Targeted Drug Delivery Novel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugs Targeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug carriers and devices, helping readers to stay up to date on the latest developments in the field. The following key topics are addressed: Antibody conjugates, prodrugs, and suicide gene therapeutics Protac technology for selectively degrading target proteins Delivery of nucleic acid drugs Novel drug carriers, such as liposomes, vesicles, and nanoparticles Unmet medical needs for which there is a large market potential, such as viral infections and cancer For chemists, pharmacologists, and professionals in the wider pharmaceutical industry, Targeted Drug Delivery is a comprehensive guide on how to solve the greatest challenge in treating many diseases: delivering a pharmaceutically active substance to the target tissue in the body.

This fascinating book will be of as much interest to engineers as to art historians, examining as it does the evolution of machine design methodology from the Renaissance to the Age of Machines in the 19th century. It provides detailed analysis, comparing design concepts of engineers of the 15th century Renaissance and the 19th century age of machines from a workshop tradition to the rational scientific discipline used today.

Metal Nano 3D Superlattices Unique view on producing metal nano 3D superlattices by differing their morphologies, crystalline structures, chemical, and physical properties After presenting an overview on the various factors involved in producing metal 3D superlattices called supracrystals by differing their morphologies, crystalline structures, chemical, physical, and intrinsic properties, Metal Nano 3D Superlattices: Synthesis, Properties, and Applications reveals the existence of new materials with unexpected properties. Readers will gain insight into the various approaches on the production and on the specific properties of nanocrystals self-assembled in 3D superlattices also called colloidal crystals, supra or super crystals. These properties open up new avenues of research and potentially aiding in major progress. Overall, the work reviews the progress of and gives perspective on assembled nanocrystals, with a concentrated focus on self-assemblies of metal nanocrystals. Sample topics covered by the highly qualified and internationally awarded author include: Syntheses of nanocrystals with low size distribution. The wide variety of self-assembled nanocrystals in 3D superlattices strongly depends on an impressive number of parameters. The intrinsic chemical and physical properties of 3D superlattices of nanocrystals opens the way to the discovery of unexpected properties. This concerns growth processes, coherent breathing of in 3D superlattices, electron transport through thick assemblies, etc. A strong analogy between atomic crystals and 3D superlattices of nanocrystals emerge: incompressible nanocrystals and coating agents act as mechanical springs holding together the nanocrystals and replace respectively, in atomic crystals, atoms and atomic bonds. The intrinsic chemical and physical properties of nanocrystals and their assemblies depend on their crystalline structures called nanocrystallinity. Collective properties due to dipolar interactions between nanocrystals are pointed out. Water soluble suprastructures act as efficient universal nanoheaters. In addition, reconstruction near the cytoplasmic membrane in tumor cells of nanocrystal self-assemblies takes place opening various biomedical applications. The physical (optical, magnetic, electronic, vibrational) properties of isolated nanocrystals remain present in addition to the intrinsic and collective properties. This allows to benefit from the unique properties of nanocrystals while avoiding their potential size-related risks in future applications. Metal Nano 3D Superlattices offers a deep dive into their synthesis, chemical and physical properties, and applications and is an essential resource for inorganic chemists, materials scientists, physical chemists, surface chemists, and medicinal chemists conducting research related to or involved in the practical application of the topics covered within.

