Eutectic Solvents and Stress in Plants, Volume 97 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters surrounding NADES: from simple systems to complex colloidal mixtures, DES nanostructures with water, micelle and DES interaction, Dissolving proteins protein physics, Enzyme reactions in NADES, Protection against oxidation of metabolites, stability food, DES for pharmaceutical preparations, Cosmetics, Metabolons and bio-condensates: the essence of plant plasticity and the key elements in development of green production systems, Immediate in the whole plant during extreme conditions metabolomics, NADES in sees spores, and much more.

Biology of Aminoacyl-tRNA Synthetases, Volume 48 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on A narrative about our work on the endless frontier of editing, The puzzling evolution of aminoacyl-tRNA synthetases, Structural basis of the tRNA recognition by aminoacyl-tRNA synthetases, Catalytic strategies of aminoacyl-tRNA synthetases, Trans-editing by aminoacyl-tRNA synthetase-like editing domains, Adaptive and maladaptive mistranslation arising from aminoacyl-tRNA synthetases, Non-canonical inputs and outputs of tRNA aminoacylation, Structure and function of multi-tRNA synthetase complexes, Mitochondrial aminoacyl-tRNA synthetases, Non-canonical functions of human cytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl-tRNA synthetases, and much more.

The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis.

Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural products derived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients. This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedical field interested in understanding more about natural products with anticancer potential.

Ethics of Everyday Medicine: Explorations of Justice examines and analyses the relatively unexplored domain of ethics involved in the everyday practice of medicine. From the author's clinical experience, virtually every decision made in the day-to-day practice of medicine is fundamentally an ethical question, as virtually every decision hinge on some value judgment that goes beyond the medical facts of the matter. The first part of the book is devoted to medical decision cases in several areas of medicine. These cases highlight elements of the current healthcare ecosystem, involving players other than the physician and patient. Insurers (private, commercial, and governmental), administrators, and regulators' perspectives are surfaced in point of care case analysis. Part two contributes to the development of actionable tools to develop better ethical systems for the everyday practice of medicine by providing a critical analysis of Reflective Equilibrium and ethical induction from the perspective of logic and statistics. The chapter on Justice discusses the neurophysiological representations of just and unjust behaviours. The chapter on Ethical Theories follows, describing the epistemic conundrum, principlism, reproducibility, abstraction, chaos and complexity. The following chapter approaches ethical decisions from the logic and statistic perspectives. The following chapter, The Patient as Parenthetical, the author discusses patient-centric ethics, and the rise of business- and government-cetric ethics. The final chapter, A Framework to Frame the Questions for Explore Further, proposes a working framework to deal with current ethical issues. Ethics of everyday Medicine: Explorations of Justice acknowledges that there are no answers yet to the ethical dilemmas that confront the everyday practice of medicine, but proposes a framework for deeper analysis and action. This reading would be useful to all healthcare professionals. Regulators and policy makers could also benefit from understanding how the complex healthcare environment influences medical decisions at point of care.

Advances in Botanical Research, Volume 96, highlights new advances in the field, with this new volume presenting interesting chapters on the Structure and supramolecular architecture of chloroplast ATP synthase, Chloroplast ATP Synthase from Green Microalgae, Subunit movements in H-ATPases from chloroplasts detected by single molecule FRET, Regulation and control of the chloroplast ATP synthase: mechanisms and impact on maintaining efficient photosynthesis and photoprotection, Regulation machineries of ATP synthase from phototroph, How do we understand the formation of delta-pH in photosynthesis?, Regulation of photosynthesis by cyclic electron transport around photosystem, and the Biogenesis regulation of chloroplast ATP synthase.

Self-assessment Q&A in Clinical Laboratory Science, III, adds a variety of subject matter that addresses new concepts and emerging technology, particularly in the areas of kidney biomarkers, cancer biomarkers, molecular diagnostics, multiple myeloma, pharmacogenomics, novel cardiovascular biomarkers and biomarkers of neurologic diseases. The field of Clinical Laboratory Science continues to evolve and editor Alan Wu has once again brought together experts in the field to cover the contemporary topics that are being tested today. This updated bank of questions and answers is a must-have to sharpen knowledge and skills.

Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual.

Advances in Agronomy, Volume 163, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

Climate Change in the Himalayas: Vulnerability and Resilience of Biodiversity and Forest Ecosystems explores and assesses issues affecting species survival in the rich forests of the Himalayan region. This book characterizes current biodiversity statuses, related ecosystem services, and provides new evidence and solutions for climate change effects on Himalayan animals and plants. Written by regional and international experts on climate change, ecosystems and the Himalayas, this book analyzes current species threats, loss of habitats, and carbon effects. It identifies critical areas requiring special attention and provides workable solutions for protection and ecosystem services. As many plant and animal species continue to be classified as extinct due to climate change, urbanization, and failing ecosystems, analyses and techniques in this book offer resolutions for sustaining current risks and curbing future risks. These can also be applied to other biodiverse, at-risk regions of the world.

Moving away from the long-established paradigm which holds that all political behavior is learned via socialization, this Handbook assesses the contributions of biology to political science, illustrating that behavior is in actual fact shaped by the interplay between learning and biological influences. Describing how a more biologically-oriented approach expands and enriches political science, both conceptually and in terms of its research capabilities, key chapters focus on general biological approaches to politics, biopolitical contributions to mainstream areas within political science, and linkages between biology and public policy. Providing specific examples of how Neo-Darwinism can contribute to more successful public policies, the Handbook further emphasizes the close ties between a realistic understanding of human political behavior and the likelihood that our species successfully resolves the problems that now threaten its welfare. Original and thought-provoking, this Handbook will prove an enriching read for political scientists starting to consider the value of biological factors in influencing political behavior, as well as for behavioural scientists in other areas experiencing the same paradigm shifts. Biologists will also find further grounding for their research into biological and behavioral science. Contributors include: K.Blanchard, Jr., R.H. Blank, D. Boisvert, E. Bucy, K. Butts, P.A. Corning, D. Couvet, A. Fletcher, B.J. Foster, J.M. Friend, A. Friesen, O. Funke, A. Ksiazkiewicz, M. Latner, V. Lemm, L. Liesen, J. Losco, R.D. Masters, A. Mazur, G.R. Murray, W.J. Patzelt, M.B. Petersen, S.A. Peterson, A. Somit, R.H. Sprinkle, P.A. Stewart, B.A. Thayer, J. Vaske, M. Vatter, R.F. White, T.E. Wohlers

Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

Multi-System Imaging Spectrum Associated with Neurologic Diseases covers over 200 classic multi-systemic entities associated with neurologic diseases with detailed discussion alongside illustrative photos for memory aids and clarification. Accompanying text explains the history and meaning of the descriptive or metaphoric sign. Uniquely written from a practical point of view, each case leads you through a radiology expert’s thought process in analyzing imaging pitfalls of different organs or systems. The cases highlight clinical presentation, relevant pathology, anatomy, physiology, and pertinent imaging features of common disease processes. Key information is distilled succinctly, with bulleted, detailed illustrations and images.

Effective use of Social Media in Public Health offers a well-organized and comprehensive review of social media and its impact on people’s lives and the public health sector. Divided into sections, the book addresses the growing use (and importance) of social media in conducting and disseminating research findings and covers an array of issues from cyberbullying to diversity and inclusion. Written by health educators and practitioners for health educators and practitioners, this book is a timely resource on the topics discussed.

Theory of Endobiogeny, Volume 3: Advanced Concepts for Treatment of Complex Clinical Conditions explains complex and multi-factorial disorders and diseases using the theory of endobiogeny. It provides detailed applications of biological modeling, in-depth assessment into common disorders, an endobiogenic analysis, guidance on using biological modeling tools, and suggestions for treatment using standard of care treatments that also take into account diet, lifestyle and medicinal plants. This approach is an evolution in thinking from reductionism to holism, offering advice for symptomatic treatments that can be used in conjunction with a new way of thinking about diseases and disease management.

The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia.

Advances in Agronomy, Volume 156, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation.

The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.

