There is general consensus regarding threshold levels that describe the gray zone on the limits of viability, and gestational age alone should not be used solely in making a decision. This issue will bring light to the latest thoughts and clinical recommendations for delivery during the periviable period. Top thought leaders and clinicians have submitted articles in the following areas: Consequences of Birth at Periviable Gestions on Organ Systems; Medical and Surgical Interventions Before Birth; NICU Care: Nutrition/NEC; Pulmonary Care and Circulatory Support; NICU Stay and Microbiome; and Ethical Considerations and Counseling, to name a few. Readers will come away with the most current content written on this topic and details that can be incorporated into clinical care.

This expansive survey spotlights pervasive issues affecting girls' and women's sexual and reproductive health across the lifecourse. Research from diverse countries around the world analyzes the complex relationships among biological, psychological, sociocultural, and economic issues-particularly in terms of inequities-as they shape women's lives. Major challenges and possibilities for intervention are examined in their national context and with their global implications, including child marriage/motherhood, reproductive care and access, fertility, childbearing, contraception, abortion, HIV/STIs, gender-based violence, sexual pleasure, and menopause. In these forceful dispatches, a consistent human rights perspective emphasizes women's control, autonomy, and agency in all stages of their lives. A sampling of topics covered: Girl child marriage: a persistent global women's health and human rights violation Investigating challenges and resilience among women living with obstetric fistula in Kenya A qualitative exploration of mainstream and social media reflections on abortion A continuum of severity of sexual intimate partner violence among black women in the United States Economic empowerment to improve sexual and reproductive health among women and girls Summarizing an interdisciplinary field on research and practical levels, Global Perspectives on Women's Sexual and Reproductive Health Across the Lifecourse will be an invaluable text for undergraduate and graduate courses in a wide range of fields, including public health, global health, women's studies, sociology, anthropology, gender studies, and human rights.

A generation has passed since a physician first noticed that women who drank heavily while pregnant gave birth to underweight infants with disturbing tell-tale characteristics. Women whose own mothers enjoyed martinis while pregnant now lost sleep over a bowl of rum raisin ice cream. In "Message in a Bottle," Janet Golden charts the course of Fetal Alcohol Syndrome (FAS) through the courts, media, medical establishment, and public imagination.

Long considered harmless during pregnancy (doctors even administered it intravenously during labor), alcohol, when consumed by pregnant women, increasingly appeared to be a potent teratogen and a pressing public health concern. Some clinicians recommended that women simply moderate alcohol consumption; others, however, claimed that there was no demonstrably safe level for a developing fetus, and called for complete abstinence. Even as the diagnosis gained acceptance and labels appeared on alcoholic beverages warning pregnant women of the danger, FAS began to be de-medicalized in some settings. More and more, FAS emerged in court cases as a viable defense for people charged with serious, even capital, crimes and their claims were rejected.

Golden argues that the reaction to FAS was shaped by the struggle over women's relatively new abortion rights and the escalating media frenzy over "crack" babies. It was increasingly used as evidence of the moral decay found within marginalized communities--from inner-city neighborhoods to Indian reservations. With each reframing, FAS became a currency traded by politicians and political commentators, lawyers, public health professionals, and advocates for underrepresented minorities, each pursuingseparate aims.

Preterm birth interrupts the normal developmental progression of most organs, particularly when birth occurs at the lowest level of viability. An immediate task is to successfully transition to a post-natal life without a placental circulation. To do this demands careful management of the cardiorespiratory systems. To best help the fragile preterm infant at this demanding time, care-givers must remember two most pressing goals. These are first to maintain adequacy of gas exchange and delivery, while simultaneously minimizing any secondary injury to the fragile preterm lung. However, after these immediate priorities in the delivery room, the longer term effects of an immature lung development and its associated problems come to the forefront. These problems include the inflammation of perinatal infection, oxygen, and invasive mechanical ventilation. Both the immaturity itself, and secondary lung injury and its inflammation - collectively will often lead to the condition termed bronchopulmonary dysplasia (BPD). Although many of these infants may eventually be discharged to home without a need for oxygen supplementation or pulmonary medications, the long-term impact of interrupted lung development and secondary lung injury remain serious concerns. It is now well recognized that mechanical ventilation is pivotal to developing secondary lung injury and BPD. Consequently, a great deal of time and effort has been put into the development and application of non-invasive ventilator (NIV) approaches to supporting respiratory function in neonates. Since the landmark publication by Gregory and colleagues in 1967, nasal continuous positive airway pressure (nCPAP) has been the most commonly applied approach to NIV. This approach has been supported by the recent generation of randomized controlled trials. However, cumulatively these trials have shown only a small reduction in rates of BPD. Outside of the trial data, despite the wider application of nCPAP, rates of BPD remain relatively unchanged over recent years. This has led to investigations of other NIV approaches including nasal ventilation and high flow nasal cannula therapy. Not only have available modes increased, but so have the interfaces through which these modes may be applied. In the issue of Clinic in Perinatology, readers will find an up-to-date review of non-invasive approaches to supporting preterm respiratory function. This draws on the expertise of leading investigators in the field. This issue reviews the physiologic mechanisms by which the various approaches to NIV may support respiratory function; the evidence base supporting different NIV approaches; and adjunctive aspects of NIV therapy including their use during neonatal transport and the application of other supportive therapies such as inhaled NO.

