerebral cortex. Encephalitis lethargica exerted a greater influence on clinical and theoretic neuroscientific thought between the two World Wars than any other single disorder and had an enduring impact upon neurology and psychiatry. This book will be of interest to an educated audience active or interested in clinical (neurology, psychiatry, psychology) or laboratory neuroscience, particularly those interested in neuropsychiatry, as well as to those interested in the history of the biomedical sciences.

This book examines statistical methods and models used in the fields of global health and epidemiology. It includes methods such as innovative probability sampling, data harmonization and encryption, and advanced descriptive, analytical and monitory methods. Program codes using R are included as well as real data examples. Contemporary global health and epidemiology involves a myriad of medical and health challenges, including inequality of treatment, the HIV/AIDS epidemic and its subsequent control, the flu, cancer, tobacco control, drug use, and environmental pollution. In addition to its vast scales and telescopic perspective; addressing global health concerns often involves examining resource-limited populations with large geographic, socioeconomic diversities. Therefore, advancing global health requires new epidemiological design, new data, and new methods for sampling, data processing, and statistical analysis. This book provides global health researchers with methods that will enable access to and utilization of existing data. Featuring contributions from both epidemiological and biostatistical scholars, this book is a practical resource for researchers, practitioners, and students in solving global health problems in research, education, training, and consultation.

This book includes research articles and expository papers on the applications of artificial intelligence and big data analytics to battle the pandemic. In the context of COVID-19, this book focuses on how big data analytic and artificial intelligence help fight COVID-19. The book is divided into four parts. The first part discusses the forecasting and visualization of the COVID-19 data. The second part describes applications of artificial intelligence in the COVID-19 diagnosis of chest X-Ray imaging. The third part discusses the insights of artificial intelligence to stop spread of COVID-19, while the last part presents deep learning and big data analytics which help fight the COVID-19.

Global Health Informatics: How Information Technology Can Change Our Lives in a Globalized World discusses the critical role of information and communication technologies in health practice, health systems management and research in increasingly interconnected societies. In a global interconnected world the old standalone institutional information systems have proved to be inadequate for patient-centered care provided by multiple providers, for the early detection and response to emerging and re-emerging diseases, and to guide population-oriented public health interventions. The book reviews pertinent aspects and successful current experiences related to standards for health information systems; digital systems as a support for decision making, diagnosis and therapy; professional and client education and training; health systems operation; and intergovernmental collaboration.

This book is the first one in which basic demographic models are rigorously formulated by using modern age-structured population dynamics, extended to study real-world population problems. Age structure is a crucial factor in understanding population phenomena, and the essential ideas in demography and epidemiology cannot be understood without mathematical formulation; therefore, this book gives readers a robust mathematical introduction to human population studies. In the first part of the volume, classical demographic models such as the stable population model and its linear extensions, density-dependent nonlinear models, and pair-formation models are formulated by the McKendrick partial differential equation and are analyzed from a dynamical system point of view. In the second part, mathematical models for infectious diseases spreading at the population level are examined by using nonlinear differential equations and a renewal equation. Since an epidemic can be seen as a nonlinear renewal process of an infected population, this book will provide a natural unification point of view for demography and epidemiology. The well-known epidemic threshold principle is formulated by the basic reproduction number, which is also a most important key index in demography. The author develops a universal theory of the basic reproduction number in heterogeneous environments. By introducing the host age structure, epidemic models are developed into more realistic demographic formulations, which are essentially needed to attack urgent epidemiological control problems in the real world.

In the tradition of its predecessor, the main purpose of this volume is the dissemination of statistical methodologies in the area of biological and medical sciences. The chapters are written by specialists with considerable experience in the application of statistical techniques for investigating biological issues. The volume is divided into four parts and the chapters illustrate some recent work on many issues. Most of the papers discuss the statistical principles in conjunction with specific applications. As a result biological as well as statistical readers will benefit from this exposition, and obtain the current state of knowledge in these areas. Many authors emphasize the open problems that might lead to further work on these subjects.

Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.

This volume gathers together selected, peer-reviewed papers presented at the BIOMAT 2020 International Symposium, which was virtually held on November 1-6, 2020, with an organization staff based in Rio de Janeiro, Brazil. Topics covered in this volume include infection modeling, with an emphasis on different aspects of the COVID-19 and novel Coronavirus spread; a description of the effectiveness of quarantine measures via dynamic analysis of SLIR model; hemodynamic simulations in time-dependent domains; an optimal control model for the Ebola disease; and the co-existence of chaos and control in the context of biological models. Texts in agroforestry, economic development, and wastewater treatment processes complete this volume. Held every year since 2001, the BIOMAT International Symposium gathers together, in a single conference, researchers from Mathematics, Physics, Biology, and affine fields to promote the interdisciplinary exchange of results, ideas and techniques, promoting truly international cooperation for problem discussion. The 20th edition of the BIOMAT International Symposium has received contributions by authors from 18 countries: Algeria, Brazil, Cameroon, Canada, Chile, China (Hong Kong), Colombia, Germany, Hungary, India, Italy, Morocco, Nigeria, Russia, Senegal, South Africa, USA, and Uzbekistan. Previous BIOMAT volumes with selected works from 2017, 2018, and 2019 were also published by Springer.

