Guest Edited by experts Paul Nyquist, Neeraj Naval, and Rafael Tamargo of Johns Hopkins, this issue covers a wide range of topics related to Aneurysmal Subarachnoid Hemorrhage, including epidemiology, surgical management, endovascular treatment, non-invasive imaging techniques, risk factors and medical management of vasospasm, cerebral salt wasting, outcomes and costs, medical complications, and more.

Spinal cord injuries typically strike young, previously healthy persons, and leaves the individual with a severe, life-lasting impairment affecting all organ systems. Without adequate management, the risk of severe morbidity and mortality is very high. In contrast state-of-the-art management makes it possible for most persons with SCI to lead long, fulfilling, and autonomous lives despite neurological impairment. This book covers all medical and surgical aspects of modern SCI management from the scene of the accident through rehabilitation to the life-long follow up.

Dr. Paul Klimo, a Neurosurgeon with the Wright-Patterson Medical Center at the Wright-Patterson United States Air Force Base in Ohio guest edits this informative issue on pediatric vascular neurosurgery.? Dr. Klimo and his contributors cover numerous key topics, including normal and abnormal development of the intracranial vascular system, congenital and inherited pediatric neurovascular diseases, diagnosis and management of arteriovenous malformations in children, radiosurgery for pediatric arteriovenous malformations, neurointerventional techniques in children, intracranial cavernous malformations in children, spinal vascular malformations in children, and many more.

For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy.? The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.

Vascular Anatomy: The Head, Neck and Skull Base; Neurovascular Anatomy of the Brain and Skull; Vascular Anatomy of the Spine and Spinal Cord; Intracranial Collateral Anastomoses - Relevance to Endovascular Procedures; CT Imaging, MR Imaging and Ultrasound; Applications to Endovascular Procedures; Techniques and Devices in Neuroendovascular Procedures; Percutaneous Vertebroplasty; Inferior Petrosal Sinus Sampling in the Diagnosis of Sellar Neuropathology; Physiological Testing; Balloon Occlusion Testing, and WADA Testing in Neuroendovascular Procedures

This issue is the last of a two-part series dedicated to Neuroendovasular Management and Guest Edited by Robert Rosenwasser and Pascal Jabbour of Jefferson. Part two covers topics such as Neuroendovascular Management of Carotid Cavernous Fistulae, Endovascular Management of Intracranial Aneurysms, Neuroendovascular Management of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage, Neuroendovascular Management of Acute Ischemic Stroke, and many more.

For this issue, Drs. Daniel Lim and Paul Larson at the University of California San Francisco present a collection of papers dedicated to Functional Neurosurgery. They explore topics such as functional neurosurgery orginis of Intraoperative MRI, iMRI safety, anethesia in the iMRI environment, gene therapy, the use of iMRI for cell-based therapy of Parkinson's desease, and more.

A unique perspective on neuroendoscopic versus microsurgical techniques from world-renowned neurosurgeons In the last two decades, neuroendoscopy has evolved from a fringe neurosurgical tool to an established subspecialty focusing on the treatment of diverse cranial and spinal diseases. Today, neuroendoscopic technology is widely used to treat supratentorial diseases, skull base pathologies, craniocervical diseases, and spinal pathologies. Despite the expanded use of neuroendoscopy across several subspecialties, its benefits and disadvantages versus those of traditional microsurgical methods remain highly controversial. Contradictory evidence in the neurosurgical literature adds to the surgical decision-making challenges for veteran and novice practitioners alike. Controversies in Neuroendoscopy by Peter Nakaji and Hasan Zaidi fills an unmet need for a book encompassing best practices, patient selection, and limitations and advantages of neuroendoscopic surgical approaches. Each case presents firsthand knowledge of internationally esteemed neurosurgeons, with a moderator, an endoscopic expert, and an expert in traditional microsurgical approaches. The unique discussion of neuroendoscopy versus microsurgery enables readers to compare the benefits and pitfalls of endoscopic and open microsurgical procedures for a wide range of conditions. In-depth comparative guidance on applications of the flexible endoscope, rigid endoscope, 3D endoscope, and high-definition 2D endoscope versus the microscope A full spectrum of neurological conditions across the age continuum with comparative approaches for skull base surgery, pituitary surgery, hydrocephalus, spinal surgery, peripheral nerve surgery, and arachnoid cyst fenestration Radiological imaging and intraoperative photographs enhance cases and provide precise, insightful technical guidance High-quality color illustrations from the skilled medical illustrators at Barrow Neurological Institute reinforce key points and surgical techniques Neurosurgery residents, neurosurgeons, and spine surgeons will all benefit from reading this remarkable book cover to cover, and they will no doubt use it as a go-to resource for specific cases. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book provides a modern and up to date overview of the evaluation and management of sports-related neuro trauma. The primary target audience is the "sports neurosurgeon," who can be found on the sidelines of collision sports at all levels of play from high school to professional, or who may care for these athletes in the acute setting in hospital or the outpatient clinics. The reach of this book, however, will also extend to professionals in other fields of medicine due to some topics that extend outside the typical neurosurgical specialty, ranging from chiropractic care in the evaluation and treatment of elite athletes to alternative medical therapies for concussion. The importance of the emerging "sports neurosurgeon" subspecialty is exemplified by the adoption of a policy by the National Football League to require an Unaffiliated Neurotrauma Consultant on-field for player safety. This policy also speaks to the recent public awareness of the importance of recognizing and treating sports-related neuro trauma. This text aims to capitalize on this trend and become a multi-specialty reference to anyone interested in the field. Neurosurgical Care of Athletes serves as a comprehensive resource for physicians and researchers involved in sports-related neuro trauma. All chapters are prepared by experts in their fields and include the most up to date scientific and clinical information.

