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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > HIV / AIDS
Winner, 2021 Joseph W. Elder Prize in the Indian Social Sciences Winner, 2021 Ruth Benedict Prize, Association for Queer Anthropology Hijras, one of India's third gendered or trans populations, have been an enduring presence in the South Asian imagination-in myth, in ritual, and in everyday life, often associated in stigmatized forms with begging and sex work. In more recent years hijras have seen a degree of political emergence as a moral presence in Indian electoral politics, and with heightened vulnerability within global health terms as a high-risk population caught within the AIDS epidemic. Hijras, Lovers, Brothers recounts two years living with a group of hijras in rural India. In this riveting ethnography, Vaibhav Saria reveals not just a group of stigmatized or marginalized others but a way of life composed of laughter, struggles, and desires that trouble how we read queerness, kinship, and the psyche. Against easy framings of hijras that render them marginalized, Saria shows how hijras makes the normative Indian family possible. The book also shows that particular practices of hijras, such as refusing to use condoms or comply with retroviral regimes, reflect not ignorance, irresponsibility, or illiteracy but rather a specific idiom of erotic asceticism arising in both Hindu and Islamic traditions. This idiom suffuses the densely intertwined registers of erotics, economics, and kinship that inform the everyday lives of hijras and offer a repertoire of self-fashioning beyond the secular horizons of public health or queer theory. Engrossingly written and full of keen insights, the book moves from the small pleasures of the everyday-laughter, flirting, teasing-to impossible longings, kinship, and economies of property and substance in order to give a fuller account of trans lives and of Indian society today.
Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors' hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.
Thanks to enormous funding for educational programs, the whole world ?knows? that HIV causes AIDS. But is what we know compatible with the facts? This book challenges the conventional wisdom on this issue. Collating and analyzing, for the first time, the results of more than two decades of HIV testing, it reveals that the common assumptions about HIV and AIDS are incompatible with the published data. Among the many topics explored are the failings of HIV testing, statistical evidence that HIV is neither sexually transmitted nor increasingly prevalent, and problems caused by the differing diagnostic criteria for AIDS around the world. But how could everyone have been so wrong for so long? This vital question, unaddressed in previous works questioning the HIV-AIDS connection, is central to this book. The author considers comparable missteps of modern science, and discusses how funding influences discovery in today's scientific circles.
Though more than 150,000 AIDS-related deaths have been reported worldwide and between 5 and 10 million people are now infected with its precursor, HIV-1, the deadly and relatively new AIDS virus is still a mystery. AIDS and the Social Sciences: Common Threads, an enlightening examination of the AIDS epidemic from the viewpoints of various social sciences, provides us with clues to that mystery. The essays' original research and firsthand accounts from social scientists offer an excellent overview of the research agendas and directions for a disease that is an increasing presence in our society. Sociologists, geographers, anthropologists, psychologists, social workers, and people in government agencies converge in this book to discuss the social, political, economic, legal, moral, and ethical issues related to AIDS. Their methods of approaching the study of AIDS range from a case study approach to survey research to participant observation. Among the topics examined in this distinctive collection are the geographic origins of AIDS, the psychosocial aspects of AIDS, the impact of AIDS on women and children, and the federal funding patterns of AIDS-related research. One chapter traces the diffusion of the pandemic in major urban areas, smaller cities, and finally rural America. Another documents the devastating impact the disease has had on central and East Africa, some areas of which have as many as one in four adults who are HIV-infected. AIDS and the Social Sciences could serve as a primary or supplemental text for college courses and is an important resource for anyone interested in social science or public health.
Today, AIDS has been indelibly etched in our consciousness. Yet it was less than twenty years ago that doctors confronted a sudden avalanche of strange, inexplicable, seemingly untreatable conditions that signaled the arrival of a devastating new disease. Bewildered, unprepared, and pushed to the limit of their diagnostic abilities, a select group of courageous physicians nevertheless persevered. This unique collective memoir tells their story. Based on interviews with nearly eighty doctors whose lives and careers have centered on the AIDS epidemic from the early 1980s to the present, this candid, emotionally textured account details the palpable anxiety in the medical profession as it experienced a rapid succession of cases for which there was no clinical history. The physicians interviewed chronicle the roller coaster experiences of hope and despair, as they applied newly developed, often unsuccessful therapies. Yet these physicians who chose to embrace the challenge confronted more than just the sense of therapeutic helplessness in dealing with a disease they could not conquer. They also faced the tough choices inherent in treating a controversial, sexually and intravenously transmitted illness as many colleagues simply walked away. Many describe being gripped by a sense of mission: by the moral imperative to treat the disempowered and despised. Nearly all describe a common purpose, an esprit de corps that bound them together in a terrible yet exhilarating war against an invisible enemy. This extraordinary oral history forms a landmark effort in the understanding of the AIDS crisis. Carefully collected and eloquently told, the doctors' narratives reveal the tenacity and unquenchable optimism that has paved the way for taming a 20th-century plague.
