Immunoassays are among the most powerful and sensitive technologies now available for patient diagnosis and monitoring. This book is an indispensable guide to information on the theory and practice of immunoassays. It discusses the scientific basis of these technologies in a logical, organized, and heuristic manner and provides protocols for specific assays. The contents of this unique book are balanced among theory, practical issues, quality control, automation, and subspecialty areas, making it ideal for health science students, laboratory scientists, and clinicians.
Key Features
* Presents up-to-date information
* Provides extensive cross-referencing
* Covers theory and practice in full detail
* Written by leading authorities

Differential Diagnosis of Neuromusculoskeletal Disorders is a pocket-sized handbook designed to provide the chiropractic physician, intern, and student with a quick reference manual for differential diagnosis. The topics covered encompass most of the syndromes seen in everyday chiropractic cases involving neurology, orthopaedics, and diagnostic imaging.

A didactic, illustrated guide to the use of ultrasound as a diagnostic tool in clinical practice. Prepared by an international group of experts with wide experience in both developed and developing countries, the manual responds to the need for a basic reference text that can help doctors, sonographers, nurses, and midwives solve imaging problems when no experts are available. With this need in mind, the manual adopts a practical approach aimed at providing a thorough grounding in both the techniques of ultrasound and the interpretation of images. The need for extensive supervised training is repeatedly emphasized. Because the clinical value of ultrasound depends so greatly on the experience and skill of the operator, the manual makes a special effort to alert readers to common pitfalls and errors, and to indicate specific clinical situations where ultrasound may not be helpful or reliable as a diagnostic tool. Explanatory text is supported by numerous practical tips, warnings, checklists and over 600 illustrations. The opening chapters explain how ultrasound works, outline the factors to consider when choosing a scanner, and introduce the basic rules of scanning, including advice on how to recognize and interpret artefacts. Guidance on the selection of ultrasound equipment includes clear advice concerning where costs can be spared and where investment is essential. The core of the manual consists of seventeen chapters providing guidance on scanning techniques and the interpretation of images for specific organs and anatomical sites, with the most extensive chapter devoted to obstetrics. Each chapter contains illustrated information on indications for scanning, preparation of the patient, including choice of transducer and setting of the correct gain, general scanning techniques, and specific techniques for identifying anatomical landmarks and recognizing abnormalities. The manual concludes with WHO specifications for a general-purpose scanner judged entirely suitable for 90-95% of the most common ultrasound examinations.

The transformation from medical student to physician is a gradual one, requiring the assimilation of vast amounts of knowledge as well as the development of the ability to "think like a doctor." The thought processes that enable a physician to "think like a doctor" are perhaps the most difficult skills the clinician-in-training must acquire in medical school and residency. In this extraordinary book, Dr. Howard Barrows, one of the world's foremost medical educators, beautifully and simply articulates those mental processes that allow accomplished physicians to reach diagnostic conclusions with speed and confidence. Students who master the contents of this book will take a long step forward in acquiring the diagnostic skills that are the hallmark of the experienced physician.

Oxford Handbooks Clinical Tutor Study Cards are a new, innovative, and versatile aid to revision from the publishers of the famous Oxford Handbooks. Following the same portable format, each card covers a discrete topic, enabling students to revise in bite-sized chunks quickly and safely whilst on the move. These handy double-sided cards can also be used when carrying out an examination, containing the vital techniques and tips students need to know. They are split up into defined sections to allow the reader to find topics quickly, and are supplemented with full colour illustrations to aid quick and confident diagnoses.
This set of surgery cards takes a system and anatomical-based approach, covering all essential conditions and diseases in just 132 cards. Each card first looks at clinical examination, before covering the need-to-know essentials: background and epidemiology, presentation, differential diagnosis, and suitable investigations, followed by treatment or management.

Diagnostic Lymph Node Pathology presents a logical and systematic approach to lymph node biopsies and guides general pathologists and haematopathologists alike through the maze of differential diagnoses, enabling them to reach an accurate diagnosis. The book is presented in an easy-to-read format and contains boxes for quick reference detailing the clinical, morphological, immunohistochemical, and genetic features of each entity. Thoroughly revised, the third edition also includes more than 300 high-quality histological colour photographs along with updated references. This edition covers both classical and less well-known features of individual disease processes. It is a valuable guide for both professionals and trainees.

