Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail. The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials.

The new ASM Handbook, Volume 11: Failure Analysis and Prevention is a valuable resource for failure analysts, engineers, and technical personnel who are looking to identify the root cause(s) of failures and to prevent future failures. The editors and hundreds of authors and peer reviewers worked tirelessly to revise Volume 11 from its 2002 and 1986 editions with the goal to provide the "go-to" reference for those confronted with the failure of a machine or component. Volume 11 contains divisions devoted to the practice of failure analysis, tools and techniques, fatigue and fracture, environmental and corrosion-related failures, wear failures, and distortion. The emphasis is on general principles with the widest applicability to situations that the reader is likely to encounter. For the specific considerations associated with common types of components, the companion ASM Handbook, Volume 11A: Analysis and Prevention of Component and Equipment Failures, is scheduled for publication in 2021.

Solar Energy Harvesting, Conversion and Storage: Materials, Technologies and Applications focuses on the current state of solar energy and the recent advancements in nanomaterials for different technologies, from harnessing energy to storage. The book covers different aspects of advanced nanomaterials for solar energy, rapid developments in solar thermal and hot water systems, and PV and CSP technologies. The book also discusses storing harnessed solar/heat energy using different available energy storage technologies, including phase change materials (PCMs), batteries, and supercapacitors. Various applications such as agriculture and aquaculture, desalination, domestic appliances, and transport are explored, as well.

Corrosion of Steel in Concrete Structures, Second Edition covers the corrosion of steel reinforced concrete, along with a variety of new topics and future trends. Sections discuss the theoretical concepts of corrosion of steel in concrete structures, analyze the variety of reinforcing materials and concrete, including stainless steel and galvanized steel, cover measurements and evaluations, such as electrochemical techniques and acoustic emission, review protection and maintenance methods, and analyze modeling. Topics covered include the steel/concrete interface, the influence of steel microstructure on its corrosion in concrete, data collection and analysis on chloride-induced corrosion, corrosion detection devices, and new advances.

Every bit of information that circulates the internet across the globe is a pulse of light, that at some point will need to be converted to an electric signal in order to be processed by the electronic circuitry in our data centers, computers, and cell phones. Photodetectors (PD's) perform this conversion with ultra high speed and efficiency, in addition to being ubiquitously present in many other devices ranging from the mundane TV remote controls, to ultra high resolution instrumentation used in Laser Interferometer Gravitational Wave Observatory (LIGO) that reach the edge of the universe and measure gravitational waves. The second edition of "Photodetectors" fully updates the popular first edition with updated information covering the state-of-the-art in modern photodetectors. The 2nd edition starts with basic metrology of photodetectors and common figures-of-merit to compare various devices. It follows with chapters that discuss single-photon detection with Avalanche Photodiodes; organic photodetectors that can be inkjet printed; and silicon-germanium PDs popular in burgeoning field of Silicon Photonics. Internationally recognized experts contribute chapters on one-dimensional, nanowire, PDs as well as high speed zero-dimensional, quantum dot, versions that increase the spectral span as well as speed and sensitivity of PDs and can be produced on various substrates. Solar-blind PDs that operate in harsh environments such as deep space, or rocket engines, are reviewed and new devices in GaN technology . Novel Plasmonic PDs, as well as devices which employ micro-plasma of confined charge in order to make devices that overcome speed limitation of transfer of electronic charge, are covered in other chapters. Using different, novel technologies, CMOS compatible devices are described in two chapters, and ultra high speed PDs that use low-temperature-grown GaAs (LT-GaAs) to detect fast THz signals are reviewed in another chapter. Photodetectors used in application areas of Silicon-Photonics and Microwave-Photonics are reviewed in final chapters of this book. All chapters are of a review nature, providing a perspective of the field before concentrating on particular advancements. As such, the book should appeal to a wide audience that ranges from those with general interest in the topic, to practitioners, graduate students and experts who are interested in the state-of-the-art in photodetection.

Graphene Quantum Dots: Biomedical and Environmental Sustainability Applications provides an overview of fundamentals and advances in applications of graphene quantum dots. Concepts covered include a brief introduction on the topic, an overview of structure and chemistry, fundamental properties of different characterization techniques, methods for the preparation of graphene quantum dots, and recent and emerging applications in various fields including antimicrobial therapy, bioimaging, biomedical tools development and clean energy for environmental sustainability. The book is a critical resource in materials selection for biomedical and environmental sustainability applications as well as various advanced imaging, disinfectant and environmental remediation technologies. As such, it is suitable for those in academia working in the discipline of materials science and engineering and practitioners working on biomedical tool development and environmental remediation.

