This book is about Saffron (Crocus sativus L.) that is the most expensive spice in the world. Though there are other books on saffron but none of them has comprehensive information on saffron genome, transcriptome, proteome, metabolome and microbiome. The book has been divided into five sections and 17 chapters that cover all the areas related to its cultivation, market & economy, genomics, transcriptomics, proteomics, metabolomics, tissue culture, microbiomics, metagenomics etc. In addition a chapter on molecular markers and their use in molecular genetic mapping in saffron that lacks genetic diversity as a sterile plant paves a way for selection of elite varieties based on the epigenetic variability. A section on in-vitro propagation elaborates on the corm production under controlled conditions. In summary this book encompasses most of the information available on this golden spice

This book provides that knowledge needed to introduce individuals to the most important research and content on nanotoxicology in nanobiomedicine. Nanotechnology is helping to considerably improve, even revolutionize many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. There is an urgent need for a general reference textbook that presents the most recent information on the toxicity and its effects in all these sectors, biomedicine in particular. It includes historical information, nanotoxicology by subject area and or disease, sources of nanomaterials, drug delivery systems and more. Scientists, researchers, and students in all fields that use nanotechnology will find this book essential reading.

The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012. It provides not only a platform for domestic and foreign researchers to exchange their ideas and experiences with the application-oriented research of biotechnology, but also an opportunity to promote the development and prosperity of the biotechnology industry. The proceedings of ICAB 2012 mainly focus on the world's latest scientific research and techniques in applied biotechnology, including Industrial Microbial Technology, Food Biotechnology, Pharmaceutical Biotechnology, Environmental Biotechnology, Marine Biotechnology, Agricultural Biotechnology, Biological Materials and Bio-energy Technology, Advances in Biotechnology, and Future Trends in Biotechnology. These proceedings are intended for scientists and researchers engaging in applied biotechnology. Professor Pingkai Ouyang is the President of the Nanjing University of Technology, China. Professor Tongcun Zhang is the Director of the Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education at the College of Bioengineering, Tianjin University of Science and Technology, China. Dr. Samuel Kaplan is a Professor at the Department of Microbiology & Molecular Genetics at the University of Texas at Houston Medical School, Houston, Texas, USA. Dr. Bill Skarnes is a Professor at Wellcome Trust Sanger Institute, United Kingdom.

Principles and Practice of Bioanalysis provides a guide to the methods available and the techniques currently used in this field. It provides up to the minute information and guidance on the methods and strategy used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The authors writes in an informal and didactic style, offering a logical path through the problems of small molecule (bio)analysis and enables readers to choose appropriate methods of analysis for their needs. Principles and Practice of Bioanalysis gives an overview of analytical methods for analytical scientists within the pharmaceutical industry, research and development, the agrochemical industry, and scientists in the health service, biology and biochemistry. It also gives postgraduate students a useful reference for their research methods.

Heterosis and Hybrid Seed Production in Agronomic Crops discusses how heterosis or "hybrid vigor" has played a major role in improving crop productivity and quality in order to feed the ever-increasing human population, particularly in developing countries. Plant breeders, agronomists, seed producers, and farmers will discover why the development of hybrids in the world's major food crops and why the methods of hybrid seed production are critical for achieving this goal. This landmark book deals with heterosis and hybrid seed production of major agronomic crops such as wheat, rice, maize, sorghum, cotton, sunflower, and rapeseed. Through Heterosis and Hybrid Seed Production in Agronomic Crops, you will discover valuable information on hybrid seed production methods that is not available in any other single volume. This unique book contains relevant and essential information about important procedures to help increase crop yield, including: methods for derivingsecond cycle inbred lines for hybrid maize possibilities for hybrid seed production in wheat techniques of hybrid sorghum seed production production of hybrid seeds using male sterile lines of cotton agronomic management in seed production plots of sunflower seed production technology of hybrid rapeseed advances in hybrid seed production technology of rice in ChinaHeterosis and Hybrid Seed Production in Agronomic Crops gives you a global perspective on essential food crops in all parts of the world. This informative guide will help you use hybrid seed production methods with important agricultural crops and increase the quality of these vital and essential food sources.

Reports up-to-date research developments on purifying and isolation large organic molecules. The text provides information on high-performance liquid chromatography and capillary electrophoresis (CE) as tools for analyzing biomacromolecules and developing new biochemical and medicinal compounds. It applies biochemical separation technology to the study of macromolecules such as proteins, polysaccharides, nucleic acids and more.