The new edition of this indispensable reference features the clinical experience of seasoned experts coupled with fresh perspectives from five new authors, providing you with well-rounded, up-to-date coverage on treating all aspects of nerve injuries. Abundant case studies, descriptive examples of major peripheral nerve injuries and other lesions, and outcome analyses help you implement the most appropriate treatment plan for each individual patient. Plus, the all new full-color design throughout offers exceptional visual guidance on surgical techniques. Proved approaches to the surgical treatment of major peripheral nerve injuries, entrapments, and tumors of both the upper and lower extremities make it easy to understand and perform every procedure. In-depth outcome analyses-based on case studies-and discussions on how the available outcome data affect management help you determine the best treatment protocols. New chapters on Iatrogenic Nerve Injuries and Anesthetic and Positional Palsies keep you current. Expanded coverage on suprascapular nerve injury and entrapment, as well as many other essential updates put the latest knowledge at your disposal. Five new authors, well-trained in the field, offer you fresh perspectives. Step-by-step surgical techniques now in full color illuminate every detail.

This concise text mirrors the content of the Epilepsy Board as distributed by the American Board of Psychiatry and Neurology. Epilepsy diagnosis, classification and treatment are thoroughly covered, along with seizure classification, epidemiology, normal and abnormal EEG, and treatment with antiepileptic medications and other modalities. Formatted with multiple choice questions and explanations, this complete resource will prepare physicians and students for the Epilepsy Board examination and provide the latest clinical approaches.

A multidisciplinary guide to managing incidental findings in neuroimaging from top experts Incidental Findings in Neuroimaging and Their Management: A Guide for Radiologists, Neurosurgeons, and Neurologists presents a streamlined, case-based approach to 50 commonly seen incidental findings in neuroimaging. Edited by Kaye Westmark, Dong Kim, and Roy Riascos, this unique book provides the necessary knowledge to manage significant unexpected findings-from identification and analysis to efficacious interventions. With collaborative contributions from neuroradiologists, neurosurgeons, neurologists, otolaryngologists, body and musculoskeletal imaging experts, endocrinologists and hematologists/oncologists, this resource encompasses a wide spectrum of incidental findings. Organized by six sections, the book starts with normal variants that are extremely important to recognize in order to avoid unwarranted additional testing and unnecessary stress for the patient. Subsequent sections detail abnormalities that require extensive clinical evaluation in order to determine ideal management. These include incidental findings for extracranial, extra-spinal, intracranial, and intraspinal imaging. The final section outlines CT and MR imaging artifacts that are particularly concerning because they may mimic more dangerous pathologies while degrading imaging quality and obscuring real findings. Key Features Key findings and differential diagnosis are listed for each entity Diagnostic decision trees present algorithms in an easy-to-understand manner Artifact analyses explain the technical reason for each artifact and what can be done to mitigate effects Clinical Q&As connect the radiologic diagnosis with actual case management decisions and provide in-depth background information that is applicable to management in various scenarios This essential guide will help trainee and practicing neuroradiologists, neurosurgeons, and neurologists interpret incidental spine and brain imaging findings and make clinically informed, complex treatment decisions. This book includes complimentary access to a digital copy on https://medone.thieme.com.

