Nanobiotechnology in agriculture is a new knowledge area that offers novel possibilities to achieve high productivity levels at manageable costs during the production and merchandising of crops. This book shows us how we can use the cutting-edge knowledge about agriculture, nanotechnology, and biotechnology to increase the agricultural productivity and shape a sustainable future in order to increase the social welfare in rural areas and preserve the environmental health. Specialists from several countries will provide their feedback on a range of relevant topics such as environment-friendly use of nanofertilisers, nanodevices, nano-food packaging, nanocoating and nanocarriers and their relationship with the modern agriculture.

Fungi playa major role in the sustainability of the biosphere, and mycorrhizal fungi are essential for the growth of many of our woods and forests. The applications of fungi in agriculture, industry and biotechnology remain of paramount importance, as does their use as a source of drugs and to help clean up our environment. This volume contains key papers from the conference 'From Ethnomycology to Fungal Biotechnology: Exploiting Fungi from Natural Resources for Novel Products'. This was the first international scientific conference covering the transfer of traditional remedies and processes in ethnomycology to modern fungal biotechnology. The conference was held at Simla, Himachal Pradesh, India from 15 to 16 December 1997. The key subject areas addressed in the conference were the issues of exploring and exploiting fungal diversity for novel leads to new antibiotics, enzymes, medicines and a range of other leads for wood preservation, biological control, agricultural biotechnology and the uses of fungi in the food industry. The conference programme included key-note presentations followed by poster sessions and general discussion. The book is broadly based, covering five main areas: Ethnomycology, Fungal Biotechnology, Biological Control, Mycorrhizal Fungi and Fungal Pests. There is no doubt that in the past fungi have played a key role in ethnomycological remedies and that in the future they will continue to attract the interest of a wide range of disciplines ranging from environmental conservation, agriculture and the food industry to wood preservation and aerobiological studies.

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult.

The aim of this book is to present the current state of the art of extracting natural products with near-critical solvents and to view the possibilities of further extensions of the technique. Relevant background theory is given but does not dominate the book. Carbon dioxide is the near-critical solvent used in most recent applications and inevitably receives prominence. In addition to general descriptions and reviews, the book contains three chapters by indus trial practitioners who describe in detail the operation of their processes and discuss the market for their products. Sections on the design of the pressure vessels and pumps required in these processes and on the acquisition of the data required for design are included. The costing of the processes is also discussed. There is good scope for combining a near-critical extraction step with other process steps in which the properties of near-critical solvents are utilised, for example as a reaction or crystallisation medium and a chapter is devoted to these important aspects. It is hoped that the work will be found to contain a great deal of specific information of use to those already familiar with this field. However the style of presentation and content is such that it will also be useful as an introduction. In particular it will be helpful to those wondering if this form of separation method has anything to offer for them, whether they are engineers, chemists or managers in industry, or in academic or research institutions."

This groundbreaking book is the first comparative analysis of the relative strengths of global bioregions. Growth Cultures investigates the rapidly growing phenomena of biotechnology and sets this study within a knowledge economy context. Philip Cooke proposes a new knowledge-focused theoretical framework, 'the New Global Bioeconomy', against which to test empirical characteristics of biotechnology. In this timely volume, Cooke unifies concepts from the sociology of science, economic sociology and evolutionary economic geography to focus on the problems and prospects for policy agencies worldwide trying to build 'biotechnology clusters'. He develops a superior policy approach of thinking in terms of platforms that integrate proximities and pipelines, which will be of significant interest for the scientific and technological communities as well as economic development policy communities. Growth Cultures will make fascinating reading for students, policy makers and researchers across management and business studies, innovation and knowledge studies, sociology, science and technology policy, applied economics, development studies and regional science.

The current book describes the chemical and physical behaviour of polymers and biopolymers that form highly associating structures in equilibrium solution. It summons the established results known of polymer complexes in solution, taking into account also the recent developments in biotechnology concerning this topic, in technological applications of polymer-protein interactions, in fluorescence and scattering techniques for the study of intra- and interpolymer association and in the study of ionomers in solution. The book covers the whole range from synthesis and fundamental aspects to applications and technology of associated polymers.