Contents:
1. Porphyridium Cruentum Zvi Cohen 2. Monodus Subterraneus Zvi Cohen 3. Production of Eicosapentaenoic Acid by the Marine Eustigmatophyte Nannochloropsis A. Sukenik 4. Production of EPA from Phaeodactylum Tricornumtum E. Molina Grima, F. Garcia Camacho and F. Acien Fernandez 5. Genetic Improvement of the EPA Content in Microalgae Diego Lopez Alonso and Clara I. Segura Del Castillo 6. Recovery of Algal PUFAs E. Molina Grima, A. Robles Medina and Gimenez Gimenez 7. Microalgal Carotenoids Synnove Liaaen-Jensen and Einar Skarstad Egeland 8. Production of Astaxanthin by Haematococcus Yuan-Kun Lee and Dao-Hai Zhang 9. Production of ß-carotene from Dunaliella Ami Ben-Amotz 10. Chemicals of Botryococcus Braunii P. Metzger and C. Largeau 11. Phycobiliproteins Alexander N. Glazer 12. Polysacharides of Red Microalgae Shoshana (Malis) Arad 13. Polyhydroxyalkanoates Massimo Vincenzini and Roberto de Philippis 14. Pharmaceutical and agrochemical from microalgae Michael A. Borowitzka 15. Physiological Principles and Modes of Cultivation in mass Production of Photoautotrophic Microalgae Amos Richmond 16. Economic Evaluation of Microalgal Processes and Products Michael A. Borowitzka

This important reference book is the first comprehensive resource worldwide that reflects research achievements in date palm biotechnology, documenting research events during the last four decades, current status, and future outlook. This book is essential for researchers, policy makers, and commercial entrepreneurs concerned with date palm. The book is invaluable for date palm biotechnology students and specialists. This monument is written by an international team of experienced researchers from both academia and industry. It consists of five sections covering all aspects of date palm biotechnology including A) Micropropagation, B) Somaclonal Variation, Mutation and Selection, C) Germplasm Biodiversity and Conservation, D) Genetics and Genetic Improvement, and E) Metabolites and Industrial Biotechnology. The book brings together the principles and practices of contemporary date palm biotechnology. Each chapter contains background knowledge related to the topic, followed by a comprehensive literature review of research methodology and results including the authors own experience including illustrative tables and photographs."

Biotechnology: Quality Assurance and Validation provides a practical, detailed discussion of what issues Quality Assurance and Quality Control need to identify for effective control in the preparation of biotechnology products. The book presents a series of topics that define some of the unique challenges facing biotechnology companies in producing biopharmaceutical products. The topics selected address quality and validation issues, starting with the cryopreservation of cell lines through the filling and finishing of the product. It includes a validation guide, a clear presentation of how to use filtration effectively, a synoptic view of cleaning procedures, and much more.

Predictive control is a powerful tool in dealing with those processes with large time delays. Generalized Predictive Control (GPC) is the most popular approach to the subject, and this text discusses the application of GPC starting with the concept of long-range predictive control and its need in medicine (particularly automated drug deliveries). The concept of adaptation is also emphasized with respect to patient-to-patient parameter variations. Subsequent chapters discuss interactions, comparisons and various aspects of GPC. The book concludes by putting into perpective the generic nature of the architecture built around GPC and which provides model-based fault diagnosis with control.

This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications. Features summary tables presenting at-a-glance information on practices of recombinant DNA methodologies! Recombinant DNA Principles and Methodologies discusses basic and advanced topics requisite to the employment of recombinant DNA technology, such as -plasmid biology -nucleic acid biochemistry -restriction enzymes -cloning strategies -gel electrophoresis -southern and northern blotting -preparation of probes -phage lambda biology -cosmids and genome analysis -cloned gene expression -polymerase chain reaction -conventional and automated DNA sequencing -site-directed mutagenesis -and more! Elucidating the material with over 2250 edifying references, equations, drawings, and photographs, this state-of-the-art resource is a valuable hands-on guide for molecular and cell biologists, biochemists, bioprocess technologists, applied and industrial microbiologists, virologists, geneticists, chemical engineers, and upper-level undergraduate and graduate students in these disciplines.

All the information necessary to set up and run a tissue culture facility is provided in this introductory book.; ; Includes an overview of all the basic tissue culture techniques and describes in detail both the theoretical background and the practical a

This book contains most of the scientific contributions during the 48th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), which was held electronically in July 2021. It includes multidisciplinary contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians and covers covers all aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence.

