Pregnancy tests, HIV tests, and tests to confirm heart attacks and many other clinical diagnostic tests are all immunoassays. Without immunoassays a huge variety of biologically important molecules could not be easily detected or quantified. Immunoassays is the first practical volume designed to help any biologist develop an immunoassay of any common format for any suitable analyte. The basic principles are described and the choices of assay types and formats listed.

Since 1980, Dr. Osborn's An Introduction to Cerebral Angiography has been "the" definitive text on this imaging modality. Now, this classic work has been completely revised, reorganized, and updated and expanded from an introductory book into a comprehensive, state-of-the-art reference on cerebral angiography.Diagnostic Cerebral Angiography, Second Edition, is organized into three major parts. Part 1 covers techniques and technical aspects of cerebral angiography. Part 2 is a detailed description of normal anatomy, anatomic variations, and congenital anomalies. Part 3 focuses on pathological entities, including trauma, aneurysms, stroke, vascular malformations, atherosclerosis, and vasculitis.Coverage includes new information on vascular territories, film subtraction, and magnetic resonance angiography. The text is thoroughly illustrated with 1,200 radiographs and line drawings, all of them new to this volume. Another new feature of this Second Edition is the use of boxed summaries throughout the text to highlight key points.

Concise, portable, and user-friendly, The Washington Manual (R) General Internal Medicine Consult, Third Edition , provides quick access to the essential information needed when performing an inpatient consult. Chapters are organized around presenting symptom (e.g., approach to nausea, approach to low back pain), allowing quick look-up of differential diagnosis and management. Ideal for medical students, residents, and practitioners, the manual is also useful as a quick-reference guide for practicing hospitalists. Key Features: Brief, focused information throughout, zeroing in on the essential diagnosis and assessment information you need for an internal medicine consult. Thoroughly revised to include new approaches to diagnosis and new therapeutic management, as well as an all-new chapter on venous thromboembolic disease. Organized by presenting symptom, making information easy to find so you can maximize your time spent during the consult. Perfect for residents asked to perform a medical consult, hospitalists, students, NPs, and PAs. Written by residents, fellows, and attending physicians from the Washington University School of Medicine in St. Louis. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options offer the ability to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Fully revised for its third edition, the Oxford Handbook of Clinical Diagnosis provides a concise and practical summary of the reasoning processes behind clear and confident diagnosis. The handbook is set out systematically with symptoms and signs through each specialty, and includes a detailed description of the basis of logical evidence-based differential diagnosis. This new edition has been updated with more straightforward diagrams as well as brand new images to help aid understanding. Including rarer diagnoses alongside common conditions, and vital information about longer-term management alongside the initial treatments, this handbook will ensure your excellence and confidence no matter what signs and symptoms your patient presents with. Providing practical help when dealing with problems outside your area of expertise or with unforeseen situations, you can be sure that this handbook will be the reader's perfect companion to sharp and self-assured diagnoses throughout their medical career.

A tell all book about the most sought out childhood disorder. You will read about ADHD/ADD and why there has been a massive increase in a diagnosis and increase in pharmaceutical sales of ADHD. Can the Government be pushing for a diagnosis? How are the pharmaceutical companies profiting? Is there an overdosing and over diagnosing of ADHD? If it's not a lack of "attention" the child has, why is it called attention deficit hyperactivity disorder? What actually causes ADHD? It is a must read for all parents. Find out why children with high I.Q's are being labeled as ADHD.

A detailed account of one womans experience after suddenly being diagnosed with a benign meningioma brain tumor. The symptoms that lead to a diagnosis are nothing more than an irritating, involuntary twitch in the left leg which are self-diagnosed as maybe a trapped nerve in the back. No headaches, no dizziness and certainly no pain. This account reveals the emotional roller coaster that unfolds and the fear experienced by Lynda and her family and friends. Relayed in a day by day diary of events from diagnosis, through surgery to an uplifting successful outcome. The Author supplies further reading and helpful contacts and forums for others who find themselves in the same situation. A proportion of each book sold is donated to Brain Tumour Research.