The lymphatic system develops and functions in parallel with the blood circulatory system (termed the "hemovasculature") and accomplishes transport of interstitial fluids, dietary lipids, and reverse transport of cholesterol, immune cells, and antigens-providing a critical homeostatic fluid balance and transmission of immune cells and mediators back to the cardiovascular system. Although the daily flow of lymph (normally 1-2 L/day under unstressed conditions) is far lower than that of daily blood flow (which is 7,500 L/day), without the adequate functioning of the lymphatics, virtually all organs and tissues would acutely suffer many different physical and inflammatory stresses ranging from edema to organ system failure. Although blood and lymphatic vessels often form in anatomic parallels to one another, our knowledge of the workings of the lymphatic system, the fine structure of lymphatic networks, how they function in different organs, and how they are regulated physiologically and immunologically are far from parallel; our knowledge of the lymphatic system still remains at only a tiny fraction of what is understood about the cardiovascular system. Although both the cardiovascular and lymphatic systems are important transport systems, what they transport and how they transport and propel these very different cargoes could not be more dissimilar. This book provides an overview of the history of the discovery (and re-discovery) of the components of the lymphatic system, lymphatic anatomy, physiological functions of lymphatics, molecular features of the lymphatic system, and clinical perspectives involving lymphatics which may be of interest to scientists, clinicians, patients, and the lay public. We provide a current understanding of some of the more important structural similarities and differences between lymphatics and the blood vascular system, their coordinated control by angiogenic and hemangiogenic growth factors and other modulators, the fate and lineage determinants which control lymphatic development, and the roles that lymphatics may play in several different diseases.

Epigenetics and Breeding, Volume 88, the latest release in the Advances in Botanical Research series, brings together the experiences and critical information teachers, researchers and managers must consider from both scientific and legal points-of-view as they relate to biotechnology. New chapters in this updated volume include sections on Epigenetic Mechanisms in Plants, Epigenomic Diversity and Applications to Breeding, Epigenetics in Breeding, EpiRILs: Lessons from Arabidopsis, Transposable Elements as a Tool for Plant Improvement, Epigenome Editing, Epigenetics and Grafting, Sexual and Non-sexual reproduction, Epigenetics in Cereals, and more.

Cancer Therapy and Diagnosis, Part B, Volume 44 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN).

This collaboration of two physiologists and a gastroenterologist provides medical and graduate students, medical and surgical residents, and subspecialty fellows a comprehensive summary of digestive system physiology and addresses the pathophysiological processes that underlie some GI diseases. The textual approach proceeds by organ instead of the traditional organization followed by other GI textbooks. This approach lets the reader track the food bolus as it courses through the GI tract, learning on the way each organ's physiologic functions as the bolus directly or indirectly contacts it. The book is divided into three parts: (1) Chapters 1-3 include coverage of basic concepts that pertain to all (or most) organs of the digestive system, salivation, chewing, swallowing, and esophageal function, (2) Chapters 4-6 are focused on the major secretory organs (stomach, pancreas, liver) that assist in the assimilation of a meal, and (3) Chapters 7 and 8 address the motor, transport, and digestive functions of the small and large intestines. Each chapter includes its own pathophysiology and clinical correlation section that underscores the importance of the organ's normal function.

Effect of High-Pressure Technologies on Enzyme: Science and Applications provides a deep, practical discussion of high-pressure processing (HPP) and high-pressure homogenization (HPH) technologies and biochemical approaches, applied across research and industry, with applications ranging from food to pharmaceuticals and commercial enzyme production. Early chapters discuss foundational aspects of HPP and HPH approaches; the science of enzyme modification; and basic aspects of enzyme activity, stability, and structure as studied in biochemical processes. Later chapters consider the effect of HPP and HPH technologies and their mechanisms of controlling enzyme modification to improve enzyme performance for chosen applications. Special attention is paid to the application of HPP and HPH technologies and enzyme modifications in food processing, microbial enzyme modification, drug discovery, and production of other commercial enzymes, as well as the challenges of undesirable enzyme inactivation. The final chapter discusses future directions of the field and technologies, and expanded applications.