The Basic Bookshelf for Eyecare Professionals is a series that provides fundamental and advanced material with a clinical approach to clinicians and students. A special effort was made to cover information needed for the certification exams in ophthalmic and optometric assisting, low vision, surgical assisting, opticianry, and contact lens examiners. General Medical Knowledge is designed for those needing to learn or brush up on the anatomy and physiology of the human body. This book emphasizes the fact that the eye is part of the body as a whole and presents the basic concepts of anatomy and physiology as well as an overview of common diseases. The first section begins with cells and tissues, then discusses the various organ systems including cardiovascular, respiratory, endocrine, and nervous. The second section covers systemic diseases and disorders including connective tissue disease, age related disorders, and neoplastic disorders, with special emphasis on how each of these can affect the eye. This text will provide a solid foundation of general medical knowledge for those working as eyecare professionals.

Warum brauchen wir Schlaf? Wie entsteht Durst? Oder ein Herzinfarkt? In der Physiologie lernen Sie alles über die Funktionen des menschlichen Körpers. Die 32. Auflage der Physiologie des Menschen wurde komplett überarbeitet, der Stoff ist nun in 84 übersichtliche Kapitel gegliedert. Gleich die erste Seite eines Kapitels bietet einen hervorragenden Überblick über den Lernstoff: In einer Box wird kurz und knapp erklärt, worum es im Kapitel geht. Danach kommen die visuellen Lerner auf ihre Kosten: eine zusammenfassende Abbildung bringt das Wesentliche auf den Punkt. Beim Lernen und Wiederholen unterstützen Sie außerdem: Grüne Zwischenüberschriften – fassen die einzelnen Abschnitte in einem Satz zusammen, ideal zum Wiederholen! Rote Merksätze – machen auf besonders wichtige Inhalte aufmerksam Zusammenfassungen zu allen Abschnitten Fast 200 Klinikboxen – machen die klinischen Bezüge deutlich Über 1000 Abbildungen für das visuelle Lernen Interessante Hintergrundinformationen als Kleingedrucktes Nicht nur für die Vorklinik, auch im klinischen Abschnitt sind die physiologischen Zusammenhänge Grundlage, um Krankheiten und ihre Entstehung zu verstehen. Machen Sie den Brandes/Lang/Schmidt zu Ihrem Begleiter durch das gesamte Studium!

Written by nearly 60 of the world's leading investigators in this rapidly expanding field, this state-of-the-art reference furnishes detailed presentations on the basic science and clinical aspects of cilia, mucus, and mucociliary interactions. Providing stimulating coverage of the latest information in a single source, Cilia, Mucus, and Mucociliary Interactions -discusses the genetic determinants of mucociliary system structure and function -explains ciliary wave activity in cell-cell communication -elucidates many of the key physiological processes in ciliary regulation -reveals possible means of treating irregularities in mucus secretion and clearance -improves understanding of clinical syndromes, including abnormalities pertaining to nasal sinuses, upper and lower airways, and the systemic role of cilia -approaches the clinical management of mucociliary dysfunction logically using currently available diagnostic and therapeutic techniques -and much more! Containing bibliographic citations, tables, equations, drawings, and photographs, this exhaustive guide is essential reading for physiologists, pulmonologists, otolaryngologists, pediatricians, microbiologists, basic scientists, and graduate and medical school students in these disciplines.

"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."