Organized alphabetically by test, this reference guide provides quick and reliable access to information on over 420 laboratory tests and diagnostic procedures. With additional information provided for each procedure and extensive nursing implications with client teaching material, this book is an invaluable resource for nursing students and professionals alike.

The Oxford Handbook of Key Clinical Evidence provides an alternative to the burgeoning repositories of trial data for students, trainees, and researchers looking for the key evidence affecting medical practice. Recognizing the growing importance of evidence-based medicine (EBM) to both the study and the practice of medicine and surgery, the editors have aimed to provide a quick-reference text that presents the key data, facts, and evidence informing medical and surgical practice on a daily basis.
Introductory chapters give the "uninitiated" reader a firm footing in the history of EVM and its current importance within medical science. Readers are introduced to the current statistical methods and tools that are needed to analyze and critically assess trial data, providing a key for the terms and statistical methods encountered in the book and within medical research as a whole.
Leading figures in the specialties have selected and summarized the most important modern trials, creating a two-page format for each study which distills the key information. Highlighted boxes identify the study type and evidence-level attained, while analysis of the key message and impacts of the trial firmly place the evidence into a practical setting for the reader. Key study features and results are examined, while the difficulties or problems associated with the trials are outlined.
This is essential reading for all medics with an interest in the fundamental evidence underpinning modern practice.

Widely accepted as the most reliable medical reference on impairment evaluation since its inception in 1971, the Guides is highly valued by physicians who use its authoritative chapters to determine how to assess for impairment. The new edition of the Guides continues to build from this legacy by focusing on physician interrater reliability through an updated consensus approach that considers the latest evidence and patient function. The result is a new standard that seeks to evaluate impairment using a series of uniform grids for each chapter. Covering every body system, Guides Sixth Edition provides a standardized approach to determine impairment assessment using patient history, physical examination and clinical tests. Uniformity and ease of use is stressed to provide a consistent rating for conditions in each of the body systems using evidence based methodologies and, when lacking, a consensus approach. The Guides was developed with open deliberations from participating national medical specialty societies and state medical associations. An oversight advisory panel was established to broaden fuller participation of stakeholders. An Editorial Panel was created to review past editions and make recommendations and oversee the development of the Sixth Edition. An expansive stakeholder review was implemented to ensure consensus based content and expert medical review.

Best of Five MCQs for the MRCP Part 1 volumes 1-3 offers a comprehensive and trustworthy solution to anybody wishing to sit, pass and excel at the Membership of the Royal College of Physicians Part 1 examination. Presented as a unique three-volume set, each volume features 375 high-quality practice questions on each of the systems and specialties in alphabetical order. Volume 2 features Best of Five questions on dermatology, endocrinology, gastroenterology, geriatric medicine, infectious diseases, and ophthalmology. All 375 questions contain questions written and reviewed by successful candidates and previous examiners, and are accompanied by detailed explanations and further reading, ensuring complete and successful revision for this challenging exam. Matched to the latest Royal College curricula in coverage and format, this dedicated resource provides readers with an accurate, authoritative and evidence-based companion to the MRCP Part 1.

Biopsy Pathology of the Bronchi is intended to provide the practicing pathologist with a convenient source of diagnostic information, combined with pertinent clinical patterns and a background of histogenesis. It is hoped that the book will facilitate the accuracy of diagnosis, minimize pitfalls of interpretation and assist in the rapid evaluation of acute and chronic bronchial lesions, including neoplasms. Biopsy is taken in the widest sense and the book includes discussions on cytology, microbiopsies (fine needle aspiration biopsies, curette samples, and biopsies obtained by microforceps) and macrobiopsies, obtained at the time of surgery. Part I of the book deals with the procurement and preparation of bronchial specimens and includes a chapter on fetal development and structure of the normal adult epithelium. In Part II, the histopathology of numerous bronchial diseases are described in detail. Emphasis is placed on the diagnostic features of human lesions' which are illustrated by numerous high quality light and electron micrographs. Understanding normal bron chial structure, cell kinetics, and modulations of phenotypic expression provide insight into many pathological processes. Therefore, although emphasis is placed on the diagnostic features of human disease, the histopathology of corresponding lesions in experimental animals is dis cussed where this provides information helpful in the interpretation of the human lesions. Elizabeth M. McDowell Baltimore Theodore F. Beals Ann Arbor 1985 viii Acknowledgments We give thanks to friends and colleagues who reviewed one or more chapters for us during the writing of this book."

