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Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology

Herpesvirus DNA - Recent studies on the organization of viral genomes, mRNA transcription, DNA replication, defective DNA, and... Herpesvirus DNA - Recent studies on the organization of viral genomes, mRNA transcription, DNA replication, defective DNA, and viral DNA sequences in transformed cells and bacterial plasmids (Hardcover, 1981 ed.)
Yechiel Becker
R5,858 Discovery Miles 58 580 Ships in 10 - 15 working days

Herpesviruses, classified in the family Herpesviridae, are important human and animal pathogens that can cause primary, latent or recurrent infections and even cancer. The major interest in research on herpesviruses today focuses on understanding the organization of the DNA genome, as well as on characterizing the viral genes in regard to their control and function. Modern techniques have allowed the viral DNA to become a molecular tool in the study of gene function, since it is now possible to implant the DNA into eukaryotic cells. This book contains original studies on the structure and organization of the DNA of human and animal herpes viruses. The various chapters acquaint the reader with the organization of the viral DNA, the mRNA transcripts, the replicative intermediates of the viral DNA, defective DNA genomes and their mode of synthesis, analyses of the viral DNA sequences in transformed cells, and the relationship between the presence of viral DNA fragments in the cancer cells and the transformed state of the cells."

Listeria monocytogenes - Methods and Protocols (Hardcover, 2014 ed.): Kieran Jordan, Edward M. Fox, Martin Wagner Listeria monocytogenes - Methods and Protocols (Hardcover, 2014 ed.)
Kieran Jordan, Edward M. Fox, Martin Wagner
R5,138 Discovery Miles 51 380 Ships in 12 - 19 working days

Listeria monocytogenes is still a major threat to public health. A new book in the Methods in Molecular Biology series, Listeria monocytogenes: Methods and Protocols addresses its titular pathogen with protocols and methodologies used in research to gain a better understanding of Listeria at a molecular level. The topics covered include sampling in order to isolate Listeria, methods for their identification and characterization, methods for gene manipulation and finally, methods for control of the organism. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Vital and authoritative, Listeria monocytogenes: Methods and Protocols aims to contribute to the harmonization of the methods used in the field and will therefore benefit all those interested in Listeria research.

Stress Response in Microbiology (Hardcover, New): Jose M. Requena Stress Response in Microbiology (Hardcover, New)
Jose M. Requena
R5,766 Discovery Miles 57 660 Ships in 10 - 15 working days

To survive adverse and fluctuating conditions, microorganisms possess mechanisms to recognize diverse environmental changes and mount an appropriate response. Microorganisms frequently react simultaneously to a wide variety of stresses, and the various stress response systems interact with each other by a complex of global regulatory networks. Stress response systems can play an important role in the virulence of pathogenic organisms. In this book, expert contributors from around the world summarize the current knowledge on microbial stress response and comprehensively review the recent findings that have greatly advanced the understanding of stress response systems. Each chapter is devoted to a particular organism or group of organisms, including: Gram-negative bacteria * Streptococcus * Neisseria * Listeria monocytogenes * Bacillus cereus * Salmonella * Yersinia * Vibrio * Mycobacterium * mycoplasmas * yeast * Plasmodium falciparum * Toxoplasma gondii * Leishmania * Trypanosoma cruzi * Trypanosoma brucei * Entamoeba histolytica. In addition to providing an up-to-date review of current trends, the book also describes the challenges for future research and provides comprehensive reference sections. It represents a major collection of information and knowledge across a wide range of microorganisms and is highly recommended for anyone interested in stress response, regulatory networks, environmental microbiology, or the pathogenicity of microorganisms.

Viral Infections and Antiviral Therapies (Paperback): Amal Kumar Dhara, Amit Kumar Nayak Viral Infections and Antiviral Therapies (Paperback)
Amal Kumar Dhara, Amit Kumar Nayak
R3,678 Discovery Miles 36 780 Ships in 12 - 19 working days

Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts.

