Praise for the First Edition

" . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."--Zentralblatt MATH

A new edition of the cutting-edge guide to diagnostic tests in medical research

In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations.

Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include:

Methods for tests designed to detect and locate lesions

Recommendations for covariate-adjustment

Methods for estimating and comparing predictive values and sample size calculations

Correcting techniques for verification and imperfect standard biases

Sample size calculation for multiple reader studies when pilot data are available

Updated meta-analysis methods, now incorporating random effects

Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS(R), and R software packages so that readers can conduct their own analyses.

Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

Updated with new treatments and algorithms, ECG Facts Made Incredibly Quick! Second Edition provides instant access to information that every nurse needs for safe patient care. The book fits comfortably into a pocket, and the wipeable page surface allows nurses to write notes and remove them easily. Coverage includes basic electrocardiography including cardiac conduction, lead placement, and heart rate calculation; rhythm strip interpretation; causes, signs and symptoms, interventions, and treatment for arrhythmias; 12-lead and 15-lead ECG interpretation; ECG changes with angina, MI, pericarditis, and bundle branch block; and antiarrhythmic drugs, pacemakers, and ICDs. Scores of ECG waveforms, treatment algorithms, and charts are included. Distinctive-colored tabs identify each section.

Domestic Violence/Strangulation Assessment will teach readers the language of evidence-based evaluative methods of care for strangulation patients. It is designed to standardize anatomic nomenclature, as it relates to the head and neck, for both new and experienced sexual assault nurse examiners (SANEs) and sexual assault forensic examiners (SAFEs), first responders, medical residents and physicians, nursing students, and nurse practitioners, including nurse midwives, women's health nurse practitioners, pediatric nurse practitioners, and forensic nurse practitioners. Ten new strangulation case studies with a clear history, photographic representation, and confirmation of anatomic landmarks and injuries, along with discussions about existing conditions and their influence, identification of injury, evidence-based collection techniques, and treatment based on current standards of practice. Chapters will also include best practice recommendations and other tools to support evaluation and documentation. Offering this workbook to first responders and health care providers will help fulfill their need for basic, peer-reviewed information and will contribute to continuing competence in care for strangulation patients.

The Sexually Transmitted Infections and Sexually Transmitted Diseases workbook is a self-directed assessment for medical professionals to learn, apply, and demonstrate competency in the evaluation for sexually transmitted infections and diseases. Readers will have the opportunity to assess case histories and accompanying full-color photographs for reference. Each case history includes a series of evaluation exercises designed to refine and reinforce readers' skills in sexually transmitted infection identification, treatment recommendation, and follow-up care.