This book offers a comprehensive review on biomass resources, examples of biorefineries and corresponding products. The first part of this book covers topics such as different biorefinery resources from agriculture, wood processing residues and transport logistics of plant biomass. In the second part, expert contributors present biorefinery concepts of different biomass feedstocks, including vegetable-oils, sugarcane, starch, lignocellulose and microalgae. Readers will find here a summary of the syngas utilization and the bio-oil characterization and potential use as an alternative renewable fuel and source for chemical feedstocks. Particular attention is also given to the anaerobic digestion-based and Organosolv biorefineries. The last part of the book examines relevant products and components such as alcohols, hydrocarbons, bioplastics and lignin, and offers a sustainability evaluation of biorefineries.

The scope of the field of biotechnological processes is very wide, covering such processes as fermentations for production of high-valued specialist chemicals (e.g. pharmaceuticals), high-volume production of foods and feeds (e.g. yoghurt, cheese, beer), as well as biological waste treatment, handling solid (composting), liquid (activated sludge) and gaseous wastes (biofilters). Compared to other engineering disciplines, the introduction of modern optimization and control strategies is lagging behind. Two main reasons can be identified. First, the living organisms (or part thereof) that are central to these processes make the mathematical modeling of the processes a difficult task, and, since models are central to the development of control systems, the on-line control problem is also complex. The other difficulty stems from the absence, in most cases, of cheap and reliable instrumentation suited to real-time monitoring. In this book a number of advanced techniques is introduced to deal with these problems. In the first part modern on-line hardware sensors are discussed in detail (FIA, viable biomass measurement, membrane inlet mass spectrometry, flow cytometry, microcalorimetry). In the second part, novel model-based process diagnosis and control techniques are dealt with, including advances in bioprocess modeling and identification, data processing, software sensor design, and on-line control algorithms. The book is directed at engineers, researchers, and students in the field of process control and systems theory as applied to industrial biotechnological processes, as well as at bioengineers who have some background in control engineering and wish to increase their understanding ofhow advanced control theory applies to biological processes.

The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.

At the dawn of the 21st century, biotechnology is emerging as a key enabling technology for sustainable environmental protection and stewardship. Biotechnology for the Environment: Strategy and Fundamentals captures the dynamism of environmental biotechnology as it addresses the molecular functioning of microorganisms as cleanup agents, their communal interactions in natural and polluted ecosystems, and the foundations of practical bioremediation processes. Chapters on biological pollution control in the chemical industry, biodegradation of persistent molecules (halogenated compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, pesticides, detergents, etc.), microbial diversity with impact on global change, bioaugmentation strategies, and sensors for ecotoxicological monitoring, will be of value to environmental scientists, engineers, and decision-makers involved in the development, evaluation, or implementation of biological treatment systems.

For information on Soil Remediation, see Focus on Biotechnology volume 3B, and for information on Waste Water and Waste Gas Handling, see Focus on Biotechnology volume 3C.

"This monograph contains recent studies in eco-informatics, promising ideas "

"and new challenges in information management for supporting sustainability in"

"companies and other organization. The scope of this book includes sets of"

"solutions which show different stakeholders viewpoints on sustainability. ""In individual chapters, authors discuss the role which Environmental"

"Information Systems (EIS) play in the environmental conscious functioning of"

"enterprise. New models, methods and tools supporting sustainability are"

"presented. Emphasis is placed on the innovative approach to eco-friendly"

"organization and coordination of transport, logistics processes and operations"

"management. The information management and decision making in"

"manufacturing and service organizations is highlighted."

"The scope of this monograph also encompasses topics related to the modeling"

"and monitoring of climate change.""

"

Antimicrobial Activity of Nanoparticles: Applications in Wound Healing and Infection Treatment presents the state of the art among nanotechnological approaches used in the treatment of infections. This field has gained a large amount of interest over the past few years, in response to the increasing resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The book covers various aspects: from antiviral and antibacterial nanoparticles, to the functionalization of nanoparticles and their toxicity to human cells. This book offers an advanced reference text for biomedical engineers, materials scientists, clinicians, and biochemists, with an interest in nanomedicine and infection control.

