Nanobiosensors have been successful for in vitro as well as in vivo detection of several biomolecules and it is expected that this technology will revolutionize point-of-care and personalized diagnostics, and will be extremely applicable for early disease detection and therapeutic applications. This book describes the emerging nanobiosensor technologies which are geared towards onsite clinical applications and those which can be used as a personalised diagnostic device. Biosensor technologies and materials covered include electrochemical biosensors; implantable microbiosensors; microfluidic technology; surface plasmon resonance-based technologies; optical and fibre-optic sensors; lateral flow biosensors; lab on a chip; nanomaterials based (graphene, nanoparticles, nanocomposites, and other carbon nanomaterial) sensors; metallic nanobiosensors; wearable and doppler-based non-contact vital signs biosensors; and technologies for smartphone based disease diagnosis. Clinical applications of these technologies covered in this book include detection of various protein biomarkers, small molecules, cancer and bacterial cells; detection of foodborne pathogens; generation and optimisation of antibodies for biosensor applications; microRNAs and their applications in diagnosis for osteoarthritis; detection of circulating tumor cells; online heartbeat monitoring; analysis of drugs in body fluids; sensing of nucleic acids; and monitoring oxidative stress.

The author presents a new approach to the therapy of stuttering. Instead of accepting stuttering and trying to make it more fluent, he prefers to motivate a patient to effectively battle the condition. This book presents a theoretical basis for such an approach and offers diagnostic tools, including normalised and standardised scales as well as questionnaires for examining patients with stuttering in different age groups. While guest authors review research on the effects of pharmacotherapy, which is regarded as controversial by many, the author focuses on discussing the approach and achievements of Central and Eastern European therapists which have not been heard of in the USA and Western European countries. He supports systemic therapy which affects all the basic stuttering factors (ie: speech disfluency, logophobia, muscle tension and interpersonal communication in a comprehensive way). Speech disfluency is not regarded as a problem, but merely as an obstacle on the way to accomplish a patients personal goals. The author presents particular methods for solving the problems of patients with stuttering and considers motivation to therapy important, though it is reduced due to the acceptance of the disorder. Although he supports using natural speech in the course of therapy, he does not reject other techniques. On the contrary, the author believes that therapeutic methods should be adjusted to the needs and abilities of a patient instead of forcing said patient to use a method simply because it is universal. The author believes therapies are subjective to the patient in question. Additionally, the author is optimistic and encourages both therapists and patients to share his optimism as well.

This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Magnetic Resonance Imaging is a very important clinical imaging tool. It combines different fields of physics and engineering in a uniquely complex way. MRI is also surprisingly versatile, 'pulse sequences' can be designed to yield many different types of contrast. This versatility is unique to MRI. This short book gives both an in depth account of the methods used for the operation and construction of modern MRI systems and also the principles of sequence design and many examples of applications. An important additional feature of this book is the detailed discussion of the mathematical principles used in building optimal MRI systems and for sequence design. The mathematical discussion is very suitable for undergraduates attending medical physics courses. It is also more complete than usually found in alternative books for physical scientists or more clinically orientated works.

The story about Dionn Fields Inc. Its my goal to help woman fight Uterine Cancer. To honor my mother's memory (Theresita Fields) 10-16-48 - 10-26-12. And to raise funds for a new facilty in Atlanta near the Cancer Center of America.

In the 19th century, a greater understanding of childrens rights was acknowledged, and in the 20th century, child abuse was discovered in 1962 after many years of turning a blind eye. The number of reported cases of child abuse worldwide has since exploded into a public health epidemic with a much higher incidence than better-funded diseases such as juvenile cancer. The evaluation of child abuse and neglect is complex, with many professionals and agencies involved to try and decrease these incidences. This can be one of the reasons why the field has not been able to attract appropriate resources for prevention, treatment, education and research. Child abuse must be looked upon as a major public health problem, and professionals must make the 21st century a century for the child. In this book, the authors have given a short review of the field.

