There has been emergence of multidrug resistance problem all over
the world due to overuse or underuse of antibiotics. Most microbes
including bacteria, fungi, protozoans and others have developed
resistance to antibiotics, and therefore, this problem is now
recognized to be of global concern. Ubiquitous occurrence of
multidrug-resistant bacteria decreases effectiveness of current
treatment, which results in thousands of deaths all over the world.
Hence, investigations for new alternatives and novel strategies are
urgently needed to address the problem of multidrug resistance. The
antimicrobial potential of essential oils and metallic
nanoparticles represent an effective solution for microbial
resistance. Moreover, the use of essential oils in combination with
metallic nanoparticles may exert synergistic antimicrobial effects
and would be a novel approach. Essential oils (EOs) are volatile,
natural, aromatic oily liquids that can be obtained from several
parts of plants especially the aerial ones such as leaves and
flowers. They are derived from complex metabolic pathways in order
to protect plants from diverse pathogenic microorganisms. In fact,
the bioactivity of EOs have been confirmed by several studies which
have demonstrated their antibacterial, antiviral,
anti-inflammatory, antifungal, antimutagenic, anticarcinogenic, and
antioxidant properties. Nanotechnology is one of the most important
and emerging technologies, which has brought about a technological
revolution in the world. It has enormous applications in the field
of medicine. Nanoparticles are very important tools in curing
different diseases in general and microbial diseases in particular
due to their significantly novel and improved chemical, physical
and biological properties and high surface area-to-volume ratio.
Among these, metal nanoparticles are known to play pivotal role in
various biomedical applications. In this context, nanoparticles
such as silver have shown their potential and could emerge as the
new generation of antimicrobials. Silver nanoparticles have
broad-spectrum biological activities and hence are used in many
biomedical applications. The various biomedical applications of
silver nanoparticles include treatment of wounds, burns, in
water-disinfecting systems, in nanobased bone implantations, in
dentistry for the development of dental materials and as
antibacterial, antivirals, anti-protozoals, anti-arthropods and
anticancerous agents. Apart from silver, noble metal nanoparticles
like gold and platinum and other nanoparticles copper, oxides of
different metals, etc. have been also the materials of choice for
many scientists for their biological applications. The book will be
of interest to chemists, microbiologists, biotechnologist, food
technologists, nanotechnologists, pharmacologists, clinicians and
those interested in nature cure. Students will find this book
useful and reader friendly.
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