With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine.
The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.

Data fusion is a rapidly developing technology which involves the combination of information supplied by several NDT (Non-Destructive Testing) sensors to provide a more complete and understandable picture of structural integrity. This text is the first to be devoted exclusively to the concept of multisensor integration and data fusion applied to NDT. The advantages of this methodology are widely acknowledged and the author presents an excellent introduction to data fusion processes. Problems are approached progressively through detailed case studies, offering practical guidance for those wishing to develop and explore NDT data fusion further. This book will prove invaluable to inspectors, students and researchers concerned with NDT signal processing measurements and testing. It shows the great value and major benefits which can be achieved by implementing multisensor data fusion, not only in NDT but also in any discipline where measurements and testing are key activities.

This book deals with theoretical aspects of modelling the mechanical behaviour of manufacturing, processing, transportation or other systems in which the processed or supporting material is travelling through the system. Examples of such applications include paper making, transmission cables, band saws, printing presses, manufacturing of plastic films and sheets, and extrusion of aluminium foil, textiles and other materials.

The work focuses on out-of-plane dynamics and stability analysis for isotropic and orthotropic travelling elastic and viscoelastic materials, with and without fluid-structure interaction, using analytical and semi-analytical approaches. Also topics such as fracturing and fatigue are discussed in the context of moving materials. The last part of the book deals with optimization problems involving physical constraints arising from the stability and fatigue analyses, including uncertainties in the parameters.

The book is intended for researchers and specialists in the field, providing a view of the mechanics of axially moving materials. It can also be used as a textbook for advanced courses on this specific topic. Considering topics related to manufacturing and processing, the book can also be applied in industrial mathematics.
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The study of multiphase flows is of utmost interest for engineers who are more or less inevitably faced with them when handling various industrial processes or when dealing with environmental problems such as the dispersion of pollutants. It is also a large kingdom assembling many beautiful and weird landscapes in which wandering researchers may be caught by the fascination of precious stones or mysterious insets to deep and obscure caverns. Unfortunately, it is also an historically disconnected field of research, as testified by any textbook contents or by the scientific programs of conferences devoted to multiphase flows. For instance, is there a relation between fluidization and the study of interfacial waves, or between the behaviour of an annular film of liquid and the one of a free surface heated from below? The answer is indeed: yes. To help reveal some unity behind the avatars of multiphase flow behaviours, it has been decided to focus the interest on the instability phenomena. This book therefore provides the reader with most of the papers which have been accepted and/or presented at the international symposium on "instabilities in multiphase flows" held at the National Institute for Applied Science (INS A) in Rouen, France, from the 11 th of May to the 14th of May 1992. The topic of the conference has produced a strong emphasis on instability theory and nonlinear dynamics, including chaotic phenomena.

The title provides a comprehensive study of the slitting method for residual stress measurement, including analysis, computation, measurement, and estimation. It discusses different roles of residual stresses from the fracture mechanics perspective. Since its initial development in mid-1980, the slitting method has found increasing applications in many configurations that would be very difficult for traditional techniques. This work introduces students to the concepts of residual stresses and their measurement with examples and provides engineers with detailed procedures in computation and experiment for implementing methods. Researchers will also benefit from the detailed coverage of the elements of the analysis and computation.

This volume contains a selection of papers whose content have been presented at the International conferences CIPHI on Cultural Heritage and History of Engineering at University of Las Palmas de Gran Canaria in the Canary Islands, Spain, in recent years. The conference series is aimed at bringing together researchers, scholars and students from a broad range of disciplines referring to the History of Engineering and Cultural Heritage, in a unique multidisciplinary forum to stimulate collaboration among historians, architects, restaurateurs, and engineers.

