A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

This book reviews the pathophysiology and physical manifestations of acromegaly and discusses the multiple treatment options now available for the management of the patient with acromegaly. The book contains an ample number of illustrations that help to emphasize points of particular interest, including radiological, histopathological, and physical diagnosis images. Sections are devoted to detailing important topics including determinants of pathological effects of disease activity in acromegaly, individual therapeutic choices and criteria for diagnosis, and disease control.

Intragastric balloons are steadily gaining popularity among the medical treatments available for obesity. Their efficacy and safety are reinforced by growing body of evidence obtained around the globe. Intragastric balloons are now considered one of the safest and most effective medical procedures for weight reduction. Additionally, the reduced potential for side effects and low invasiveness (compared to bariatric surgeries) are important considerations. This book is edited by renowned surgeons and endoscopists from Brazil, a country known for its reputation on the field of bariatric endoscopy and surgery. Such reputation is especially valid where the use of intragastric balloons is concerned. These devices, approved by the FDA only in 2015, have been used in Brazil since the 1990s, attesting to Brazilian expertise in the field. This book describes the various types of intragastric balloons used for the treatment of obesity, an alternative to bariatric surgery and other more invasive methods. It addresses their indications, procedures and outcomes, providing readers an overview of the therapeutic options available worldwide. It is divided into seven main sections: I - Introductory Issues; II - Devices; III - Technical Procedures and Related Issues; IV - Acute Complications and Treatment; V - Chronic Complications and Treatment; VI - Special Populations; and VII - Miscellaneous. This structure helps to promote a better knowledge construction and a reasonable flow of ideas throughout the book, guiding the reader from introductory topics to surgical procedures and complications. The book ultimately intends to offer an essential reference guide for all physicians and surgeons interested in the treatment of obese patients. It is intended for both experienced professionals looking for in-depth information and for trainees and residents seeking to broaden their perspectives concerning the treatment of obesity.

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasingimportance. Clinicians will find that the book s straightforward approach ensures that it can be easily and rapidly consulted."

Analyzes various reproductive and gynecological disorders encountered in the care of women who do not wish to conceive, as well as those who have difficulty with conception, early pregnancy, and menopause. Discusses the latest strategies in the treatment of infertility, pelvic pain, ectopic pregnancy, and osteoporosis.

Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.

The clinical benefits of hormone replacement therapy in women have to be carefully balanced against the possible risks, and a particular theoretical concern relates to risks associated with various forms of female oncology. Because of conflicting reports, gynecologists and oncologists especially need a single, authoritative resource of up-to-date information. Hormone Replacement Therapy and Cancer, published in association with the International Menopause Society, provides the very consensus statement that clinicians need in this difficult and complex area.

Many of the world's leading specialists have contributed important chapters that provide state-of-the-art knowledge about the effects of hormones on women and possible cancer risks. The introductory section deals with carcinogenesis, and the other main sections cover HRT and breast cancer, endometrial cancer, colon cancer, melanoma and epithelial ovarian cancer. The concluding chapters discuss the benefits and risks of specific therapies. An authoritative clinical reference with extensive bibliographic references and index, Hormone Replacement Therapy and Cancer covers all aspects of HRT and cancer based on the research available up to June 2001.

Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the mammalian brain.
This exciting book brings together leading clinicians and researchers to discuss oestrogen's basic mechanisms of action, the extrahypothalmic brain regions it affects, and its influence on cognitive functions in animals and humans. Finally, recent research on the role of oestrogens in ageing and dementia, including the significance of oestrogen action in Alzheimer's disease, is discussed. The 15 papers contained in this book, together with the extensive discussion sessions that follow them, reveal much new and exciting work in this area, and identify promising new research directions.

Over 2,500 years ago, Hippocrates advocated the personalisation of "nourishment and exercise" as the "safest way to health". He knew that our behaviours influence our health, but he did not know why. This book explains the missing link: the crucial role played by our hormones and what we can do to optimise them. Hormones set in motion the physiological processes that keep us alive, bringing our DNA to life by directing gene expression. Hormones are the protagonists in the interaction between lifestyle and health. We can harness our hormones positively to optimise health through our choice of behaviours. Conversely, mistiming between our actions and internal hormone biological clocks can derail the intricate interactions of hormone networks. For example, in relative energy deficiency in sport (RED-S). This book reveals the clandestine world of hormones, navigating the path to achieving full personal potential, through the different stages of life. This is relevant for both men and women, whatever your objectives, whether you are a high-level athlete; looking to improve health and fitness; seeking to understand hormone disruption; or meeting the challenges of physiological changes in hormones during life such as perimenopause and menopause. Practical tips and "hormone stories" provide actionable advice and real-life examples of how to tune in to your hormones and maintain hormone health. As the human lifespan extends, it becomes ever more desirable to remain healthy into old age. Understanding how and why your choice of lifestyle affects your hormones empowers you to take informed decisions to improve your personal health. A life-long, healthy mix of exercise, nutrition and sleep is open to anyone, at minimal cost.

The much-anticipated new edition of this standard textbook compiles current information on the various integrated areas of endocrinology, physiology, and biology of reproduction in one diverse volume. The text provides a physiological foundation for clinical training and encourages further research by including an extensive listing of references at the end of each chapter. Coverage includes the seven domestic species as well as llamas, alpacas, and vicunas.

