Das vorliegende Buch prasentiert das gesamte klinische und wissenschaftliche Spektrum der neurologischen Beatmungsmedizin. Es wendet sich an alle AErzte, die beatmete neurologische Patienten betreuen, wie Neurologen, Anasthesisten, Internisten, Pneumologen, Intensivmediziner, Schlafmediziner und Palliativmediziner. Das Werk vermittelt sowohl die fur die neurointensivmedizinische und neurorehabilitative Behandlung als auch die fur die optimale Versorgung ausserklinisch beatmeter Patienten erforderlichen Kenntnisse. Zahlreiche Handlungsempfehlungen fur das Vorgehen bei den oft schwierigen Beatmungs- und Atemwegssituationen machen das Werk besonders praxistauglich.

This second edition is written by renowned experts in neurosurgery, neurology, physics, and radiation oncology, many of whom are pioneers of radiosurgery. Throughout more than 30 detailed chapters, the authors share their vast expertise on this highly precise, minimally invasive form of radiation therapy. The first few chapters lay a foundation for understanding the differentiations in types of SRS technology: Leksell Gamma Knife, Novalis, Linac and Proton Beam Radiosurgery, and Cyberknife, followed by an explanation on the physics and radiobiology of SRS. The remaining chapters provide a detailed discussion of all pathologies and disorders currently treated. Highlights: Radiosurgical procedures for a wide range of intracranial conditions/diseases including arteriovenous malformations, meningiomas, pituitary adenomas, trigeminal neuralgia, obsessive-compulsive disorder, epilepsy, ocular disorders, pediatric brain tumors, and gliomas. Important updates on skull base tumors, functional disorders, and brain metastases. Evidence-based findings covering indications, patient selection, benefits, limitations, outcomes, potential complications, and alternative treatment modalities. This updated reference tool is an invaluable, comprehensive guide to current concepts in SRS. It is a must-have resource for neurosurgeons, radiation oncologists, neuro-radiologists, and medical physicists, from residents to advanced clinicians.

The complex, highly technological field of neurovascular surgery is quickly expanding, encompassing traditional surgical approaches, as well as endovascular and neurointerventional techniques. The last decade has seen increased cross-specialty interest in utilizing minimally invasive techniques to help prevent and treat cerebrovascular disease. Concurrently, there has been important research analyzing the efficacy of surgical methods versus endovascular approaches - and the clip versus coil discussion is covered herein. Written by 21st Century pioneers in the field, this second, cutting-edge edition offers the latest science throughout 1,400 pages - and a remarkable video library - covering anatomy, diagnosis, epidemiology, history, treatment indications, technical nuances, outcomes, and complications. Internationally renowned experts from across the globe share clinical pearls and best practices, from the research lab to the ER to the OR. Medical, surgical, endovascular, cerebral revascularization, bypass surgery, radiation therapy, and other procedures are covered in depth. Evidence-based and transdisciplinary, the second edition covers the full spectrum of neurovascular pathologies, preoperatively and postoperatively, including: Ischemic Stroke and Vascular Insufficiency Cerebral and Spinal Aneurysms Cerebral and Spinal Arteriovenous Fistulae and Malformations Vascular Tumors Carotid Artery Disease Moya-Moya Disease Revascularization techniques Organized into 11 primary sections, 99 richly illustrated chapters, and more than 140 videos, this volume is an invaluable, one-stop reference tool. It is a must-have for general, vascular and endovascular neurosurgeons; interventional radiologists; neurologists; critical care practitioners; and neuro-rehabilitation specialists.

Part of the Neurosurgery by Example series, this volume on functional neurosurgery presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore the spectrum of clinical diversity and complexity within functional neurosurgery, including essential tremor, thalamotomy, parkinson's disease, epilepsy, dystonia, and more. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Functional Neurosurgery is appropriate for neurosurgeons who wish to learn more about a subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair.

