This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been involved in a serious accident with neurological consequences or have been diagnosed with a severe neurological illness. It covers the full range of disorders of the central and the peripheral nervous system, not only providing very accurate prognostic estimates but also addressing relevant clinical issues, differential diagnosis, and the role of imaging. The book is practically oriented and designed for use on a daily basis when assessing prognosis and discussing the outcome with patients, their families, and other interested parties. It will support patient-doctor partnerships by ensuring that the most professional answers can be given to patients' and doctors' questions and by promoting realistic expectations of the effect of medical interventions. In addition, it will enable doctors, lawyers, and other professionals to understand relevant issues when an estimate of prognosis and life expectancy is the subject of legal dispute.

This book is written for the clinician, students, and practitioners of neuropsychology, neuropsychiatry, and behavioral neurology. It has been my intent throughout to present a synthesis of ideas and research findings. I have reviewed thousands of articles and research reports and have drawn extensively from diverse sources in philosophy, psychol ogy, neurology, neurosurgery, neuropsychiatry, physiology, and neuroanatomy in order to produce this text. Of course I have also drawn from my own experience as a clinician and research scientist in preparing this work and in this regard some of my own biases and interests are represented. I have long sought to understand the human mind and the phenomena we experience as conscious awareness. After many years of studying a variety of Western and Eastern psychologists and philosophers, including the Buddhist, Taoist, and Hindu philosophical systems, I began, while still an undergraduate student, to formulate my own theory of the mind. I felt, though, that what I had come upon were only pieces of half the puzzle. What I knew of the brain was minimal. Indeed, it came as quite a surprise when one day I came across the journal Brain as I was browsing through the periodicals section of the library. I was awed. An entire journal devoted to the brain was quite a revelation. Nevertheless, although intrigued by the possibilities, I resisted."

Surgical pathology is the cornerstone in the management of neoplastic disorders. Written for the practicing surgical pathologist in mind, Surgical Pathology of Endocrine and Neuroendocrine Tumors provides an up-to-date text on surgical pathology of endocrine and neuroendocrine tumors. The text begins with radiological imaging of tumors, followed by a section on fine needle aspiration biopsy. The main section focuses on surgical pathology of endocrine and neuroendocrine tumors. The volume closes with applications of molecular techniques and their potential for the future. Surgical Pathology of Endocrine and Neuroendocrine Tumors is written by a panel of internationally recognized pathologists who are not only experts in their fields, but who also contribute their own valuable insights making this new book an essential resource for practicing general and specialist surgical pathologists and pathologists in training.

Long awaited, this fine surgical atlas covers all aspects of neuro-otology and lateral skull base procedures in comprehensively in detail. The lavishly illustrated step-by-step guide is written by two American experts to ensure continuity between topics. The text is highly structured with step-by-step explanation of each surgical procedure and TIPS and TECHNIQUES sections as well as a PEARLS section in each chapter. More than 200 superb artwork illustrations describe each surgical procedure with nearly 600 additional intraoperative pictures with CT and MRI images to teach specific case examples. This offers a complete educational experience for the skull base surgeon in training and a thorough reference for the experienced surgeon.

As a result of the increasing number of surgical procedures on the brain, head, neck, and spine, postoperative changes are being encountered more frequently on neuroradiological examinations. However, these findings are often unfamiliar to neuroradiologists and neurosurgeons and can be difficult to interpret. This book, which contains numerous images and to-the-point case descriptions, is a comprehensive yet concise reference guide to postsurgical neuroradiology. It will enable the reader to identify the type of surgery performed and the hardware implanted and to differentiate expected sequelae from complications. Topics reviewed include trauma, tumors, vascular disorders, and infections of the head, neck, and spine; cerebrospinal fluid abnormalities; and degenerative diseases of the spine. This book will serve as a unique and convenient resource for both neuroradiologists and neurosurgeons.