Biomaterials for Neural Tissue Engineering covers a range of materials and technologies used for regenerating or repairing neural tissue. With a strong focus on biomaterials and scaffolds, the book examines the testing and evaluation pathway for in-vitro and in-vivo testing trials. This book introduces the reader to the fundamentals of the nervous system from a tissue engineering perspective and goes on to describe contemporary technologies used in the development of neural repair materials, as well as currently available biomaterials suitable for neural tissue repair and regeneration. This detailed reference is ideal for those who are new to using biomaterials in tissue engineering, particularly those interested in the nervous system, including academics and early career researchers in the fields of materials science, regenerative medicine, biomedical engineering and clinical sciences.

Protein-based Nanocomposites for Tissue Engineering details the design, development, efficacy and tissue engineering applications of a range of protein-based nanocomposite materials. Protein-based nanocomposites offer advantageous properties in that they are biodegradable, biocompatible, nonantigenic, highly stable and possess strong binding capacity. These unique properties make protein-based nanocomposite carriers promising candidates for controlled cell delivery in tissue engineering. This book covers a selection of protein types in their nanocomposite form, from albumin and keratin to collagen and silk. Each protein nanocomposite is described in detail, exploring their application in cell delivery and tissue engineering. The design, development, properties and molecular mechanism of protein-based nanocomposites is thoroughly discussed before going on to analyze the advantages and limitations of these useful materials, making this book an ideal resource for readers who want to explore biocompatible and naturally derived material options for tissue engineering applications. Academics and researchers in the fields of materials science, biomedical engineering, regenerative medicine and nanotechnology will find the book a must have.

Principles of Biomaterials Encapsulation: Volume Two provides an expansive and in-depth resource covering the key principles, biomaterials, techniques and applications of encapsulation in translational medicine. The book details the various biomaterials available for encapsulation, including polymers, natural and synthetic biomaterials, porous materials, and more. The advantages and disadvantages of conventional and contemporary biomaterials for encapsulations are reviewed, along with advice on the most effective materials for both shell and core. The final part of the book describes a broad range of applications in regenerative medicine, uniquely bringing encapsulation into the worlds of translational medicine and tissue engineering. This book enables readers to learn about the pros and cons of different biomaterials for encapsulation, as well as how they can be utilized in many bodily systems and tissues, such as the respiratory, digestive, endocrine and cardiovascular systems. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine.

Green Sustainable Process for Chemical and Environmental Engineering and Science: Applications of Advanced Nanostructured Materials in Wastewater Remediation reviews recent applications of nanostructured materials for remediation, their preparation, characterization and efficiency for water remediation technologies. The book provides ideas on how nanomaterials are the real solution to water purification or new environmental threat. Sections cover nanomaterial adsorbents, functionalized magnetic nanomaterials, nanostructured polymer hydrogels, carbon nanomaterials, biogenic nanoparticles, green chemistry concepts, aqua defluoridation, and advanced remediation techniques. The book also includes the current status of wastewater treatment using nanomaterials, along with challenges and perspectives for further improvements.

Principles of Human Organs-on-Chips covers all aspects of microfluidic organ-on-a-chip systems, from fabrication to application and commercialization. Organ-on-a-chip models are created to mimic the structural, microenvironmental and physiological functions of human organs, providing the potential to bypass some cell and animal testing methods. This is a useful platform with widespread applications, frequently in drug screening and pathological studies. This book offers a comprehensive and authoritative reference on microfluidic organs-on-chips, spanning all key aspects from fabrication methods, cell culture systems and cell-based analysis, to dedicated chapters on specific tissue types and their associated organ-on-a-chip models, as well as their use as disease models, drug screening platforms and more. Principles of Human Organs-on-Chips helps materials scientists and biomedical engineers to better understand the specific requirements and challenges in the design and fabrication of organ-on-a-chip devices. This book also bridges the knowledge gap between medical device design and subsequent clinical applications, allowing medical professionals to easily learn about related engineering concepts and techniques.

Biopolymers: Synthesis, Properties, and Emerging Applications presents the state-of-the-art in biopolymers, bringing together detailed information on synthesis strategies, processing and cutting-edge applications. The book begins by introducing the synthesis, processing and structural and functional properties of smart biopolymers and bionanocomposites. Subsequent chapters focus on the synthesis and preparation of biopolymers with valuable properties or for specific advanced applications, including piezoelectric properties, shape memory properties, biodegradable polymer blends, synthesis and assembly of nanomaterials, synthesis of green biopolymers, and catalytic synthesis of bio-sourced polyesters and polycarbonate, as well as applications in active food packaging, water purification, biomedicine, 3D printing, and automotive. Throughout the book, there are analyses of different synthesis strategies and processing methods and their role and use in different fields of application, whilst the important challenges relating to scalable processing and shaping and micro and nano structuration are also discussed. The book also strives to balance the synthetic aspects of biopolymers with physical principles, highlighting biopolymer-based architectures including composite or hybrid conjugates, providing in-depth discussion of important examples of reaction mechanisms, and exploring potential applications of biopolymer and conjugates, ranging from physical to chemical and biological systems.

