A NEW EYE-OPENING ILLUSTRATED EDITION OF MEERA SENTHILINGAM'S TIMELY GUIDE For decades scientists have been warning of a global pandemic, and the Covid-19 coronavirus outbreak has realised their worst fears. Covid-19 and monkeypox make Outbreaks & Pandemics an essential guide to the future. It narrates a disquieting journey through the history, science, and politics of humankind's ongoing war against contagion; investigates modern responses; and assesses the chances of eradicating disease in the future. it also reveals how globalisation, mobile populations, climate change, vaccine hesitancy, and drug-resistant pathogens have combined to create the perfect conditions for pandemics to spread. This updated and illustrated edition is essential reading, combining extensive research with illuminating photographs and infographics to chart the pattern of outbreaks and reveal the microscopic world at their heart.

La placca ateromasica rappresenta l'elemento patogenetico principale di numerosi processi patologici a carico degli apparati cardiovascolare, cerebrovascolare e nefrovascolare. Al fine di prevenire e trattare tali patologie, che rappresentano, per frequenza nella popolazione generale, le principali cause di morte e disabilita nel mondo occidentale, appare necessaria la conoscenza dei principali meccanismi patogenetici alla base dello sviluppo della placca aterosclerotica. In questo volume viene presentata una sintesi aggiornata delle tematiche relative all'eziopatogenesi, alla prevenzione e al trattamento dell'aterosclerosi, dedicando ampio spazio al recente concetto di aterosclerosi come malattia infiammatoria e agli ultimi studi volti ad individuare una possibile eziopatogenesi infettiva del processo. Il testo, rivolto principalmente ai medici di Medicina Generale e agli studenti delle lauree sanitarie, vuole offrire una panoramica sulle attuali conoscenze e sulle nuove teorie formulate in questi ultimi anni. Quest'opera rappresenta pertanto uno strumento di rapido aggiornamento con spunti interessanti per eventuali approfondimenti."

Breast pathology is arguably considered the most challenging and controversial area of diagnostic pathology. Many gradations of normal, pre-cancerous, and cancerous conditions are often indistinguishable, making a clear-cut diagnosis very difficult and often a cause for intense debate. This latest book in the Cambridge Illustrated Surgical Pathology series comprehensively covers all methods utilized by pathologists to accurately diagnose diseases affecting the breast. Malignant tumors are the predominant focus, but a full spectrum of inflammatory disorders and hyperplasias is also covered in detail, and the book uniquely shows the progression of disease states from incipient to advanced. Findings are diagnosed not only through the light microscope but also through genetic, molecular, and immunologic modalities; the text additionally includes the interpretation of cytologic specimens as an important diagnostic modality in breast pathology. The book is highly illustrated, with more than 300 color photomicrographs, and accompanied by a CD-ROM of all images in downloadable format.

Die Osteologie ist als interdisziplinares Fach in den letzten Jahren verstarkt in den Blickpunkt geruckt. Mehr als 1800 Facharzte in Deutschland sind inzwischen zertifizierte Osteologen DVO. Fur diese und alle zukunftigen Osteologen wurde die Reihe praxisnaher Kurs- und Fortbildungsbucher konzipiert. Sie beruht auf den Inhalten der regelmassig stattfindenden osteologischen Seminare der Sektion Osteologie der Deutschen Gesellschaft Orthopadie/Orthopadische Chirurgie (DGOOC) und begleitet den Zertifizierungskurs.

This atlas describes the histologic changes relevant to the modern practice of forensic pathology. It guides the reader through the common questions that the forensic pathologist will need to answer in relation to the cause of death, such as: is this feature artifact or is this real? What does this signify? How old is this injury? The book focuses on key issues of forensic importance - e.g. sudden death, environmental deaths, injury timing and suspected child abuse. The book is highly illustrated with color photographs to increase the understanding of changes related to disease, decomposition and artifact. All illustrations are also available on a CD-ROM packaged with the print book. Ideal as a source of quick reference next to the microscope, this is essential reading for forensic pathologists, forensic pathology fellows, pathologists who consult in forensic cases, pathology residents, autopsy pathologists, coroners and forensic investigators.