Since its first systematic application during the 1970s, bioremediation, or the exploitation of a biological system's degradative potential to combat toxic pollutants such as heavy metals, polyaromatic hydrocarbons (PAH), cyanides, and radioactive material, has proven itself over time, and the many advances in molecular techniques have only amplified its utility. In Bioremediation: Methods and Protocols, experts in the field explore imaginative and ambitious multidisciplinary techniques that will enable more predictable removal of pollutants from a variety of environments. The easy-to-follow volume addresses some of the broader issues such as the effect of the environment in determining the availability and fate of organic and inorganic compounds and how choices around the most appropriate bioremediation process can be arrived at, as well as detailed complementary techniques that support the effective deployment and monitoring of a bioremediation approach. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Bioremediation: Methods and Protocols offers researchers a series of invaluable techniques certain to enhance their work with environmental contamination."

This revised third edition of Rheology of Fluid, Semisolid, and Solid Foods includes the following important additions: * A section on microstructure * Discussion of the quantitative characterization of nanometer-scale milk protein fibrils in terms of persistence and contour length. * A phase diagram of a colloidal glass of hard spheres and its relationship to milk protein dispersions * Microrheology, including detailed descriptions of single particle and multi-particle microrheological measurements * Diffusive Wave Spectroscopy * Correlation of Bostwick consistometer data with property-based dimensionless groups * A section on the effect of calcium on the morphology and functionality of whey protein nanometer-scale fibrils * Discussion of how tribology and rheology can be used for the sensory perception of foods

Increasing population and industrialization are the key pollutant contributors in water bodies. The wastes generated by industries are highly hazardous for humans and the ecosystem and require a comprehensive and effective treatment before being discharged into water bodies. Over the years, many up gradations have been introduced in traditional water treatment methods which were expensive and ineffective especially for removal of toxic pollutants. Phycoremediation has been gaining attention due to its mutual benefit in wastewater treatment and for valuable algae biomass production. Wastewater, especially sewage and industrial effluents, is rich in pathogenic organisms, organic and inorganic compounds and heavy metals that adversely affect human and aquatic life. Microalgae use these inorganic compounds and heavy metals for their growth. In addition, they also reduce pathogenic organisms and release oxygen to be used by bacteria for decomposition of organic compounds in a secondary treatment. In this book, the potential of microalgae in wastewater treatment, their benefits, strategies, and challenges are discussed. The increasing need of finding innovative, low-cost, low-energy, sustainable and eco-friendly solutions for wastewater treatment makes the publication of a book on phycoremediation timely and appropriate. Features: (1) Deals with the most emerging aspects of algal research with special reference to phycoremediation. (2) Studies in depth diversity, mutations, genomics and metagenomics study (3) An eco-physiology, culturing, microalgae for food and feed, biofuel production, harvesting of microalgae, separation and purification of biochemicals.

Microbes and Microbial Biotechnology for Green Remediation provides a comprehensive account of sustainable microbial treatment technologies. The research presented highlights the significantly important microbial species involved in remediation, the mechanisms of remediation by various microbes, and suggestions for future improvement of bioremediation technology. The introduction of contaminants, due to rapid urbanization and anthropogenic activities, into the environment causes unsteadiness and distress to the physicochemical systems, including living organisms. Hence, there is an immediate global demand for the diminution of such contaminants and xenobiotics which can otherwise adversely affect the living organisms. Over time, microbial remediation processes have been accelerated to produce better, eco-friendlier, and more biodegradable products for complete dissemination of these xenobiotic compounds. The advancements in microbiology and biotechnology lead to the launch of microbial biotechnology as a separate area of research and contributed dramatically to the development of the areas such as agriculture, environment, biopharmaceutics, and fermented foods. Microbes stand as an imperative, efficient, green, and economical alternative to conventional treatment technologies. The proposed book provides cost-effective and sustainable alternatives. This book serves as a reference for graduate and postgraduate students in environmental biotechnology and microbiology as well as researchers and scientists working in the laboratories and industries involved in research related to microbiology, environmental biotechnology, and allied research.