Explore the science behind over 50 pilates exercises to master each movement with confidence and control. DK brings you a ground-breaking health book that will help you revitalise your workouts and perfect your Pilates practice, by understanding the muscle action, breathwork and techniques required, every step of the way. Did you know that performing Pilates can strengthen your core, improve flexibility and posture, and help to reduce stress and anxiety at the same time? Backed by scientific research, learn how Pilates exercises benefit every system in the body. Science of Pilates reveals the facts with annotated artworks that show the mechanics, the angles, how your blood flow and respiration are affected, the key muscle and joint actions working below the surface of each exercise, safe alignment, and much more! Go on a journey of self-discovery to explore: - Specially commissioned CGI artworks depict all the main Pilates exercises with variations that add or reduce challenge. - Artworks detail the mechanics of each exercise, correct body posture, the muscles involved and how they engage to perform movements. - Illustrations featuring colour-coding to highlight how the muscles, ligaments, and joints engage, stretch, and relax to perform each exercise. - Pilates programmes tailored to different abilities and aims. - Suggested practices with a progressive increase in challenge over weeks and months. - Easy-to-follow infographics help explain the hard science behind why Pilates training is so effective and what beneficial physical adaptations it can bring. Set out to unearth the facts behind the pseudo-science fads, The Science of Pilates is an approachable, entertaining and easy-to read fitness guide for those seeking self-development backed up by solid scientific evidence. The popular question and answer format brings an immediacy to the information provided, and the highly visually illustrations truly bring the science to life in a contemporary and accessible way. At DK, we believe in the power of discovery. So why stop there? If you like Science of Pilates, then why not try Science of Yoga to help you better understand yoga anatomy in order to perfect your practice and poses, or Science of Strength Training to support you in your journey to build you strongest body. Complete the collection today!

This book explores several subtypes of muscarinic receptors that modulate smooth muscle activity. Main topics include a classification of muscarinic receptors, biochemical responses that occur in smooth muscle, the role of muscarinic receptors in the function of gastrointestinal and genitourinary smooth muscle, and prejunctional muscarinic receptors in smooth muscle. Discussions cover the current state of research and are intended to generate further research into the design of novel therapeutics for disorders of smooth muscle function.

Sport, Recovery and Performance is a unique multi-disciplinary collection which examines both the psychological and physiological dimensions to recovery from sport. Including contributions from medicine, neuroscience, psychology and sport science, the book expertly explores the implications for applied and strategic interventions to both retain and stabilize performance, and promote health and well-being. Including chapters written by its leading experts, the book represents an important milestone in this evolving field of study. It covers issues around measuring recovery, the impact of overtraining on sleep and mental health, and addresses topics such as the impact of travel on performance. The book informs not only how managing recovery can improve performance, but also offers insights in how recovery can sustain athletes' physical and mental health. Citing research from a range of individual and team sports, as well as extreme situations and the workplace, this is an important book that will be widely read across the sport sciences.

This book explores the role calcium signaling plays in cellular responses in almost all types of cells including airway smooth muscle cells. This universal signaling may result from extracellular calcium influx and/or intracellular calcium release, which are precisely controlled and regulated by ion channels, exchangers and/or transporters on the plasmalemmal or sarcoplasmic reticulum membrane. First, several chapters detail calcium release channels (ryanodine receptors and inositol trisphosphate receptors), voltage-dependent potassium channels, transient receptor potential channels, Orai channels, calcium-activated potassium channels, and calcium-activated chloride channels. Well-characterized sodium-calcium exchangers, voltage-dependent calcium channels, and calcium pumps are described also in depth over many chapters.

Ca2+ signaling can be expressed in Ca2+ sparks, waves, oscillations, and global changes in intracellular Ca2+ concentration. Calcium in subcellular compartments (cytosol, sarcoplasmic reticulum, mitochondria, and caveolae) also exhibit dynamic crosstalk. Many molecules including FK506 binding proteins, cyclic adenosine diphosphate ribose, reactive oxygen species, RhoA kinases, caveolin and integrins can modify and induce spatial, temporal and compartmental variations of calcium signaling. In addition, calcium signaling can exhibit sex hormone- and age-dependent changes. A number of chapters are dedicated to covering these diverse formats, spatiotemporal characteristics, multifaceted network and mathematical modeling of Ca2+ signaling.