Advances in Microbiology, Infectious Diseases and Public Health - Volume 14 (Hardcover, 1st ed. 2020): Gianfranco Donelli Advances in Microbiology, Infectious Diseases and Public Health - Volume 14 (Hardcover, 1st ed. 2020)
Gianfranco Donelli
R4,359 Discovery Miles 43 590 Ships in 10 - 15 working days

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention. Advances in Microbiology, Infectious Diseases and Public Health is a subseries of Advances in Experimental Medicine and Biology, which has been publishing significant contributions in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. 2018 Impact Factor: 2.126.

Hot Topics in Infection and Immunity in Children VIII (Hardcover, 2011): Nigel Curtis, Adam Finn, Andrew J. Pollard Hot Topics in Infection and Immunity in Children VIII (Hardcover, 2011)
Nigel Curtis, Adam Finn, Andrew J. Pollard
R4,384 Discovery Miles 43 840 Ships in 10 - 15 working days

Book covers course with topics in infectious diseases in children and is intended for Pediatric Infectious disease clinical researchers, trainees, trainers, and all those who manage the research of children with infections and the children themselves. The conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc. ToC reflects the scientific program found here: http: //www.oxfordiic.org/#course

Synthetic Peptide Vaccine Models - Design, Synthesis, Purification and Characterization (Paperback): Mesut Karahan Synthetic Peptide Vaccine Models - Design, Synthesis, Purification and Characterization (Paperback)
Mesut Karahan
R1,557 Discovery Miles 15 570 Ships in 12 - 19 working days

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes - the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

A Modern Approach to Biofilm-Related Orthopaedic Implant Infections - Advances in Microbiology, Infectious Diseases and Public... A Modern Approach to Biofilm-Related Orthopaedic Implant Infections - Advances in Microbiology, Infectious Diseases and Public Health Volume 5 (Hardcover, 1st ed. 2017)
Lorenzo Drago
R4,848 Discovery Miles 48 480 Ships in 12 - 19 working days

This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the potential causes of these infections, provides sound diagnostic criteria guidelines, and explains how these prosthetic infections are managed from orthopedic surgery, clinical and diagnostic perspectives. PJI can lead to multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1-2% after primary total hip and knee arthroplasty and account for approximately 7-12% of all revision cases. Orthopedic hardware infections are much-feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to higher morbidity, it is important to understand their pathophysiology and the principles behind their diagnosis and initial treatment. The pathogenesis of these kinds of infections is intimately connected to the biofilm-producing trait characteristic of many microorganisms, which can have a critical effect on the likely success of treatments. The book offers a unique guide for all scientists working in arthroplasty who are seeking an update on the field, and for newcomers alike.

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease (Hardcover, 2014 ed.): Mark Lyte, John F. Cryan Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease (Hardcover, 2014 ed.)
Mark Lyte, John F. Cryan
R7,631 Discovery Miles 76 310 Ships in 12 - 19 working days

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("us"). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.

Antiviral Chemotherapy 5 - New Directions for Clinical Application and Research (Hardcover, 1999 ed.): John Mills, Paul A.... Antiviral Chemotherapy 5 - New Directions for Clinical Application and Research (Hardcover, 1999 ed.)
John Mills, Paul A. Volberding, Lawrence Corey
R4,587 Discovery Miles 45 870 Ships in 10 - 15 working days

Scientists and clinicians attending the last "New Directions in Antiviral Therapy" conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since. Two new classes of antiretrovirals have been licensed, the second-site RT inhibitors and the protease inhibitors; the long in cubation period of active HIV infection, when the infection is clinically latent, is now un derstood to be a period of intense viral replication and turnover of CD4 lymphocytes; measurements of HI V RNA concentration in plasma have been shown to be essential tools for monitoring the course of HIV infection, deciding when to treat, and assessing the re sults of treatment; and finally, combinations of antiretrovirals, particularly combinations including protease inhibitors, have been shown to have dramatically beneficial effects on patients with HIV infection. These advances, coupled with new drugs for the management of herpesvirus infections, have made dramatic differences in the quality and length of life of HIV-infected patients. Additional advances have been made since 1994 in the prevention or management of influenza virus (zanamavir), respiratory syncytial virus (palvizumab), hepatitis B virus (lamivudine and famciclovir), and enterovirus infections (pleconaril). It is difficult to re member that only slightly more than a decade ago there were only a handful of antiviral agents available (none of which were antiretrovirals), and a number of those were either highly toxic, of dubious efficacy, or both."

