Das Buch befasst sich mit samtlichen Aspekten der tiefen Hirnstimulation. Medizinisches, psychologisches und technisches Hintergrundwissen wird verstandlich vermittelt. Es geht aber auch auf alltagliche Probleme und so genannte Banalitaten ein, weil gerade diese oft zu kurz kommen und auf den ersten Blick zu simpel erscheinen um hinterfragt zu werden. Das Buch richtet sich in erster Linie an Patienten und deren Angehorige, aber auch Neurologen, Psychiater, Psychologen und Vertreter anderer Gesundheitsberufe sind eingeladen, sich uber die vielen Aspekte und Anwendungsgebiete der tiefen Hirnstimulation in einfacher und kompakter Weise zu informieren.

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Selected as a Doody's Core Title for 2021! Written by experts from around the world, the latest edition of this leading reference features contributions from both neurosurgeons and orthopaedic surgeons. Presenting the full scope of spinal surgery, chapters discuss anatomy, biomechanics, complications, instrumentation, preoperative and postoperative care, and other core topics for surgeons. And numerous illustrations and clinical video clips provide critical visual context.   New chapters detail current surgical techniques for idiopathic scoliosis procedures. Over half of the authors are new—bringing fresh perspectives and approaches to surgical preparation and techniques. Technical procedures are written in an easy-to-follow, step-by-step format. Covers a wide spectrum of spinal deformities, degenerative disorders, injuries, and traumatic conditions. Now with more than 4,000 illustrations—including figures that accurately depict anatomy and procedures, and tables and algorithms for absorbing information quickly. Enrich Your Ebook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Anche se gli ultimi anni hanno visto uno sviluppo tumultuoso della ricerca oncologica, i tumori restano la causa di morte del 30% degli italiani.

Gli avanzamenti terapeutici facilitano la guarigione e prolungano la vita, ma proprio per questo rendono piu evidenti gli effetti indesiderati delle terapie e complicazioni delle neoplasie prima meno frequenti; in molti casi il danno da trattamento, piuttosto che quello dovuto alla neoplasia primitiva, diventa il principale azzardo per la qualita della vita e la sopravvivenza dei pazienti.

Questo volume, insieme necessario e nuovo nel panorama della letteratura medica italiana, ne prende atto e presenta una revisione aggiornata e completa delle patologie del sistema nervoso centrale e periferico associate ai tumori e al loro trattamento.

Scopo del volume e di presentare un approccio integrato tra specialisti che deve vedere il neurologo e l oncologo in dialogo, e in grado di sviluppare una nuova capacita clinica super-specialistica la neuro-oncologia .

Molti sono gli esperti che hanno contribuito alla sua preparazione mettendo in comune conoscenze su temi che variano dalle complicazioni metastatiche, a quelle della terapia chirurgica dei tumori, della radio- e chemio-terapia, alle sindromi paraneoplastiche, alla terapia del dolore, al delirium e alle alterazioni affettive associate alla malattia.

Il libro si rivolge in particolare a neurologi, oncologi, palliativisti e chirurghi, ma e certamente utile ai medici di medicina generale e a tutti gli operatori che sono quotidianamente coinvolti nell impegnativa opera di prendersi cura dei pazienti oncologici."

The complex, highly technological field of neurovascular surgery is quickly expanding, encompassing traditional surgical approaches, as well as endovascular and neurointerventional techniques. The last decade has seen increased cross-specialty interest in utilizing minimally invasive techniques to help prevent and treat cerebrovascular disease. Concurrently, there has been important research analyzing the efficacy of surgical methods versus endovascular approaches - and the clip versus coil discussion is covered herein. Written by 21st Century pioneers in the field, this second, cutting-edge edition offers the latest science throughout 1,400 pages - and a remarkable video library - covering anatomy, diagnosis, epidemiology, history, treatment indications, technical nuances, outcomes, and complications. Internationally renowned experts from across the globe share clinical pearls and best practices, from the research lab to the ER to the OR. Medical, surgical, endovascular, cerebral revascularization, bypass surgery, radiation therapy, and other procedures are covered in depth. Evidence-based and transdisciplinary, the second edition covers the full spectrum of neurovascular pathologies, preoperatively and postoperatively, including: Ischemic Stroke and Vascular Insufficiency Cerebral and Spinal Aneurysms Cerebral and Spinal Arteriovenous Fistulae and Malformations Vascular Tumors Carotid Artery Disease Moya-Moya Disease Revascularization techniques Organized into 11 primary sections, 99 richly illustrated chapters, and more than 140 videos, this volume is an invaluable, one-stop reference tool. It is a must-have for general, vascular and endovascular neurosurgeons; interventional radiologists; neurologists; critical care practitioners; and neuro-rehabilitation specialists.