Neurotransmitters, hormones, growth factors, inflammatory cytokines, and other stimuli may lead to multiple cellular responses by inducing Ca2+ signaling in airway smooth muscle cells. Increasing evidence suggests that Ca2+ pumps and canonical transient receptor potential channels are essential for airway smooth muscle remodeling. Accordingly, several chapters summarize recent advances in the studies of the key role of calcium signaling in physiological cellular responses as well as the development of asthma, chronic obstructive pulmonary disease and other respiratory disorders.

Nutrition and Health: Topics and Controversies explores in detail the relationship between diet, nutritional status, and disease, and evaluates nutritional practices intended to minimize the incidence of and slow the progress of major chronic illnesses. National trends in nutritional awareness and the resulting changes in consumer behavior are discussed. Unlike other books on this subject, the authors take a stand on controversial issues in the field and document their positions with scientific data. Nutrients such as calcium, vitamin E, selenium, and antioxidants, their importance in overall nutrition, and their role in specific diseases are covered. Expertise in nutritional science is not required to gain the highly practical information in this book.

Introduction to Computational Cardiology provides a comprehensive, in-depth treatment of the fundamental concepts and research challenges involved in the mathematical modeling and computer simulation of dynamical processes in the heart, under normal and pathological conditions.

About this textbook:

- Presents descriptions of models used in both biology and medicine for discovering the mechanisms of heart function and dysfunction on several physiological scales across different species.

- Provides several examples throughout the textbook and exercises at the end which facilitate understanding of basic concepts and introduces, for implementation, treated problems to parallel supercomputers.

Introduction to Computational Cardiology serves as a secondary textbook or reference book for advanced-level students in computer science, electrical engineering, biomedical engineering, and cardiac electrophysiology. It is also suitable for researchers employing mathematical modeling and computer simulations of biomedical problems.

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists.
Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure.
Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.

The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject.
This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.

Although work furniture has had so much more attention recently there is a long way to go before this is translated into action in the wider world. Increased international concern for the health and safety of people at work is one of the driving forces behind this book.; The Science of Seating brings together researchers in ergonomics and posture with industrial designers, to review and assess the current state of chair design, with implications for cultural, behavioural and occupational aspects of health. The contributions are a significant step in the science of seating and should lead to a better understanding of the mechanics, dynamics and the effects of seating on the sitter.; They point to ways in which seats might become easier-to-use and adjust, offering both comfort and postural support without compromising freedom of movement: and in the not-too-distant furture, "the intelligent chair" will "remember" the sitter's preferences for position, cushiness and so on.; Topics covered include: Adjustability, Anthropometics, Posture, Back Pain, Biomechanics, Seat Pressure Distributions, School children, Special Needs of Users, Design Applications, Industry Perspectives, VDT Standards.; It is aimed at researchers and practising seating designers, ergonomists, design engineers, occupational health workers and physiotherapists and furniture manufacturers.

Whether you're a clinician concerned with patient management, a technician involved in diagnostic testing, or an investigator studying fibrinogen structure and function, you'll find that the 1994 Index of Variant Human Fibrinogens. is a valuable resource. It contains not only the most comprehensive compilation of the world literature and research on dyfibrinogenemia, but also includes a synopsis for health professionals and expert guidance for the diagnosis and treatment of dysfibrinogenemia, the study of genetically abnormal human fibrinogens. Furthermore, this book provides the latest DNA and protein sequences (including the AaE chain) and listings of available PCR primers and anti-fibrinogen antibodies. Add to this a set of 263 Dysfibrinogen Reports tracking more than 30 different characteristics for each variant, plus 9 summary tables and a comprehensive bibliography, and the result is an authoritative companion for the diagnosis and management of this multifaceted and complex disease.
Compare your patient's laboratory profile, clinical manifestations, or molecular defect with virtually all others in the literature. Consider all the options for treating bleeding or thrombotic complications. Determine if your data from a newly identified variant are unique. Spend an hour with this book and see if it doesn't save many hours of literature searching and summarizing

Audience
Applied biomathematicians, orthopedists, clinical orthopedists.