In this book, leading international specialists in the field join forces to discuss topics, issues and approaches that are of key importance in the optimal treatment of lumbar degenerative disk disease. The coverage is wide ranging, from current understanding of physiopathology and genetics and modern imaging techniques through to the diverse minimally invasive, non-fusion, and fusion surgical techniques. Detailed attention is drawn to the most important aspects to be considered when approaching the patient and making treatment decisions. The role of conservative management is appraised, and surgical techniques and their indications are carefully described. In the concluding section, some of the top specialists from across the world reflect on the lessons that they have learned during lifetimes in spinal surgery. Advanced Concepts in Lumbar Degenerative Disk Disease will be an instructive and fascinating source of information for all spine surgeons and other spine care providers.

Survey.- Cavum Nasi and Fossa Pterygopalatina.- Sinus Sphenoidalis and Fossa Pterygopalatina.- Tuba Auditiva (Eustachii).- Pyramis (Petrous Bone, Pars Petrosa Plus Pars Tympanica).- Clivus Area and Pars Condylaris.- Special Surgical Aspects Examples.

This concise digest offers a practically oriented and up-to-date overview of all subjects in pediatric surgery according to the European surgical curriculum. Additionally, interdisciplinary aspects concerning pediatrics, adult surgery, obstetrics and other disciplines working with children are considered. The tables enable quick access to indications for the operative and conservative therapy with schematic step-by-step illustrations for nearly all surgical procedures.

Computer-assisted techniques in the surgery of the facial skeleton including the skull base are depicted for the very first time in this atlas of navigational surgery. Experienced surgeons as well as trainees will benefit from the detailed and well-illustrated information on the use of computer technology in clinical routine, accompanied by the experimental basis of intraoperative accuracy. New methods of non-invasive referencing and the use of virtual models in the field of oral and cranio-maxillofacial surgery are demonstrated. Clinical cases illustrate the practical use of this new technique.

This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.

Nearly 80 short papers originating from the 14th International Symposium on Intracranial Pressure and Brain Monitoring held in Tuebingen, Germany, in September 2010 present experimental as well as clinical research data related to the naming topics of the conference. The papers have undergone a peer-reviewing and are organized in the following sections: methods of brain monitoring and data analysis, methods of invasive and non-invasive ICP assessment, the role of autoregulation, the role of tissue oxygenation and near-infrared spectroscopy, hydrocephalus/IIH imaging and diagnosis, management and therapy of hydrocephalus, management and therapy of traumatic brain injury, management and therapy of subarachnoid and intracranial hemorrhage, experimental approaches to acute brain disease. The book gives a good overview on the latest research developments in the field of ICP and related brain monitoring and on management and therapy of relevant acute brain diseases.

This concise reference clarifies the gray areas between traumatic brain injury and PTSD while providing an empirically sound framework for neuropsychological evaluation and differential diagnosis. Its extended research review summarizes findings on key topics including the neuroanatomy of brain injury, test battery design and selection, and the salience of accurate diagnosis to ensuring appropriate specialized treatment. The authors offer the possibility of combined diagnosis as well as injuries that may fall through the diagnostic cracks, and consider possible relationships between TBI, PTSD, and the dementias, including Alzheimer's disease. This knowledge base and the practical guidelines it informs are presented so that readers can better: * Understand the clinical distinctions between TBI and PTSD, and among forms of TBI. * Recognize cognitive, behavioral, emotional, and social components of the disorders. * Identify skill areas for neuropsychological evaluation of patients. * Select appropriate instruments for individualized assessment.* Address test administration and interpretation concerns. * Make an accurate differential diagnosis between PTSD and TBI. With its sharp focus on the nuances of trauma and recovery, The Intercorrelation of Traumatic Brain Injury and PTSD in Neuropsychological Evaluations will find a wide, interested audience among psychologists, neuropsychologists, neurologists, psychiatrists, social workers, mental health counselors, undergraduate and graduate level students, and researchers. In addition, this text may be useful for those interested in psychology and neurology. <

Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference. Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.