This book puts forward a Hypothesis on the Origins of Cancer. In this context it investigates the pre-history of a malignant illness and the maldevelopments within the human organism occurring during this period. Central to the cause for the onset of cancer is an adrenaline deficiency caused by exhaustion of the chromaffin system after long-lasting stress. It will be demonstrated that an acid / alkali imbalance and the weakening of the immune resistance have a carcinogenic effect. Findings from experience point to the disturbance of the interaction between adrenaline and insulin, the resulting glycogen overloading and oxygen deficiency of cells, setting off the cells' emergency programme, namely anaerobic, i.e. restricted cell metabolism. Furthermore, a therapy based on this hypothesis on the origins of cancer is introduced, which has as its goal the healing of the organism of a malignant illness. This book is intended for a broad public readership and contains varied historic and general references in addition to the medical core subject.

The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world, as well as being a key resource for medico-legal practitioners. Accessible digitally with regular updates, as well as in print, readers are provided with multiple avenues of access depending on their need and preference. More comprehensive, more authoritative, and more international than any other textbook; Oxford Textbook of Medicine focuses on offering both perspective and practical guidance on clinical management and prevention of disease. Introductory sections focus on the patient experience, medical ethics and clinical decision making, outlining a philosophy which has always characterized the Oxford Textbook of Medicine. It is humane, thought-provoking, and aims to instill in readers an understanding of the role of medicine in society and the contribution it can make to the health of populations, and it does not shy away from discussion of controversial aspects of modern medicine. As always, there is detailed coverage of all areas of internal medicine by the world's very best authors. The Oxford Textbook of Medicine seeks to embody advances in understanding and practice that have arisen through scientific research. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in-depth coverage of the traditional specialty areas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include stem cells and regenerative medicine; inequalities in health; medical aspects of pollution and climate change; travel and expedition medicine; bioterrorism and forensic medicine; pain; medical disorders in pregnancy; nutrition; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly. In response to ongoing user feedback there have been substantial changes to ensure that the Oxford Textbook of Medicine continues to meet the needs of its readers. Chapter essentials give accessible overviews of the content and a new design ensures that the textbook is easy to read and navigate. The evidence-base and references continue to be at the forefront of research. New to this edition is that purchasers of the print version of the Oxford Textbook of Medicine sixth edition will have free access on Oxford Medicine Online to all the content plus regular updates for the life of the edition.

Everything you need to know about the DSM-5 in an organized and concise presentation Providing you with a quick and easy way to get up-to-speed on recent changes to the two main classification systems DSM-5 Essentials highlights these changes in a logical and systematic manner so that you can easily make the transition from DSM-IV to DSM-5. Author Lourie Reichenberg offers health care providers, instructors, clinicians in practice settings, and office staff who do coding for insurance reimbursement the information they need to do their jobs smoothly and efficiently with coverage of: * The twenty classifications of disorders * Emerging measures and models * The future of diagnosis and treatment planning * Matching clients' needs with the best evidence-based treatment * Major changes to the DSM-5 such as the replacement of the multiaxial system, the developmental and lifespan approach, and cultural and gender considerations Arranged in the same sequence as the DSM-5, DSM-5 Essentials covers what has changed from the DSM-IV, what these changes mean for diagnosis, and the implication of these changes on the selection of effective, evidence-based treatment.