Epstein-Barr Virus and Human Cancer (Hardcover): Kenzo Takada Epstein-Barr Virus and Human Cancer (Hardcover)
Kenzo Takada
R2,590 Discovery Miles 25 900 Ships in 12 - 19 working days

In this book, outstanding researchers from the US and Japan review recent progress in Epstein-Barr virus research. Most people carry EBV in memory B-cells in a latent stage. Many malignancies such as T/NK cell lymphoma, AIDS-associated B-cell lymphoma, gastric carcinoma and Hodgkin's disease have been causally linked to EBV. The development of molecular biology technique has allowed us to study the roles of individual EBV genes that act in the maintenance and disruption of EBV latency.

Pathogenicity and Drug Resistance of Human Pathogens - Mechanisms and Novel Approaches (Hardcover, 1st ed. 2019): Saif Hameed,... Pathogenicity and Drug Resistance of Human Pathogens - Mechanisms and Novel Approaches (Hardcover, 1st ed. 2019)
Saif Hameed, Zeeshan Fatima
R5,646 Discovery Miles 56 460 Ships in 10 - 15 working days

The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases. Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases. In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance, therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.

Pertussis Infection and Vaccines - Advances in Microbiology, Infectious Diseases and Public Health Volume 12 (Hardcover, 1st... Pertussis Infection and Vaccines - Advances in Microbiology, Infectious Diseases and Public Health Volume 12 (Hardcover, 1st ed. 2019)
Giorgio Fedele, Clara Maria Ausiello
R2,898 Discovery Miles 28 980 Ships in 10 - 15 working days

This book provides a comprehensive overview of pertussis - also known as whooping cough. The first part discusses the evolution the genus Bordetellae and the molecular epidemiology of B. pertussis, while the following chapters focus on the role of B. pertussis virulence factors in infection and disease and on the mechanisms of the immune response to infection and vaccination. The book also explores the prevention and control of the disease as well as its clinical management, with the finally section addressing vaccination, from improved immunization strategies to novel vaccines. Pertussis remains one of the most poorly controlled vaccine-preventable diseases around the globe. Universal vaccination has dramatically reduced its incidence but has failed to bring it completely under control. In recent decades, changes in pertussis epidemiology have been noted, likely related to the use of acellular pertussis vaccines, which in many countries have replaced older-generation, whole-cell pertussis vaccines. Several years after their introduction, it is becoming apparent that immunity conferred by acellular vaccines wanes more rapidly than expected. Unlike whole-cell vaccines, acellular vaccines, while protecting against the disease, do not seem to prevent colonization and transmission. Increasing incidence among adolescents and adults makes them a reservoir for transmission to unimmunized infants, who in turn are at risk of severe disease and death. This book is a valuable resource for researchers and clinicians in the field of medical microbiology, vaccine research and infectious diseases.

Advances in Applied Microbiology, Volume 97 (Hardcover): Geoffrey Michael Gadd, Sima Sariaslani Advances in Applied Microbiology, Volume 97 (Hardcover)
Geoffrey Michael Gadd, Sima Sariaslani
R3,908 R3,277 Discovery Miles 32 770 Save R631 (16%) Ships in 12 - 19 working days

Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

Advances in Applied Microbiology, Volume 96 (Hardcover): Geoffrey Michael Gadd, Sima Sariaslani Advances in Applied Microbiology, Volume 96 (Hardcover)
Geoffrey Michael Gadd, Sima Sariaslani
R3,263 Discovery Miles 32 630 Ships in 12 - 19 working days

The Advances in Applied Microbiology series, first published in 1959, continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology and includes recent research on the role staphylococcus aureus aggregation and coagulation mechanisms, along with analysis of microbial communities in the deep biosphere.

Host-Microbe Interactions, Volume 142 (Hardcover): Michael San Francisco, Brian San Francisco Host-Microbe Interactions, Volume 142 (Hardcover)
Michael San Francisco, Brian San Francisco
R4,690 R3,931 Discovery Miles 39 310 Save R759 (16%) Ships in 12 - 19 working days

Host-Microbe Interactions, the latest volume in the Progress in Molecular Biology series, provides a forum for the discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their respective fields, along with abundant references. This volume is dedicated to the subject of host-microbe interactions.