A chronic migraine is a condition which is both prevalent and disabling, and which has a great impact on society as a whole. The accurate diagnosis, workup, and treatment of a migraine requires a multidisciplinary approach, involving primary care physicians, neurologists, pain management specialists, mental health specialists, alternative practitioners, and surgeons. Across the spectrum of migraine patients, the most challenging are those deemed refractory to conventional therapy. These patients may be surgical candidates, and are best served in a multidisciplinary, patient-centred model of migraine care. Migraine Surgery should serve as a reference to any practitioner dealing with the migraine patient. The fundamentals of migraine diagnosis and workup are reviewed, in addition to conventional therapies. We review the medical optimisation of the migraine patient, and establish what it means to have an intractable migraine. We discuss the role of the allied health professions in the management of chronic migraines, with chapters on psychological considerations, complementary medical management, and exercise. Furthermore, the standard interventional treatment of migraines is presented, in addition to surgical therapies, with an emphasis on patient selection, surgical technique, and complication avoidance.

Spinal cord injury (SCI) results from damage to the spinal cord due to trauma or disease and leads to partial or complete paralysis. Following SCI, physiological and lifestyle changes can lead to poor health outcomes. However, advances in injury stabilisation, medical treatment and rehabilitation have led to an increase in life expectancy. In this book, the authors present current research on the causes, risk factors and management of spinal cord injury. Topics include pain management following spinal cord injury; exercise training and its relation to slow bone loss in SCI; palliative and therapeutic strategies for SCI; NO-cGMP signalling in bulbospinal respiratory pathway after cervical spinal cord injury; and posterior pedicle screw fixation for thoracolumbar burst fractures.

For centuries, scientists had only one way to study the brain: wait for misfortune to strike - strokes, seizures, infections, lobotomies, horrendous accidents, phantom limbs, Siamese twins - and see how the victims changed afterwards. In many cases their survival was miraculous, and observers marvelled at the transformations that took place when different parts of the brain were destroyed. Parents suddenly couldn't recognise their children. Pillars of the community became pathological liars and paedophiles. Some people couldn't speak but could still sing. Others couldn't read but could write. The stories of these people laid the foundations of modern neuroscience and, century by century, key cases taught scientists what every last region of the brain did. With lucid explanations and incisive wit, Sam Kean explores the brain's secret passageways and recounts the forgotten tales of the ordinary individuals whose struggles, resilience and deep humanity made neuroscience possible.

Over the past 20 years a silent revolution in functional neurosurgery has been unfolding. This revolution, still in the making, is the development of cortical electrical neuromodulation. No book covering the field of therapeutic cortical stimulation exists and only scarce attention has been given to this new field of neuromodulation in all textbooks and related books. As a result, the majority of neurologists and neurosurgeons are unaware of this technology. The aim of this book is thus twofold: cross-fertilisation among neurologists, other health professionals and functional neurosurgeons, and defining indications and limits of cortical stimulation, invasive and non-invasive. This textbook brings together leading authorities from all over the world and provides for the first time a complete account of the field. As a "teaching" tool, all, beginners and non, will find a conclusive word in a rapidly evolving field.