Written in response to reader requests for a short, "to the point" text that clearly summarizes the most important chemical elements of therapeutically relevant drug classes, Essentials of Foye's Principles of Medicinal Chemistry is a concise, quick-reference source of reliable information in the field. Derived from the highly regarded Foye's Principles of Medicinal Chemistry , this focused text provides an essential understanding of drug action and demonstrates its practical application to today's pharmacy practice. Highlights the "take home" chemical points of every chapter in the parent text, and uses an easy-to-read, bulleted format to convey essential concepts. Covers mechanism of action (MOA), structure-activity relationships (SAR), physicochemical and pharmacokinetic properties, metabolism, and clinical applications in all chapters. Uses numerous figures and tables to illustrate key concepts and make reference quick and easy. Summarizes additional information such as adverse effects, drug-drug or drug-food interactions, chemical points of interest, and unique aspects of clinical use in side boxes or Chemical Note side bars. Concludes each chapter with a section emphasizing the clinical relevance of chapter content, as well as review questions for self-assessment. Written by the same international team of renowned researchers and academicians as Foye's Principles of Medicinal Chemistry Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use

Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 3500 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.

In this issue of Surgical Pathology Clinics, guest editor Dr. Aatur D. Singhi brings his considerable expertise to the topic of Pancreatobiliary Neoplastic Pathology. Top experts in the field discuss precursor and malignant neoplasms (with mimics) such as molecular discoveries (e.g., IOPNs), neoadjuvant treatment histopathology (e.g., grading), immunohistochemical biomarkers (e.g., prognostic markers for neuroendocrine tumors), and more. Contains 13 relevant, practice-oriented topics including the diagnostic challenge of evaluating small biopsies from the pancreatobiliary system; integrating molecular analysis to the pathologic evaluation of pancreatic cysts; the cytomorphologic and molecular assessment of bile duct brushing specimens; advances in the surgical approach to pancreatobiliary neoplasms; and more. Provides in-depth clinical reviews on pancreatobiliary neoplastic pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This book is prepared for patients who suffer from 'Burning mouth disease', also referred to as 'Burning mouth syndrome'. It gives a comprehensive overview of the disease, its symptoms and management. Readers will learn about the terminology and definition of 'Burning mouth disease', and its suggested causes. Attention is paid to symptoms of various diseases that may mimic those of burning mouth disease. Neurological and psychogenic aspects are well covered, as are the many reported pharmacological and non-pharmacological treatment modalities. The combined training of the author in oral surgery, oral pathology and oral medicine has provided him with exceptional expertise in both the diagnosis and the management of patients with burning mouth disease. This book is a must have for everyone who is interested in this enigmatic disease.

A growing body of literature indicates that diseases can affect women and men differently. As sex differences extend far beyond biology, it is crucial to adopt a bicultural approach towards understanding human disease patterns and processes. This 1998 book synthesizes modern medical research with paleopathological investigations. Conditions such as osteoporosis and osteopenia, iron deficiency anaemia, infection and immune reactivity and trauma are explored. Recognizing the relationship between these conditions and aspects of sex and gender in past populations assists in the formulation of models from which modern disease processes can be better understood. Exploring the differences will provide provocative ideas for all those in physical anthropology, archaeology, evolutionary biology, history of medicine and women's studies interested in how sex and gender impacts on disease.

Questo volume si prefigge di fornire a tutti coloro che, di fronte ad un sospetto clinico di Pneumopatia Infiltrativa Diffusa, si sentono confusi stante la molteplicita delle patologie in gioco a fronte di una sintomatologia, di un radiogramma del torace e di reperti funzionali sovente aspecifici. Nella pratica clinica, l'iniziale orientamento in questo labirinto e sempre dato sempre piu spesso dalla Tomografia Computerizzata ad Alta Risoluzione (HRTC) i cui reperti consentono di formulare le prime ipotesi e di programmare gli accertamenti successivi ma talvolta sono di per se stessi conclusivi. La proposta degli Autori e di usare proprio l'HRTC come "filo d'Arianna" per districarsi nel dedalo di queste pneumopatie, e precisamente di partire dalla TC del Paziente, identificarne il pattern predominante per mezzo di immagini di riferimento e poi, con l'aiuto di tavole sinottiche, di restringere il ventaglio delle ipotesi diagnostiche ad una o comunque ad un numero limitato di malattie. Ciascuna malattia e poi trattata in uno spazio dedicato dove vengono descritti l'epidemiologia ed i fattori di rischio, le modalita di presentazione e i dati funzionali e successivamente vengono illustrati gli aspetti anatomopatologici, radiologici ed i reperti del lavaggio broncoalveolare. Non mancano paragrafi che ne delineano evoluzione e complicanze ed altri che propongono concretamente l'iter diagnostico piu opportuno per giungere alla diagnosi definitiva."