The Vaccine Book (Paperback, 2nd edition): Barry R. Bloom, Paul-Henri Lambert The Vaccine Book (Paperback, 2nd edition)
Barry R. Bloom, Paul-Henri Lambert
R2,620 Discovery Miles 26 200 Ships in 12 - 19 working days

The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk.

Statistical Aspects of the Microbiological Examination of Foods (Paperback, 3rd edition): Basil Jarvis Statistical Aspects of the Microbiological Examination of Foods (Paperback, 3rd edition)
Basil Jarvis
R1,786 Discovery Miles 17 860 Ships in 12 - 19 working days

Statistical Aspects of the Microbiological Examination of Foods, Third Edition, updates some important statistical procedures following intensive collaborative work by many experts in microbiology and statistics, and corrects typographic and other errors present in the previous edition. Following a brief introduction to the subject, basic statistical concepts and procedures are described including both theoretical and actual frequency distributions that are associated with the occurrence of microorganisms in foods. This leads into a discussion of the methods for examination of foods and the sources of statistical and practical errors associated with the methods. Such errors are important in understanding the principles of measurement uncertainty as applied to microbiological data and the approaches to determination of uncertainty. The ways in which the concept of statistical process control developed many years ago to improve commercial manufacturing processes can be applied to microbiological examination in the laboratory. This is important in ensuring that laboratory results reflect, as precisely as possible, the microbiological status of manufactured products through the concept and practice of laboratory accreditation and proficiency testing. The use of properly validated standard methods of testing and the verification of 'in house' methods against internationally validated methods is of increasing importance in ensuring that laboratory results are meaningful in relation to development of and compliance with established microbiological criteria for foods. The final chapter of the book reviews the uses of such criteria in relation to the development of and compliance with food safety objectives. Throughout the book the theoretical concepts are illustrated in worked examples using real data obtained in the examination of foods and in research studies concerned with food safety.

Skin Diseases of Cattle in the Tropics - A Guide to Diagnosis and Treatment (Paperback): Mohamed Elamin Hamid Skin Diseases of Cattle in the Tropics - A Guide to Diagnosis and Treatment (Paperback)
Mohamed Elamin Hamid
R928 Discovery Miles 9 280 Ships in 12 - 19 working days

Skin Diseases of Cattle in the Tropics: A Guide to Diagnosis and Treatment is a clinical and practical guide to help animal scientists, field veterinarians, veterinary students, and technicians make appropriate and differential diagnoses. It features quizzes of clinical cases, along with multiple images of characteristic lesions and laboratory findings of major skin diseases (and diseases with skin manifestations) that are prevalent in tropical areas, notably the Sub-Saharan African countries. This self-learning and easy-to-use instructional guide, a unique offering in the field of animal science and veterinary medicine, provides essential and foundational information about relevant skin conditions that are followed by illustrated flow charts of laboratory diagnoses and summaries of respective diseases. This title makes the subject accessible for practicing veterinarians and animal scientists, and is particularly useful for those who have neither seen nor had the chance to see these diseases in the field or clinics. Such diseases are important not only in the tropics, but may be encountered in many countries in subtropical and temperate zones.

Advances in Microbiology, Infectious Diseases and Public Health - Volume 7 (Hardcover, 1st ed. 2017): Gianfranco Donelli Advances in Microbiology, Infectious Diseases and Public Health - Volume 7 (Hardcover, 1st ed. 2017)
Gianfranco Donelli
R4,111 Discovery Miles 41 110 Ships in 10 - 15 working days

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention.

Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems (Hardcover, 1st ed. 2019): Kevin L. Williams Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems (Hardcover, 1st ed. 2019)
Kevin L. Williams
R6,517 Discovery Miles 65 170 Ships in 10 - 15 working days

Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd "living fossil" (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma). Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of "at will" production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated. Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease.

