This reader offers some of the most important writing to date from the science of COVID-19 and what science says about its spread and social implications. The readings have been carefully selected, introduced, and interpreted for an introductory or graduate student readership by a distinguished medical sociology and political science team. While some of the early science was inaccurate, lacking sufficient data, or otherwise incomplete, the author team has selected the most important and reliable early work for teachers and students in courses on medical sociology, public health, nursing, infectious diseases, epidemiology, anthropology of medicine, sociology of health and illness, social aspects of medicine, comparative health systems, health policy and management, health behaviors, and community health. Global in scope, the book tells the story of what happened and how COVID-19 was dealt with. Much of this material is in clinical journals, normally not considered in the social sciences, which are nonetheless informative and authoritative for student and faculty readers. Their selection and interpretation for students makes this concise reader an essential teaching source about COVID-19. An accompanying online resource on the book's Routledge web page will update and evolve by providing links to new readings as the science develops.

Written by a public health practitioner and a medical historian, Viral Pandemics explores the terrifying world of viruses as the cause of all acute pandemics since 1900, including the COVID-19 pandemic. The book illuminates the critical dual roles of viral biology and increasing global interconnectedness that have resulted in an escalating pandemic spiral. Viral Pandemics is the first book to focus exclusively on pandemics caused by viruses and the first to report the COVID-19 pandemic. In each chapter, the historiographic narrative follows the path of the virus from its original detection through its first appearance as the cause of disease, to its emergence as an explosive pandemic. Scientific information is presented in an accessible, straightforward style in compelling narratives that introduce the extraordinary universe of diverse, opportunistic viruses whose remarkable capacities make them formidable adversaries. The book makes it clear that global viral disease challenges are a persistent reality with the potential to cause catastrophic loss of life and major social and economic damage. A summary chapter draws together lessons learned and develops a proposed multidisciplinary global response. Viral Pandemics is the only book that provides a complete historical narrative focused on viral pandemics. This comprehensive survey is designed for students and scholars in biology, epidemiology, public health, global history and the history of medicine, as well as general readers interested in the science of pandemics.

The Millennium Development Goals, adopted at the UN Millennium Summit in 2000, are the world's targets for dramatically reducing extreme poverty in its many dimensions by 2015?income poverty, hunger, disease, exclusion, lack of infrastructure and shelter while promoting gender equality, education, health and environmental sustainability. These bold goals can be met in all parts of the world if nations follow through on their commitments to work together to meet them. Achieving the Millennium Development Goals offers the prospect of a more secure, just, and prosperous world for all. The UN Millennium Project was commissioned by United Nations Secretary-General Kofi Annan to develop a practical plan of action to meet the Millennium Development Goals. As an independent advisory body directed by Professor Jeffrey D. Sachs, the UN Millennium Project submitted its recommendations to the UN Secretary General in January 2005. The core of the UN Millennium Project's work has been carried out by 10 thematic Task Forces comprising more than 250 experts from around the world, including scientists, development practitioners, parliamentarians, policymakers, and representatives from civil society, UN agencies, the World Bank, the IMF, and the private sector. Coming to Grips with Malaria in the New Millennium presents an innovative strategic framework for relieving the burden that malaria imposes on society through the implementation of tried and tested anti-malarial interventions designed to improve health nationally and to promote economic development locally. Recommendations include early diagnosis, treatment with effective anti-malarial medicines, the use of insecticide treated nets, indoor residual spraying, managing the environment, improving housing, extending health education and improving monitoring and evaluation systems.

The Millennium Development Goals, adopted at the UN Millennium Summit in 2000, are the world's targets for dramatically reducing extreme poverty in its many dimensions by 2015?income poverty, hunger, disease, exclusion, lack of infrastructure and shelter while promoting gender equality, education, health and environmental sustainability. These bold goals can be met in all parts of the world if nations follow through on their commitments to work together to meet them. Achieving the Millennium Development Goals offers the prospect of a more secure, just, and prosperous world for all. The UN Millennium Project was commissioned by United Nations Secretary-General Kofi Annan to develop a practical plan of action to meet the Millennium Development Goals. As an independent advisory body directed by Professor Jeffrey D. Sachs, the UN Millennium Project submitted its recommendations to the UN Secretary General in January 2005. The core of the UN Millennium Project's work has been carried out by 10 thematic Task Forces comprising more than 250 experts from around the world, including scientists, development practitioners, parliamentarians, policymakers, and representatives from civil society, UN agencies, the World Bank, the IMF, and the private sector. This report lays out the recommendations of the UN Millennium Project Task Force 5 Working Group on TB. The Working Group's recommendations include expanding access to DOTS programs, implementing efforts against HIV-related TB and multidrug-resistant (MDR) TB, engaging all primary care providers and communities in high quality TB care, and developing new diagnostics, drugs and vaccines. These bold yet practical approaches will enable countries in every region of the world to halve the prevalence of TB by 2015.