Disease is everywhere. Everyone experiences disease, everyone knows somebody who is, or has been diseased, and disease-related stories hit the headlines on a regular basis. Many important issues in the philosophy of disease, however, have received remarkably little attention from philosophical thinkers. This book examines a number of important debates in the philosophy of medicine, including 'what is disease?', and the roles and viability of concepts of causation, in clinical medicine and epidemiology. Where much of the existing literature targets conceptual analyses of health and disease, this book provides the reader with an insight into these debates, and develops plausible alternative accounts. The author explores a range of related subjects, discussing a host of interesting philosophical questions within clinical medicine, pathology and epidemiology. In the second part of the book, the author examines the concepts of causation employed by clinicians and pathologists, how one should classify diseases, and whether the epidemiologist's models for inferring the causes of disease are all they're cracked up to be.

One of the first books on Covid-19 from an expert in emerging infectious disease.

The Coronavirus pandemic has devastated lives and livelihoods around the world - and continues to do so. These personal tragedies will, and must, be told and heard. There is, however, also a truthful and objective scientific narrative to be written about how the virus played out and how the world set about dealing with it. Spike is that story - from the inside. Its author, Jeremy Farrar, is one of the UK's leading scientists and a ? member of the SAGE emergency committee.

As head of the Wellcome Trust, and an expert in emerging infectious diseases, Jeremy Farrar was one of the first people in the world to hear about a mysterious new respiratory disease in China - and to learn that it could readily spread between people. Farrar describes how it feels as one of the key scientists at the sharp end of a fast-moving situation, when complex decisions must be made quickly amid great uncertainty. His book casts light on the UK government's claims to be 'following the science' in its response to the virus, and is informed not just by Farrar's views but by interviews with other top scientists and political figures.

Farrar, who has spent his career on the frontlines of epidemics including Nipah virus in Malaysia, bird flu in Vietnam and Ebola in West Africa, also reflects on the wider issues of Covid-19: the breath-taking scientific advances in creating tests, treatments and vaccines; the challenge to world leaders to respond for the global good and the need to address inequalities that hold back success against the virus. All these shape how the world ultimately fares not just against Covid-19, but against all the major health challenges we face globally.

The 2014-2015 Ebola outbreak in West Africa shocked the world with its devastation and its rapid migration to multiple continents. As the systems meant to respond to this sort of epidemic failed, the disease exposed not just weaknesses in international infectious disease surveillance and management, but the failures of governments, humanitarian organizations, and international institutions to handle the legal, ethical, and economic questions that arose with an event of this scale. Global Management of Infectious Disease After Ebola unites the insights of Ebola's first responders with those the world's foremost experts in law, economics, vaccine development, and global migration to identify missed opportunities from the Ebola crisis - and to apply these lessons to emerging infectious disease threats. Framed with critical discussions of both the global health financing infrastructures that precipitated the response and the ethical and human rights dilemmas that resulted from it, this volume is much more than postmortem to an outbreak: it is a vital, sometimes damning examination of where we've been and where we're going in the face of emerging infectious diseases.

This authoritative handbook reviews the most widely-used methods for studying the use and abuse of alcohol and illegal drugs. Its thorough coverage spans the range of quantitative, qualitative, and mixed-method approaches to documenting and measuring the complex psychological, behavioral, and physical experience of substance misuse and dependence, to ensure valid, useful results. Experts discuss special issues and considerations for conducting ethical research with specialized populations, including youth, inmates, and the LGBT community. Throughout these chapters, contributors demonstrate the multidisciplinary nature of substance abuse research, with emphasis on professional ethics and the critical role of research in developing best practices and effective policy for prevention and treatment. Among the topics covered: * Transdisciplinary research perspective: a theoretical framework for substance abuse research * Longitudinal methods in substance use research * Considerations in blending qualitative and quantitative components in substance abuse research * The use of biological measures in social research on drug misuse * Using surveys to study substance use behavior * Applications of GIS to inform substance abuse research and interventions * Evaluating substance use prevention and treatment programs Research Methods in the Study of Substance Abuse is an essential resource for health services and public health professionals, policymakers, and researchers working and training in the field of addiction. It encourages the rigor and understanding necessary to address widespread social and public health concerns.

For readers of Mary Roach and Jared Diamond, an innovative look at the histories of different epidemics and what it meant for society, alongside what lessons different diseases have to teach us as society battles the novel coronavirus. Throughout history, there have been numerous epidemics that have threatened mankind with destruction. Diseases have the ability to highlight our shared concerns across the ages, affecting every social divide from national boundaries, economic categories, racial divisions, and beyond. Whether looking at smallpox, HIV, Ebola, or COVID-19 outbreaks, we see the same conversations arising as society struggles with the all-encompassing question: What do we do now? In "poignant yet relevant detail" (Niki Kapsambelis, author of The Inheritance), Quarantine Life from Cholera to COVID-19 demonstrates that these conversations have always involved the same questions of individual liberties versus the common good, debates about rushing new and untested treatments, considerations of whether quarantines are effective to begin with, what to do about healthy carriers, and how to keep trade circulating when society shuts down. This vibrant social and medical history tracks different diseases and outlines their trajectory, what they meant for society, and societal questions each disease brought up, along with practical takeaways we can apply to current and future pandemics--so we can all be better prepared for whatever life throws our way.