THE PIONEERING WORK IN HIV MEDICINE, COMPLETELY REVISED FOR THE FIRST TIME SINCE 2012 The 17th edition of Bartlett's Medical Management of HIV Infection offers the best-available clinical guidance for treatment of patients with HIV. Edited by preeminent and pioneering authorities in HIV research and clinical care, it has earned its status as the definitive work for physicians, physician assistants, nurse practitioners, pharmacists, and anyone working in the care of persons with HIV. Updated to reflect the most recent innovations in HIV prevention and therapy, this text balances new and old approaches to produce a guide to clinical management in any setting. Coverage includes: * New approaches to prevention of HIV and prevention of infection in patients with HIV * Laboratory protocols for screening and treatment * Antiretroviral therapies (including dosage and adverse effects and drug interactions ) * HIV treatment in resource-limited settings * Management of infections A portable, navigable guide to an exquisitely complex field, Bartlett's Medical Management of HIV Infection is the continuing standard for practice and education in the field of HIV.

It is now forty years since the discovery of AIDS, but its origins continue to puzzle doctors, scientists and patients. Inspired by his own experiences working as a physician in a bush hospital in Zaire, Jacques Pepin looks back to the early twentieth-century events in central Africa that triggered the emergence of HIV/AIDS and traces its subsequent development into the most dramatic and destructive epidemic of modern times. He shows how the disease was first transmitted from chimpanzees to man and then how military campaigns, urbanisation, prostitution and large-scale colonial medical interventions intended to eradicate tropical diseases combined to disastrous effect to fuel the spread of the virus from its origins in Leopoldville to the rest of Africa, the Caribbean and ultimately worldwide. This is an essential perspective on HIV/AIDS and on the lessons that must be learned as the world faces another pandemic.

'I read the book in one go. I laughed and cried like a baby, and was transported back to a time of innocence, clouded by the enormity of the harsh reality . . . Just amazing' CATHERINE ZETA JONES 'As it happens, I was also a Jill in the eighties - but not half as good a Jill as real Jill' DAWN FRENCH 'Jill met the crisis head on . . . She held the hands of so many men. She lost them, and remembered them, and somehow kept going' RUSSELL T DAVIES A heartbreaking, life-affirming memoir of love, loss and cabaret through the AIDS crisis, from IT'S A SIN's Jill Nalder When Jill Nalder arrived at drama school in London in the early 1980s, she was ready for her life to begin. With her band of best friends - of which many were young, talented gay men with big dreams of their own - she grabbed London by the horns: partying with drag queens at the Royal Vauxhall Tavern, hosting cabarets at her glamorous flat, flitting across town to any jobs she could get. But soon rumours were spreading from America about a frightening illness being dubbed the 'gay flu', and Jill and her friends now found their formerly carefree existence under threat. In this moving memoir, IT'S A SIN's Jill Nalder tells the true story of her and her friends' lives during the AIDS crisis -- juggling a busy West End career while campaigning for AIDS awareness and research, educating herself and caring for the sick. Most of all, she shines a light on those who were stigmatised and shamed, and remembers those brave and beautiful boys who were lost too soon. 'Thank God for people like [Jill] . . . I cannot recommend this book highly enough' MICHAEL BALL 'An engaging, moving account' TIMES SATURDAY REVIEW 'Simultaneously devastating and uplifting' GRAZIA 'Engrossing, heart-breaking and inspiring' MATT CAIN

The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent.

These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients.

Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Gotte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang."

Almost four decades after the discovery of HIV/AIDS, the world continues to grapple with this public health challenge. Thinking Differently about HIV/AIDS explores the limits of mainstream approaches to the HIV/AIDS epidemic and challenges readers to develop alternate solutions, emphasizing the value of critical social science perspectives. The contributors investigate traditions of inquiry - governmentality studies, institutional ethnography, and Indigenous knowledges, among others - to determine what these perspectives can bring to HIV/AIDS research, policy, and programming. Ultimately, this book demonstrates how and why critical social science is necessary for rethinking research and action required to address the epidemic.

In 2008 it was believed that HIV/AIDS was without doubt the worst epidemic to hit humankind since the Black Death. The first case was identified in 1981; by 2004 it was estimated that about 40 million people were living with the disease, and about 20 million had died. Yet the outlook today is a little brighter. Although HIV/ AIDS continues to be a pressing public health issue the epidemic has stabilised globally, and it has become evident it is not, nor will it be, a global issue. The worst affected regions are southern and eastern Africa. Elsewhere, HIV is found in specific, usually, marginalised populations, for example intravenous drug users in Russia. Although there still remains no cure for HIV, there have been unprecedented breakthroughs in understanding the disease and developing drugs. Access to treatment over the last ten years has turned AIDS into a chronic disease, although it is still a challenge to make antiviral treatment available to all that require it. We also have new evidence that treatment greatly reduces infectivity, and this has led to the movement of 'Treatment as Prevention'. In this Very Short Introduction Alan Whiteside provides an introduction to AIDS, tackling the science, the international and local politics, the demographics, and the devastating consequences of the disease. He looks at the problems a developing international 'AIDS fatigue' poses to funding for sufferers, but also shows how domestic resources are increasingly being mobilised, despite the stabilisation of international funding. Finally Whiteside considers how the need to understand and change our behaviour has caused us to reassess what it means to be human and how we should operate in the globalizing world. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.