Mit der Geschichte der Histopathologie wird ein beeindruckendes Stuck Medizingeschichte jetzt erstmals umfassend dokumentiert. Folgen Sie dem Autor auf einer faszinierenden Reise von den Anfangen bis zur Gegenwart: o in die Pariser Schule des 19. Jahrhunderts und zu den verschiedenen Forschungsstatten in Frankreich, im deutschsprachigen Raum, in Grossbritannien und den USA, o auf den Spuren der Persoenlichkeiten, die die Entwicklung der Histopathologie pragten, o zu den Meilensteinen des Fortschritts, der die Histopathologie in den letzten Jahrzehnten revolutioniert hat. Eine Reise, nach der Sie Ihre tagliche histopathologische Diagnostik mit anderen Augen sehen! -> Im Mittelpunkt steht die Einfuhrung des Mikroskops in der Krankheitsforschung und Diagnostik. Im Fokus: Die chirurgische, gynakologische und dermatologische Pathologie des 19. und 20. Jahrhunderts. -> Mit einer Sammlung eindrucksvoller Holzschnitte, Kupferstiche und Lithographien

Il libro prende le mosse dai pensieri di un giovane che alla maturita liceale si trova affascinato dalla cultura dei classici greco-latini, dai rudimenti filosofici e dall impatto con le scienze fisiche e naturali. Il latino e i suoi naturalisti hanno suscitato un fervore verso la Botanica Sistematica che lo riporta a Linneo e quindi alla conoscenza del mondo naturale, all esperienza della denominazione dell esistente come conoscenza e quindi agli universali di Guglielmo d Occam. La scelta della facolta di Medicina fungera da mediazione fra la filosofia, vista come via alla verita, e la biologia con il grande mistero dell uomo nella sua dualita di mente/corpo. L incontro con il microscopio aprira la strada all approfondimento della biologia, ma anche alla ricerca dei significati e delle interpretazioni del mondo. I meccanismi della percezione, visiva in particolare, nelle articolazioni della Gestaltpsychologie, e i suoi rapporti con il mondo interiore, sia quello della memoria esplicita che della memoria implicita, sono affrontati nell esplorazione del mondo attraverso il microscopico e nella ricerca di una obiettivita scientifica. Locke e Kant, Popper e Heidegger fanno da contraltare a Ramon y Cajal, Golgi, Kandel, Heisenberg, mentre la semiotica illumina e confonde sull importanza del linguaggio per la conoscenza. Il segno e il suo riconoscimento si trasferiscono nella scienza attraverso l inter-soggettivita e il linguaggio appare come l unico modo di penetrare l esistente. Il libro si dilunga sull origine di certe denominazioni in patologia tratte dalla vita quotidiana, sull antropomorfismo spesso applicato agli oggetti del campo microscopico, sempre illustrati su base fenomenologica e psicologica.

A Davis’s Notes book! This pocket-sized reference provides great information on phlebotomy techniques, with nice summaries of procedures with many photos and illustrations. It is ideal for clinical rotations, for quick review of coursework, and to study in preparation for your certification exam. The write-on/wipe-off pages feature a dedicated space where you can fill in the specific requirements for evacuated tubes, instrumentation, and analytical procedures for two different locations. Clinically focused, it’s the perfect guide to collecting, transporting, and processing quality blood specimens for laboratory testing. Essential Pocket Guide for Phlebotomy! "It has a lot of information, with step-by-step instructions with pictures. This is essential if you will be doing any phlebotomy of any kind." - Pamela O., Amazon Reviewer Great resource. "Love this book! While doing my externship this book was recommended to me. I am very glad that I ordered it. It includes labs and the corresponding tube colors which is something I needed. It is wipeable and will fit in the pocket of my scrubs. I have already recommended it to the other students who were in class with me." - T.S, Amazon Reviewer Phlebotomist Must Have! "These Phlebotomy Notes were very helpful overviewing all key notes for my Exam and while doing my Clinicals, very easy to navigate. Will continue to use it through my Career in Phlebotomy." - Cali, Amazon Reviewer