The brain has a remarkable ability to adapt in the event of damage - in many cases shifting responsibility for specific cognitive functions to other non-damaged brain regions. This 'plasticity' can be crucial in aiding recovery from stroke, trauma, and peripheral damage such as eye or ear damage. Over the past thirty years our view of cortical plasticity has evolved greatly. Early studies suggested that changes to cortical function due to peripheral lesions could only occur during development and that these plastic changes were specific to a particular temporal window or "critical period". Over time, it has been demonstrated that cortical modifications as a consequence of either peripheral or central lesions can induce adaptive, or beneficial, changes in cortical function in an effort to preserve or enhance function. More recently, studies have identified that many of these adaptive changes, once thought only possible in the developing brain, are also possible in the mature or developed brain. At present, many laboratories are defining the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeutic strategies may be developed in order to maximiSe the "reprogramming" capabilities of the cerebrum. 'Reprogramming the Cerebral Cortex' describes these exciting studies and examines adaptive cortical plasticity in a variety of systems (visual, auditory, somatomotor, cross-modal, language and cognition). The book leads the reader through the complexities and promise of neuroplasticity, and presents insights into current and future research and clinical practice. It is unique in looking at the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeutic strategies may be developed. The book will be a valuable resource for behavioural, systems, computational and cognitive neuroscientists, as well as clinicians and neuropsychologists.

This unique title is designed to illustrate and foster how a closer working relationship between pediatricians and subspecialists can make childhood medicine work more seamlessly. Despite the common lack of training for pediatricians in pediatric neurosurgery, they are challenged almost daily with caring for children with neurologic conditions. Common Neurological Conditions in the Pediatric Practice is replete with a wide range of instructional case vignettes and is organized into sections that loosely approximate the neurologic development of a child and address issues that are commonly encountered. The first section reviews neurologic development and birth related trauma commonly seen in the neonatal intensive care unit. The second part addresses findings commonly encountered by a pediatrician in a child's first month of life. The third section is a comprehensive review of hydrocephalus. Part four describes state of the art imaging techniques for the central nervous system in children, from pre-natal ultrasound through MRI and CT; and the fifth part consists of individual explorations of common neurosurgical conditions that many pediatricians are uncomfortable managing, including brain tumors, spasticity, and vascular lesions to use as a reference tool when caring for a complex neurosurgical patient. Finally a series of chapters related to head trauma, including sections on non-accidental trauma and concussion management, completes the text.

This book illustrates the characteristics of imaging after treatment in brain gliomas. It describes in detail the modifications to brain tissue, both healthy and pathological, that can manifest after surgery, radiotherapy or chemotherapy treatment. These modifications are discussed in terms of both how they occur in the immediate post-treatment period, and in the long term. The imaging methods used include CT with and without the addition of contrast medium, but above all MRI, which involves the use of routine basic sequences and mainly advanced study techniques such as diffusion, perfusion, spectroscopy and cortical activation. The aim of the text is to equip neuroradiologists with adequate expertise in post-treatment examinations reporting, allowing them to perform an effective differential diagnosis between the persistency or recurrence of illness and the effects of short or long-term treatment. The book is divided into a general section, which addresses the classification of cerebral tumors, the surgical treatment options, radiotherapy and chemotherapy protocols; and a section on clinical cases that employs rich iconography, making it quick and easy to consult. This second edition has been updated to reflect the new WHO classification system from 2016; new surgical, radiotherapy and chemotherapeutic treatment options; and (in the iconography section) the new sequences available from the manufacturers of RM scanners.

Part of the Neurosurgery by Example series, this volume on pediatric neurosurgery presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. As pediatric neurosurgery approximates the anatomical and pathophysiological breadth of all specialty areas of adult neurosurgery, the cases provided are exemplary of those that are more relevant to, and seen in higher frequency, in pediatrics. The cases also demonstrate presentation and management appropriate for pediatrics, as both are distinct in pediatric compared to adult neurosurgery. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Pediatric Neurosurgery is appropriate for neurosurgeons who wish to learn more about a subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

This book on spinal restabilization techniques is an anatomical, biomechanical, clinical, radiological, and surgical overview of the diagnostic methods and newest treatment options for use in patients presenting with degenerative disc disease associated with spinal instability. Edited by a Neurosurgeon and a Neuroradiologist with extensive experience in these areas, it covers the most current information in the field of modern spinal corrective surgery. The varied therapeutic options are presented by many of the primary inventors and first users of the wide array of newly developed and individually unique intersegmental stabilization devices, interbody disc fusion appliances and intervertebral disc replacement implants. This international collection of chapters is intended to be of interest not only to spine surgeons, but also to any physician involved in the diagnosis and treatment of degenerative disc disease and spinal instability that is resistant to conservative management.