This scarce antiquarian book is a facsimile reprint of the original. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions that are true to the original work.

Designed for quick reference, Algorithmic Diagnosis of Symptoms and Signs: A Cost-Effective Approach equips you to effectively interpret more than 230 of the most common symptoms and signs. The ideal aid for the busy clinician, this handy, portable resource promotes a cost-effective patient workup, explaining which diagnostic tests are most appropriate (and when such tests are not indicated). Comprehensive updates throughout put the very latest diagnostic approaches at your fingertips. Features: Evaluate patients efficiently using clear, step-by-step algorithms that spell out what to look for, what tests to order, what differentials to consider, and when to refer to a specialist. Master essential clinical skills with a new section on "Getting the most out of your history and physical examination." Effectively evaluate more conditions through new algorithms for various symptoms and laboratory tests, including algorithms representing diseases that are symptoms of other diseases. Recognize diagnostic alternatives at a glance thanks to differential diagnostic tables. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Acutely unwell patients can deteriorate dangerously without timely recognition and intervention. Emergencies in Clinical Medicine provides an easy-to-use guide to the prompt management of common medical emergencies. Designed for rapid use, it explains how to arrive at a differential diagnosis and how to prevent, manage, or treat an emergency. The second edition has been fully updated to reflect current clinical guidelines and includes several new topics, from pulmonary oedemas to the overdose patient. Revised to cover the curricula for core medical training (CMT) and acute care common stem (ACS), this text addresses exactly what the trainee doctor needs to know. The text covers emergencies from both a problem-based and disease-based approach. Cross-referencing between these two sections enables quick reference under pressure, with clear, step-by-step instructions and advice on when and who to call for help. With key algorithms for quick reference and easy to follow symbols indicating clinical severity, from life-threatening to minor, this text will help clinical staff managing acutely ill patients in an easy-to-read and portable format.

Medical tests consume considerable resources and yet making requests is often left to the most junior members of the team. Medical schools often under prepare junior doctors for these tasks so they tend to request large numbers of tests to make sure 'all bases are covered' by the time a more senior colleague attends to the patient. Beginning with naive questions such as 'what is a medical test?' and 'why do we perform tests?', the book also covers the evaluation of tests from a public health perspective and helps the readers to determine whether a test should be introduced into clinical care. By describing the basics of medical decision making based on probability thresholds, students will learn how to avoid unnecessary testing when results are unlikely to influence patient relevant decisions, and the pros and cons of using metrics such as sensitivity, specificity, and predictive values. Illustrated throughout with real life examples from multiple medical and surgical specialties, it concludes with a novel checklist for doctors to consider every time they think of requesting a test. Written by a clinician for clinicians, this book is ideal for medical students and junior doctors. It provides everything they need to know to become experts at requesting tests. It will support them in requesting the most appropriate and effective tests, and inform them on how to interpret results, improving patients' outcomes.

The Medical Interview by Drs. Steven A. Cole and Julian Bird equips you to communicate effectively with your patients so you can provide optimal care! This best-selling, widely adopted resource presents a practical, systematic approach to honing your basic interviewing skills and managing common challenging communicating situations. Its Three-Function Approach - "Build the Relationship," "Assess and Understand," and Collaborative Management" offers straightforward tasks, behaviors, and skills that can be easily mastered, making this an ideal learning tool for beginners and a valuable reference for experienced healthcare professionals. Effectively meet a full range of communication challenges including language and cultural barriers, sexual issues, elderly patients, breaking bad news, and non-adherence. Easily apply proven techniques with help from supportive case examples and actual interview questions. Get the skills you need now with new chapters covering advanced topics and applications including "Presentation and Documentation," nonverbal communication, using psychological principles in medical practice, and integrating structure and function. Quickly review information with summary tables, boxes and bulleted lists. Get access on the go with the fully searchable text online at Student Consult, including cost-free access to a specially customized, interactive web-based Module on Brief Action Planning (BAP), a key component of the web-based, interactive Comprehensive Motivational Interventions (CMI)T e-learning platform.