Seven Bypasses: Tenets and Techniques for Revascularization is the third book in a trilogy of bravura, technical nuance, and strategy by master neurosurgeon Michael Lawton. Like his first two books on aneurysms and AVMs, Seven Bypasses provides unparalleled firsthand insights and guidance on complex pathologies in vascular neurosurgery. The fundamentals of microsurgical anastomosis and the craft of bypass surgery are explored in depth with clinical pearls in every chapter. Lawton eloquently reveals the art of cerebral revascularization in exquisite, metaphorical detail. The surgeon performing bypass surgery is like an architect envisioning and building a beautiful structure. A bypass is designed to fit the patient's unique anatomy; blueprints designate anastomotic sites, connections, and conduits; the anastomoses are constructed; and the bypass is brought to life with pulsations, flow, and reperfusion. The book highlights Lawton's aesthetic, which has evolved from the common STA-MCA bypasses to IC-IC bypasses and elaborate arterial reconstructions. Key Highlights Stepwise discussion of the three anastomoses that form the building blocks of all bypasses: end-to-side, side-to-side, and end-to-end anastomoses Ten tenets delineate nuances of bypass: dexterity, preparing donors and recipients, establishing a working zone, temporary arterial occlusion, arteriotomy, suturing technique, tissue handling, knot tying, patency, and aneurysm occlusion Step-by-step guidance on the seven bypasses: EC-IC bypass, EC-IC interpositional bypass, arterial reimplantation, in-situ bypass, reanastomosis, IC-IC interpositional bypass, and combination bypass Strategies and algorithms for aneurysms organized by specific anatomical sites, including the MCA and the Sylvian cistern, ACA and the interhemispheric cistern, basilar artery and the basal cisterns, and PICA and the cisterna magna More than 1,500 radiographs, operative photographs, and exquisite illustrations drawn by artist Kenneth Xavier Probst elucidate anatomy, surgical principles, and clinical cases Dr. Lawton has bequeathed a remarkable treasure of knowledge to current and future generations of neurosurgeons and their patients. The Seven series is destined to be an enduring classic for residents, fellows, and neurosurgeons specializing in the treatment of cerebrovascular disease, and for those who believe that manual dexterity and technical skill still matter.

This book addresses multiple principles of carotid endarterectomy in terms of cervical anatomy, surgical techniques, practical cases and frequent questions stemming from clinical practice. Carotid endarterectomy (CEA) is an effective way to the treatment of carotid artery stenosis, which significantly reduce the risk of stroke. This book covers the key concepts and common question in CEA. It is a practical book focusing on basic surgical technical techniques, but not covers controversial issues.

Meningiomas are the most frequently reported neuro-oncologic condition, accounting for 12% to 30% of all primary intracranial tumors. The first case of intracranial meningioma treated with stereotactic radiosurgery was reported by Backlund E-O in 1971. Since then, more than 200,000 meningiomas have been treated with stereotactic radiosurgery worldwide to date. The large number of patients treated using this method is due to the fact that meningiomas are frequently located in critical areas and microsurgery is often associated with severe and permanent neurological complications. This book discusses the advantages, risks and limits of stereotactic radiosurgery relating to all regions of interest for a neuroradiosurgical approach for the treatment of central nervous system meningiomas. Firstly, it presents an introduction focusing on the "state of the art". It then discusses the physics, imaging, neurological and neuro-oncological issues in multidisciplinary management. Lastly, it features a summary of results, including the most recent published papers regarding all the locations involved in the stereotactic radiosurgery treatment as well as new approaches to meningiomas, with particular reference to the hypofrationated treatments. Intended for anyone involved in the neuroradiosurgical treatment of brain diseases, the book provides an up-to-date overview of the latest stereotactic radiosurgery treatment of central nervous system meningiomas.

" Four stars] Could not be published at a better time... superb illustrations, well-referenced text... technique insights... not only a superb book, but also one with historical significance... unparalleled in the book literature on aneurysm clipping. Doodys Review"

"Seven Aneurysms: Tenets and Techniques for Clipping" combines the instructive nature of a textbook with the visual aspects of an atlas to guide readers through the surgical principles, approaches, and techniques they need to dissect and clip cerebral aneurysms.

Comprised of three concise sections, the book distills the distinguished author's vast experience into a series of easily accessible tutorials presented through clear, systematic descriptions and stunning, full-color illustrations. The first section explains the critical concepts and basic tenets of aneurysm microsurgery followed by a section on the various craniotomies and exposures necessary for successful clipping. The final section covers microsurgical anatomy, dissection strategies, and clipping techniques for each of the seven most common aneurysm types that are the focus of this book.

Features: Strategies for handling the seven aneurysms most often seen by neurosurgeons: PCoA, MCA, ACoA, OphA, PcaA, basilar bifurcation, and PICA 383 full-color surgical photographs demonstrate operative techniques; 77 high-quality drawings display anatomy and spatial relationships Succinct text facilitates quick reading and easy reference

Clipping remains an essential treatment method for the most frequently encountered aneurysms. This must-have guide will enable neurosurgery residents, fellows, or practicing neurosurgeons to handle the majority of the aneurysms they will encounter with confidence and poise.