This book offers practical tips and essential guidance for trainees and specialists in clinical microbiology and infectious diseases and healthcare professionals interested in infection management to put theoretical knowledge into daily practice. Using common clinical situations and problems as a guide, the handbook is intended to support the healthcare professional from interpretation of laboratory results to consultation and infection control. Key Features Concisely covers the critical clinical microbiology and infectious disease topics, with an emphasis on translating theoretical knowledge into clinical practice Provides practical guidance and solutions to commonly encountered issues and scenarios Presented in an accessible format to rapidly aid the clinician in day-to-day practice

* Includes many captivating illustrations enabling easy comprehension. * Explains microbiome functions from algae to vertebrates. * Reveals how microbiomes contribute to the health of the hosts and the ecosystems. * Describes the impact of dysbiosis on diseases, food security and climate change. * Boxed sections provide a detailed analysis of concepts and are accompanied by vivid illustrations.

Written by a public health practitioner and a medical historian, Viral Pandemics explores the terrifying world of viruses as the cause of all acute pandemics since 1900, including the COVID-19 pandemic. The book illuminates the critical dual roles of viral biology and increasing global interconnectedness that have resulted in an escalating pandemic spiral. Viral Pandemics is the first book to focus exclusively on pandemics caused by viruses and the first to report the COVID-19 pandemic. In each chapter, the historiographic narrative follows the path of the virus from its original detection through its first appearance as the cause of disease, to its emergence as an explosive pandemic. Scientific information is presented in an accessible, straightforward style in compelling narratives that introduce the extraordinary universe of diverse, opportunistic viruses whose remarkable capacities make them formidable adversaries. The book makes it clear that global viral disease challenges are a persistent reality with the potential to cause catastrophic loss of life and major social and economic damage. A summary chapter draws together lessons learned and develops a proposed multidisciplinary global response. Viral Pandemics is the only book that provides a complete historical narrative focused on viral pandemics. This comprehensive survey is designed for students and scholars in biology, epidemiology, public health, global history and the history of medicine, as well as general readers interested in the science of pandemics.

This book offers practical tips and essential guidance for trainees and specialists in clinical microbiology and infectious diseases and healthcare professionals interested in infection management to put theoretical knowledge into daily practice. Using common clinical situations and problems as a guide, the handbook is intended to support the healthcare professional from interpretation of laboratory results to consultation and infection control. Key Features Concisely covers the critical clinical microbiology and infectious disease topics, with an emphasis on translating theoretical knowledge into clinical practice Provides practical guidance and solutions to commonly encountered issues and scenarios Presented in an accessible format to rapidly aid the clinician in day-to-day practice

Epidemic trend analysis, timeline progression, prediction, and recommendation are critical for initiating effective public health control strategies, and AI and data analytics play an important role in epidemiology, diagnostic, and clinical fronts. The focus of this book is data analytics for COVID-19, which includes an overview of COVID-19 in terms of epidemic/pandemic, data processing and knowledge extraction. Data sources, storage and platforms are discussed along with discussions on data models, their performance, different big data techniques, tools and technologies. This book also addresses the challenges in applying analytics to pandemic scenarios, case studies and control strategies. Aimed at Data Analysts, Epidemiologists and associated researchers, this book: discusses challenges of AI model for big data analytics in pandemic scenarios; explains how different big data analytics techniques can be implemented; provides a set of recommendations to minimize infection rate of COVID-19; summarizes various techniques of data processing and knowledge extraction; enables users to understand big data analytics techniques required for prediction purposes.

Now in its sixth edition, Infectious Diseases in Obstetrics and Gynecology remains the only book to comprehensively cover infectious diseases in both obstetrics and general gynecology. Distilling complex clinical problems into an easy to use format, this text is divided in four unique sections, and some of these topics include:

In 2019 the world was struck with the Coronavirus (COVID-19) infecting major portions of the world's population. There were no vaccines or treatments available to help mitigate the disease or offer a cure. The world's health systems were inundated with massive numbers of patients with varying ranges of symptoms, acuity, and levels of criticality. The world's healthcare organizations soon found themselves in an unmanageable situation, directly impacting the ability to manage patients across the entire healthcare environment. Most healthcare institutions had plans for emergency preparedness and procedures to deal with temporary crises, none of which were effective against the impact of COVID-19. COVID-19 was a highly contagious disease, resulting in high volumes of admissions with long lengths of stay. The virus quickly overwhelmed institutions with large patient volumes, resulting in shortages of patient beds, medical equipment, personal protective devices, cleaning agents, and other critical supplies. Hospital operations were further impacted by staff shortages due to exposure, resulting contagion, the shutdown of transit systems, and responsibilities at home due to school and business closures. This timely and important book describes the impact on the hospital ability to provide patient care and how healthcare institutions leveraged diverse technology solutions to combat the impact of COVID-19 on providing patient care. The authors also discuss implementation of these technology solutions and the many lessons learned of how healthcare institutions can enhance their emergency preparedness in the future from the COVID experience. The authors would like to acknowledge, thank, and dedicate this book to the hundreds of thousands of healthcare workers around the world who spent countless hours and put their own lives and families lives at risk to help patients though this pandemic.