These papers illustrate, by treating specific emblematic topics and problems, technical developments in the historical evolution of engineering concerning cultural heritage. Thus, emphasis is given to a discussion of matters of cultural heritage with engineering history by reporting authors' experiences and views. Topics treated include: reutilization of industrial heritage: the unique example of the Royal Segovia Mint in Spain; the image of factories; Pedro Juan De Lastanosa and "the twenty-one books of devices and machines of Juanelo"; the historical development of paper-mills and their machines in South Latium during 19th century; a virtual reconstruction of a wave-powered flour mill from 1801; 3D modelling and animation study of the industrial heritage wonders; a new model of the hydraulic machine known as "el artificio de Juanelo"; and the mystery of one Havana portrait, on the first steam machine in Cuba. This work has been made possible thanks to the invited authors who have enthusiastically shared this initiative and who have spent time and effort in preparing the papers in much more detail that in the conference presentations."

Eine pragnante, gut strukturierte Einfuhrung in die Anwendungen von DFT-Berechnungen In der neu uberarbeiteten zweiten Auflage von Density Functional Theory: A Practical Introduction liefern die Autoren eine pragnante und leicht verstandliche Einfuhrung in die wichtigsten Konzepte und praktischen Anwendungen der Dichtefunktionaltheorie (DFT), wobei der Schwerpunkt auf die DFT der ebenen Wellen gelegt wird. Die Autoren, die uber jahrzehntelange Erfahrung auf diesem Gebiet verfugen, bieten Studierenden mit unterschiedlichen Vorkenntnissen ein ausgewogenes Mass an Verstandlichkeit und Klarheit und haben auf diese Weise ein insgesamt sehr gut zu verstehendes Fachbuch verfasst. * In dieser neuen Auflage werden die Genauigkeit von DFT-Berechnungen und die Wahl der Funktionale detailliert eroertert * Das Werk bietet einen UEberblick uber ein breites Spektrum an verfugbaren DFT-Codes * Mit zusatzlichen Beispielen zur Nutzung von DFT fur Berechnungen von Materialien mit hohem Durchsatz * Starkere Hervorhebung der Berechnung von Phasendiagrammen und offener Ensemble-Methoden, die in der Elektrochemie umfassend genutzt werden. * In dieser erweiterten Auflage werden auch Berechnungen abgedeckt, die uber die Standard-DFT hinausgehen, z. B. DFT mit Dispersionskorrektur, DFT+U und zeitabhangige DFT

Since 1974, Viscous Fluid Flow has been known for its academic rigor and effectiveness at serving as a convenient "one-stop shop" for those interested in expanding their knowledge of the rich and evolving field of fluid mechanics. The fourth edition contains important updates and over 200 new references while maintaining the tradition of fulfilling the role of a senior or first-year graduate textbook on viscous motion with a well-balanced mix of engineering applications. Students are expected to understand the basic foundations of fluid mechanics, vector calculus, partial differential equations, and rudimentary numerical analysis. The material can be selectively presented in a one-semester course or, with more extensive coverage, in two (or even three) semesters.

An exposition of the derivation and use of equations of motion for two-phase flow. The approach taken derives the equations of motion using ensemble averaging, and compares them with those derived from control volume methods. Closure for dispersed flows is discussed, and some fundamental solutions are given. The work focuses on the fundamental aspects of two-phase flow, and is intended to give the reader a background for understanding the dynamics as well as a system of equations that can be used in predictions of the behavior of dispersed two-phase flows. The exposition in terms of ensemble averaging is new, and combining it with modern continuum mechanics concepts makes this book unique. Intended for engineering, mathematics and physics researchers and advanced graduate students working in the field.

A lot of recent developments have been made about adhesively bonded joints modeling using various methods of analysis. The increasing application of adhesives in industry is partly due to the increased sophistication and reliability of adhesive joints modeling. The book proposed intends to provide the designer with the most advanced stress analyses techniques in adhesive joints to reinforce the use of this promising bonding technique.

Contact mechanics was and is an important branch in mechanics which covers a broad field of theoretical, numerical and experimental investigations. In this carefully edited book the reader will obtain a state-of-the-art overview on formulation, mathematical analysis and numerical solution procedures of contact problems. The contributions collected in this volume summarize the lectures presented during the 4th Contact Mechanics Interantional symposium (CMIS) held in Hannover, Germany, 2005, by leading scientists in the area of contact mechanics.