This book analyses the reasons for relying on behavioural contraception methods among urban 'elites' in India and examines their efficacy in controlling fertility. It also traces variations in contraception choice over the reproductive cycle of women. Although researchers and policy makers generally equate reliance on behavioural contraceptive methods with low levels of education and awareness and lack of desire to control fertility, this perception has been questioned in recent years. The authors' analysis of the first three rounds of the National Family Health Survey (NFHS) data in India reveals that behavioural contraceptive methods are popular in eastern India. Moreover, it is urban educated women who rely on behavioural methods, and are apparently able to regulate fertility quite effectively with such methods. NFHS data, however, has some limitations and this motivates the authors to explore birth control methods through primary surveys of currently married graduate women in Kolkata. The use of behavioural contraception methods is a little researched area globally and this is the first book focusing on the topic in India.

This handbook addresses universal developmental and cultural factors contributing to child and adolescent mental health and well-being across the globe. It examines sociocultural contexts of development and identifies children's and adolescents' perspectives as critical to understanding and promoting their psychological well-being. It details the Promoting Psychological Well-Being Globally project's methodology for data collection and analysis, provides cross-cultural analyses of its findings, and offers a practical model for clinicians and other professionals seeking to apply this knowledge to real-life settings. Featured topics include: Sexual health, gender roles, and psychological well-being in India. Psychological well-being as a new educational boundary in Italy. Mapping psychological well-being in Romania. Youth perspectives on contributing factors to psychological well-being in Sri Lanka. Culturally specific res ilience and vulnerability in Tanzania.Longing for a balanced life - the voices of Chinese-American/immigrant youth in the United States. The International Handbook of Psychological Well-Being in Children and Adolescents: Bridging the Gaps Between Theory, Research, and Practice is an invaluable resources for researchers, clinicians, scientist-practitioners, and graduate students in child and school psychology, social work, public health, positive psychology, educational policy and politics, and maternal and child health.

In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children's future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges that need to be overcome in order to break the intergenerational cycle of obesity. This has profound implications for the way in which scientific, clinical and health policy activities are to be directed in order to combat the so-called epidemic of obesity, as well as diabetes, cancer and cardiovascular disease. The book will be of interest to students, clinicians, researchers and health policy makers who are either seeking an introduction to the area of Developmental Origins of Health and Disease or have a specific interest in the pathogenesis of obesity.

This book presents new findings that deal with different facets of the well-being of children and their relevance to the proper treatment of children. The well-being of children is considered against the background of a wide variety of legal, political, medical, educational and familial perspectives. The book addresses diverse issues from a range of disciplinary perspectives using a variety of methods. It has three major sections with the essays in each section loosely organized about a common general theme. The first section focuses on issues concerning the relation between children’s well-being and autonomy or agency. The second section deals with child well-being insofar as the limits of parental authority are concerned. The third section has a more applied orientation and addresses a variety of public policy controversies involving the interpretation of children’s well-being.

This book brings together a range of theoretical and empirical perspectives on conceptualization, measurement, multidimensional impacts and policy and service responses to address child and family poverty. It illuminates issues and trends through country level chapters, thus shedding light on dynamics of poverty in different jurisdictions. The book is structured into three sections: The first includes introductory chapters canvassing key debates around definition, conceptualization, measurement and theoretical and ideological positions. The second section covers impacts of poverty on specific domains of children’s and families’ experience using snapshots from specific countries/geographic regions. The third section focuses on programs, policies and interventions and addresses poverty and its impacts. It showcases specific interventions, programs and policies aimed at responding to children and families and communities and how they are or might be evaluated. Cross national case studies and evaluations illustrate the diversity of approaches and outcomes.