This practical guide for trainees and advanced practice providers covers the essential management of hospitalized patients with acute neurologic conditions. Divided into five sections, this text serves as an incredibly easy-to-use, visually accessible, how-to manual that covers exactly what every responding clinician needs to know to care for the patient in front of them. The first section provides tangible guidance about how to pre-round, structure a presentation, examine neurologically ill patients, and interpret the core diagnostics obtained in many neurology patients: CT, MRI and EEG. The next three sections cover common complaints encountered in the hospital: spanning from non-vascular admissions, vascular & stroke neurology topics, and core neurocritical care principals and chief complaints. Throughout are checklists, scoring systems, pro-tips, images, helpful reminders, as well as concise summary of the pertinent literature. This is an ideal guide for medical students, neurology & neurosurgery trainees and advanced practice providers, as well as experienced professionals who want to brush up on the latest updates.

A perfect blend of medical drama and spiritual insight, "Gray Matter" is a fascinating account of Dr. David Levy's decision to begin asking his patients if he could pray for them before surgery. Some are thrilled. Some are skeptical. Some are hostile, and some are quite literally transformed by the request. Each chapter focuses on a specific case, opening with a detailed description of the patient's diagnosis and the procedure that will need to be performed, followed by the prayer "request." From there, readers get to look over Dr. Levy's shoulder as he performs the operation, and then we wait--right alongside Dr. Levy, the patients, and their families--to see the final results. Dr. Levy's musings on what successful and unsuccessful surgical results imply about God, faith, and the power of prayer are honest and insightful. As we watch him come to his ultimate conclusion that no matter what the results of the procedure are, "God is good," we cannot help but be truly moved and inspired.

Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.

This atlas serves as a comprehensive working reference for a wide range of clinicians practicing in the field of clinical neurophysiology, including adult and pediatric neurologists, epileptologists, neurocritical care specialists, and electroneurodiagnostic technologists. Covering EEG, EMG, MEG, evoked potentials, sleep and autonomic studies, EP, and intraoperative monitoring techniques, expert authors share examples of common and novel artifacts and highlight signature features to help practitioners recognize patterns and make accurate distinctions. This visual compendium of information in atlas format addresses the artifact in all areas of clinical neurophysiology and highlights the traps and pitfalls that can taint studies and lead to misdiagnosis if not properly identified. Atlas of Artifacts in Clinical Neurophysiology provides full-page examples of waveforms and recordings to enhance appreciation of the nuances involved in distinguishing artifacts from neurological findings that require intervention. With the most up to date information available on artifact present during procedures in both adult and pediatric patients, this book provides readers with an in-depth understanding of artifact interpretation that is essential to any clinician working in the field of clinical neurophysiology given the ubiquitous nature of artifact during electrophysiological recording. Key Features: The only dedicated reference on artifacts in all areas of clinical neurophysiologic testing Large-format examples of both common and unusual artifacts encountered in each procedure category Up-to-date text in each chapter provides greater depth of explanation Draws on the expertise and clinical wisdom of leading practitioners to develop mastery in recognizing artifacts and avoiding diagnostic pitfalls Includes access to the digital book

This open access book presents the diagnosis, investigation and treatment of neurovascular diseases, and offers expert opinions and advice on avoiding complications in neurovascular surgery. It also covers complication management and post-operative follow-up care. The book is divided in to three parts; the first part discusses common approaches in neurovascular surgery, describing the steps, indications for and limitations of the approach, as well as the associated complications and how to avoid them. The second part addresses surgical treatment based on pathology, taking the different locations of lesions into consideration. The third part focuses on the technological developments that support neurovascular surgery, which may not be available everywhere, but have been included to help vascular surgeon understand the principles. This book is a guide for young neurosurgeons, neurosurgery residents and neurosurgery fellows, as well as for medical students and nurses who are interested in neurosurgery or are associated with this field in any way. It is also a useful teaching aid for senior neurosurgeons.

This book offers essential guidance on selecting the most appropriate surgical management option for a variety of spinal conditions, including idiopathic problems, and degenerative disease. While the first part of the book discusses the neuroanatomy and biomechanics of the spine, pain mechanisms, and imaging techniques, the second guides the reader through the diagnostic process and treatment selection for disorders of the different regions of the spine, based on the principles of evidence-based medicine. I.e., it clearly explains why a particular technique should be selected for a specific patient on the basis of the available evidence, which is carefully reviewed. The book identifies potential complications and highlights technical pearls, describing newer surgical techniques and illustrating them with the help of images and accompanying videos. Though primarily intended for neurosurgeons, the book will also be of interest to orthopaedic surgeons, specialists in physical medicine, and pain specialists.