William Harvey (1578-1657) was a rebel in medical science: Contrary to contemporary practice, he began his epoch-making investigation into the action of the heart and the blood's circulation by minutely observing their action in live animals and by a lengthy series of dissections, rather than by mere reliance on the anatomical lessons of ancient medicine and philosophy. "On the Motion of the Heart and Blood in Animals", including explanations of heart valves and arterial pulse, stands as a triumph of true scientific inquiry, and is still regarded as one of the greatest discoveries in physiology.

This reference work brings together the biology, mechanics, neurophysiology and pathophysiology of diseased joints, illustrates available physiologically-based treatments for osteoarthrosis and explains how and when to use them.;Highlighting the most up-to-date biomechanical principles, Mechanics of Human Joints: discusses the functional anatomy of joints; relates the neurophysiology of joints to ligamentous reconstruction; elucidates the pathophysiology of osteoarthrosis; summarizes the latest information on muscle physiology and electromyography; examines the effect of vibration and impulsive loading on joint pathology; and explicates the principles of prosthetic joint replacement.

Notes On Clinical Biochemistry shows how the details of molecular architecture and metabolic pathways which every biochemistry student has to learn can be summarised and made applicable to a wide range of clinical problems. This is done partly by a theoretical discussion of the links between the basic biochemistry and corresponding medical scenarios, and partly by the discussion of case histories. In this way, a very wide range of medical problems is discussed economically.This book is aimed at all those studying clinical chemistry, and medical students in the middle period of their course, that is the 2nd - 4th years. This is when the knowledge of basic sciences gained in the earlier period comes to be applied to clinical situations, and the book attempts to show, with respect to biochemistry, how this continuum is achieved.

The quality of life for millions of people all over the globe has been improved by the work of diligent biologists and doctors working in the many branches of life science. An improved knowledge of how the body functions at the genetic, cellular, physiological and behavioural levels and a greater understanding of disease and pharmacology have resulted in a reduction in human suffering. The way is being paved for the effective treatment of some of the greatest health problems of the late twentieth century - cancer, AIDS and diseases caused by parasites.These two volumes are collections of the Nobel Lectures delivered by the laureates, together with their biographies, portraits and the presentation speeches for the periods 1971 - 1980 and 1981 - 1990 respectively. Each Nobel Lecture is based on the work for which the laureate was awarded the prize. New biographical data of the laureate are also included. These volumes of inspiring lectures by outstanding scientists should be on the bookshelf of every keen student, teacher and professor of biological and medical sciences as well as of those in related fields.During the period 1971 - 1980 important areas of research being recognized were as diverse as hormone action and radioimmunoassays, infectious diseases, molecular genetics, immunology, computerized tomography and social behaviour. The laureates according to the specific year are:(1971) E W SUTHERLAND JR - for his discoveries concerning the mechanisms of the action of hormones; (1972) G M EDELMAN & R R PORTER - for their discoveries concerning the chemical structure of antibodies; (1973) K VON FRISCH, K LORENZ & N TINBERGEN - for their discoveries concerning organization and elicitation of individual and social behaviour patterns; (1974) A CLAUDE, C DE DUVE & G E PALADE - for their discoveries concerning the structural and functional organization of the cell; (1975) D BALTIMORE, R DULBECCO & H M TEMIN - for their discoveries concerning the interaction between tumour viruses and genetic material of the cell; (1976) B S BLUMBERG & D C GAJDUSEK - for their discoveries concerning new mechanisms for the origin and dissemination of infectious diseases; (1977) R GUILLEMIN & A V SCHALLY - for their discoveries concerning the peptide hormone production of the brain; and R S YALOW - for the development of radioimmunoassays of peptide hormones; (1978) W ARBER, D NATHANS & H O SMITH - for the discovery of restriction enzymes and their application to problems of molecular genetics; (1979) A M CORMACK & G N HOUNSFIELD - for the development of computer assisted tomography; (1980) B BENACERRAF, J DAUSSET & G D SNELL - for their discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions.

Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.

Biophysics is the science of physical principles underlying all processes of life, including the dynamics and kinetics of biological systems.