This book addresses new avenues in child abuse prevention research that will expand our capacity to protect children. These new avenues result from the emergence of new research methods made possible through technologic advances, an understanding of the benefits of cross-disciplinary research and learning and the entrance of many young scholars in the field. The book explores what these avenues produce in terms of clarifying the complex problems that continue to limit our progress in addressing child maltreatment and promoting optimal child development. Specifically, the book showcases individual contributions from emerging scholars and show how these scholars use the frameworks and advanced methods to shape their work, apply their findings and define their learning communities. The book highlights the benefits of creating explicit and extended opportunities for researchers to network across disciplines and areas of interest. The primary authors are young scholars from universities across the U.S. who have worked together as Fellows of the Doris Duke Fellowships for the Promotion of Child Well-Being – seeking innovations to prevent child abuse. Through this program, the Fellows have engaged in a robust self-generating learning network designed to create the type of ongoing professional linkages and decision-making style that fosters an interdisciplinary and team planning approach to research design and policy formation.

Obstetrical emergencies can be among the most stressful events an emergency physician will face in their entire career. The purpose of this book is to provide an evidence-based, practical approach to the wide spectrum of obstetric complications an emergency physician must be prepared to manage throughout all trimesters pregnancy as well as postpartum, including complications of assisted reproductive technology, bleeding, precipitous delivery and preterm labor. Clinical pearls and pitfalls are highlighted throughout. The approach to the pregnant patient with trauma, non-pregnancy-related abdominal pain, or in cardiac arrest is discussed. Updates in the classification and management of the hypertensive disorders of pregnancy are presented. Recent controversies surrounding the use of anti-emetics for first trimester nausea and vomiting and the use of a beta-hCG discriminatory zone for the evaluation of pregnancy of unknown location are also addressed. Obstetrical support services vary widely between different facilities, and Emergency Department Management of Obstetric Complications is written for emergency clinicians in all practice settings. This book provides useful information for daily practice as well as preparation for rarely encountered and potentially life-threatening events.

This handbook addresses universal developmental and cultural factors contributing to child and adolescent mental health and well-being across the globe. It examines sociocultural contexts of development and identifies children's and adolescents' perspectives as critical to understanding and promoting their psychological well-being. It details the Promoting Psychological Well-Being Globally project's methodology for data collection and analysis, provides cross-cultural analyses of its findings, and offers a practical model for clinicians and other professionals seeking to apply this knowledge to real-life settings. Featured topics include: Sexual health, gender roles, and psychological well-being in India. Psychological well-being as a new educational boundary in Italy. Mapping psychological well-being in Romania. Youth perspectives on contributing factors to psychological well-being in Sri Lanka. Culturally specific res ilience and vulnerability in Tanzania.Longing for a balanced life - the voices of Chinese-American/immigrant youth in the United States. The International Handbook of Psychological Well-Being in Children and Adolescents: Bridging the Gaps Between Theory, Research, and Practice is an invaluable resources for researchers, clinicians, scientist-practitioners, and graduate students in child and school psychology, social work, public health, positive psychology, educational policy and politics, and maternal and child health.

Obesity has reached epidemic proportions globally and presents a major challenge to policy makers and clinicians alike. Recent research has suggested that obesity has its origins in early life and that early diet can programme a developing fetus' and young infant's future susceptibility to obesity. This volume contains recent findings presented at the International Conference on Early Nutrition Programming and Health Outcomes in Later Life: Obesity and Beyond - a satellite meeting of the 15th European Congress on Obesity, held in Budapest in April 2007. Basic scientific research, data from epidemiological studies and clinical trial results were all presented during the programme. This volume includes articles discussing the evidence for an effect of early nutrition programming on later obesity and cardiovascular risk; the growing evidence for an intergenerational cycle of obesity; the role of maternal leptin in programming appetite; possible cellular mechanisms for altered energy balance, including mitochondrial programming and the effects of regulators of metabolism; and how epigenetic changes might be the fundamental underlying mechanism explaining programming effects. Consumer understanding of the concept of early nutrition programming and the extent to which early nutrition programming is taken into account in infant feeding policies are also discussed.