Provides a broad and accessible introduction to the field of aerospace engineering, ideal for semester-long courses Aerospace engineering, the field of engineering focused on the development of aircraft and spacecraft, is taught at universities in both dedicated aerospace engineering programs as well as in wider mechanical engineering curriculums around the world-yet accessible introductory textbooks covering all essential areas of the subject are rare. Filling this significant gap in the market, Introduction to Aerospace Engineering: Basic Principles of Flight provides beginning students with a strong foundational knowledge of the key concepts they will further explore as they advance through their studies. Designed to align with the curriculum of a single-semester course, this comprehensive textbook offers a student-friendly presentation that combines the theoretical and practical aspects of aerospace engineering. Clear and concise chapters cover the laws of aerodynamics, pressure, and atmospheric modeling, aircraft configurations, the forces of flight, stability and control, rockets, propulsion, and more. Detailed illustrations, well-defined equations, end-of-chapter summaries, and ample review questions throughout the text ensure students understand the core topics of aerodynamics, propulsion, flight mechanics, and aircraft performance. Drawn from the author's thirty years' experience teaching the subject to countless numbers of university students, this much-needed textbook: Explains basic vocabulary and fundamental aerodynamic concepts Describes aircraft configurations, low-speed aerofoils, high-lift devices, and rockets Covers essential topics including thrust, propulsion, performance, maneuvers, and stability and control Introduces each topic in a concise and straightforward manner as students are guided through progressively more advanced material Includes access to companion website containing a solutions manual and lecture slides for instructors Introduction to Aerospace Engineering: Basic Principles of Flight is the perfect "one stop" textbook for instructors, undergraduates, and graduate students in Introduction to Aerospace Engineering or Introduction to Flight courses in Aerospace Engineering or Mechanical Engineering programs.

Covers computational methods in design and fluid dynamics with a focus on computational fluid dynamics Explains advanced material applications and manufacturing in labs using novel alloys and introduces properties in material Discusses fabrication of graphene reinforced magnesium metal matrix for orthopedic applications Illustrates simulation and optimization gear transmission, heat sink and heat exchangers application Provides unique problem-solution approach including solutions, methodology, experimental setup, and results validation

Helps engineers and scientists assess and manage uncertainty at all stages of experimentation and validation of simulations Fully updated from its previous edition, Experimentation, Validation, and Uncertainty Analysis for Engineers, Fourth Edition includes expanded coverage and new examples of applying the Monte Carlo Method (MCM) in performing uncertainty analyses. Presenting the current, internationally accepted methodology from ISO, ANSI, and ASME standards for propagating uncertainties using both the MCM and the Taylor Series Method (TSM), it provides a logical approach to experimentation and validation through the application of uncertainty analysis in the planning, design, construction, debugging, execution, data analysis, and reporting phases of experimental and validation programs. It also illustrates how to use a spreadsheet approach to apply the MCM and the TSM, based on the authors' experience in applying uncertainty analysis in complex, large-scale testing of real engineering systems. Experimentation, Validation, and Uncertainty Analysis for Engineers, Fourth Edition includes examples throughout, contains end of chapter problems, and is accompanied by the authors' website www.uncertainty-analysis.com. Guides readers through all aspects of experimentation, validation, and uncertainty analysis Emphasizes the use of the Monte Carlo Method in performing uncertainty analysis Includes complete new examples throughout Features workable problems at the end of chapters Experimentation, Validation, and Uncertainty Analysis for Engineers, Fourth Edition is an ideal text and guide for researchers, engineers, and graduate and senior undergraduate students in engineering and science disciplines. Knowledge of the material in this Fourth Edition is a must for those involved in executing or managing experimental programs or validating models and simulations.

A practical and accessible introductory textbook that enables engineering students to design and optimize typical thermofluid systems Engineering Design and Optimization of Thermofluid Systems is designed to help students and professionals alike understand the design and optimization techniques used to create complex engineering systems that incorporate heat transfer, thermodynamics, fluid dynamics, and mass transfer. Designed for thermal systems design courses, this comprehensive textbook covers thermofluid theory, practical applications, and established techniques for improved performance, efficiency, and economy of thermofluid systems. Students gain a solid understanding of best practices for the design of pumps, compressors, heat exchangers, HVAC systems, power generation systems, and more. Covering the material using a pragmatic, student-friendly approach, the text begins by introducing design, optimization, and engineering economics--with emphasis on the importance of engineering optimization in maximizing efficiency and minimizing cost. Subsequent chapters review representative thermofluid systems and devices and discuss basic mathematical models for describing thermofluid systems. Moving on to system simulation, students work with the classical calculus method, the Lagrange multiplier, canonical search methods, and geometric programming. Throughout the text, examples and practice problems integrate emerging industry technologies to show students how key concepts are applied in the real world. This well-balanced textbook: Integrates underlying thermofluid principles, the fundamentals of engineering design, and a variety of optimization methods Covers optimization techniques alongside thermofluid system theory Provides readers best practices to follow on-the-job when designing thermofluid systems Contains numerous tables, figures, examples, and problem sets Emphasizing optimization techniques more than any other thermofluid system textbook available, Engineering Design and Optimization of Thermofluid Systems is the ideal textbook for upper-level undergraduate and graduate students and instructors in thermal systems design courses, and a valuable reference for professional mechanical engineers and researchers in the field.