This book is the first to deal with the important topic of the fire behaviour of fibre reinforced polymer composite materials. The book covers all of the key issues on the behaviour of composites in a fire. Also covered are fire protection materials for composites, fire properties of nanocomposites, fire safety regulations and standards, fire test methods, and health hazards from burning composites.

This book presents results of experimental and theoretical studies of "gas-solid particles" turbulent two-phase flows. It analyzes the characteristics of heterogeneous flows in channels (pipes), as well as those in the vicinity of the critical points of bodies subjected to flow and in the boundary layer developing on their surface. Coverage also treats in detail problems of physical simulation of turbulent gas flows which carry solid particles.

The European Turbulence Conferences have been organized under the auspices of the European Mechanics Committee (Euromech) to provide a forum for discussion and exchange of recent and new results in the field of turbulence. The first conference was organized in Lyon in 1986 with 152 participants. The second and third conferences were held in Berlin (1988) and Stockholm (1990) with 165 and 172 participants respectively. The fourth was organized in Delft from 30 June to 3 July 1992 by the J.M. Burgers Centre. There were 214 participants from 22 countries. This steadily growing number of participants demonstrates both the success and need for this type of conference. The main topics of the Fourth European Turbulence Conference were: Dynamical Systems and Transition; Statistical Physics and Turbulence; Experiments and Novel Experimental Techniques; Particles and Bubbles in Turbulence; Simulation Methods; Coherent Structures; Turbulence Modelling and Compressibility Effects. In addition a special session was held on the subject of CeBular Automata. Each of the sessions was introduced with a survey lecture. The lecturers were: W. Eckhaus, AJ. Libchaber, L. Katgerman, F. Durst, M. Lesieur, B. Legras, D.G. Dritschel and P. Bradshaw. The contributions of the participants were subdivided into oral and poster presentations. In addition to the normal program, some Speciai Interest Groups of Ercoftac (European Research Community on Flow, Turbulence and Combustion) presented their research activities in the form of a poster.

An In-Depth Resource for Understanding the Foundational Concepts and Clinical Applications in the Field of Biomechanics Winter's Biomechanics and Motor Control of Human Movement is highly suitable as a textbook for today's biomechanics students who may come from many diverse academic programs and professional sectors. The work covers foundational theoretical and mathematical concepts in biomechanics, as well as up-to-date data collection, interpretation, and storage techniques. It also highlights the contemporary clinical applications of biomechanical research. New case studies related to cerebral palsy, patellar femoral pain syndrome, knee osteoarthritis, and ulnar collateral ligament reconstruction are also included. The work appeals to a broad audience within the field of biomechanics, an interdisciplinary field with applications in mechanical engineering, medicine, physical therapy, sports and exercise, and product development. Authors at leading universities guide the reader through the latest advancements in the field while also imparting critical foundational knowledge to allow for subject matter mastery and more precise practical application. Concepts covered in the book include: Biomechanical signal processing, anthropometry, kinematics and kinetics, muscle mechanics, and kinesiological electromyography Forward simulations and muscle-actuated simulations, static and dynamic balance, and the role of the central nervous system in biomechanics Movement sequencing and the kinetic chain concept, electromagnetic systems, inertial sensors, clinical measures of kinematics, and the advantages and disadvantages of different types of force plates Markerset design and event detection for gait and athletic motions like jumping, landing, and pitching Guidance on setting up a motion lab and access to online Excel spreadsheets with kinematic and kinetic marker data By providing a combination of theoretical and practical knowledge, Winter's Biomechanics and Motor Control of Human Movement will appeal to biomedical engineers working in the field of biomechanics and allied professionals in the medical, rehabilitation, and sports industries. Its comprehensive overall insight into the field of biomechanics also makes the work a highly useful resource for students and teachers of biomechanics at all levels of experience and expertise.