Industrial Hemp: Food and Nutraceutical Applications is a comprehensive overview of different value chains for the industrial hemp industry. This excellent reference supports multi-disciplines and presents industrial hemp as a multi-purpose crop, with special attention paid to its food and nutraceutical applications. By combining and presenting multidisciplinary knowledge, readers will be introduced to recent progress in hemp production, processing, utilization and marketing. The book provides a systematic overview of alternative hemp applications, but also serves as a guide to the challenges needed for hemp revitalization to reach its fullness.

The first volume in a series which aims to focus on advances in computational biology. This volume discusses such topics as: fluctuations in the shape of flexible macromolecules; the hydration of carbohydrates as seen by computer simulation; and studies of salt-peptide solutions.

In dealing with recent advances in biological engineering and human reproduction, we are confronted with legal, ethical, and religious questions for which there are no precedents. Warren Freedman undertakes a comprehensive examination of this topic. Sorting through the tangle of issues surrounding artificial insemination, surrogate motherhood, and other aspects of contemporary reproduction trends, Freedman attempts to clarify the rights and responsibilities of individuals, families, and society in the face of these new developments.

The author begins with a survey of the legal implications of nontraditional approaches to conception and birth. Separate chapters are devoted to artificial insemination and surrogate motherhood; and new concepts such as cryo-preservation, in-vitro fertilization, banking of sperms and eggs, and patentable new organisms are also discussed in detail. The author addresses questions of rights and liabilities as they apply to fetuses, donors, and adoptive parents, as well as the role of physicians and parenthood organizations, researchers, corporations, and government. Following a review of existing statutes, policies, and contracts that attempt to deal with these issues both here and abroad, he presents proposals that may aid in achieving equitable, uniform solutions. Freedman's book will be of interest to any citizen, group, or government agency concerned with these vital questions, and to professionals in law, government, medicine, human services, and industry.

This volume details the exploration, collection, characterization, evaluation and conservation of microbes for sustainable utilization in the development of the global as well as national economies, e.g. in agriculture, ecosystems, environments, industry and medicine.Many research institutes and universities all over the world carry out microbiological and biotechnological research, which generates substantial genomic resources such as cDNA libraries, gene constructs, promoter regions, transgenes and more valuable assets for gene discovery and transgenic product development. This work provides up-to-date information on the management of microbial resources in the environment. It also covers the ecology of microorganisms in natural and engineered environments. In trying to understand microbial interactions it further focuses on genomic, metagenomic and molecular advances, as well as on microbial diversity and phylogeny; ecological studies of human, animal and plant microbiology and disease; microbial processes and interactions in the environment; and key technological advances. Though not intended to serve as an encyclopedic review of the subject, the various chapters investigate both theoretical and practical aspects and provide essential basic information for future research to support continued development. "

The purpose of this book is to provide a balanced introduction to process control and management, aimed at the general process engineer. Rapid changes have occurred in process control over the past decade, mainly because of the deployment of robust and effective digital control equipment, and the development of the models which underpin the area. Historically, process control was seen as simply the maintenance of particular process variables at appropriate setpoints. This very narrow view has been superseded by the view that process control involves the regulation of any given process, in the context of a complete processing plant, to maximise the economic return from the plant. This wider definition brings into play a range of control regimes, from basic regulatory control, through advanced regulatory control, to complex process management. The organization of the book reflects this hierarchy, and is thus split into 3 parts, covering basic regulatory control, advanced process control and finally process management. The book is completed by the inclusion of several useful appendices, covering mathematical modelling, process optimisation and simulation.

Bioenergy: Principles and Technologies introduces biomass energy resources and then elaborates on bioenergy technologies including biomass combustion, biogas production, biomass briquettes and biomass gasification. With a combination of theories, experiments and case studies, the book is an essential reference for bioenergy researchers, industrial chemists and chemical engineers.