The practice of dermatopathology has evolved from viewing predominantly haematoxylin and eosin (H&E)-stained sections through the microscope to include an array of more specialized tests. These are used as stand-alone tests or in addition to the H&E. Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is a practical guide to the most important of these new diagnostic techniques. Aside from a brief review of H&E in the Introduction, the focus of the book is on the wide range of more recent ancillary tests commonly used by clinicians, including sections on special stains, immunohistochemistry, immunofluorescence, electron microscopy and molecular testing. Each section describes why each of these tests is performed, how to use them and how to interpret the results they provide. Abundantly illustrated with colour photographs, diagrams and algorithms Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is packed with practical guidance on commonly-faced diagnostic dilemmas, how the tests described can be used to resolve them and how to avoid pitfalls in the diagnostic process. The book is an essential resource for trainee and practicing dermatopathologists, dermatologists and pathologists seeking an accessible guide to the diagnostic methods which are increasingly important in dermatopathology and which go beyond the H&E.   Key features Covers the full range of diagnostic tests in dermatopathology, aside from H&E, with a focus on practical clinical information such as how to run the test, when to use it and how to interpret the results Includes special stains, immunohistochemistry, immunofluorescence, electron microscopy, molecular testing and point of care tests including potassium hydroxide preparations, mineral oil preparations, and Tzanck smears Single author with hand-picked specialist contributors provide a consistent approach to the subject, replete with diagnostic tips and clinical advice based on extensive personal experience

In the 19th century, a greater understanding of childrens rights was acknowledged, and in the 20th century, child abuse was discovered in 1962 after many years of turning a blind eye. The number of reported cases of child abuse worldwide has since exploded into a public health epidemic with a much higher incidence than better-funded diseases such as juvenile cancer. The evaluation of child abuse and neglect is complex, with many professionals and agencies involved to try and decrease these incidences. This can be one of the reasons why the field has not been able to attract appropriate resources for prevention, treatment, education and research. Child abuse must be looked upon as a major public health problem, and professionals must make the 21st century a century for the child. In this book, the authors have given a short review of the field.

Coagulopathy (also called clotting disorder and bleeding disorder) is a condition in which the blood's ability to clot (coagulate) is impaired. Acquired hemophilia is a rare disorder characterized by spontaneous bleeding in a patient with no previous personal or family hemorrhagic history. The first chapter explores the challenges associated with this disease, its unfamiliarity often causing a delay in diagnosis and therapeutic approaches. The second chapter focuses on lower gastrointestinal bleeding (LGIB) in children, describing the epidemiology, etiology and clinical management. The third chapter reviews the pathogenesis, risk factors and treatment strategies of coagulopathy in patients with craniocerebral injury. The next article examines Vitamin B12 with its four cobalamin vitamers, which often play a role in coagulation. The next chapter starts with a description of the methodology of viscoelastic hemostatic assay, followed by a review of literature on the utilization of thrombelastography (TEG) or rotational thromboelastometry (ROTEM). Finally, the role of TEG and ROTEM to monitor or guide prophylaxis/treatment of thromboembolic events and the limitations of using them to detect hypercoagulability and identify patients with increased risks for thromboembolic complications are discussed. The final chapter of this book focuses on the use of fresh frozen plasma (FFP) in patients who are not actively bleeding, critically questions these assumptions in the context of pre-procedural administration of FFP, and also examines why carrying out high quality trails in this area has been so problematic.

Delirium is an acute change in mental status, which has the features of a fluctuating mental status, inattention, and either disorganised thinking or altered level of consciousness. It is a common development particularly in hospitalised elderly patients. Delirium is independently associated with adverse sequelae including increased mortality, institutionalisation and cognitive decline. Despite this, case identification remains poor, with up to two-thirds being missed or mis-attributed to dementia, depression and other neuropsychiatric diagnoses. This book discusses how delirium affects the critically ill; early detection of delirium; delirium in surgical patients; and delirium's connection to eating disorders.