Das Pathologische Museum gehorte mit seinen uber 20.000 von Rudolf Virchow zusammengetragenen Objekten zu den umfangreichsten und bedeutendsten der Welt. Als Teil der Berliner Universitat diente es dem Unterricht und der Forschung, die Halfte des Hauses war als Schausammlung fur die Offentlichkeit zuganglich. Die Frage, was ein Museum, die Musealisierung einer Wissenschaft, im 19. Jahrhundert fur einen Forscher und sein Fach bedeuten und welche Funktionen dieser Institution zugedacht werden konnten, steht im Zentrum dieses kulturgeschichtlichen Annaherungsversuches an Virchows Pathologisches Museum. Diese Geschichte des Pathologischen Museums handelt vor allem vom ambivalenten Status von Sammlungsobjekten zwischen Aufklarung und Sakralisierung, Wissenschaft und Kunst, Fortschrittsglauben und Vergangenheitssicherung."

This new publication takes a critical, evidence-based look at the efficacy of new diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of new products being brought out by the pharmaceutical industry. However, in many cases the evidence which supports the use of these new methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide an invaluable overview of the diverse applications of biomarkers in medicine.

Die hAufigste pathologische WandverAnderung des Dickdarms ist die Divertikulose. WAhrend die PrAvalenz der Divertikelerkrankung zu Beginn des 20. Jahrhunderts noch bei 5% lag, betrAgt sie heute mehr als 50%. Dementsprechend stellt die Divertikulitis in praktisch jedem Krankenhaus einen relevanten Anteil der zu behandelnden Patienten dar. Die zum Teil umwAlzenden Neuerungen und Weiterentwicklungen in Diagnose und Therapie der Divertikulitis erfordern, den gegenwArtigen Kenntnisstand umfassend zu definieren und im Sinne der "evidence-based" Medizin klare Empfehlungen zum Arztlichen Vorgehen zu formulieren. Den Rahmen hierfA1/4r bildete ein Symposium in Aachen unter Beteiligung renommierter nationaler und internationaler Referenten aus den Bereichen Pathologie, Gastroenterologie und Chirurgie.

Primarilly designed for medical students and junior doctors in clinical practice, this should also be a useful reference to postgraduate students in chemical pathology (clinical biochemistry), laboratory scientists, pathologists and medical laboratory technologists. Covering the field of chemical pathology, the biochemical basis of disease, it provides a basic understanding of the relationship between abnormal biochemical test results and disease states. A rational approach to proper selection and interpretation of biochemical investigations is adopted for each organ system or analyte. Emphasis is placed upon areas and problems most commonly met in clinical practice. Material is presented in a clear, condensed format to aid the study process, and the text is supplemented with illustrations.

Frozen section of Neuropathology-related cases is performed while the patient is undergoing surgery. Intraoperative consultation is used to help guide intraoperative management of the case and to ensure that adequate and appropriate tissue has been obtained for purposes of making an accurate final diagnosis. Frozen section diagnosis is often a highly demanding situation for the pathologist, who must render a diagnosis quickly and provide sound guidance and advice. In addition to the need for rapid recall of differential diagnoses, there are many pitfalls and artifacts that add to the risk of frozen section diagnosis that are not present with permanent sections of fully processed tissue that can be examined in a more leisurely fashion. Most standard pathology textbooks focus primarily on permanent section material and largely ignore the topic of frozen section. The purpose of this volume is to add to the Frozen Section Library series and provide a convenient, user friendly handbook to assist in the evaluation of central nervous system related frozen sections. It provides a useful reference, organized around differential diagnoses, primarily by location in the central nervous system. The text will be illustrated with color pictures and include tables as appropriate. This text provides a valuable tool for the practicing surgical pathologist both in community and in academic centers as well as pathology residents and fellows in training when confronted with Neuropathology frozen section.