Fundamentals of Heat Exchanger Design, Second Edition builds upon the widely-used First Edition, a text often considered to be the most prominent single-volume heat exchanger text on the market. The new and improved Second Edition serves as an equally comprehensive resource, updated to suit the latest technologies and design methods being used in the Heat Exchanger field. Written by First-Edition author Dusan P. Sekulic, this text addresses the latest developments in the industry, including a brand-new chapter on the manufacturing of compact heat exchangers. After opening with a basic introduction to heat exchanger types and design methods, the book goes on to cover more specialized topics such as such as the design of recuperators and regenerators, pressure drop analysis, geometric properties, flow friction, fouling and corrosion, and more. With many significant revisions throughout, this new edition offers more streamlined content while maintaining the consistent, detailed coverage of the fundamentals of the topic that readers appreciated in the First Edition. These unique features position the Second Edition of Fundamentals of Heat Exchanger Design as the ideal text for both engineering professionals and advanced students alike.

This self-tutorial offers a concise yet thorough introduction into the mathematical analysis of approximation methods for partial differential equation. A particular emphasis is put on finite element methods. The unique approach first summarizes and outlines the finite-element mathematics in general and then in the second and major part, formulates problem examples that clearly demonstrate the techniques of functional analysis via numerous and diverse exercises. The solutions of the problems are given directly afterwards. Using this approach, the author motivates and encourages the reader to actively acquire the knowledge of finite- element methods instead of passively absorbing the material as in most standard textbooks. This English edition is based on the Finite Element Methods for Engineering Sciences by Joel Chaskalovic.

This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Volume 59 continues to report recent advances with a significant, up-to-date selection of contributions by internationally-recognized researchers.

The chapters of this volume are devoted to the following topics: - Iron Catalysis in Synthetic Chemistry- A New Paradigm for Photodynamic Therapy Drug Design: Multifunctional, Supramolecular DNA Photomodification Agents Featuring Ru(II)/Os(II) Light Absorbers Coupled to Pt(II) or Rh(III) Bioactive Sites- Selective Binding of Zn2+ Complexes to Non-Canonical Thymine or Uracil in DNA or RNA.- Progress Toward the Electrocatalytic Production of Liquid Fuels from Carbon Dioxide- Monomeric Dinitrosyl Iron Complexes: Synthesis and Reactivity- Interactions of Nitrosoalkanes/arenes, Nitrosamines, Nitrosothiols, and Alkyl Nitrites with Metals- Aminopyridine Iron and Manganese Complexes as Molecular Catalysts for Challenging Oxidative Transformations

Fundamentals of Engineering Programming with C and Fortran, first published in 1998, is a beginner's guide to problem solving with computers which shows how to quickly prototype a program for a particular engineering application. The book's side by side coverage of C and Fortran, the predominant computer languages in engineering, is unique. It emphasizes the importance of developing programming skills in C while carefully presenting the importance of maintaining a good reading knowledge of Fortran. Beginning with a brief description of computer architecture, the book then covers the fundamentals of computer programming for problem solving. It devotes separate chapters to data types and operators, control flow, type conversion, arrays, and file operations. The final chapter contains case studies that illustrate particular elements of modeling and visualization. Also included are a number of appendices covering C and Fortran language summaries and other useful topics. This concise and accessible book can be used as a text for introductory-level undergraduate courses on engineering programming or as a self-study guide for practising engineers.