Die 3., grundlich uberarbeitete Auflage vermittelt Neurologen, aber auch AErzten anderer Fachgebiete die therapeutischen Grundlagen neurologischer Erkrankungen. Alle in der Klinik oder Praxis bewahrten Therapiemassnahmen werden unter Berucksichtigung der pathogenetischen und klinischen Grundlagen besprochen. Allgemeintherapeutische und spezielle Therapieverfahren sind ebenso dargestellt wie die medikamentoesen Details fur die Bereiche Neurologische Intensivmedizin, Neuropsychiatrie oder Rehabilitation.

Das Essential gibt eine systematische UEbersicht zur Diagnostik und Therapie des Karpaltunnelsyndroms (KTS), des mit Abstand haufigsten Kompressionssyndroms eines peripheren Nervs. Fuhrendes Symptom ist das "Einschlafen" der Hande. Wenn die konservative Behandlung, vorzugsweise mit nachtlicher Ruhigstellung des Handgelenks auf einer Schiene, nicht zu anhaltender Beschwerdefreiheit fuhrt, ergibt sich die Indikation fur eine offene oder endoskopische Retinakulumspaltung. Die diagnostischen Techniken und die Behandlungsmoeglichkeiten werden kritisch und leitlinienkonform diskutiert und eingehend beschrieben. Auf moegliche Risiken und Komplikationen sowie das Vorgehen bei Schwangeren, bei Dialysepatienten u.a. sowie die Tendovaginosis stenosans als wichtigste Begleiterkrankung wird gesondert eingegangen.

This extensively revised edition is an essential reference for physicians involved in the diagnosis, referral and treatment of the thoracic outlet syndrome (TOS). TOS is made up of a constellation of problems resulting from pathology at the thoracic outlet in the neck. Busy specialty practice sees multiple affected patients in every clinic, but TOS can often be difficult to diagnosis. Thoracic Outlet Syndrome explores all possible ancillary care issues surrounding this complex condition, including rehabilitation, disability, natural history and medicolegal issues, and aims to stimulate research, discussion and a sense of community between professionals involved in this area. Vascular and thoracic surgeons, neurosurgeons, neurologists, psychiatrists and psychologists, physical therapists, occupational medicine specialists and pain specialists will find this book a must read for successful treatment, referral and diagnosis of TOS in clinical practice.

Dieses weltweit bewahrte Standardwerk uber die zerebrale Computertomographie wurde voellig neu uberarbeitet und durch Einbeziehung der Kernspintomographie erweitert. Der Leser erhalt eine systematische Darstellung der Diagnose und Differentialdiagnose von nahezu allen Hirngeschwulsten im Computer- und Kernspintomogramm unter Berucksichtigung klinischer Aspekte. Auch Schadelbasis- und Orbita-Prozesse werden mit einbezogen. Grundlage dieses Werkes bildet die umfangreiche Erfahrung der Autoren mit der Computer- und Kernspintomographie bei fast 10.000 Patienten mit verifizierten raumfordernden intrakraniellen Prozessen und Orbita-Erkrankungen. Hervorzuheben ist der umfangreiche Abbildungsteil, in dem nicht nur die haufigsten Geschwulstarten anhand typischer Computer- und Kernspintomogrammen besprochen, sondern auch die seltenen Tumoren und atypischen Lokalisationen demonstriert werden. Fur die Einteilung der Tumorgruppen war die neue WHO-Klassifikation massgebend. In der sehr ausfuhrlichen Differentialdiagnose werden samtliche nicht tumorbedingten raumfordernden intrakraniellen Prozesse ausfuhrlich eroertert: entzundliche Gehirnerkrankungen, Gehirnerkrankungen im Zusammenhang mit AIDS, akute Entmarkungskrankheiten, Granulome, Zysten, Parasiten, Hirnblutungen, Gefassmissbildungen und Hirninfarkte.