Irritable bowel syndrome (IBS) is common and affects 5 to 20% of individuals world-wide. Physicians with various specialties and at different settings are bound to meet these patients. This book is written by clinicians with long experience with IBS patients at different settings that have performed active research on IBS from different angles. Topics discussed include the prevalence and incidence of IBS world-wide, symptoms and consequences for patients and the society; IBS symptom based diagnosis; pathogenesis and the different possible etiological factors; a new hypothesis for the pathogenesis of IBS; post-infectious and inflammatory bowel disease (IBD) associated IBS and treatment options, both non-pharmacological and pharmacological. This book does not only contain up to date data, but also included are the authors' points of view and their argument in several debated issues in IBS.

Predictive, preventive and personalised medicine offers great promise for the future practice of medicine. Essential components of this approach include well-organised population screening protocols utilising novel diagnostic biomarkers of disease states, targeted prevention of common human pathologies, optimal treatment planning and personalised medicine thereby resulting in substantial improvement of the quality of life. This approach also offers the advantage of delivering care at potentially reduced costs to the population at large thereby addressing social and ethical issues related to access to and affordability of health care. Consequently, conventional medicine and new branches of biomedicine are currently challenging many issue-related questions: Should molecular diagnostic approaches be considered complementary or substitutive measures to conventional approaches? How reliable are biomarkers for any given pathology? How to distinguish between the highly predictive power of innovation and quackery in diagnostics? How to overcome currently well-recognisable (inter)national barriers in knowledge transfer? How to correctly educate the new generation of experts in bio- and predictive medicine? The book addresses these highly relevant issues and provides some clues for plausible solutions. The information presented in this book emphasises the necessity of individualised patient treatment and provides compelling reasons as to why "across-the-board" treatment is not warranted. Application of nutritional proteomics results in individualised optimal diet and may potentially restrict the epidemic scale of type 2 Diabetes mellitus. A broad distribution and a routine clinical utilisation of these advanced technological approaches could enable a significant portion of the population to reach the 100-year age limit yet remaining vibrant in excellent physical and mental health and as actively contributing members of society. The examples given in the book are based on well-recognised expertise, scientific publications and international patents. A panel of leading world experts and authorities of the international issue-related associations have contributed to the book by addressing relevant issues and topics such as model-based patient-care and individualised therapy-planning, reproductive medicine and postnatal diagnostics, early/predictive diagnosis and optimised treatment of cancer as well as the most frequent neurodegenerative disorders.

The Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV) guides the clinician step-by-step through the DSM-5 diagnostic process. Interview questions are provided conveniently along each corresponding DSM-5 criterion, which aids in rating each as either present or absent. A unique and valuable tool, the SCID-5-CV covers the DSM-5 diagnoses most commonly seen in clinical settings. The User's Guide for the SCID-5-CV provides comprehensive instructions on how to use the SCID-5-CV effectively and accurately. It not only describes the rationale, structure, conventions, and usage of the SCID-5-CV, but also discusses in detail how to interpret and apply the specific DSM-5 criteria for each of the disorders included in the SCID-5-CV. A number of sample role-play and homework cases are also included to help clinicians learn how to use the SCID-5-CV. Together with the SCID-5-CV, the User's Guide for the SCID-5-CV will prove invaluable to clinicians, researchers, interviewers, and students in the mental health professions who seek to integrate time-tested interview questions corresponding to the DSM-5 criteria into their DSM-5 diagnostic assessment process.

Spriggs's Essentials of Polysomnography, Third Edition is a comprehensive, full-color text designed specifically for sleep technicians and professionals. The Third Edition has earned its place as the touchstone for hospitals, sleep labs, physicians' offices,