Revised and improved, the fifth edition contains:
Cutting-edge information--500rovided by new contributors
A new chapter on South American camelids
Concise text which has been filtered to eliminate redundancy
Upgraded illustrations, including additional color plates and over 100 new figures.

"McDonald's Veterinary Endocrinology and Reproduction" is widely used in veterinary schools throughout the United States and Canada, with the Spanish translation used in Latin America and Spain. This mainstay is an essential part of veterinary and agricultural education.

Neuropalliative Care, Part Two, Volume 191 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important. The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment. Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.

Meet-the-Professor (MTP) Endocrine Case Management, Reference Edition 2021 is your source for the latest updates in the diagnosis and management of a wide range of endocrine disorders. This valuable resource allows you to evaluate your knowledge and gain insight into the strategies used by clinical experts. Updated annually. Customers are advised that this book is a reference edition and the questions in it are designed for self-study and reference. The content is the same as the non-reference edition, but CME and MOC credits are not available upon completion of the material. Anyone with questions about CME and/or MOC credits should consult www.endocrine.org/store for further information.

This innovative textbook provides a readable, contemporary and fully integrated introduction to endocrine glands, their hormones and how their function relates to homeostasis. It explores the pathology of endocrine disease by relating the underpinning science through a wealth of clinical scenarios and examples. The book integrates basic and clinical aspects for a range of endocrine glands and their hormones and includes a number of specialist chapters that also address areas of intense research and clinical interest including the regulation of salt, appetite and endocrine-immune interactions. * Provides a fully-integrated, scientific and clinical introduction to endocrinology. * Includes a wealth of colour illustrations to reinforce key concepts. * Introduces clinical scenarios and leading questions to engage interest and illustrate the relevance of the underpinning science. * Includes key references and suggestions for further reading at the end of each chapter. Written by a highly respected and experienced author team this new textbook will prove invaluable to students needing an original, integrated introduction to the subject across a variety of disciplines including biomedical science, pharmacology , bioengineering and pre-clinical medicine.

This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.

Despite the gains of the women s movement, women are still judged by what they look like--and men, by what they do. Fat--A Fate Worse Than Death? offers hardy resistance to the narrow, random, and irrational appearance standards set for American women through an approach that is personal, eclectic, courageous, and funny. If you are interested in giving up your diet, throwing out your scales, and concentrating on who you are on a deeper level, this book will show you how to accept, appreciate, and even love your body Using statistics, research, anecdotes, and personal experiences, Fat--A Fate Worse Than Death? explores how appearance standards have built a prison for women. With the book s helpful advice, reading suggestions, and list of more than 100 ways to fight looksism, sexism, ageism, and racism, you will learn to express your rights and needs, regardless of your shape or size, and tear down those prison walls. Designed to transcend the boundaries between the personal and the political, Fat--A Fate Worse Than Death? discusses: examples of how weight and size constitute the last socially accepted prejudice the national "War on Fat" counteracting societal influences that support weight preoccupation connection between appearance standards for older women and large women nurturing your body resisting male-defined standards of beauty for women the myth of diets and dieting how the body resists weight loss how women are disempowered by concentration on weight and appearance how concentrating on appearance leaves real-life issues unaddressed how feeling bad about yourself can turn you into a willing consumerFeminists, faculty and students of women s studies programs, aging women, women of radical politics, and other concerned women and men will find that Fat--A Fate Worse Than Death? states explicitly how women are kept powerless by subscribing to cultural and social edicts on physical appearance. Don t live silently in a society that degrades and discounts women because of their physical stature and don t let obsession with thinness keep you passive, docile, and unable to give your energy to things that really need your passion and intelligence. Read this book and learn to not only value yourself for who you are, but also to counteract American culture s equality-denying prejudices and practices."

Resolve the 7 types of hormone imbalance naturally with simple changes to your food and lifestyle habits. Looking for relief from debilitating menstrual cycles, PMS, PMDD, weight gain, low energy, and mood fluctuations caused by a hormonal imbalance, but don't want the side effects and expense of drugs and surgery? Based on therapeutic nutrition principles, The Hormone Type Cookbook gives you accessible solutions to address common hormone imbalances like low progesterone, estrogen dominance, low thyroid, adrenal fatigue, and other issues. Whatever stage of your lifecycle, this guide is your holistic hormone health companion! Expert author Madeline Mackinnon, creator of the popular handle @NaturalHormoneHealing, guides your entire journey of hormonal health, from menstrual health and fertility to postpartum, perimenopause, and menopause. You will finally understand the "why" of your hormone imbalances, not just the "what." Madeline also debunks nutritional myths and shows how certain popular diets can actually disrupt hormone balance. Drawing upon the latest hormone nutrition research, the book contains: Hormone quizzes and assessments, so you can determine your specific imbalance and then eat to treat it The foundations of hormone health How to structure meals to keep your hormones happy Guidance on lifestyle habits and what things in your environment, such as endocrine disruptors, are creating issues All the while, you'll be eating your choice of 75 delicious hormone-supporting breakfasts, lunches, dinners, drinks, and snacks, such as: Hot Flash Elimination Smoothies Thyroid-Loving Lunch Bowl Libido-Boosting Freezer Fudge Stress-Support Matcha Latte Start your healing journey to hormone balance today.