Over the past decades, infectious disease epidemics have come to increasingly pose major global health challenges to humanity. The Anthropology of Epidemics approaches epidemics as total social phenomena: processes and events which encompass and exercise a transformational impact on social life whilst at the same time functioning as catalysts of shifts and ruptures as regards human/non-human relations. Bearing a particular mark on subject areas and questions which have recently come to shape developments in anthropological thinking, the volume brings epidemics to the forefront of anthropological debate, as an exemplary arena for social scientific study and analysis.

This book focuses on the era during which the cause of tuberculosis had been identified, and public health officials were seeking to prevent it, but scientists had not yet found a cure. By examining tuberculosis comparatively in two Atlantic port cities, Buenos Aires and Philadelphia, it explores the medical, political and economic settings in which patients, physicians and urban officials lived and worked. Reber discusses the causes of tuberculosis, treatments and public health efforts to stop contagion, and how factors such as gender, age, class, nationality, beliefs and previous experiences shaped patient responses, and often defined the type of treatment.

The discovery of Toll-like receptors (TLRs) in the late 1990s ushered in a new age of discovery for innate immunity. The importance of TLRs for immunology and biomedical research was recognized with the Nobel Prize for Medicine or Physiology in 2011. The prize was shared by three scientists: Ralph Steinman (for the discovery of dendritic cells, which express TLRs and whose activation by them provides a link between innate and adaptive immunity), Jules Hoffman (who made the pioneering observation of Toll in fruit fly anti-fungal immunity) and Bruce Beutler (who uncovered the role of TLR4 in the response to LPS). Work on TLRs inspired many researchers, and led to a search for other receptors in innate immunity. There are now several additional families of such receptors known, notably RIG-I-like receptors (RLRs), C-type lectin receptors (CLRs) and AIM2-like receptors (ALRs). A notable feature is the detection of nucleic acids from pathogens, but also from host cells in certain contexts, particularly in autoimmune diseases. Nucleic Acid Sensors and Antiviral Immunity presents a timely and extensive account of the detection of nucleic acids in infection and inflammation. We have chapters by Beutler, Hoffman and Shizuo Akira, who is the most cited immunologist of the past ten years, for his work on innate immunity, which gives us an indication of the importance of the field. Several other pioneers in the field present comprehensive and highly lucid up-to-date accounts of their particular interests, revealing the large amount of activity in the past few years, as the literature continues to grow and become ever more complex. The fly yet again provides new insights, and anti-viral mechanisms in this key model organism are described. Other topics include the ability of viruses such as poxviruses, hepatitis C virus and HIV to interfere with detection and signalling; new insights into signalling including subcellular localization of signalling proteins, complex regulation o

This collection of essays will stimulate the use of ionophores in different research areas. It includes information on potential breakthroughs in the halogenated derivatives of lasalocid and ethers of antibiotic A204A, polyethers and analytical techniques used to unravel their complex structures.

An invaluable resource, this book covers the full range of respiratory infections and explores the techniques used to detect the pathogens involved in asthma. Fifteen international experts representing the range of specialties involved in treating asthma examine the relationship between asthma and infection. They provide authoritative, time-tested guidance clinicians and researchers can utilize and trust. They cover bacterial and viral respiratory infections and pathogen detection, examining how microbes, infections, and antibiotic and anti-inflammatory agents affect asthma. The book helps readers identify the basic, translational, clinical aspects of asthma bacterial infection, inflammation, and allergic response. Not only does it present the facts but raises questions that will stimulate the clinical and research communities to explore new avenues that may provide clear answers to old questions.

Analyzing a key cause of infectious morbidity in immunosuppressed and immunocompromised patients, this source spans the most recent strategies to improve and expedite the diagnosis, identification, and treatment of fungal infections. With authoritative contributions from experienced clinicians in the field, this reference tracks developments in imaging, susceptibility testing, and strain typing to combat these conditions in transplant, surgical, oncology, and intensive care units.