Thousands of high-quality clinical photographs paired with authoritative clinical content make Zitelli and Davis' Atlas of Pediatric Physical Diagnosis the trusted, go-to resource for residents and physicians alike. In this thoroughly revised 8th Edition, Drs. Basil J. Zitelli, Sara C. McIntire, Andrew J. Nowalk, and Jessica Garrison, provide a much-needed visual perspective on pediatric illness, helping you hone your visual examination skills and improve your diagnostic accuracy. Features more than 3,000 color photographs supplemented by clear explanatory text, laboratory tests, tables, algorithms, imaging, and approximately 25 clinical videos. Emphasizes pertinent historical factors, examination techniques, visual findings, and diagnostic methods. Provides meticulously updated content throughout, including an extensively revised ophthalmology chapter. Discusses key topics in pediatrics such as development, child abuse, and adolescent gynecology. Covers both common and uncommon disorders, making it an excellent resource not only for clinical diagnosis, but also for studying for the pediatric boards. Lists actionable and practical references, bibliographies, and resources at the end of each chapter. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Medical Response to Adult Sexual Assault, Second Edition provides evidence-based research on diagnosis, treatment, and examination in cases of sexual violence and assault. Survivors of sexual assault face any number of unique challenges both on the path to physical and psychological recovery and in navigating the investigative and judicial processes related to their traumatic experiences. Medical practitioners who work with these survivors require informed expertise in order to support their patients' safety and personal well-being. The authors and contributors, a team of expert physicians, nurses, attorneys, and other multidisciplinary practitioners, have fully revised and updated Medical Response to Child Sexual Abuse to reflect contemporary best practices in the investigation and treatment of sexual violence. Any professionals who work with victims of sexual assault will find this latest edition essential to their responsibilities and to the renewed well-being of those in their care.

Now in a greatly expanded and updated new edition: The essential pocketbook for rapid and correct differentiation and interpretation of signs and symptoms of neurological and neurosurgical diseases and conditions. Key Features: Exhaustive range of neurologic and neurosurgical disease and conditions covered Vital information presented in short texts, high-yield lists, and concise tables, for maximum efficiency in diagnostic work-ups Clinical and neuroimaging findings, guidelines and classifications, summarized in readily accessible tabular form Statistic overviews (common vs. rare, etc.) help guide diagnostic thought processes Special chapters highlight epidemiology, pediatric disorders, neuroradiology Differential Diagnosis in Neurology and Neurosurgery is ideal as a quick reference in your daily practice, or as an exam preparation guide. This wealth of easily accessed information makes it invaluable to experienced practitioners (especially ER physicians) and to novices alike. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Conceived as a guide for practitioners in their work in dermatology, this book is unique in its approach. From cutaneous signs to the richness of differential diagnosis, it guides practitioners through every step, from semiological analysis to diagnosis. The aim is to provide readers with the essentials of relevant dermatological reasoning. The first part of the book focuses on physical examination and on recognizing basic lesions, the practitioner's building blocks. The diseases requiring understanding are then described in the form of a richly illustrated atlas, in which each diagram has been chosen as an exemplary educational tool. In the final part, differential diagnosis is proposed in the form of various tables summarizing the different cutaneous signs, providing readers with a complete toolkit to assist with diagnosis. This book will give trainee dermatologists, general physicians and internists the knowledge they need to identify basic lesions and a complete and detailed overview of the various diseases they are likely to encounter. At the same time, experienced dermatologists will find this book a valuable reference work for differential diagnosis.

2017 Choice Outstanding Academic Title With over forty years of experience as a sought after diagnostician, Dr. Stuart Mushlin has cracked his share of medical mysteries, ones in which there are bigger gambles than playing the ponies at the track. Some of his patients show up with puzzling symptoms, calling for savvy medical detective work. Others seem to present cut-and-dry cases, but they turn out to be suffering from rare or serious conditions.   In Playing the Ponies and Other Medical Mysteries Solved, Dr. Mushlin shares some of the most intriguing cases he has encountered, revealing the twists and turns of each patient’s diagnosis and treatment process. Along the way, he imparts the secrets to his success as a medical detective—not specialized high-tech equipment, but time-honored techniques like closely observing, touching, and listening to patients. He also candidly describes cases where he got things wrong, providing readers with honest insights into both the joys and dilemmas of his job.      Dr. Mushlin does not just treat diseases; he treats people. And this is not just a book about the ailments he diagnosed; it is also about the scared, uncertain, ailing individuals he helped in the process. Filled with real-life medical stories you’ll have to read to believe, Playing the Ponies is both a suspenseful page-turner and a heartfelt reflection on a life spent caring for patients.