Get complete massage pathology information in one convenient text! Mosby's Pathology for Massage Professionals, 5th Edition provides concise pathology information, along with specific therapeutic recommendations. Coverage of more than 300 pathologies shows you how to appropriately tailor treatment, and more than 500 full-color photographs make it easier to recognize common pathologies. Written by massage therapy educator, researcher, and practitioner Dr. Susan Salvo, this resource provides the pathology knowledge you need to succeed in the classroom and in your career. Coverage of more than 300 pathologies provides students with ample information without being overwhelming. More than 500 full-color photographs help students recognize common diseases and conditions. Case studies in each chapter encourage students to apply their knowledge and develop clinical reasoning skills. UNIQUE! Hospital-Based Massage chapter covers different protocols needed for massage therapists working in institutionalized care settings and provides useful information about working with clients who are medically fragile or in hospice care. User-friendly, comprehensive format makes it easy to find key information with learning objectives, a systems overview that includes the aging process, and pathologies that feature descriptions, etiologies, signs and symptoms, current treatment measures including medications in bold-italics for easy identification, and massage modifications. UPDATED! Refreshed artwork throughout the book visually reinforces key concepts and techniques. UPDATED! Information on the biopsychosocial model, transmission-based precautions, and disinfection procedures for today's massage practice. UPDATED! Inclusion of sleep disorders, opioids, and CBD use by clients, and their massage considerations. UPDATED! Addition of evidence-based protocols for scar tissue, constipation, hypoglycemia, and more. UPDATED! Detailed information on how to work with clients after surgery, who have a colostomy, amputations, or who are on dialysis. UPDATED! Thoroughly reviewed and revised pathologies feature current research findings and reflect what students will encounter in today's massage therapy practice, with a focus on evidence-informed practice.

Combining theory and practice, this book is a comprehensive analysis of suffocation, asphyxiation, and neck pressure deaths. It includes important developments in the field such as lung histomorphology in fatal strangulation, systematic dissection of the larynx, biochemical findings, and postmortem imaging. Significant challenges arise in accurately diagnosing these deaths when compared to other forms of external violence. International experts explain the pitfalls and subtleties of identifying such cases making this an important resource for readers involved in such investigations. Tables, statistics, scientific and historical evidence throughout further validate the value of this book. Provides a comprehensive introduction to every major topic of asphyxia and neck pressure death Features more than 300 figures to aid understanding and facilitate accurate diagnosis of these death types Includes the important topic of postmortem radiology findings Navigates the reader through the potential pitfalls and misdiagnoses of asphyxia and neck pressure deaths with expert guidance About the Editor Professor Burkhard Madea MD, Director, Instiute of Forensic Medicine, University of Bonn, Germany, is a world-renowned forensic pathologist and the author of more than a dozen books and 600 papers.

Sudden cardiac death represents a highly heterogeneous group of cardiovascular disorders. While some may initially think of sudden death as primarily an arrhythmogenic event, this actually represents the minority of cases of sudden cardiac death. In the vast majority of cases, there is an underlying anatomic disorder of the cardiovascular system responsible for the ultimate hemodynamic collapse known as sudden cardiac death. This book will provide an atlas type review of ischemic and non-ischemic etiologies of sudden cardiac death. Beyond the atlas, however, will be a "clinical pathologic correlation" for each described disorder providing practicing clinicians with practical information to facilitate proper diagnosis and treatment. While an increasing array of noninvasive diagnostic tools continue to develop, the sad fact remains that many of the physicians and operators of these new diagnostic modalities have never actually seen specimens which demonstrate the fundamental pathologic abnormalities. This ability to see first hand the underlying pathology creates an opportunity to advance the science and enhance ones understanding of these disease processes. There is not a comprehensive text on this subject on the market today which provides clinical and patholigical material in such a comprehensive manner.