ELEMENTS OF AERODYNAMICS An accessible and hands-on textbook filled with chapter objectives, examples, practice problems, sample tests, and an online aero-calculator In Elements of Aerodynamics, Professor Oscar Biblarz delivers a concise and fundamentals-oriented approach to aerodynamics suitable for both undergraduate and graduate-level students. The text offers numerous problems, examples, and check tests, allowing readers to gain and cement their knowledge through hands-on practice. Using a unique blend of fundamentals, the book provides students with a new approach to high lift airfoils including examples designed to complement the theory. It covers the most vital information on incompressible and compressible flow over two-dimensional and three-dimensional wings. A companion website that includes an interactive aero-calculator and additional student resources makes this a suitable text for online, hybrid, and distance learning. Readers will also find: A concise introduction to units and notation with discussion of the proper usage of dimensionless coefficients in aerodynamics, featuring descriptions of airflow as an incompressible and compressible low-viscosity medium past streamlined wings Comprehensive re-evaluation of the fundamentals of fluid dynamics, including the differential control volume approach and formulation of lift, drag, and pitching moments for thin, attached boundary layers over slender wings at high angles of attack Practical applications of mass, momentum, and energy relations, derived from Euler's equation, Bernoulli's equation, and the Kutta-Joukowski theorem Selected treatment of transonic and hypersonic aerodynamic aspects, including supercritical airfoils, the non-linear small perturbation potential equation, Newtonian theory, and hypersonic lift and drag Well-suited for students enrolled in an introductory aerodynamics course as part of an engineering program, Elements of Aerodynamics will also earn a place in the libraries of physics students and those interested in basic fluid mechanics.

Water-Formed Deposits: Fundamentals and Mitigation Strategies wholly presents the important issue of deposits in aqueous systems, both industrial and biological. By analyzing causes, mechanisms and mitigation strategies, the book helps researchers/engineers/end-users gain a fundamental understanding of the issues underlying deposit formation and mitigation. It covers numerous, fundamental aspects of water-formed deposits, while also giving an applications' perspective. The book's goal is to assist the reader in his/her understanding of the important issues of scale formation, while also helping with potential solutions.

The new ASM Handbook Volume 11A is a valuable resource for failure analysts, engineers, and technical personnel who are looking to identify the root cause(s) of failures and to prevent future failures. The editors and hundreds of authors and peer reviewers undertook a wholesale revision and expansion of Volume 11 from its 2002 and 1986 editions and succeeded in producing the go-to reference for those confronted with the failure of a machine or component. Volume 11A contains divisions devoted to engineering aspects of failure and prevention, structural life assessment methods, metal manufacturing aspects of failure, and failure analysis of metallic components. The general principles of failure analysis are presented in the companion ASM Handbook, Volume 11: Failure Analysis and Prevention, which was published in 2021. Its divisions cover the practice of failure analysis, tools and techniques, fatigue and fracture, environmental and corrosion-related failures, wear failures, and distortion. Selected articles are published digital first, in advance of the full volume release, at https://dl.asminternational.org/handbooks/book/151/Analysis-and-Prevention-of-Component-and-Equipment

Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields.

Nanotechnology in Fuel Cells focuses on the use of nanotechnology in macroscopic and nanosized fuel cells to enhance their performance and lifespan. The book covers the fundamental design concepts and promising applications of nanotechnology-enhanced fuel cells and their advantages over traditional fuel cells in portable devices, including longer shelf life and lower cost. In the case of proton-exchange membrane fuel cells (PEMFCs), nano-membranes could provide 100 times higher conductivity of hydrogen ions in low humidity conditions than traditional membranes. For hydrogen fuel cell, nanocatalysts (Pt hybrid nanoparticles) could provide 12 times higher catalytic activity. This is an important reference source for materials scientists and engineers who are looking to understand how nanotechnology is being used to create more efficient macro- and nanosized fuel cells.

Structural Mechanics and Design of Metal Pipes: A systematic approach for onshore and offshore pipelines presents a unified and systematic approach to understanding and analyzing the structural behavior of onshore and offshore metallic pipelines. Following an overview of pipeline engineering and pipe fabrication, the mechanics of elastic rings and cylinders is presented as a prelude to structural performance of metal pipes under various loading conditions, which involve pressure and structural loads. The book also discusses special topics, such as geohazards and strain-based design, large-diameter water pipelines, global buckling and mechanically-lined pipes, and outlines approaches for developing state-of-the-art finite element models. In all topics addressed in this book, the mechanical behavior of pipes is related with specific design methods for onshore and offshore pipelines.