Updated atlas refl ects state-of-the-art advances in spine and peripheral nerve procedures Written by a Who's Who of renowned spine surgeons, the third edition of Neurosurgical Atlas: Spine and Peripheral Nerves provides a detailed tutorial on the latest surgical procedures. The three comprehensive spine sections cover decompression modalities followed by fusion/instrumentation and fixation. Rounding out these sections are special topics such as vascular malformations in the spinal cord, stereotactic radiosurgery in the thoracic spine, and lumboperitoneal shunting. The peripheral nerves section includes treatment of conditions including carpal tunnel, brachial plexus, meralgia paresthetica, and cervical nerve root avulsion. Throughout the book, the authors provide minimally invasive options and clinical pearls on patient selection, preoperative preparation, anesthesia, operative positioning, surgical methodologies, patient monitoring, and common complications. Key Features Anterior, posterior, transoral, and lateral approaches to the craniocervical junction, subaxial cervical spine; and operations specific to the cervicothoracic junction Thoracic spine techniques for burst fractures, vertebral body metastasis, penetrating spine wounds, tumors, etc. Lumbosacral spine approaches for herniation, degenerative disease with multiplanar deformity, spondylolisthesis, and more Close to 700 illustrations and color photographs elucidate key concepts Superb videos demonstrate hands-on techniques This book is a must-have reference for neurosurgery residents seeking in-depth knowledge of spine and peripheral nerve procedures prior to scheduled cases. It will also benefit veteran neurosurgeons looking for clinical insights on infrequently performed surgeries.

Rapid diagnosis and treatment are crucial to successful outcomes in infections involving the central nervous system, which can cause significant neurological morbidity and mortality. Neurosurgical Infectious Disease: Surgical and Nonsurgical Management is a comprehensive guide that gives surgeons the core knowledge they need to diagnose, treat, and prevent infectious diseases of the central nervous system. Key Features: Emphasizes newer surgical techniques, including: endoscopy, neuronavigation, and intraoperative guidance Covers contemporary radiologic diagnostic techniques and provides excellent imaging examples Includes chapters on antibiotic prophylaxis, intracranial infection, and the infection of implanted devices This excellent neurosurgical reference will be an essential part of the armamentarium used by neurosurgeons and infectious disease specialists in their daily practice.

Although decompressive craniectomy is a surgical procedure that has been with us for the past 100 years, its prognostic value in long-term outcomes remains doubtful and its use is at a crossroads. Three randomized trials and numerous cohorts, along with comparative studies over the past 15 years (as shown in the presented figure) have significantly improved our understanding of this simple surgical procedure. In writing this book, the authors not only tried to present state-of-the-art evidence describing the molecular and cellular cascades discovered during the past 40 years and current critical care management of traumatic brain injury, but also found it very appropriate to consider the views of scientists who have contributed immensely in understanding the pathobiology of severe head injury (Simard and Fiskum). The current values of multimodality monitoring of neurochemical processes (Badjatia, Bullock) and the contribution of maximal medical management through guidelines (Stein, Ullman) help to understand how far research concerning the management of head injury has come. The authors deem it important to present the personal views of leading scientists who have conducted two high impact randomized controlled trials (Cooper, Hutchinson, Servadei and Sahuquillo) and the experiential views of decompressive craniectomy during the Operation Iraqi Freedom and Operation Enduring Freedom campaigns (Rosenfeld, Neal). Joint discussions of ethical views between the next of kin and surgeons as well as the value of informed consent constitute the ultimate objective before proceeding with the surgical procedure (Honeybul). The promise of the future, which hangs on additional imaging biomarkers with higher predictive values is presented in a systematic review (Aarabi) that stresses a clear view of the extent of rostral-caudal injury severity to the functional connectivity network, and the connectome on magnetic resonance imaging before proceeding with decompressive craniectomy in patients with low motor subscores.