The practice of dermatopathology has evolved from viewing predominantly haematoxylin and eosin (H&E)-stained sections through the microscope to include an array of more specialized tests. These are used as stand-alone tests or in addition to the H&E. Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is a practical guide to the most important of these new diagnostic techniques. Aside from a brief review of H&E in the Introduction, the focus of the book is on the wide range of more recent ancillary tests commonly used by clinicians, including sections on special stains, immunohistochemistry, immunofluorescence, electron microscopy and molecular testing. Each section describes why each of these tests is performed, how to use them and how to interpret the results they provide. Abundantly illustrated with colour photographs, diagrams and algorithms Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is packed with practical guidance on commonly-faced diagnostic dilemmas, how the tests described can be used to resolve them and how to avoid pitfalls in the diagnostic process. The book is an essential resource for trainee and practicing dermatopathologists, dermatologists and pathologists seeking an accessible guide to the diagnostic methods which are increasingly important in dermatopathology and which go beyond the H&E.   Key features Covers the full range of diagnostic tests in dermatopathology, aside from H&E, with a focus on practical clinical information such as how to run the test, when to use it and how to interpret the results Includes special stains, immunohistochemistry, immunofluorescence, electron microscopy, molecular testing and point of care tests including potassium hydroxide preparations, mineral oil preparations, and Tzanck smears Single author with hand-picked specialist contributors provide a consistent approach to the subject, replete with diagnostic tips and clinical advice based on extensive personal experience

Since the publication of the first edition of the Handbook in 2002, optical methods for biomedical diagnostics have developed in many well-established directions, and new trends have also appeared. To encompass all current methods, the text has been updated and expanded into two volumes. Volume 1: Light - Tissue Interaction features eleven chapters, five of which focus on the fundamental physics of light propagation in turbid media such as biological tissues. The six following chapters introduce near-infrared techniques for the optical study of tissues and provide a snapshot of current applications and developments in this dynamic and exciting field. Topics include the scattering of light in disperse systems, the optics of blood, tissue phantoms, a comparison between time-resolved and continuous-wave methods, and optoacoustics. Volume 2: Methods begins by describing the basic principles and diagnostic applications of optical techniques based on detecting and processing the scattering, fluorescence, FT IR, and Raman spectroscopic signals from various tissues, with an emphasis on blood, epithelial tissues, and human skin. The second half of the volume discusses specific imaging technologies, such as Doppler, laser speckle, optical coherence tomography (OCT), and fluorescence and photoacoustic imaging.

Western medicine treats sick patients like broken machines -- figure out what is physically wrong, fix it, and send the patient on their way. But humans are not machines. When we are ill, we experience our illness: we become scared, distressed, tired, weary. Our illnesses are not just biological conditions, but human ones. It was Arthur Kleinman, a Harvard psychiatrist and anthropologist, who saw this truth when most of his fellow doctors did not. Based on decades of clinical experience studying and treating chronic illness, The Illness Narratives makes a case for interpreting the illness experience of patients as a core feature of doctoring. Before Being Mortal or The Body Keeps the Score, there was The Illness Narratives. It remains today a prescient and passionate case for bridging the gap between patient and practitioner.

'Medical technology is beneficial for well researched dangerous diseases. However, most symptoms that people bring to their primary care physician have no single clearly identifiable cause: investigations and drugs do more harm than good - and also waste resources - ' - Wilfrid Treasure Diagnosis and Risk Management in Primary Care teaches that adopting an evidence-based approach to primary care improves patient care and treatment outcomes. It demonstrates that brief clinical assessments, repeated if necessary, allow effective diagnosis while avoiding the costs and complications associated with more advanced testing. Adopting a fresh approach, this book sets consultation skills alongside evidence-based information by both itemising the specific techniques and facts that are needed in the consulting room, and providing detailed information on odds and likelihood ratios to quantify risk and deal with uncertainty. This book provides food for thought, and helps doctors develop communication skills that support their personal styles of consulting, encouraging a more traditional, intuitive treatment. It provides a map of the consultation and a compass to navigate through symptoms, signs and evidence - listening to their patients with one ear and, with the other, to the reflective inner voice of reason. General Practitioner Specialist Trainees and their teachers will find much of interest, as will established General Practitioners with an interest in maintaining traditional models of care. Undergraduate medical students and candidates for the MRCGP will find this an ideal reader for the clinical skills assessment. 'What a breath of fresh air to find an author capable of putting the patient back at the centre of the consultation and who is able to entertain at the same time as he informs and to stimulate critical reflection while nudging us in the direction of a rigorous approach to diagnosis, and the assessment and communication of risk.' From the foreword by Roger Jones

Sinusitis, Hay Fever, and Allergic Rhinitis is widespread and affects millions of people. This books aims to provide the information sought out by those millions of people. Frederick Earlstein has written this medical education guide to provide an understanding of Sinusitis, Hay Fever, and Allergic Rhinitis with the goal of providing relief. Symptoms, signs, treatment, remedies, relief, cure, natural remedies, prevention, home remedies, medicine, vaccine, and surgery all covered The book is written in an easy to read and understandable style. In a straight forward, no nonsense fashion, Frederick Earlstein covers all aspects of Sinusitis, Hay Fever, and Allergic Rhinitis. The book is full of informative content and answers to your questions - including some you didn't know you had