The advent of AIDS has led to a revival of interest in the historical relationship of disease to society. There now exists a new consciousness of AIDS and history, and of AIDS itself as an historic event. This provides the starting-point of this collection of essays. Its twin themes are the ‘pre-history’ of the impact of AIDS, and its subsequent history. Essays in the section on the ‘pre-history’ of AIDS analyse the contexts against which AIDS should be measured. The section on AIDS as history presents chapters by historians and policy scientists on such topics as British and US drugs policy, the later years of AIDS policies in the UK and the emergence of AIDS as a political issue in France. A final chapter looks at the archival potential in the AIDS area. As a whole the volume demonstrates the contribution that historians can make in the analysis of near-contemporary events.
Dawning Answers charts the legacy of the global HIV/AIDS epidemic to the theory and practice of public health. Richly detailed chapters describe how advances in techniques and startegies to monitor health events, develop public policy, set funding priorities, mobilize communities, support the adoption of safer behaviors, ensure access to needed prevention and treatment services, and involve affected populations in public health research, intervention, and evaluation, all owe a substantial debt to those who have adapted, redefined, and extended these techniques and startegies in response to HIV/AIDS. The book offers thoughtful analyses from experts in various fields and disciplines. Although most of the examples reflect the U.S. experience, relevant examples from other countries are cited, and an entire chapter is devoted to the evolving impact of HIV/AIDS on global health and development. Devastating as the losses from AIDS have been, the many public health lessons learned as a result of the epidemic have positively influenced other domains of public health and will continue to exert an influence on new approaches to health assessment, policy development, and assurance.
This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines.
It's been likened to a plague, but AIDS was never just a health crisis. The second of a series on grieving the death of a friend, Grief and AIDS: Thirty Years of Burying Our Friends, revisits a time when people with AIDS were also victims of bigotry and discrimination. In stories about Ryan White, ACT UP, the Names Project, red ribbons and more, you'll learn why friends made all the difference: not just caregiving or memorializing, but changing the way society confronts the medical establishment and government to demand action.
In the 15 years of the acquired immunodeficiency syndrome (AIDS) pandemic much has been learnt about its natural history and complications. It is clear that the lung is a major target organ both for the human immunodeficiency virus (HIV), and a wide array of infectious and non-infectious pulmonary complications. A great deal of information on the epidemiology, microbiology, immunology, clinical features, diagnosis and management of these pulmonary complications has accumulated during the past 15 years. Given the enormous explosion in information, it is now timely to bring together this knowledge in this 25-chapter volume on AIDS and respiratory medicine. The contributors to this volume are prominent epidemiologists, doctors, microbiologists and scientists from Europe, USA and Africa. Professors Chretien and Enarson give a masterful account of the epidemiology of lung complications of HIV. Drs Zumla, Rowland Jones and Professor McMichael give a detailed summary of the lung immune responses to HIV. They outline normal lung defenses and discuss the consequences of HIV infection on them. The pulmonary radiological features of HIV and its complications as seen in the USA and Europe are illustrated by Professors Armstrong and Dee and this is compared and contrasted by Professor Tshibwabwa-Tumba who brings together his vast experience of chest X-rays in AIDS patients from Central Africa. Drs O'Doherty and Miller deal with the uses, and potential applications, of nuclear medicine in imaging of the chest in AIDS patients."
This book examines the issues surrounding the growing epidemic of women and children with HIV and AIDS. It explores such issues as discrimination in employment, housing, health care, and education, and looks at medical testing, confidentiality, reproductive freedom, income assistance, child welfare, and child custody. Focusing on the federal and state statutes that protect women and children with HIV and AIDS from discrimination, this book also examines the statutes that govern the operation of the public systems to which significant numbers of women with HIV and AIDS turn to for financial and medical needs, housing assistance, and social services. Clear and accessible, this book is vital reading for anyone interested in learning more about the policies, provisions, and legal concepts surrounding this issue.