Considerable impetus was given to the study and understanding of cere brovascular anatomy by Thomas Willis and his contemporaries in the seventeenth century, yet almost two hundred years were to pass before further significant advances were made in this field. Then, from the mid nineteenth century onwards, the dark ages of cerebrovascular research gradually lifted through the efforts of such workers as Luschka, Heubner, and Windle, whose pioneering anatomical studies formed the basis of the present-day understanding of the morphology of the cerebral circulation. The turn of the century saw an increasing influence of the early neurolo gists in describing anatomy of cerebral vessels in relation to their areas of distribution and to the production of focal deficits through specific vascu lar lesions and anomalies. Later still, Padget and others made important observations concerning phylogenetic and developmental aspects of the cerebral circulation. These anatomical and clinical studies were remarkable enough but the real breakthrough in investigating cerebral pathophysiology and in devis ing appropriate corrective neurosurgical procedures had to await the re markable advances in technology of the past fifty years. These began with the advent of cerebral angiography with all its subsequent refinements and progress has been accelerated through establishing noninvasive Doppler and high resolution ultrasound imaging techniques, methods for the accu rate measurement of cerebral blood flow, CT scanning, PET scanning, and, most recently, imaging and metabolic NMR scanning.

The Cervical Spine is the most comprehensive, current, and authoritative reference on the cervical spine. Prepared by internationally recognized members of The Cervical Spine Research Society Editorial Committee, the Fifth Edition presents new information, new technologies, and advances in clinical decision making. The text provides state-of-the-art coverage of basic and clinical research, diagnostic methods, and medical and surgical treatments, bringing together the latest thinking of the foremost orthopaedic surgeons, neurosurgeons, neurologists, rheumatologists, radiologists, anatomists, and bioengineers. Chapters cover anatomy, physiology, biomechanics, neurologic and functional evaluation, and radiographic evaluation and address the full range of pediatric problems, fractures, spinal cord injuries, tumors, infections, inflammatory conditions, degenerative disorders, and complications. Accompanying the text is a website with the fully searchable text plus a color image bank.

The one-stop resource on deep brain stimulation for functional neurosurgeons! Deep brain stimulation (DBS) is used to modulate dysfunctional circuits in the brain with stimulation pulses applied to specific target areas of the brain. Globally, DBS procedures have been most commonly performed for Parkinson's disease and essential tremor, but there are now new and growing research efforts studying DBS for psychiatric disorders and epilepsy. Deep Brain Stimulation: Techniques and Practices written by the Society for Innovative Neuroscience in Neurosurgery along with Dr. William S. Anderson and distinguished experts presents the latest DBS approaches. The book begins with a history of DBS, general frame-based techniques, patient selection primarily for movement disorders, multidisciplinary collaboration, and ethical considerations. Subsequent chapters detail diverse technologies and disease-specific treatment for Parkinson's disease, essential tremor, dystonia, OCD, epilepsy, major depression, Tourette syndrome, emerging psychiatric indications, and pediatric applications. Key highlights Lead placement techniques utilizing currently available customized platforms and robotics Microelectrode recording and image-based direct targeting with MRI and CT to enhance lead placement Lesioning methods including radiofrequency, and MR-guided focused ultrasound Discussion of recent innovations in tractography to delineate white matter tracts in the brain and closed loop stimulation DBS has helped thousands of patients with intractable conditions, allowing for a programmable therapy with durable treatment effect. This remarkable guide provides the essentials for functional neurosurgeons to pursue intraoperative research opportunities in this growing subspecialty and incorporate DBS into clinical practice. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This practical question and answer book covers topics within the field of neurocritical care, including aspects of neurology, neurosurgery, general critical care, and emergency medicine.  The updated second edition, with hundreds of new and revised test items, contains two full length practice exams that mimic the tone and scope of the recently introduced American Board of Psychiatry and Neurology (ABPN) certifying exam in Neurocritical Care, based on approval from the American Board of Medical Specialties (ABMS).  At the conclusion of each exam, answer choices, rationale, and references are provided.  The book is geared towards critical care fellows, but may also be useful for residents in the fields of neurology, neurosurgery, emergency medicine, and internal medicine.