This in-depth treatment of the instrumentation, physical bases and applications of x-ray photoelectron spectroscopy (XPS) and static secondary ion mass spectroscopy (SSIMS) contains a specific focus on the subject of polymeric materials. XPS and SSIMS are widely accepted as the two most powerful techniques for polymer surface chemical analysis, particularly in the context of industrial research and problem solving. The author describes the techniques and applications of XPS and SSIMS. He also includes details of case studies, emphasizing the complementary and joint application of XPS and SSIMS in the investigation of polymer surface structure and its relationship to the properties of the material. This book will be of value to academic and industrial researchers interested in polymer surfaces and surface analysis.

This book offers a brief, practically complete, and relatively simple introduction to functional analysis. It also illustrates the application of functional analytic methods to the science of continuum mechanics. Abstract but powerful mathematical notions are tightly interwoven with physical ideas in the treatment of nontrivial boundary value problems for mechanical objects.

This second edition includes more extended coverage of the classical andabstract portions of functional analysis. Taken together, the first three chapters now constitute a regular text on applied functional analysis. This potential use of the book is supported by a significantly extended set of exercises with hints and solutions. A new appendix, providing a convenient listing of essential inequalities and imbedding results, has been added.

The book should appeal to graduate students and researchers in physics, engineering, and applied mathematics.

Reviews of first edition:

"This book covers functional analysis and its applications to continuum mechanics. The presentation is concise but complete, and is intended for readers in continuum mechanics who wish to understand the mathematical underpinnings of the discipline. Detailed solutions of the exercises are provided in an appendix." (L Enseignment Mathematique, Vol. 49 (1-2), 2003)

"The reader comes away with a profound appreciation both of the physics and its importance, and of the beauty of the functional analytic method, which, in skillful hands, has the power to dissolve and clarify these difficult problems as peroxide does clotted blood. Numerous exercises test the reader s comprehension at every stage. Summing Up: Recommended." (F. E. J. Linton, Choice, September, 2003)

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Kristallgitter, Zustandsdiagramme, WArmebehandlung, StAhle, Nichteisenmetalle, Kunststoffe und Hochleistungskeramiken. Die Werkstoffkunde und die WerkstoffprA1/4fung sind vielseitig und anspruchsvoll. Passgenau auf den Bestseller "Werkstoffkunde und WerkstoffprA1/4fung fA1/4r Dummies" abgestimmt, A1/4ben Sie die wichtigen und schwierigen Themen. In bewAhrter Weise fA1/4hrt Sie Rainer Schwab durch ein intensives Training. Mit einfachen AufwArmA1/4bungen legen Sie los und steigern sich dann Schritt fA1/4r Schritt zu immer anspruchsvolleren Aufgaben. Mit fast 400 konkreten Fragestellungen samt ausfA1/4hrlichen LAsungen festigen Sie Ihr Wissen, viele Abbildungen sowie A1/4ber 500 Ankreuzaufgaben helfen Ihnen dabei. Sie gewinnen Sicherheit in den wichtigen Grundlagen und legen damit die Basis fA1/4r eine erfolgreiche PrA1/4fung.

Finite Element Analysis An updated and comprehensive review of the theoretical foundation of the finite element method The revised and updated second edition of Finite Element Analysis: Method, Verification, and Validation offers a comprehensive review of the theoretical foundations of the finite element method and highlights the fundamentals of solution verification, validation, and uncertainty quantification. Written by noted experts on the topic, the book covers the theoretical fundamentals as well as the algorithmic structure of the finite element method. The text contains numerous examples and helpful exercises that clearly illustrate the techniques and procedures needed for accurate estimation of the quantities of interest. In addition, the authors describe the technical requirements for the formulation and application of design rules. Designed as an accessible resource, the book has a companion website that contains a solutions manual, PowerPoint slides for instructors, and a link to finite element software. This important text: Offers a comprehensive review of the theoretical foundations of the finite element method Puts the focus on the fundamentals of solution verification, validation, and uncertainty quantification Presents the techniques and procedures of quality assurance in numerical solutions of mathematical problems Contains numerous examples and exercises Written for students in mechanical and civil engineering, analysts seeking professional certification, and applied mathematicians, Finite Element Analysis: Method, Verification, and Validation, Second Edition includes the tools, concepts, techniques, and procedures that help with an understanding of finite element analysis.