Dahlem LS - The Eradication of Infectious Diseases (about life sciences but no LS no.) (Hardcover): W.R. Dowdle Dahlem LS - The Eradication of Infectious Diseases (about life sciences but no LS no.) (Hardcover)
W.R. Dowdle
R9,335 Discovery Miles 93 350 Ships in 12 - 19 working days

In October, 1987, smallpox became the first disease of humans to have been deliberately eradicated. Since then, global eradication campaigns against dracunculiasis (Guinea worm disease) and poliomyelitis have nearly reached their goals, and initial steps have been taken to stimulate similar programs to eradicate lymphatic filariasis and measles. Other successful efforts are expected to follow these. In 1993, an International Task Force for Disease Eradication evaluated over 80 potential candidate diseases and made recommendations. However, little has been done to develop the science of eradication systematically. This book reports the findings of a multidisciplinary workshop on the eradication of infectious diseases. It reviews the history of eradication efforts and lessons from previous campaigns and distinguishes among eradication, elimination, and control programs and extinction of an etiologic agent. It addresses a wide range of related issues, including biological and socio-political criteria for eradication, costs and benefits of eradication campaigns, opportunities for strengthening primary health care in the course of eradication efforts, and other aspects of planning and implementing eradication programs. Finally, it stresses the importance of global mechanisms for formulating and implementing such programs. Goal of this Dahlem Workshop: to identify the biological/epidemiological, cost/benefit, and societal/political criteria for the eradication of infectious diseases.

Ebola Virus Disease - From Origin to Outbreak (Paperback): Adnan I Qureshi Ebola Virus Disease - From Origin to Outbreak (Paperback)
Adnan I Qureshi; Contributions by Omar Saeed
R2,487 R2,280 Discovery Miles 22 800 Save R207 (8%) Ships in 12 - 19 working days

Ebola Virus Disease: From Origins to Outbreak covers Ebola virus disease in its entirety from its origins through major outbreaks in the past to the present day outbreak. It contains information on the West Saharan response to Ebola as well as highlights from the field in West Africa from Dr. Qureshi and Dr. Chughtai, helping to solve the primary question of what's next and aiding in formulating a path forward. With a growing awareness of the devastating effects of this viral disease and an influx of topical research, this book provides the information the global community of researchers, clinicians and students need to better inform their research and study of Ebola virus disease.

Arenaviruses, v.2 - The Molecular Pathogenesis of Arenavirus Infections (Hardcover, illustrated edition): Michael B.A. Oldstone Arenaviruses, v.2 - The Molecular Pathogenesis of Arenavirus Infections (Hardcover, illustrated edition)
Michael B.A. Oldstone
R2,592 Discovery Miles 25 920 Ships in 12 - 19 working days

The second volume of Arenaviruses deals with the biology and the pathogenesis of arenaviruses primarily through the study of LCMV. Interestingly and appropriately, the fundamental observation of MHC restriction and CD8 cytotoxic T lymphocyte killing derived initially from studies with LCMV in the mouse has been expanded to studies of most human pathogens, viral, bacterial, parasitic, as well as events in cancer. The scope and importance of this observation was recognized by awarding the Nobel Prize in 1996 to Rolf Zinkernagel and Peter Doherty, long-time workers in the field of LCMV and arenavirus biology. Over the last 14 years many of the principles for understanding viral pathogenesis and biology of animal viruses have been defined, in great part from the lessons learned by studying LCMV. Those lessons and their implications are the subject of this second volume on the arenaviruses.

Moonlighting Cell Stress Proteins in Microbial Infections (Hardcover, 2013 ed.): Brian Henderson Moonlighting Cell Stress Proteins in Microbial Infections (Hardcover, 2013 ed.)
Brian Henderson
R5,535 R5,188 Discovery Miles 51 880 Save R347 (6%) Ships in 12 - 19 working days

Microbial infection is increasingly seen as a problem as we begin to run out of antibiotics. Understanding how microbes cause disease is essential. In recent years it has begun to emerge that bacteria, fungi, protozoa and viruses can use their cell stress proteins to cause infection. This volume brings together the world's leading experts in the study of the microbial and human cell stress proteins that are involved in enabling microorganisms to infect humans and cause serious disease.

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