Our understanding of human neuro-anatomy, and ability to safely access lesions in complex locations, are in continuous evolution. The subcortical white matter space is among the most intricate, yet least understood, regions of the brain, with regards to its billions of connections and the subtle clinical and clinical functions it subserves. Neurosurgical procedures in the subcortical space and intraventricular system have been traditionally very difficult due to their depth, the need for brain retraction, and limited understanding and imaging capability of this region. Common lesions encountered in the subcortical space include brain metastases, gliomas, and intracerebral hemorrhage. Surgical access to this region has classically been hindered, and is highly limited by evolving technological applications to medicine and surgery. Traditionally, the technology (optics, imaging, resection devices, illumination) needed to perform safe subcortical surgery was not commensurate with the surgeon's needs. Over the past decade, major strides in our ability to image, navigate, and safely access subcortical tumors and other lesions have been made. These include parafascicular, trans-sulcal approaches that may be channel-based to provide safe retraction of the cortical and subcortical matter. A confluence of optical, computational and mechanical technology have greatly enabled our ability to treat such lesions, and include advanced MR imaging such as diffusion tractography, neuronavigation, channel-based access ports, exoscopic visualization, fiber-optic illumination, and novel resection devices. Parafascicular, channel-based subcortical surgery is a relatively new field with evolving indications and approaches that promises to evolve considerably over the next several decades. We aim to develop the first comprehensive reference text compiling the known evidence and experience from expert practitioners in the field of subcortical parafascicular surgery. This book will provide a major foundation for future development of the field, and be a first and definitive reference for decades to come. Subcortical Neurosurgery: Open and Parafascicular Channel-Based Approaches for Subcortical and Intraventricular Lesions will be the definitive reference on surgery of the subcortical region. It will comprehensively discuss all aspects of treatment of subcortical and intraventricular lesions, including neuroanatomy and neuroimaging of the subcortical space, principles of parafascicular subcortical channel-based surgery, common indications and approaches, and focused chapters for common subcortical lesions. The first section of the reference focuses on the intricate anatomy and neuro-imaging of the subcortical space and ventricular system, with special emphasis on intricate white matter tracts and diffusion tractography imaging. The next section of the book discusses principles of both open and parafascicular, channel-based approaches to subcortical and intraventricular lesions, in addition to workhorse approaches to common subcortical compartments. Finally, specific pathological subcortical lesions that can be commonly addressed via parafascicular channel-based approaches, including brain metastases, gliomas, and intracerebral hemorrhage will be addressed. Authored by experts in the field of subcortical neurosurgery, this book was developed to provide a unique, comprehensive text for neurosurgeons, neuro-radiologists, and trainees from a variety of specialties interested in evolving minimally disruptive access and treatment of the subcortical space.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This text is designed to function as a comprehensive guide/companion that will not only facilitate the decision-making process for the surgeon, but also help young surgeons build a successful career in skull base surgery. It is divided into six main sections: The first section details the general principles that every skull base surgeon needs to be acquainted with - skull base anatomy, developing a multidisciplinary skull base team, operating room equipment, surgical instruments, and modern imaging technologies. These are the key elements that play a major role in optimizing functional outcomes and patients' quality of life. Following this, the compartmental anatomy chapters set the stage for understanding the technical and surgical nuances of each location. The subsequent five sections are organized as anatomical compartments or regions of the skull base. Every region is organized in the same format for uniformity and ease of use. Each section includes the available treatment choices to each compartment, and describes the relevant pathologies. The contribution of worldwide leaders including neurosurgeons and otolaryngologists provides top-level expertise in how to tackle each pathology. The surgical approaches chapters that lead each anatomical section describe operative techniques in a clear. stepwise fashion with accompanying intra-operative photos and surgical videos. In the individual pathology chapters, different pathological subtypes are described with representative radiographic images of clinical case examples. Accompanying each pathology is a treatment algorithm based on tumor morphology, pre-operative clinical status, and the goal of maximum functional preservation with a brief description of surgical approaches. This will serve as a roadmap that will help the reader to easily reach a decision of how to treat each skull base pathology. The general theme is functional and anatomical preservation of key neurovascular structures. Setting such structures as a target and planning an approach that minimizes iatrogenic damage to these structures will lead the surgeon down the road of either open, endoscopic, or a combination of both approaches. A comprehensive book that is versatile to serve as a handbook as well as a detailed reference for skull base surgery does not currently exist. In addition, combining the two main surgical schools represented by endoscopy and open surgery into one reference enhanced by treatment algorithms is another unique feature.