This book explores the strategies, plans and programs for responding to the HIV/AIDS epidemic in the United States. When one of our fellow citizens becomes infected with the human immunodeficiency virus (HIV) every 9-1/2 minutes, the epidemic affects all Americans. Without treatment, the virus slowly debilitates a person's immune system until they succumb to illness. The epidemic has claimed the lives of nearly 600,000 Americans and affects many more. We have the knowledge and tools needed to slow the spread of HIV infection and improve the health of people living with HIV. Despite this potential, however, the public's sense of urgency associated with combating the epidemic appears to be declining. Unless we take bold actions, we face a new era of rising infections, greater challenges in serving people living with HIV, and higher health care costs. (Imprint: Nova)
Historically, the fields of public health and human rights have remained largely separate. The AIDS pandemic, however, made it clear that a complex relationship exists between the two fields. Women and children have proven to be extremely vulnerable to infection with HIV due to their inability to protect themselves in intimate relationships, their sexual exploitation, and their lack of economic and educational alternatives. On the other hand, coercive government policies aimed at controlling the AIDS pandemic often infringe on the rights of individuals known or suspected of having AIDS, and decrease the effectiveness of public health measures. Protecting and promoting human rights is becoming one of the key means of preserving the health of individuals and populations. A penetrating analysis of the close relationship between public health and human rights, this book makes a compelling case for synergy between the two fields. Using the AIDS pandemic as a lens, the authors demonstrate that human health cannot be maintained without respect for the dignity and rights of persons, and that human rights cannot be deemed adequate and comprehensive without ensuring the health of individuals and populations. In the course of their analysis, Gostin and Lazzarini tackle some of the most vexing issues of our time, including the universality of human rights and the counter-claims of cultural relativity. Taking a cue from environmental impact assessments, they propose a human rights impact assessment for examining health policies. Such a tool will be invaluable for evaluating real-world public health problems and is bound to become essential for teaching human rights in schools of public health, medicine, government, and law. The volume critically examines such issues as HIV testing, screening, partner notification, isolation, quarantine, and criminalization of persons with HIV/AIDS, all within the framework of international human rights law. The authors evaluate the public health effects of a wide range of AIDS policies in developed as well as developing countries. The role of women in society receives special emphasis. Finally, the book presents three case histories that are important in the HIV/AIDS pandemic: discrimination and the transmission of HIV and tuberculosis in an occupational health care setting; breast feeding in the least developed countries; and confidentiality and the right of sexual partners to know of potential exposure to HIV. The cases challenge readers with some of the complex questions facing policy-makers, scientists, and public health professionals, and exemplify a method for analysing these problems from a human rights perspective. Gostin and Lazzarini have written a book that will be a valuable addition to the libraries of public health teachers and practitioners, legal scholars, bioethicists, policy makers, and public rights activists.
This ground-breaking work is the first book to present a Darwinian perspective on infectious disease. It views disease-producing bacteria and viruses as parasites and explains the history of disease as a host-parasite relationship, one which can evolve in many different ways and with radically different effects on the host population. The author's evolutionary approach is interdisciplinary, drawing on theory and example from the fields of epidemiology, molecular genetics, biochemistry, physiology, evolutionary ecology, and the ecology of populations and communities.
The rapidly proliferating research on the human immunodeficiency
virus (HIV), now well in its second decade, continues to generate
new information at a rate heretofore unparalleled in medicine. As a
direct result, the increasing variety of methods for the
prevention, diagnosis, and treatment of HIV and AIDS has made it
difficult for physicians to keep abreast of the optimal management
approaches in the field. The HIV Manual is an immensely practical,
accessible, and up-to-date summary of the wide range of clinically
relevant information on HIV-infected adults. It deals with the key
issues and frequently encountered problems in HIV clinical care,
and includes a special section on the symptom-based approach to
diagnosis. In addition, this concise reference contains several
chapters discussing topics rarely covered in similar books on the
subject, such as HIV testing, initial evaluation, future anti-HIV
therapies, alternative therapies, and nutrition.
AIDS in the World, Vol. 1, published in 1992, was the first full analysis of mankind's global confrontation with this disease. The AIDS scene, however, spurred by the infusion of enormous monetary allocations, and the participation of thousands of health care professionals, researchers, and social workers, has been changing so rapidly that the need for a second volume was felt much earlier than expected. In AIDS in the World II, the authors extend the international comaprisons from 38 countries to the entire world, and show that the AIDS pandemic has become increasingly fragmented within the world population. They present data that takes the discussion beyond the current understanding of the vulnerability of nations and communities to the worldwide spread of HIV, engaging in a detailed exploration of the social strategies that have enabled individuals to avoid infection. Greater emphasis is placed upon the vulnerabilities of different age and sex groups, such as infants, children and women.