Metaheuristic optimization is a higher-level procedure or heuristic designed to find, generate, or select a heuristic (partial search algorithm) that may provide a sufficiently good solution to an optimization problem, especially with incomplete or imperfect information or limited computation capacity. This is usually applied when two or more objectives are to be optimized simultaneously. This book is presented with two major objectives. Firstly, it features chapters by eminent researchers in the field providing the readers about the current status of the subject. Secondly, algorithm-based optimization or advanced optimization techniques, which are applied to mostly non-engineering problems, are applied to engineering problems. This book will also serve as an aid to both research and industry. Usage of these methodologies would enable the improvement in engineering and manufacturing technology and support an organization in this era of low product life cycle. Features: Covers the application of recent and new algorithms Focuses on the development aspects such as including surrogate modeling, parallelization, game theory, and hybridization Presents the advances of engineering applications for both single-objective and multi-objective optimization problems Offers recent developments from a variety of engineering fields Discusses Optimization using Evolutionary Algorithms and Metaheuristics applications in engineering

The book "Nitride Semiconductor Technology" provides an overview of nitride semiconductors and their uses in optoelectronics and power electronics devices. It explains the physical properties of those materials as well as their growth methods. Their applications in high electron mobility transistors, vertical power devices, LEDs, laser diodes, and vertical-cavity surface-emitting lasers are discussed in detail. The book further examines reliability issues in these materials and puts forward perspectives of integrating them with 2D materials for novel high-frequency and high-power devices. In summary, it covers nitride semiconductor technology from materials to devices and provides the basis for further research.

Nanotechnology in Electronics Enables readers to understand and apply state-of-the-art concepts surrounding modern nanotechnology in electronics Nanotechnology in Electronics summarizes numerous research accomplishments in the field, covering novel materials for electronic applications (such as graphene, nanowires, and carbon nanotubes) and modern nanoelectronic devices (such as biosensors, optoelectronic devices, flexible electronics, nanoscale batteries, and nanogenerators) that are used in many different fields (such as sensor technology, energy generation, data storage and biomedicine). Edited by four highly qualified researchers and professionals in the field, other specific sample topics covered in Nanotechnology in Electronics include: Graphene-based nanoelectronics biosensors, including the history, properties, and fundamentals of graphene, plus fundamentals of graphene derivatives and the synthesis of graphene Zinc oxide piezoelectronic nanogenerators for low frequency applications, with an introduction to zinc oxide and zinc oxide piezoelectric nanogenerators Investigation of the hot junctionless mosfets, including an overview of the junctionless paradigm and a simulation framework of the hot carrier degradation Conductive nanomaterials for printed/flexible electronics application and metal oxide semiconductors for non-invasive diagnosis of breast cancer The fundamental aspects and applications of multiferroic-based spintronic devices and quartz tuning fork based nanosensors. Containing in-depth information on the topic and written intentionally to help with the practical application of concepts described within, Nanotechnology in Electronics is a must-have reference for materials scientists, electronics engineers, and engineering scientists who wish to understand and harness the state of the art in the field.