Rapid evolution of technical advances in infrared sensor technology, image processing, "smart" algorithms, databases, and system integration paves the way for new methods of research and use in medical infrared imaging. These breakthroughs permit easy-to-use, high-sensitivity imaging that can address key issues of diagnostic specificity and engender a new level of diagnostic standardization, thus enabling the even wider use of infrared imaging as a viable, non-invasive, lower-cost, safe and accessible first-line detection modality. Edited by the inventor of the MedATR concept that leads to the first IR-CAD for the early detection of breast cancer, Medical Infrared Imaging presents many of the new ideas, concepts, and technologies that are key to the wider acceptance of infrared imaging as a revolutionary new standard. Beginning with the worldwide advances and their medical applications from a historical perspective, the book provides detailed and comprehensive information on the technology and hardware resulting from these innovative breakthroughs that will make currently contributory infrared information even more pertinent. The book covers the physics and physiological basis of thermal imaging, and such cutting-edge concepts as: dynamic thermal imaging, thermal tomography, the important role of infrared in a multi-modality imaging setting, and novel processing techniques for the early detection of breast cancer. A significant portion of the book introduces new applications such as biometric facial recognition and the clinical use and quantification of the TAU technique which uses functional imaging to determine the relevance, the stage, and the progression of diseases. Effective and reproducible results are crucial and the book emphasizes the importance of standardization, calibration, and protocols. Finally, the editor includes chapters on the use of databases for storage and retrieval of images and the ethical obligations of infrared research and clinical practice. As a comprehensive state-of-the-science and indication of future directions, Medical Infrared Imaging provides the medical and biomedical engineering communities with the tools to fully utilize and further advance the applications of infrared imaging.

This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use. A full-color, 4-page insert shows realistic images of the output for many molecular tests. Learning Objectives open each chapter with an overview of what you should achieve. Key Words are listed and defined at the beginning of each chapter, and are bolded in the text. Review Questions at the end of every chapter let you measure your comprehension. Advanced Concepts are included, but set apart from the rest of the text, for students who want a higher level of learning. Ethics boxes address ethical issues, allowing you to apply your knowledge to real-life scenarios. A glossary of all key words may be easily accessed in the back of the book.

Biopsy Pathology in Colorectal Disease shows how the practising pathologist can extract the maximum of diagnostic value from biopsies of the colon, rectum, and anus. With the advances in colonoscopic mucosal biopsy techniques these are amongst the most frequently encountered specimens in hospital histopathology departments. This new edition provides practising pathologists and those in allied disciplines with a thorough guide to the diagnosis of colorectal conditions, both common and rare, and offers expert guidance in the handling of biopsy specimens. The most valuable information for diagnositc interpretation of the variuos types of inflammatory disease is presented clearly and succinctly, minimizing the use of non-diagnostic terms such as 'non-specific colitis.' Optimal ways of handling and examining polyps, the assessment of biopsies in motility disorders and the interpretation of biopsies of anal lesions are described. A rationale classification and practical approach to dysplasia is presented. The early chapters describe how to recognize the many different features, both normal and abnormal, which can be regarded as signposts to diagnosis. The significance of these diagnostic signposts is briefly described and cross referenced to later chapters, in which the histological features of the specific diseases are covered in greater depth.

Selecting illustrative examples from the recent literature, this reference studies the underlying principles and physics of a wide range of spectroscopic techniques utilized in the pharmaceutical sciences and demonstrates various applications for each method analyzed in the text-showing how knowledge of the mechanisms of spectroscopic phenomena may facilitate more advanced technologies in the field.

Tissue stem cells and their medical applications have become a major focus of research over the past decade. With 16 full-color illustrations, this reference provides a thorough and up-to-date overview of the current and emerging technologies for stem cell research and transplantation. Divided into three sections covering general issues, adult stem cells within specific tissues, and clinical applications, this source studies advances in bone marrow transplantation, cancer development modeling, tumor analysis, and gene therapy.

Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule. Key Features: Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule Documents the adverse effects of antipsychotics on dopamine functions Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems Provides updates on receptor oligomerization and signaling Examines the role of dopamine in tumorigenesis Related Titles Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4) Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0) Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic dermatopathology, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Neoplastic Dermatopathology is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Covers the broad array of cutaneous neoplasms and their differential diagnoses in a concise, practical, and richly illustrated format Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls Features thorough updates throughout, including new information from molecular pathology studies that describe multiple mutations in different cutaneous tumors, and updated staging details for melanoma, cutaneous lymphoma, and other tumors Addresses recent advances in molecular pathology-new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as updated reportable staging details for several new diagnoses and identification of newly recognized tumors Details the expanded scope of knowledge available from the 2018 update to the World Health Organization and European Organization for Research and Treatment of Cancer (WHO-EORTC) Includes more than 2,900 carefully annotated photographs, images, and illustrations plus nearly 1,000 additional digital-only images to help practicing and in-training pathologists reach a confident diagnosis Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Provides essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, paraganglia, pancreas, skin, neuroendocrine neoplasms, and inherited tumor syndromes-more than 150 diagnoses in all Offers a wealth of new information based on recently recognized and discovered endocrine diseases, as well as tumor types with important implications for patient care Includes new content on thyroid lesions and tumors now associated with DICER1 gene mutations; the correlation of newly characterized genetic abnormalities in endocrine tumors associated with responses to targeted therapies; and newly recognized syndromes, such as multiple endocrine neoplasia type 4 and type 5, glucagon cell hyperplasia and neoplasia, and others Meticulously edited by Dr. Vania Nose with contributions from renowned pathologists to ensure that common/classic endocrine diagnoses as well as newly recognized diseases and unusual cases, are well covered Features nearly 2,200 high-quality images in print and online, including clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis Includes updated criteria, terminology, and classifications for a wide range of tumors according to the latest literature, including the 2022 WHO Endocrine and Neuroendocrine Tumors classification Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

Laboratory automation is an increasingly important part of the job description of many laboratory scientists. Although many laboratory scientists understand the methods and principles involved in automation, most lack the necessary engineering and programming skills needed to successfully automate or interface equipment in the lab. A step-by-step, how-to reference and guide, Practical Pharmaceutical Laboratory Automation explores the processes needed to automate the majority of tasks required in research today. The author discusses topics ranging from automated mathematical analysis to robotic automation of chemical processes, to combinations of these and other processes. He presents a detailed discussion of high throughput screening and assay development and takes an in-depth look at Visual Basic as the primary programming language used in laboratories. The text has a dedicated web site (http://www.pharmalabauto.com) that contains all the sample code and examples contained within the text as well as other information related to laboratory automation. Providing a starting point for tackling automation problems, Practical Pharmaceutical Laboratory Automation helps you develop a strategy for automation that gets consistent results.

Presenting all the information your students need in an accessible layout, Essentials of Pathophysiology for Pharmacy will give students a practical understanding of the pathophysiologic basis of selected diseases while providing a rationale for subsequent drug therapy.

Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training-both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports. Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition Features nearly 1,700 annotated images throughout, including neuroimaging studies, histology and immunohistochemical stains, and high-quality medical illustrations Incorporates time-saving features such as a templated, highly formatted design; concise, bulleted text; a variety of test data tables; key facts in each chapter; and an extensive index Includes the enhanced eBook version, which allows you to access all text, figures, and references on a variety of devices

Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key Features Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseases Explores a wide variety of diseases caused by dysfunctional mitochondria.

Biotin and Other Interferences in Immunoassays: A Concise Guide is aimed at clinical laboratory scientists, medical technologists and pathologists who are often the first individuals contacted by a clinician when a laboratory test result does not correlate with clinical presentation. Research scientists working in diagnostics companies will also find this information essential. Sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratory are also discussed so readers can get all important information from one concise guide. This succinct, user-friendly reference provides the necessary information to address high levels of biotin in clinical laboratory results.

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research. Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from nearly 40 international specialists in diverse fields, The Blood-Brain Barrier and Drug Delivery to the CNS -assesses the properties of the blood-brain barrier to determine and measure drug permeability in animals and humans -presents techniques to predict successful drug uptake through in vitro systems or by computation of physicochemical parameters -examines the multidrug resistance protein P-glycoprotein as a natural transporter -analyzes current drug designs to known requirements for transport -looks at drug delivery systems for the brain -and much more! Densely packed with over 800 literature references, drawings, photographs, x-rays, tables, and equations, The Blood-Brain Barrier and Drug Delivery to the CNS is a vital addition to the bookshelves of biochemists, pharmacists, clinical and research pharmacologists, neuroscientists and neurologists, and graduate and medical school students in these disciplines.