The book discusses the importance of eggplant (Solanum melongena L.) as a crop, highlighting the potential for eggplant to serve as a model for understanding several evolutionary and taxonomic questions. It also explores the genomic make-up, in particular in comparison to other Solanaceous crops, and examines the parallels between eggplant and tomato domestication as well as between the most common eggplant species and two related eggplants native to Africa (Ethiopian eggplant [Solanum aethiopicum L.] and African eggplant [Solanum macrocarpon L.]). The eggplant genome was first sequenced in 2014, and an improved version was due to be released in 2017. Further investigations have revealed the relationships between wild species, domesticated eggplant, and feral weedy eggplant (derived from the domesticate), as well as targets of selection during domestication. Parallels between eggplant and tomato domestication loci are well known and the molecular basis is currently being investigated. Eggplant is a source of nutrition for millions of people worldwide, especially in Southeast Asia where it is a staple food source. Domesticated in the old world, in contrast to its congeners tomato and potato, the eggplant is morphologically and nutritionally diverse. The spread of wild eggplants from Africa is particularly interesting from a cultural point of view. This book brings together diverse fields of research, from bioinformatics to taxonomy to nutrition to allow readers to fully understand eggplant's importance and potential.

In order to feed the world, global agriculture will have to double food production by 2050. As a result, the use of soils with fertilizers and pesticides in agronomic ecosystems will increase, taking into account the sustainability of these systems and also the provision of food security. Thus, soil ecosystems, their health, and their quality are directly involved in sustainable agronomical practices, and it is important to recognize the important role of soil microbial communities such as mycorrhizal fungi, their biodiversity, interactions, and functioning. Soil ecosystems are under the threat of biodiversity loss due to an increase of cultivated areas and agronomic exploitation intensity. Also, changes in land use alter the structure and function of ecosystems where biodiversity is vital in the ecosystem. Soils are a major aid in food production in all terrestrial ecosystems; however, this means they are also involved in gas emission and global warming. Thus, in agronomic ecosystems, several mitigation practices have been proposed to promote the increase of carbon soil stock, and the reduction of warming gas emission from soils. In South America, most of the rural population depends economically on agriculture and usually works in family units. New, organic, safe, and sustainable agro-forestry practices must be applied to support local communities and countries to achieve hunger eradication, rural poverty reduction, and sustainable development. This book compiles new information for mycorrhizal occurrence in natural and anthropic environments in South America. It includes new reports of mycorrhizal fungi diversity along different mycorrhizal types and their effect on plant communities, plant invasions, the use of mycorrhizal fungi for ecological and sustainable studies, management programs of natural and agroecosystems, and forestry and food-secure production. This book fills the gaps in biodiversity knowledge, management and safe food production of mycorrhizas. It should be a valuable help to researchers, professors and students, to aid in use of mycorrhizal fungi while also focusing on their biodiversity, sustainable safe food production, and conservation perspectives.

Molecular farming in plants is a relatively young subject of sciences. As plants can offer an inexpensive and convenient platform for the large-scale production of recombinant proteins with various functions, the driven force from the giant market for recombinant protein pharmaceuticals and industrial enzymes makes this subject grow and advance very quickly. To summarize recent advances, current challenges and future directions in molecular farming, international authorities were invited to write this book for researchers, teachers and students who are interested in this subject. This book, with the focus on the most advanced cutting-edge breakthroughs, covers all the essential aspects of the field of molecular farming in plants: from expression technologies to downstream processing, from products to safety issues, and from current advances and holdups to future developments.

This volume contains the proceedings of the Eighth International Symposium on Cyclodextrins, held in Budapest, Hungary, March 31-April 2, 1996. The 147 papers collected here are milestones in the exponentially increasing cyclodextrin literature, and represent a summary of the last two years' achievement in this field, with applications in such diverse disciplines as pharmaceuticals, food, cosmetics, textiles, plastics, and chromatography. Some highlights: lipophilicity profiles of cyclodextrins by computer molecular graphics; recent toxicological studies on cyclodextrins; Buckminsterfullerene/cyclodextrin complexes; hydroxypropyl-beta-cyclodextrin; pharmacokinetics and toxicology; peracylated cyclodextrins as drug carriers; cyclodextrins in nasal drug delivery; textile fibre surface modification by a reactive cyclodextrin; cyclodextrin-containing fabric care products; drug targeting by cyclodextrin-dimers for photodynamic cancer therapy; cyclodextrins in ophthalmologic drugs; new cyclodextrin derivatives and their potentials. Audience: This book will be of interest to researchers whose work involves pharmaceuticals, food chemicals and flavours, food additives, chromatographic methods, and biotechnology, as well as fundamental cyclodextrin research.