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems An indispensable compendium detailing the toxicology of nanoparticles with a focus on mechanisms, emerging issues, and new approaches Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems provides authoritative information on the toxicology of ultrafine and nanoparticulate matter that contaminate terrestrial or aquatic environments and present unique challenges in applied public health and toxicological research. Detailed chapters by a panel of world-renowned experts examine the complementary and dynamic interdependence of aquatic, terrestrial, and human systems and the toxicological impacts on exposure to engineered and manufactured nanoparticles and nanomaterials. Organized into four sections, the book opens with a thorough overview of the field, including known challenges and the necessity for current research activity. The second section describes terrestrial and aquatic systems and the ecotoxicological impact of nanomaterials, followed by critical analysis of the many human health effects of nanomaterials. The book concludes with an in-depth discussion of current gaps in knowledge, future directions, new approach methodologies, alternatives to animal models, and the emerging environmental threat from nanoplastics. Presenting case exemplars of the ecotoxicological impact of nanoparticles in aquatic and terrestrial systems, this important resource: Presents in-depth coverage of ecosafety, environmental behavior, fate and transport, interactive effects with other contaminants, and current challenges in soil nano-ecotoxicology Addresses rising concerns regarding air pollution and neurological disorders, and the roles played by the gastrointestinal system, the mucosal microbiome, and the immunotoxicology and vasculotoxicity of metal-based nanoparticles Provides detailed coverage of nanomaterial health effects from both animal and in vitro models, including the gut microbiome, innate immunity, neurological and cardiovascular impacts, mechanisms of action, and hazard characterization Analyzes key topics in ecological nanotoxicology such as environmental micro- and nano-plastic pollution and applied risk assessment Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems is essential reading for toxicologists, applied biologists, ecotoxicologists, research scientists, medical professionals, regulators, and advanced students in fields such as public health, environmental ecotoxicology and medicine, immunotoxicology, neurotoxicology, cardiovascular and systems biology, hazard identification, and risk assessment.

This book presents a systematic description of the electronic and physico-chemical properties of transition-metal carbides and nitrides. This is the first book devoted to the theoretical modelling of refractory carbides and nitrides and alloys based on them. It makes use of computational methods to calculate their spectroscopic, electric, magnetic, superconducting, thermodynamical and mechanical properties. Calculated results on the electronic band structure of ideal binary transition metal carbides and nitrides are presented, and the influence of crystal lattice defects, vacancies and impurities are studied in detail. Data available on chemical bonding and the properties of multi-component carbide- and nitride-based alloys, as well as their surface electronic structure, are described and compared with those of bulk crystals.

This text concentrates upon the mathematical theory of plasticity and fracture as opposed to the physical theory of these fields, and is presented in the thermomechanical framework. It follows the macroscopic, phenomenological approach which proposes equations abstracted from generally accepted experimental facts, studies the adequacy of the consequences drawn from these equations to those facts and then provides useful tools for designers and engineers. The material is drawn from the author's graduate course in Europe and the United States and may be used to form the basis for similar graduate courses on plasticity and fracture. Many worked examples are presented and each chapter concludes with problems for students. The book should thus undoubtedly establish itself as a core text for both students and researchers.

Provides a concise yet comprehensive introduction to XPS and AES techniques in surface analysis This accessible second edition of the bestselling book, An Introduction to Surface Analysis by XPS and AES, 2nd Edition explores the basic principles and applications of X-ray Photoelectron Spectroscopy (XPS) and Auger Electron Spectroscopy (AES) techniques. It starts with an examination of the basic concepts of electron spectroscopy and electron spectrometer design, followed by a qualitative and quantitative interpretation of the electron spectrum. Chapters examine recent innovations in instrument design and key applications in metallurgy, biomaterials, and electronics. Practical and concise, it includes compositional depth profiling; multi-technique analysis; and everything about samples--including their handling, preparation, stability, and more. Topics discussed in more depth include peak fitting, energy loss background analysis, multi-technique analysis, and multi-technique profiling. The book finishes with chapters on applications of electron spectroscopy in materials science and the comparison of XPS and AES with other analytical techniques. Extensively revised and updated with new material on NAPXPS, twin anode monochromators, gas cluster ion sources, valence band spectra, hydrogen detection, and quantification Explores key spectroscopic techniques in surface analysis Provides descriptions of latest instruments and techniques Includes a detailed glossary of key surface analysis terms Features an extensive bibliography of key references and additional reading Uses a non-theoretical style to appeal to industrial surface analysis sectors An Introduction to Surface Analysis by XPS and AES, 2nd Edition is an excellent introductory text for undergraduates, first-year postgraduates, and industrial users of XPS and AES.