Back by popular demand: the world's most widely-used medical reference, now in its 20th edition. The Merck Manual of Diagnosis and Therapy has been thoroughly updated and expanded with a larger trim size to include 40% new and revised content, including 36 new chapters with more than 200 tables and 100 figures. Packed with essential information on diagnosing and treating medical disorders, this comprehensive guide was written by a team of renowned medical experts. It is intended for everyday use by healthcare professionals to ensure delivery of the best care to their patients. The new Merck Manual of Diagnosis and Therapy makes it easy to find the right information at the moment it's needed, with the help of section thumb tabs. It is a must-have for medical students, residents, practicing physicians, nurses, and allied health professionals. New larger trim 7 3/4 x 9 1/4 to accommodate 40% new content 36 completely new chapters Revised and expanded chapters in Cardiovascular, Genitourinary, Gynecologic, Neurologic, Pregnancy, and Infants and Children Pediatrics and trauma section significantly revised and expanded Key Points summarize the facts at-a-glance New Pearls & Pitfalls highlight noteworthy medical info and areas of caution 16-page full-color insert aids visual recognition of skin, eye, and oral disorders

Blood transfusion is considered a life-saving therapy since ancient times, but, at the same time, a high-risk procedure. Nowadays the common perception is that infection is the greatest risk, even if the blood has never been safer from this point of view. Currently, the residual risk of transfusion must be related mainly to immunological mechanisms underlying to AB0 and minor blood systems, to compatibility of blood transfused and to development of irregular antibodies in transfused patients. "Transfusion Medicine and Patient Safety" aims to provide the basic of immunohematology to readers and to analyze the transfusional process highlighting the most critical points, thus more exposed to errors. Screening on blood and blood components for infectious diseases along with the surveillance action on emerging viruses results in the drastic reduction of post-transfusion infection, together with the potential to further increase the level of security from infection through the inactivation of blood components. The text also describes the major diagnostic systems and organizational models that modern technology provides us with a correct immunohematological diagnosis and an appropriate trasfusional therapy.

This text provides students and practitioners with the essential diagnostic information for clinical problems as well as a system for differentiation of diseases that have similar signs, symptoms, and radiographic appearance. Pathogenesis, clinical, radiographic, laboratory, and histopathological features are presented with discussion developed especially to highlight distinguishing features and helpful hints in generating a differential diagnosis for each lesion.

Improve your skills in visual diagnosis Speed and accuracy of diagnosis is the key to saving lives in emergency and critical care medicine. Careful visual inspection of the patient, the data (radiography, electrocardiogram), and related clues can often help providers choose the right diagnosis and ultimately the best treatment -- but this knowledge comes with experience. This book provides 110 randomly presented visual diagnosis cases for self-testing, imitating real-life situations found in the emergency department setting. Written by distinguished emergency and critical care physicians, and thoroughly revised and updated throughout, this second edition includes 25% new cases and is an ideal aid for trainees preparing for Board examinations as well as an invaluable refresher' for qualified emergency and critical care providers.

The first resource of its kind, Palliative and Serious Illness Patient Management for Physician Assistants provides a fundamental framework for physician assistants and physician associates to incorporate palliative care medicine, including end-of-life care, into their practice. The book focuses on pharmacologic and integrative medical therapeutic modalities, as well as the evaluation and treatment of special populations, which reflects the reality of a physician assistant's day-to-day job. It uses a patient-centered approach to address the comprehensive management of serious illness patients, as well as their designated families, significant others, caregivers, and health care providers. Chapters are organized into six sections that cover the essential aspects of care, symptom management, and transitioning care at the end-of-life. This book is ideal for physician assistant trainers (didactic or clinical), students, and practicing clinicians who seek to enhance their communication and medical skills in the treatment of all seriously illness patient populations in any specialty, and in the management of their symptoms at any stage of their disease or condition.