Copper Nanostructures: Next-Generation of Agrochemicals for Sustainable Agroecosystems considers the impact of copper-based nanostructures on agri-food sectors. Sections highlight the green synthesis of copper nanoparticles, production mechanisms, eco-safety, and future perspectives, discuss the increasing importance of copper nanomaterials in plant protection applications, describe the use of copper nanostructures in plant science applications, cover antimicrobial applications, explore copper nanostructure applications, and summarize current applications in agroecosystems, such as copper nanoparticles as nanosensors, their negative ecological effects, estimation risks, and more.

Advanced Fibre-reinforced Polymer (FRP) Composites for Structural Applications, Second Edition provides updates on new research that has been carried out on the use of FRP composites for structural applications. These include the further development of advanced FRP composites materials that achieve lighter and stronger FRP composites, how to enhance FRP integrated behavior through matrix modification, along with information on pretension treatments and intelligence technology. The development of new technology such as automated manufacturing and processing of fiber-reinforced polymer (FRP) composites have played a significant role in optimizing fabrication processing and matrix formation. In this new edition, all chapters have been brought fully up-to-date to take on the key aspects mentioned above. The book's chapters cover all areas relevant to advanced FRP composites, from the material itself, its manufacturing, properties, testing and applications in structural and civil engineering. Applications span from civil engineering, to buildings and the energy industry.

Design and Manufacture of Structural Composites provides an overview of the main manufacturing challenges encountered when processing fibre-reinforced composite materials. Composites are unique in that the material is created at the same time as the structure, forming a very close link between the constituents, the manufacturing process and the resulting mechanical performance. This book takes an in-depth look at material choices and the intermediate steps required to convert different fibre and matrix combinations into finished products. It provides an insight into recent developments for each of the manufacturing processes covered, addressing design, cost, rate and mechanical performance. Topics covered include an introduction to composite materials, material preforming and conversion, moulding, digital design and sustainability, which addresses waste reduction, disassembly and fibre recovery. This book has been developed primarily as a teaching resource with contributions from leading experts in the field. The content has evolved from courses given by the authors to mechanical engineering and materials science students, at both undergraduate and postgraduate levels. It also draws upon experience gained during research projects and from leading industry experts. It therefore provides non-specialists with a valuable introduction to composite manufacturing techniques, helping to determine the most suitable manufacturing routes and to understand the challenges associated with the production of high-performance composite components.

Handbook of Surface Improvement and Modification, Second Edition covers additives and the modification processes that determine the surface properties of many materials. These additives can modify or improve scratch and mar resistance, improve gloss or flatten the surface, increase or decrease tack and inhibit staining. Mechanisms of damage, protection and property improvements are also discussed, making this an essential handbook for engineers, researchers and technicians interested in using additives to modify and improve the surface properties of materials. A companion book, Databook of Surface Modification and Additives, is also available with more information on the additives commercially available to improve materials.

Databook of Plasticizers, Third Edition contains data on more than 300 of the most important generic and commercial plasticizers in use today. The data comes from a range of sources beyond plasticizers manufacturers, allowing for a detailed comparison of properties of different plasticizers. Over 100 different data fields are provided, from general information, such as molecular structure and formula, to physical properties, health and safety information, ecological properties, and recommendations regarding appropriate use and performance of each plasticizer. This data book is an essential resource for engineers, technicians and materials scientists responsible for specifying a plasticizer. The book has been updated to reflect the recent changes in plasticizer approvals for production of various materials, including chloroparaffins, refined oil derivatives, and phalates, and also includes data details on a range of new plasticizers that have recently gained market approval. It serves as an ideal companion to the Handbook of Plasticizers.

Inorganic Chemistry in India, Volume 81, the latest release in the Advances in Inorganic Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as Water Oxidation and Oxygen Reduction Reactions: A Mechanistic Perspective, Redox Activity as a Tool for Bond Activations and Functionalizations, Heme/Cu-oxygen Intermediates of Amyloid beta Peptides associated with Alzheimer's Disease, N-Heterocyclic Silylene Coordinated Coinage Metal Complexes: An Itinerary of Their Utilities, Implications of strongly coupled catecholate-based anchoring functionality of a sensitizer dye molecule towards photoinduced electron transfer dynamics, and more. Additional sections cover Application of Ru(edta) complexes in biomimetic activation of small molecules: Kinetic and Mechanistic Impact, and more.

Phase Change Materials for Heat Transfer focuses on how to maximize the heat transfer rate and thermal storage capability of PCMs. Various aspects are covered, including preparation of phase change materials to heat transfer enhancement and characteristics with an emphasis on prominent applications. The book is designed in such a manner to cover the broad definitions, introduction, brief history, preparation techniques, thermophysical properties and heat transfer characteristics with mathematical models, performance-affecting factors and the applications and challenges of PCMs. This handbook will prove invaluable to readers interested in a resource with the latest information in this emerging field.