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Selenium - Its Molecular Biology and Role in Human Health (Hardcover, 4th ed. 2016)
Loot Price: R6,343
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Selenium - Its Molecular Biology and Role in Human Health (Hardcover, 4th ed. 2016)
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In the current edition, Selenium: Its Molecular Biology and Role in
Human Health expands extensively on the previous editions providing
readers with the most significant advances in the rapidly
developing selenium field. Evidence from epidemiology and
veterinary science supports the essential role of selenium in
(human) health, but its split personality in both preventing and
supporting cancer and also in promoting insulin resistance has
become more clearly defined. The pivotal role of glutathione
peroxidase 4 in a new process of programmed cell death,
ferroptosis, brings new impetus to the field. Recently defined
mutations in selenoprotein and biosynthesis factor genes have been
identified in patients, and the resulting disorders further
emphasize the significance of selenoproteins in human health. The
mechanism of selenoprotein biosynthesis, the functions of
selenoproteins, and the roles of dietary selenium have been further
elucidated, and new regulatory mechanisms involving selenoproteins
discovered. The book, therefore, covers the breadth of current
selenium research. With up-to-date chapters written by leaders in
their fields, it serves as an invaluable resource for novices as
well as specialists.
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