The frozen-hydrated specimen is the principal element that unifies the subject of low temperature microscopy, and frozen-hydrated specimens are what this book is all about. Freezing the sample as quickly as possible and then further preparing the specimen for microscopy or microanalysis, whether still embedded in ice or not: there seem to be as many variations on this theme as there are creative scientists with problems of structure and composition to investigate. Yet all share a body of com mon fact and theory upon which their work must be based. Low-Temperature Micros copy and Analysis provides, for the first time, a comprehensive treatment of all the elements to which one needs access. What is the appeal behind the use of frozen-hydrated specimens for biological electron microscopy, and why is it so important that such a book should now have been written? If one cannot observe dynamic events as they are in progress, rapid specimen freezing at least offers the possibility to trap structures, organelles, macro molecules, or ions and other solutes in a form that is identical to what the native structure was like at the moment of trapping. The pursuit of this ideal becomes all the more necessary in electron microscopy because of the enormous increase in resolution that is available with electron-optical instruments, compared to light optical microscopes."

Probabilistic risk and hazard assessments are applied to a wide range of engineering systems, mainly for regulatory reasons needed for development consent, system certification and occupational health and safety issues. The purpose of this book is to raise awareness of the limitations, uncertainties and other issues inherent in probabilistic risk analysis procedures. Probabilistic Risk Assessment of Engineering Systems describes: the importance of probabilistic risk assessment in decision making, i.e. risk management; types of risk and probabilistic risk analysis procedures; data needed for the conduct of probabilistic risk analysis; and acceptable/tolerable risk and other risk acceptance criteria. In essence, the book provides a multi-disciplinary and integrated explanation of risk assessment procedures that will enable the non-specialist reader to gain valuable insights into the development of risk analysis procedures. Practising engineers and graduate engineering students across a range of disciplines will find this book immensely useful.

High-speed impact dynamics is of interest in the fundamental sciences, e.g., astrophysics and space sciences, and has a number of important applications in military technologies, homeland security and engineering. When compared with experiments or numerical simulations, analytical approaches in impact mechanics only seldom yield useful results. However, when successful, analytical approaches allow us to determine general laws that are not only important in themselves but also serve as benchmarks for subsequent numerical simulations and experiments. The main goal of this monograph is to demonstrate the potential and effectiveness of analytical methods in applied high-speed penetration mechanics for two classes of problem. The first class of problem is shape optimization of impactors penetrating into ductile, concrete and some composite media. The second class of problem comprises investigation of ballistic properties and optimization of multi-layered shields, including spaced and two-component ceramic shields. Despite the massive use of mathematical techniques, the obtained results have a clear engineering meaning and are presented in an easy-to-use form. One of the chapters is devoted solely to some common approximate models, and this is the first time that a comprehensive description of the localized impactor/medium interaction approach is given. In the monograph the authors present systematically their theoretical results in the field of high-speed impact dynamics obtained during the last decade which only partially appeared in scientific journals and conferences proceedings.

Beatrice Bressan brings together a number of outstanding examples of successful cross-disciplinary technology transfer originating in fundamental physics research, which dramatically impacted scientific progress in areas which changed modern society. Many of them were developed at CERN, a hotbed of fundamental inventions in particle physics. This book deals with breakthrough developments being applied in the world of IT, consumer electronics, aviation, and material sciences. Additional sections of the book deal with knowledge management and technology transfer including their economic aspects. While each chapter has been drafted by an expert in the field, the editor has carefully edited the whole to ensure a coherent overall structure. A must-have for policy makers, technology companies, investors, strategic planners in research and technology, as well as attractive reading for the research community.