Once feared and misunderstood even among the medical community, epilepsy has since largely been demystified. Besides the characteristic seizures, various cognitive, behavioral, and emotional difficulties are recognized as associated with the condition, and patients are finding relief in medical management and/or surgical intervention. Not surprisingly, neuropsychology has emerged as a major component in treatment planning, program development, and assessment of surgical candidates. Geared toward beginning as well as veteran clinicians, the Handbook on the Neuropsychology of Epilepsy offers readers a skills-based framework for assessment and treatment, using current evidence and standardized terminology. Expert coverage reviews widely-used methods for evaluating key aspects of patient functioning (MRI, MEG, electrocortical mapping, the Wada test), and presents guidelines for psychotherapeutic and cognitive remediation strategies in treating comorbid psychiatric conditions. Given the diversity of the patient population, additional chapters spotlight issues specific to subgroups including high- and low-functioning as well as geriatric and pediatric patients. This integrative hands-on approach benefits a range of practitioners across medical and neurological settings. Topics featured in the Handbook: Neuropsychological assessment across the lifespan. Evaluating the epilepsy surgical candidate: methods and procedures. The Wada test: current perspectives and applications. Assessing psychiatric and personality disorders in the epilepsy patient. Evaluation and management of psychogenic non-epileptic attacks. Neuropsychological assessment with culturally diverse patients. Practical and flexible in its coverage, the Handbook on the Neuropsychology of Epilepsy serves not only neuropsychologists and neurologists but also primary care physicians such as internists, family physicians, and pediatricians.

This book provides up-to-date, practical information on functional mapping in order to assist neurosurgeons responsible for safely removing lesions in and around eloquent cortex - one of the greatest challenges in neurosurgery. The roles of pre- and intraoperative mapping techniques are clearly explained, highlighting the advantages and limitations of each tool available to the neurosurgeon. The inclusion of treatment algorithms for applications in specific clinical circumstances ensures that the book will serve as a clear guide to this most complex of neurosurgical problems. To further assist the reader, instructive clinical case examples, accompanied by intraoperative photos and other illustrative material, help to explain the applications of functional mapping of eloquent cortex in different pathologies. Practitioners will find the book to be a ready guide to navigation of the practical decisions commonly faced when operating in eloquent cortex.

The book provides an authoritative source of knowledge about these problematic disorders. It bridges the gap between clinical recognition and the new molecular medicine. The editors, distinguished clinicians and geneticists, assembled an internationally renowned group of collaborators, many of them the experts who first described a particular disorder or established its present accepted definition. They have written a practical, comprehensive guide to the recognition, investigation and management of more than 60 recognised phakomatoses.

Accurate interpretation of indications for treatment is the cornerstone of success in medicine. This book carefully examines the relation between clinical features, diagnosis, and choice of minimally invasive technique for a range of spine pathologies. It explains how selection of technique is intimately related to clinical and diagnostic aspects and how recognition of this relation forms the foundation for an optimal outcome. In addition to examining the various minimally invasive options, including the latest techniques, careful attention is paid to the role of medical treatment in avoiding recurrence after initial therapy. Nerve blocks, epidural injections, and intradiscal procedures are among the many options available in the armamentarium of the interventionalist, and advice is given on their use in different contexts. This volume will be of great value for neuroradiologists and others responsible for treating patients with spine disorders.

Addressing all aspects of brain death and thoroughly detailing how a potential organ donor should be maintained to ensure maximum use of the organs and cells, The Brain-Dead Organ Donor: Pathophysiology and Management is a landmark addition to the literature. This first-of-its-kind, multidisciplinary volume will be of interest to a large section of the medical community. The first section of the book reviews the historical, medical, legal, and ethical aspects of brain death. That is followed by two chapters on the pathophysiology of brain death as investigated in small and large animal models. This includes a review of the many hormonal changes, including the neuroendocrine- adrenergic 'storm', that takes place during and following the induction of brain death, and how they impact metabolism. The next section of the book reviews various effects of brain death, namely its impact on thyroid function, the inflammatory response that develops, and those relating to innate immunity. The chapters relating to assessment and management of potential organ donors will be of interest to a very large group of transplant surgeons and physicians as well as critical care and neurocritical care physicians and nurses. Neurologists, endocrinologists, neurosurgeons, and pathologists will also be interested, especially in the more basic science sections on various aspects of brain-death and hormonal therapy. Organ procurement organizations and transplant coordinators worldwide will also be interested in this title. Other chapters will be of interest to medical historians, medico-legal experts, and ethicists.