In the care of pediatric patients, infectious diseases comprise over 50% of the clinical diagnoses. For this reason, it is essential to have a basic understanding of infectious processes and to keep abreast of new developments in the field. This reference stands as a convenient and time-saving reference for clinicians on the diagnosis, treatment, and prevention of pediatric infections diseases and is completely updated to include the latest guidelines from esteemed societies such as the Infectious Disease Society of America, the Centers for Disease Control and Prevention, the American Thoracic Society, and the American Academy of Pediatrics.

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging agents currently in development. Written by experienced professionals in the field, this guide uses an abundance of examples to depict methods to apply pharmacodynamic concepts to everyday clinical practice.

Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy --brought prion-related diseases international attention. Exceptionally dramatic, these diseases progressively and inexorably destroy the cognitive, motor, and sensorial skills that are the essence of human beings. Prions: The New Biology of Proteins provides a well-organized overview of what is known about prion-related diseases. This comprehensive work reviews the symptoms, epidemiology, and neuropathology of the disease. It focuses on evidence supporting the idea that TSEs result from a novel disease mechanism: transmission by replication of the misfolding of a single protein in the absence of nucleic acids. Following this hypothesis, the book examines the structure, conversion, and mechanism of prion propagation and details its cellular biology. It explores the transmission, discusses the challenges involved with diagnosis, and considers various therapeutic avenues that are presently being explored. A cohesive volume that integrates the pioneering work of many researchers, this book is authored by Claudio Soto, an internationally renowned researcher whose innovative work has led to an increased understanding of the heretical biology of prions and the development of novel strategies for treating and diagnosing neurodegenerative diseases. As protein misfolding diseases are his specialty, Soto also looks at the phenomenon from a wider perspective. He examines other diseases that display folding aberrations, considers how commonly such aberrations occur in nature, and asks readers to open their minds to consider the impact of prions on broader areas of biology, public health, and biotechnological

Over the last two decades, attempts to control the problem of tuberculosis have become increasingly more complex, as countries adopt and adapt to evolving global TB strategies. Significant funding has also increased apace, diagnostic possibilities have evolved, and greater attention is being paid to developing broader health systems. Against this background, this book examines tuberculosis control through an anthropological lens. Drawing on ethnographic case studies from China, India, Nepal, South Africa, Romania, Brazil, Ghana and France, the volume considers: the relationship between global and national policies and their unintended effects; the emergence and impact of introducing new diagnostics; the reliance on and use of statistical numbers for representing tuberculosis, and the politics of this; the impact of the disease on health workers, as well as patients; the rise of drug-resistant forms; and issues of attempted control. Together, the examples showcase the value of an anthropological understanding to demonstrate the broader bio-political and social dimensions of tuberculosis and attempts to deal with it.

Outlining the best means of infection management and emphasizing early recognition and identification of pathogens, this trailblazing volume pinpoints the distinct immunodeficiencies related to specific malignancies that result in predictable opportunistic infections-containing accessible reviews of the latest scientific research, reports from the forefront of clinical practice, and copious illustrations and tables to be of maximal benefit to the reader.

Living through the Covid-19 global pandemic has changed the way that we experience our lives, the way that we relate to one-another, and the way that we engage with the world. Focusing contextually on the initial lockdowns of the pandemic in 2020, this book proposes that art-based research has a central, illuminative role to play in our understanding of unfolding crises. The changes brought on by the global event may not be readily accessible or expressible through traditional academic research. Art-based research offers the opportunity to explore, document, and reflect on the emerging and often ineffable qualities of transformed lives by drawing on emotional, bodily, and interactive aspects of experience. Such an approach allows for meaning-making that makes room for reflexive, interpersonal, and dialogical engagement. The contributions aim to capture and explore lived experiences of the pandemic, as well as begin a discussion about how meaning-making is changing through and beyond the pandemic. This book further explores how the nature and practice of art-based research in itself has been challenged and transformed. The book will be of interest to scholars working in art education, art psychotherapy, consumer research, visual studies, cultural studies, and sociology.

Understand, manage, and treat Long Covid. Reports suggest that over 100m people around the world are living with Long Covid (more than 1.5m in the UK) yet reliable, clear information and guidance remains scarce. This book is the definitive guide to understanding, managing and treating the condition. Written by the world's leading immunologist Professor Danny Altmann and expert patient Gez Medinger, The Long Covid Handbook translates cutting-edge science, patient-led research and practical guidance with clarity. This book will equip you with expert information and advice on: - Long Covid's 200 symptoms, which include fatigue, brain fog, breathlessness and more - Tips for recovery - Which treatments are most effective and why - Who is most susceptible to the condition and why - What we can learn about Long Covid from other chronic illnesses - The impact on mental health This is the essential guide for anyone living with the condition, as well as clinicians seeking to better understand this little-understood illness.