This fully revised 2nd English edition is an introductory text that spans all steps of biological organization, from the molecular, to the organism level, as well as influences of environmental factors. In response to the enormous progress recently made, especially in theoretical and molecular biophysics, the author has updated the text, integrating new results and developments concerning protein folding and dynamics, molecular aspects of membrane assembly and transport, noise-enhanced processes, and photo-biophysics. The advances made in theoretical biology in the last decade call for a fully new conception of the corresponding sections. Thus, the book provides the background needed for fundamental training in biophysics and, in addition, offers a great deal of advanced biophysical knowledge.

Pediatric arrhythmias present numerous challenges to pediatric cardiologists and other practitioners who see pediatric patients, including pediatricians, family physicians, emergency physicians, residents, fellows, and other clinicians. Arrhythmias in Children: A Case-Based Approach features practical methods for diagnosing and treating arrhythmias in these patients across all settings. Nearly three dozen real-world scenarios are presented, followed by a discussion of the diagnosis, clinical thinking process involved, treatment options, expected outcomes, and how to manage anticipated and unanticipated outcomes. These practical, realistic cases provide a unique and engaging way of approaching these challenging patient scenarios. Uses a case-based approach for a full spectrum of pediatric arrythmias in the newborn, child, pre-teen, and teenager. Presents history and physical, differential diagnoses, tests to order, and practical plans of action. Includes a section on arrythmias in special circumstances. Models clinical thinking skills for a wide number of real-world patient situations. Reviews pertinent clinical guidelines, treatment, and follow up.

Presented as a series of lectures, this important volume achieves four major goals:
1) It integrates the results of the author's research as applied to pattern perception -- reviewing current brain research and showing how several lines of inquiry have been converging to produce a paradigm shift in our understanding of the neural basis of figural perception.
2) It updates the holographic hypothesis of brain function in perception.
3) It emphasizes the fact that both distributed (holistic) and localized (structural) processes characterize brain function.
4) It portrays a neural systems analysis of brain organization in figural perception by computational models -- describing processing in terms of formalisms found useful in ordering data in 20th-century physical and engineering sciences.
The lectures are divided into three parts: a Prolegomenon outlining a theoretical framework for the presentation; Part I dealing with the configural aspects of perception; and Part II presenting its cognitive aspects. The appendices were developed in a collaborative effort by the author, Kunio Yasue, and Mari Jibu (both of Notre Dame Seishin University of Okayama, Japan).

This new volume gives a concise overview covering the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and model animals which one needs to understand to make independent contributions inthe research area of comparative medicine. During the writing process of the book the authors were in constant interdisciplinary dialogue. Theyaim to contribute to the improvement of quality of life for human and animal patients.

This volume is a record of the proceedings of a festspiel held to honor Jozef F. Zwislocki for his outstanding contributions to science and to Syracuse University. His contributions to the knowledge of the hydromechanical, neurophysiological, and perceptual mechanisms of the auditory system are truly monumental. In addition, his contributions to the comprehension of the mammalian auditory system include not only landmark ideas, but also many of the experimental findings in psychoacoustics and peripheral auditory physiology that constitute the database which has provided a springboard for research in laboratories throughout the world. His efforts to link physics, biology, and psychophysics to create a basis for our understanding of the nervous system have had an influence that extends far beyond the science of acoustics. Although the purpose of this conference was to recognize the many achievements of Professor Zwislocki, the spirit of the participants was to honor him in a manner that best characterized his lifetime dedication to research, that is, to report the results of their own work. Consequently, this volume is first and foremost a compilation of scientific papers in the area of sensory research. Some are reports of recent experiments and some present an overview of research efforts extending from the past up to ongoing work. His influence can be recognized in all of the contributions and some explicitly describe the ties between their own work and the germinal ideas planted by him. This volume, in reflecting the rapid progress being made in sensory science and written by those who are making it, is a fitting tribute to Zwislocki, who always stood at the forefront of his science.