In recent years, there have been significant developments in detector technologies in the field of astrophysics, requiring lower temperatures with simple self-contained refrigerators. Temperatures in the range of 1K to 50mK are now achieved by using dedicated closed-cycle miniature sorption coolers. This book presents the theoretical and experimental knowledge necessary to design and build your own miniature refrigerators, including both single shot and continuous 1 K, 300 mK and 100 mK coolers, and details how to write the needed design software. This text will be of interest to students and researchers, already familiar with basic physics and thermodynamics, who want to understand how sorption coolers and miniature dilution refrigerators work. Features: The first book dedicated to miniature sorption coolers Covers the basic thermodynamic concepts needed to understand the behavior of liquid helium-3 and liquid helium-4 Includes an appendix of Python example codes

"It’s about time that a practicing engineer with casting and academic experience has written a book that provides answers to questions about squeeze casting and semi-solid molding/forming that many engineers and students of casting need answered."

–Joseph C. Benedyk, PhD
Consultant and retired technical director, Alcoa

High Integrity Die Casting Processes provides a comprehensive look at the concepts behind advanced die casting technologies, including vacuum die casting, squeeze casting, and several variants of semi-solid metalworking. Practical applications for these processes are illustrated in numerous case studies.

This single-source reference tool presents the latest material in five sections:

• Basic concepts of die casting and molten metal flow
• High integrity die casting processes with case studies
• Product design considerations
• Controlling quality and avoiding defects
• Future advances under development

Key coverage includes a survey of liquid metal flow, strategies to overcome the limitations of conventional die casting, and potential defects unique to high integrity die casting processes. Also featured are methods for minimizing porosity, reducing cost by design, practical applied statistical process control techniques, designing for manufacturability, and containment methods for potential processing defects. Several chapters present detailed real-world examples illustrating the broad range of applications possible using high integrity die casting processes.

Included with this book is a CD-ROM containing PowerPoint presentations for each chapter. These presentations can be used for training purposes in conjunction with numerous study questions designed to practically apply the content of the book to real-world situations. Selected PowerPoint slides can be used to support engineering proposals, marketing presentations, or customer education seminars.

High Integrity Die Casting Processes is a valuable reference for both component producers and component users alike. Process engineers, tool designers, manufacturing engineers, production managers, and machine operators will acquire a better understanding of these advanced die casting processes to optimize manufacturing and improve product quality. Component designers, product engineers, purchasing agents, buyers, supplier quality engineers, and project managers will gain insight into these processes and develop superior products by design.

Provides a clear, concise, and self-contained introduction to Computational Fluid Dynamics (CFD) This comprehensively updated new edition covers the fundamental concepts and main methods of modern Computational Fluid Dynamics (CFD). With expert guidance and a wealth of useful techniques, the book offers a clear, concise, and accessible account of the essentials needed to perform and interpret a CFD analysis. The new edition adds a plethora of new information on such topics as the techniques of interpolation, finite volume discretization on unstructured grids, projection methods, and RANS turbulence modeling. The book has been thoroughly edited to improve clarity and to reflect the recent changes in the practice of CFD. It also features a large number of new end-of-chapter problems. All the attractive features that have contributed to the success of the first edition are retained by this version. The book remains an indispensable guide, which: Introduces CFD to students and working professionals in the areas of practical applications, such as mechanical, civil, chemical, biomedical, or environmental engineering Focuses on the needs of someone who wants to apply existing CFD software and understand how it works, rather than develop new codes Covers all the essential topics, from the basics of discretization to turbulence modeling and uncertainty analysis Discusses complex issues using simple worked examples and reinforces learning with problems Is accompanied by a website hosting lecture presentations and a solution manual Essential Computational Fluid Dynamics, Second Edition is an ideal textbook for senior undergraduate and graduate students taking their first course on CFD. It is also a useful reference for engineers and scientists working with CFD applications.