This book presents both theoretical contributions and empirical applications of advanced statistical techniques including geo-additive models that link individual measures with area variables to account for spatial correlation; multilevel models that address the issue of clustering within family and household; multi-process models that account for interdependencies over life-course events and non-random utilization of health services; and flexible parametric alternatives to existing intensity models. These analytical techniques are illustrated mainly through modeling maternal and child health in the African context, using data from demographic and health surveys.   In the past, the estimation of levels, trends and differentials in demographic and health outcomes in developing countries was heavily reliant on indirect methods that were devised to suit limited or deficient data. In recent decades, world-wide surveys like the World Fertility Survey and its successor, the Demographic and Health Survey have played an important role in filling the gap in survey data from developing countries. Such modern demographic and health surveys enable investigators to make in-depth analyses that guide policy intervention strategies, and such analyses require the modern and advanced statistical techniques covered in this book.   The text is ideally suited for academics, professionals, and decision makers in the social and health sciences, as well as others with an interest in statistical modelling, demographic and health surveys. Scientists and students in applied statistics, epidemiology, medicine, social and behavioural sciences will find it of value.   

Authored by Bengt Kallen, professor emeritus in embryology at Lund University in Sweden. The subject of this book is to describe the occurrence of congenital malformations among children born and what risk factors exist. Population data are presented for a number of malformations, ascertained with the use of data from the Swedish national health registers for the period 1998-2010 corresponding to some 1.3 million births, together with prospectively collected information on a group of exposures of possible interest. The structure of the analysis is such that it excludes studies of, for instance, nutrition, alcohol or street drug use and many other lifestyle factors where prospective information or independent register information is difficult or impossible to obtain. Epidemiology of Human Congenital Malformations culminates with a discussion on how the presence of malformations can be explained and various possibilities for the prevention of birth defects. Moreover, it will include a series of instructions on how to read epidemiological literature in this field making it an essential resource both for those currently working in the field of reproductive epidemiology or those intending to enter it. It will additionally be useful for doctors working with malformations, either as obstetricians, neonatologists or pediatricians.

This issue of Clinics in Laboratory Medicine, edited by Drs. Anthony Odibo and David A. Krantz, covers issues surrounding Prenatal Screening and Diagnosis. Topics examined in this issue include, but are not limited to: Strategies for Implementing cfDNA Testing; Genetic Counselling for Patients Considering Screening and Diagnosis of Chromosomal Abnormalities; Microdeletions/Duplications; Sex Chromosome Abnormalities; First-, Second- and Third-Trimester Screening for Preeclampsia and Intrauterine Growth Restriction; Biophysicial/Biochemical Screening for the Risk of Preterm Labor; Preimplantation Genetic Testing; Toxoplasmosis, Parvovirus and Cytomegalovirus in Pregnancy; and Sleep Apnea and Adverse pregnancy Outcomes.

Dana S. Belu combines Heidegger's phenomenology of technology with feminist phenomenology in order to make sense of the increased technicization of women's reproductive bodies during conception, pregnancy, and birth.

This stimulating volume addresses vital questions about gene/environment interactions as they affect cell health from the prenatal period through later life. Beginning with a tour of epigenetic processes in the human body, the book assembles current theoretical and empirical developments across the discipline, among them transgenerational epigenetic inheritance, the effects of maternal nutrition on epigenetic change, and possible links between epigenetics and childhood obesity. Public health and policy aspects of the field are discussed in depth, with the understanding that much can be done to improve our epigenetic health as a species. And in this vein, contributors consider future possibilities, such as the reprogramming of genes to reverse cancer and other diseases. Included in the coverage: The role of environmental epigenetics in perinatal and neonatal development The epigenetic biomarker H2AX: from bench science to clinical trials What's the risk? Dental amalgam, mercury exposure, and human health risks throughout the lifespan Post-traumatic stress disorder: neurological, genetic, and epigenetic bases Children's exposure to alcohol, tobacco, and drugs: long-term outcomes Ethical implications of epigenetics Epigenetics, the Environment, and Children's Health Across Lifespans brings real-world knowledge and applications of this increasingly important field to public health practitioners, maternal and child health researchers, and environmental health experts.

This volume provides an overview of the research describing the effects of child maltreatment on mental health, cognitive and social-emotional development. It offers descriptions of selected empirically based treatments (EBTs) written by scholars associated with its development, training, or research on its effectiveness. Each contributor presents the theoretical foundation of the EBT and evidence of its efficacy, describes the treatment process and illustrates this process with a case study of its use with a maltreated child, and discusses possible limitations. Following the chapters describing the interventions, the editors address key issues of the dissemination and implementation of these EBTs. They describe the strategies the selected interventions have used to ensure treatment fidelity in training and dissemination from the perspective of implementation science's core components of implementation. The challenges of implementing EBTs, and the difficulty of fitting protocol to the reality of clinical practice in community mental health settings are also discussed. This volume offers a central source of information for students and practitioners who are seeking effective interventions to address problems associated with child maltreatment.