The third edition of this classic text again provides practical, comprehensive coverage of the anatomical and physiological basis for intraoperative neurophysiological monitoring. Written by a leading authority in the field, Dr. Aage Moller has updated this important title to again offer all the leading-edge knowledge needed to perform electrophysiological recordings in the operating room, to interpret the results, and to present the results to the surgeon. The field known as "intraoperative monitoring" has expanded rapidly to cover other uses of neurophysiology and electrophysiologic recordings during surgical operations that affect the brain, spinal cord, and other parts of the nervous system. These new areas are covered in this new edition. To better represent the content of the book and the field as it now stands, many of the chapters have been revised and new material has been added. While the general organization of the book is maintained, chapters such as monitoring of motor systems have been revised and extended with new material, including more detailed description of the anatomy and physiology of motor systems and new information about intraoperative monitoring.

The contributions in this volume, presented at the 5th International Hydrocephalus Workshop in May 2010 in Crete, Greece, give the present state-of-the-art in timely diagnosis and treatment of hydrocephalus. The topics covered include advances in management of both pediatric and adult hydrocephalus, identifying shunt responders, clinical experiences in endoscopic third ventriculostomy, clinical trials, pathophysiology, experimental studies, and the new classification for hydrocephalus.

The second edition of The Growing Spine has been extensively revised to cover recent advances in knowledge and management. The book is intended as a comprehensive, one-stop reference for specialists and health professionals who care for young children with spinal deformities. In addition, it will effectively help to standardize the care of these patients. Depending on the etiology, children with spinal deformities are often cared for by multiple specialists, including pediatricians, pediatric orthopaedists or orthopaedic spine surgeons, neurologists, pediatric surgeons, pediatric neurosurgeons, oncologists, and pulmonologists. The multidisciplinary nature of care is reflected in The Growing Spine, which will be of value for all involved practitioners rather than just orthopaedic specialists. It will also be an ideal reference for nurses, physical therapists, and healthcare professionals in training, who are usually unfamiliar with spinal deformities in children.

Brain imaging and neurophysiological methods have been rapidly developed. The purpose of this book is to describe hearing problems which are caused by various kinds of brain diseases in central auditory pathway. Each topic is explained to use a lot of figures such as brain imaging and neurophysiological data comparing with neuropsychological tests. Readers will understand what happens in patients, when bilateral auditory nerve and auditory cortex are damaged in patients. Some patients can hear but cannot discriminate meanings of speech, music and environmental sounds. The author tries to explain why such a difference occurs.

More than 60 papers written by internationally recognized experts cover the broad spectrum of brain edema. The main topics treated are: ischemia & hemorrhage, trauma (experimental and clinical), cerebral hemorrhage, tumor, hydrocephlaus & intracranial pressure (ICP), neuromonitoring & neuroimaging, treatments, blood brain barrier, and miscellaneous.

MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

The articles in this volume cover the various options of the optimal management of brain tumors, vascular lesions, and functional disorders. They provide a good balance between microneurosurgery and radiosurgery, presenting also alternative surgical and radiosurgical treatment options with discussions on their advantages and disadvantages. The presentation of multiple treatment methods will help to provide better service to patients. Some papers, specifically highlighting alternative treatment options, are accompanied by editorials prepared by recognized experts in the field. Additional emphasis is put on importance of the advanced neuroimaging techniques for radiosurgical treatment planning and subsequent follow-up.