The screech of rubber against asphalt. And then the crash: a violent two-car collision resulting in a twisted mass of metal, plastic, and glass-and worse, the deaths of both drivers.

Accident reconstruction is but one phase of road traffic fatality (RTF) cases. Even as police officers draw their last diagram, interview their last witness, and reconstruct their final scenario, a different team of investigators works diligently on solving another puzzle: determining how the victims actually died.

Investigation of Road Traffic Fatalities: An Atlas covers the issues that face medical examiners and coroners in determining the nature and extent of RTF injuries as well as the cause, manner, and circumstances of death. Also ideal for medicolegal death investigators and law enforcement personnel who work with medical examiners and coroners during RTF investigations, this Atlas covers everything from "Typical road traffic fatality injuries" to "Injuries caused by safety/restraint devices" and "Autopsy and toxicology testing."

For anyone involved in RTF probes, Investigation of Road Traffic Fatalities: An Atlas is essential reading.

This is the first critical edition and translation of the first Islamic medical work on fevers. Zad almusafir is perhaps the most influential handbook in the history of medical science, and Gerrit Bos's provides invaluable insight into the medical theory of Book Seven.

Key features: High quality full color photographs and descriptive texts on the location and removal of the organs from the mouse Instructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysis Full color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achieved All in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader 'from the mouse to the microscope', it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.

Guest edited by Drs Sarah Vossoughi and Brie Stotler, this issue of Clinics in Laboratory Medicine will cover several key areas of interest related to Pediatric Transfusion Medicine. This issue is one of four selected each year by our series Consulting Editor, Dr. Milenko Tanasijevic. Articles in this issue include but are not limited to: Transfusion in the Pediatric Patient: Review of Evidence Based Guidelines, Transfusion in the Neonatal Patient: Review of Evidence Based Guidelines, Massive Transfusion in the Pediatric Patient, Pediatric Hemovigilance and Adverse Transfusion Reactions, Inventory Management and Product Selection in Pediatric Blood Banking, Evaluation and Management of Coagulopathies and Thrombophilias in the Pediatric Patient, Transfusion and Cellular Therapy in Pediatric Sickle Cell Disease, Cellular Therapy in Pediatric Hematologic Malignancies, Hemolytic Disease of the Fetus and Newborn: Historical and Current State, Novel Blood Component Therapies in the Pediatric Setting, and more.

This book shows how the discipline of pathology fits into society and interfaces with science and medicine. It focuses on anatomical pathology and covers the practice of laboratory medicine in the clinical setting. The book is helpful for health professionals, especially anatomical pathologist.

These practical books written by members of the British Association of Medical Managers (BAMM) help clinical directors tackle their role as medical managers. They provide information and guidance, to enable their readers to benefit from the sharing of learning, good ideas and best practice. 'What is innovative about this series is the focus. Focused training is the norm. Yet the clinician in management makes do with generic management texts which, excellent as they may be, do not recognise the enormous diversity of today's NHS. Managing a pathology service is just not the same as managing a cardiac surgery service. This series is about providing help with the context and practicalities of managing directorates.' Peter Lees and Jenny Simpson in the Series Foreword Clinical Director of Pathology is for consultants considering taking up the role of clinical director, and those actually doing the job. It is also useful for laboratory business managers as an induction to pathology. It summarises the key management issues within pathology and is based on practical case studies rather than theoretical management concepts. It highlights a number of key areas that clinical directors of pathology should be tackling in order to maintain the quality and cost effectiveness of their service.

Guide to Forensic Pathology provides a concise overview of forensic pathology to those who wish to know the basics but lack formal forensic training. Both fascinating and practical, this book explains everything from who the experts are in death investigation and what their roles are to how effective testimonies are presented in court. The importance of forensic DNA testing is emphasized with a separate section in this timely reference guide.

This volume begins with a summary of the classical genetic studies and molecular genetic studies of the most common diseases, and indicates what makes them amenable to analysis and treatment. A range of possible future therapeutic options are discussed, from conventional drug targets through to gene therapy. The final chapters assess the value of diagnosis and prediction of the inheritance of various diseases.