Gerade im Alter kommt es vor, dass man vergesslicher wird und sich Wichtiges oft nicht mehr merken kann. Geistige Fitness kann aber von Jung und Alt gemeinsam geubt und verbessert werden. Das gilt fur gesunde Menschen genauso wie fur Personen, die an Alzheimer oder einer anderen Demenzerkrankung leiden. Das Trainingsbuch "Nimm dir Zeit fur Oma und Opa" enthalt Gedachtnisubungen in allen Schwierigkeitsstufen fur altere Menschen und ihre Angehoerigen. Durch kurze tagliche UEbungseinheiten werden die Gedachtnisleistung, Konzentration und Aufmerksamkeitsfahigkeit gefoerdert. Wortflussigkeit und Allgemeinwissen werden trainiert. Die UEbungen sind auch fur bereits an Alzheimer erkrankte Personen geeignet. Die Autoren Croy und Gatterer sind Psychotherapeuten. Sie haben ihre beruflichen und privaten Erfahrungen mit kognitiven Trainings fur altere Menschen in diesem Buch verarbeitet.

Die Neuroonkologie hat sich in den vergangenen Jahren als eine eigene Disziplin sowohl innerhalb der Neurologie als auch interdisziplinar etabliert: ubergreifend fur Onkologie, Interne Medizin mit onkologischen Patienten, Neurochirurgie, Radiochirurgie und theoretische Facher. Eine rasche Weiterentwicklung erfolgt sowohl in der Diagnostik als auch beim Therapieangebot. Das Buch ist nach pathophysiologischen Gesichtspunkten aufgebaut. Dies ermoeglicht den AErzten eine rasche Identifikation der wahrscheinlichsten Ursache der Stoerung und zugleich eine ausfuhrliche Differentialdiagnose. Damit ist die "Praktische Neuroonkologie" ein unentbehrlicher Ratgeber in der taglichen Arbeit fur Neurologen, Onkologen und alle AErzte, die Patienten mit neuroonkologischen Problemen behandeln. Die Auflistung aller wichtigen in der Neuroonkologie verwendeten Skalen und Instrumente zur Erfassung der Lebensqualitat garantiert den praktischen Nutzen dieses Kompendiums.

Cytologic examination of the cerebrospinal fluid is a technically simple, yet productive, diagnostic procedure. Here is a practical guide to this method, as used in the diagnosis of different pathologies. High-quality slides depict the common cerebrospinal fluid cell types, cell anomalies in inflammatory conditions and neoplastic and non-neoplastic disorders, and cases with contaminants. It 's required reading for pathologists, as well as neurologists and neurosurgeons.

A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease. Key features: * New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment * Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers * Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials * Photomicrographs present normal and abnormal blood cells from a variety of hematological conditions along with descriptive text

Das vorliegende Werk ist das Ergebnis umfangreicher vergleichender Untersuchungen an Wirbelsaulenpraparaten im Rahmen eines Schwerpunktes der Weichteil- und Knochenpathologie an den Berufsgenossenschaftlichen Kliniken Bergmannsheil Bochum. Schwerpunkte des Buches sind:
- Wertigkeit und Aussage moderner bildgebender Verfahren, besonders der Computertomographie zur Diagnose und Differentialdiagnose degenerativer Veranderungen des Achsenskelettes.
- Darstellung der rontgenographischen Befunde unter Berucksichtigung von Standard-Verfahren bis zur 3D-Rekonstruktion in der Computertomographie.
- Detaillierte Korrelation zu makroskopischen und mikroskopischen morphologischen Befunden der degenerativen Wirbelsaulenveranderungen mit besondererBerucksichtigung der kleinen Wirbelgelenke."