AIDS in the World II charts a course into the future based on a clear analysis of the global pandemic and response, the crucial lessons learned from the first decade, and the understanding of the scientific and social dimensions of the HIV challenge. The book explains how the diversity of reactions to the pandemic has contributed to a more specific understanding of the determinants of our vulnerability to HIV/AIDS, and offers a blueprint for an expanded global prevention effort. Intended to serve the information needs of all professionals involved in AIDS research and care, this volume's accessibility and clarity of writing also make it appropriate for the general reader.
Coping with disaster is an overwhelming and often baffling task for survivors, rescue workers, and clinicians. This volume looks in depth at how people experience trauma and suggests practical strategies for treatment. The authors examine issues ranging from the biological basis of posttraumatic stress reaction to the psychosocial and fictional construction of terror, and disasters ranging from random acts of violence to war. From Chernobyl to Desert Storm, from Kentucky floods to Norwegian avalanches, the authors explore the effects of trauma on adults and children. They find certain commonalities in human response to disasters of all kinds, and hold that by understanding these partially predictable patterns of reaction, mastery of chaos, and finally recovery can occur. Based on their comprehensive analysis, they suggest disaster intervention strategies that emphasize recognition of the psychological effects of trauma, as well as preparedness and prevention.
The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume.
Skin diseases are common problems in patients with HIV infection and AIDS. Patients with HIV infection may present first to the dermatologist or to many other groups of physicians. This book is designed to help dermatologists and nondermatologists alike to recognize the cutaneous manifestations of HIV infection and AIDS so that diagnosis can be made quickly and therapy begun as soon as possible. It covers the entire spectrum of HIV associated cutaneous diseases and emphasizes how they present in immunocompromised patients. Each entity is discussed in detail, including clinical presentation, histopathological findings, morphology and treatment. The text is accompanied by colour photos of the highest quality. The latest treatments are described, including Highly Active Antiretroviral Therapy (HAART). While HAART has transformed the lives of patients with HIV and AIDS, these medications have side effects and the authors reinforce the warning that HAART is not a cure.
This book first discusses how depression and anxiety occur more frequently in people living with HIV/AIDS than in the general population. Anxiety and depression increase the morbidity of HIV by causing poor adherence to treatment, increased risk for suicide, greater chance for recurrence and various other significant mechanisms. The authors present an analysis of sociological research showing the prevalence of stigma and discrimination against patients with HIV infection at the dental office. Fear of stigma is a key factor in reducing the willingness to disclose HIV status. The recommended treatment for chronic hepatitis C virus infection with HIV coinfection is reviewed, focusing on the pharmacokinetics and pharmacology of drug-drug interactions between antiretroviral therapy and direct-acting antivirals. Insight on the long road towards the eradication of HIV/AIDS is discussed in an effort to achieve sustainable development goals and targets by 2030. Studies conducted in relation to biomedical, structural, behavioural and technological interventions are cited to substantiate this discussions. The closing chapter outlines updated recommendations guiding healthcare professionals to employ treatment as prevention. A discussion of the public health measures necessary to promote the success of treatment as prevention is also included.
The first personal documentary about AIDS to be published, "Borrowed Time" remains as vividly detailed as the best novel and as lucidly observed as the fiercest journalism. It is a cry from the heart against AIDS as it was in the early stages of the plague and against the intolerance that surrounded it. In equal parts, it is a supremely moving love story and a chronicle of the deep commitment and devotion that Paul Monette felt for Roger Horwitz from the night of their first meeting in Boston in the mid-1970s to Roger's diagnosis a decade later and through the last two years of his life, when fighting the disease together became a full-time occupation. This is not a book about death but a book about living while dying and the full range of emotions provoked by that transition -- sorrow, fear, anger, among them. It is a document essential to the history of the gay community; vital for anyone reading about AIDS; and one of the most powerful demonstrations of love and partnership to be found in print.
Project Inform, the nation's leading community-based AIDS treatment information and advocacy organization, presents the first comprehensive, user-friendly guide to all the drugs most used by people with HIV/AIDS. This completely updated edition includes profiles of the newest and most recently approved drugs and laboratory tests, including protease inhibitors and viral load tests -- and in-depth discussions on how best to use these advances to create effective, long-term treatment strategies. Acclaimed for its accurate but nontechnical language, the handbook is easily accessible by way of an extensive master index. Features include:
The HIV Drug Book is written expressly for people with HIV/AIDS and their caregivers, friends and family members, and will be invaluable to physicians who must struggle with the overwhelming demands of this rapidly changing field. |
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