This book provides a practical, multidisciplinary approach to support a broad range of health professionals, social workers, public health workers and others tasked with providing health and care to young adults. The continuum of life begins with the health and wellness of parents prior to conception, followed by embryonic and fetal development, and continues throughout life. Each person's life stages prepare them for the next and determine their health outcome and wellbeing over time. The text highlights the importance of promoting health throughout the lifespan, the influence of intergenerational health, and the concept of the Developmental Origins of Health and Disease in epigenetic processes and embryology. Authors underscore the importance of advancing health equity and lift up some of the ethical considerations in this work. The authors explore specific interventions in four major categories: Lifestyle, Infections, Nutrition, and Contraception / Pregnancy Planning (LINC). Preconception care is defined by the World Health Organization as the provision of biomedical, behavioural and social health interventions to women and couples before conception. Preconception care includes evidence-based interventions to improve health status, to reduce behaviours, individual and environmental factors that contribute to poor health outcomes. This book offers readers evidence-based guidance regarding fertility awareness and sperm health, genetic counselling and lifestyle assessments, as well as mental wellbeing, alcohol, tobacco and pharmacotherapy, and specialist care for those with chronic conditions, including a review of medications. It also covers relevant infections, including HIV and the Zika virus, as well as different types of environmental and occupational exposure. The book employs a framework focusing on health promotion, the social determinants of health, and the science behind preconception care. Strategies for improving preconception and interconception health, including examples from around the globe, are described in detail.

Managing social relationships for childless couples in pro-natalist societies can be a difficult art to master, and may even become an issue of belonging for both men and women. With ethnographic research gathered from two IVF clinics and in two villages in northwestern Turkey, this book explores infertility and assisted reproductive technologies within a secular Muslim population. Goeknar investigates the experience of infertility through various perspectives, such as the importance of having a child for women, the mediating role of religion, the power dynamics in same-gender relationships, and the impact of manhood ideologies on the decision for - or against - having IVF.

In the later stages of gestation, fetal functions undergo increasing change and development, preparing the fetus for the transition to its postnatal environment. Rapid maturation is witnessed in breathing, swallowing, sensory functions, sleep, and many other processes, with corresponding behavioral changes. By 35 to 40 weeks of gestation, fetuses are capable of living ex utero without support, but it is increasingly appreciated that even infants born at between 35 and 36 weeks can suffer long-term consequences. This book, which complements the author's previous volume on development of normal fetal movements during the first 25 weeks of gestation, discusses in detail the full range of behavioral phenomena observed during the final 15 weeks of gestation, with careful analysis of their mutual relationships. A key feature is the outstanding photographic material, difficult to obtain at this late stage, and the instructive graphs that are also included. The information provided will alert clinicians to deviations from the norm and to physiologic phenomena that can turn pathologic in infants born prematurely.

Multiauthored book dealing comprehensively with the various aspects of imaging of pediatric musculoskeletal trauma. The work is subdivided in three main sections: Overview of lesions; Imaging of traumatic injuries according to body region; typical traumatic injuries of early infancy. The third section includes also legal aspects of child abuse (battered child) and will indicate current international medical-legal guidelines. The didactical approach and the wide-ranging account of the subject makes the book particularly valuable to practitioners from various disciplines, involved in diagnosis and management of trauma of pediatric bone and joint

Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.

An estimated 35 million people worldwide are displaced by conflict, and most of them are women and children. During their time away from their homes and communities, these women and their children are subjected to a horrifying array of misfortune, including privations of every kind, sexual assaults, disease, imprisonment, unwanted pregnancies, severe psychological trauma, and, upon return or resettlement, social disapproval and isolation. Written by the world's leading scholars and practitioners, this unique collection brings these problems - and potential solutions - into sharp focus. Based on extensive field research and a broad knowledge of other studies of the challenges facing women who are forced from their homes and homelands by conflict, this book offers in-depth understanding and problem-solving ideas. Derived from a project to advise U.N. agencies, it speaks to a broad array of students, scholars, NGOs, policymakers, government officials, and international organizations.