Biotic stresses cause yield loss of 31-42% in crops in addition to 6-20% during post-harvest stage. Understanding interaction of crop plants to the biotic stresses caused by insects, bacteria, fungi, viruses, and oomycetes, etc. is important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding and the recently emerging genome editing for developing resistant varieties in technical crops is imperative for addressing FHEE (food, health, energy and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing have facilitated precise information about the genes conferring resistance useful for gene discovery, allele mining and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to biotic stresses. The 15 chapters dedicated to 13 technical crops and 2 technical crop groups in this volume will deliberate on different types of biotic stress agents and their effects on and interaction with crop plants; will enumerate on the available genetic diversity with regard to biotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; will brief on the classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; will enunciate the success stories of genetic engineering for developing biotic stress resistant varieties; will discuss on molecular mapping of genes and QTLs underlying biotic stress resistance and their marker-assisted introgression into elite varieties; will enunciate on different emerging genomics-aided techniques including genomic selection, allele mining, gene discovery and gene pyramiding for developing resistant crop varieties with higher quantity and quality; and will also elaborate some case studies on genome editing focusing on specific genes for generating disease and insect resistant crops.

Biotechnology Entrepreneurship: From Science to Solutions fills a critical gap in the biotechnology industry. For all the resources on how to start companies and on how to manage established companies in other sectors, there is a dearth of material on unique and critical issues in starting biotechnology companies, as well as managing the transition from start-up to established company. It is to this gap that Biotechnology Entrepreneurship is directed. By combining the voices of a diverse set of industry insiders with extensive experience in biotechnology, Biotechnology Entrepreneurship prepares nascent founders, managers, investors, and other biotechnology company stakeholders to position themselves and their companies for commercial success.

Nano-enabled Sustainable and Precision Agriculture is the first single-volume resource to cover this important field using a whole systems approach that considers both opportunities and challenges. The book provides a comprehensive understanding of the role of nanotechnology in agriculture from broad aspects, but also includes a comprehensive view of the interaction of nanomaterials with soil-plant systems. It highlights aspects not described in previous books, including the application of nanoinformatics and artificial intelligence in nano-enabled sustainable agriculture, the application of nanotechnology in alternative forms of agriculture such as hydroponics, and regulatory frameworks for this research field. The book addresses all these aspects by including sections on enhanced sustainability, reduced pollution and enhanced ecosystems' health, and the role of nanoinformatics and machine learning.

This book discusses recent trends and concepts in the field of biorefinery. It discusses optimal and economic strategies for converting biomass to value-added products to maximize profits with minimal environmental impact with a sustainability approach. The chapters of the book are focused on the current technologies, techno-economical aspects, life cycle assessment, and case studies. The book is divided into three sections; the first section presents strategies for the production of biofuels like bioethanol, biomethane, biohydrogen, bio-oil, gasification, etc., from the biomass in a sustainable way. The second sections review the extraction of bioactive chemicals, phenolic antioxidants, enzymes, and carboxylic acid from the biomass residue. The last section examines the utilization of biomass for the production of bioactive materials, including biofertilizers, bioadsorbents, activated carbon, nano-materials, and pigments. This book explores the relation between biofuels and the sustainable development goals (SDGs) 7.

The main driving force behind the development of new applications for chitin and its derivative chitosan lies with the fact that these polysaccharides represent a renewable source of natural biodegradable polymers. Since chitin is the second most abundant natural polymer, academic as well as industrial scientists are faced with a great challenge to find new and practical applications for this material. This book provides an examination of the state of the art, and discusses new applications as well as potential products. Applications of Chitin and Chitosan deals almost exclusively with applications. Previous books in the field have devoted less than 30% of their material to commercial or medical uses.
In the past thirty years, substantial progress has been made on fundamental and applied research in chitosan technology. One of the driving forces behind this rapid development has been the decrease in the supply of natural resources. At the same time there has been an increased realization that there are abundant alternative bioresources. Two factors-economics and versatility-have also stimulated interest in chitosan's utilization in various fields. Chitin and chitosan derivatives have applications in fields that range from fertilizers to pharmaceuticals. Chitosan is no longer just a waste by-product from the seafood processing industry. This material is now being utilized by industry to solve problems and to improve existing products, as well as to create new ones.
Applications of Chitin and Chitosan is illustrated with over 100 photos, charts, graphs and figures and more than 40 tables.
Applications of Chitin and Chitosan will be of interest to industrial personnel involved in bioprocessing as well as bioengineering students, specialists in the biomedical and biopharmaceutical industry, biochemists, food engineers, environmentalists, and microbiologists and biologists who specialize in chitosan technology. Publication: Fall 1996.