"The book provides vital insights into commercial development for engineering students in a highly practical and applied manner. Over the past 3 years, application of the book s material has allowed the students to develop their commercial literacy and ambition in the University." Steve Orr, Director, Northern Ireland Science Park CONNECT program which looks to accelerate the growth of knowledge-based companies in Northern Ireland Engineering Innovative Products: A Practical Experience is a pioneering book that will be of key use to senior undergraduate and graduate engineering students who are being encouraged to explore innovation and commercialization as part of their courses. The book will teach the essential skills of entrepreneurship and address the fundamental requirements needed to establish a successful technology company. As well as providing the crucial background and insights enabling students to identify a key market, it also offers a highly practical guide to undertaking genuine product validation and producing a feasibility study, as well as providing vital insights into the challenges and demands in forming a technology based company. Key features: * Outlines how to develop and grow an engineering solution which has market potential and covers key business aspects of giving the perfect pitch, sales and marketing, protection of ideas and finance, to offer a complete and practical guide to commercializing ideas. * Provides vital insight into the design and innovation processes within engineering and the challenges and pitfalls in translating good ideas into great products. * Features contributions from leading experts in marketing, finance, company formation, sales and intellectual protection which provides details of the challenges faced by innovators when commercializing ideas. * Includes Ccase studies from engineering students who give insights into how they have successfully developed their own ideas into companies.

Understanding the physical and thermomechanical response of materials subjected to intensive dynamic loading is a challenge of great significance in engineering today. This volume assumes the task of gathering both experimental and diagnostic methods in one place, since not much information has been previously disseminated in the scientific literature.

This book serves as an introduction to magnetohydrodynamics (MHD) for graduate and advanced undergraduate engineering students. It may be used by engineers and physicists in research institutions and industry to become familiar with the particular phenomena of magnetothermohydraulics in technical liquid metal flows influenced by magnetic fields. The starting point of the book is the outcome of a recent nuclear fusion project. Therefore, it contains many new results that can be utilized for the design and optimization of various technical systems and processes.

Human factors, also known as human engineering or human factors engineering, is the application of behavioral and biological sciences to the design of machines and human-machine systems. Automation refers to the mechanization and integration of the sensing of environmental variables, data processing and decision making and mechanical action. This book deals with all the issues involved in human-automation systems from design to control and performance of both humans and machines.

This book contains contributions by colleagues, former students and friends of Professor Eli Reshotko in celebration of his 60th birth day. Since Professor Reshotko's scientific and engineering contribu tions have been in the areas of hydrodynamic stability, transition to turbulence, and boundary layer flows, it is only appropriate that the articles in this volume be devoted to these and related topics. The first two sections focus on instabilities and transition in sub sonic and supersonic flows, respectively. The third section deals with developing turbulence, while the the final section treats related prob lems in engineering fluid mechanics. The diversity and scope of the articles contained herein exemplify the insight and expertise required in the study of transitional and turbulent flows today - traits which also exemplify Eli Reshotko's contributions to these fields. A few of the articles in this volume were presented at a sym posium in honor of Eli Reshotko's 60th birthday, held in Newport News, Virginia, on July 28, 1991. The symposium was sponsored by lCASE, and organized by M.Y. Hussaini (lCASE) and R. Hirsh (U.S. National Science Foundation). Of those who could not attend, many chose to honor Professor Reshotko by a contribution to the volume dedicated to him. We would like to use this opportunity to express our deep ap preciation to M.Y. Hussaini for initiating this very special tribute to Eli, and to Ms. Emily Todd for her efforts in the volume preparation and in the organization of the symposium."

Micromechanical manufacturing based on microequipment creates new possibi- ties in goods production. If microequipment sizes are comparable to the sizes of the microdevices to be produced, it is possible to decrease the cost of production drastically. The main components of the production cost - material, energy, space consumption, equipment, and maintenance - decrease with the scaling down of equipment sizes. To obtain really inexpensive production, labor costs must be reduced to almost zero. For this purpose, fully automated microfactories will be developed. To create fully automated microfactories, we propose using arti?cial neural networks having different structures. The simplest perceptron-like neural network can be used at the lowest levels of microfactory control systems. Adaptive Critic Design, based on neural network models of the microfactory objects, can be used for manufacturing process optimization, while associative-projective neural n- works and networks like ART could be used for the highest levels of control systems. We have examined the performance of different neural networks in traditional image recognition tasks and in problems that appear in micromechanical manufacturing. We and our colleagues also have developed an approach to mic- equipment creation in the form of sequential generations. Each subsequent gene- tion must be of a smaller size than the previous ones and must be made by previous generations. Prototypes of ?rst-generation microequipment have been developed and assessed.