Master spine surgeons Alexander R. Vaccaro, Richard G. Fessler, and a cadre of esteemed co-editors have compiled the most comprehensive textbook to date detailing minimally invasive spine (MIS) versus open spine surgery techniques. Controversies in Spine Surgery, MIS versus OPEN: Best Evidence Recommendations features debates by renowned experts on one of the most provocative topics in spine surgery. Twenty-four chapters systematically organized into four sections - degenerative, trauma, tumor, and other issues, cover procedures and underlying pathologies, backed by a large, diverse body of literature. MIS and open approaches are thoroughly compared and contrasted in each chapter. Evidence is presented and analyzed in an objective manner with 'opposing sides' presenting differing opinions and techniques, resulting in a synchronous collection of pros and cons. Every chapter is masterfully summed up by the book's editors - each of whom have varying stances on the topics at hand. This unique 'duel' and 'duet' discussion enables readers to assimilate information, benefit from the balanced harmony between divergent opinions, and reach their own conclusions. Key Highlights Comparative risks, benefits, complications, and outcomes for a full spectrum of lumbar, thoracic and cervical procedures MIS versus open approaches for lumbar stenosis, synovial cysts, lumbar adjacent segment degeneration, degenerative scoliosis, flatback syndrome, thoracic disc herniation, and dural tears Tumor resection and stabilization, quality of life issues, and potential advantages and risks of MIS techniques Key differences in MIS versus open operations such as radiation exposure and costs Analysis of 3-D navigational imaging to improve outcomes and reduce radiation exposure and operating time This book is a tremendous, evidence-based tool to guide spine surgeons as they make important decisions on selecting the most optimal spine surgery techniques. It is a must-have resource for all resident and veteran orthopaedic surgeons and neurosurgeons who specialize in treating patients with spine conditions.

The limbic system (also known as the paleomammalian brain) is a collection of brain structures located in the middle of the brain. It is not a discrete system itself but rather a collection of structures-anatomically related but varying greatly in function. The limbic system is the centre for emotional responsiveness, motivation, memory formation and integration, olfaction, and the mechanisms to keep ourselves safe (Neuropsychotherapist.com). This book is a guide to surgical procedures for the limbic system. Beginning with an overview of brain embryology and anatomy, each of the following sections covers surgical approaches for disorders in different parts of the limbic system. Procedures are explained in a step by step approach, with emphasis on anatomical markers and avoidance of complications. The final chapters discuss brain mapping during surgery, giant and unusual tumours, and vascular lesions. Authored by a team of highly experienced, Illinois and Wisconsin-based neurosurgeons, the book is enhanced by anatomical dissections, operative photographs and illustrations, and includes a DVD ROM demonstrating surgical procedures. Key points Guide to surgical procedures for the limbic system Step by step approach with emphasis on anatomical markers and avoidance of complications Highly experienced, Illinois and Wisconsin-based author team Includes DVD ROM demonstrating surgical procedures

Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys presents a unique way to approach the dating of neurological injury as imaged by modern computed tomography (CT), magnetic resonance (MR) and ultrasound (US). Chapters are presented in a logical progression beginning with the general appearance of normal brain and progressing to the way abnormalities manifest themselves. The emphasis in these discussions is on the appearance of edema and of hemorrhage, as these two findings are the brain's most common response to injury. This volume presents in a systematic fashion the principles involved in the interpretation of images of the central nervous system specifically in a medical-legal setting where concern exists about the occurrence and timing of an injury. Dating Neurological Injury: A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys is a welcome addition to institutional, medical, and legal libraries, and to the personal libraries of malpractice defense and plaintiff lawyers and physicians in the neurosciences (neurosurgery, neurology, neuropathology, and neuroradiology) involved in medical-legal issues.

Hippocrates of Cos was one of the first who described spontaneous subarachnoid haemorrhage without special knowledge about neuro-anatomy or neuro-physiology. This haemorrhage represented a life ending event of fate for him. Inventions like computed tomography or angiography gave better insight into the patterns of this life threatening disease. Progress in management was developed by new cranial approaches, new generations of clips and better intensive care modalities. The latter could be represented by the increasing use of nimodipine or the integration of the early sealing mode of an intracranial aneurysm after rupture within 72 hours. Endovascular therapies revolutionised aneurysm management, strengthening the interdisciplinary team-work of neuroradiologists, anesthesists and neurosurgeons. These changes in the past lead to a significant reduction in mortality, producing more survivors who suffer different stages of morbidity. Morbidity in this context is represented by physical handicaps and dependencies, but also mental, emotional and cognitive impairments. However, there are still some challenges to manage, like the cerebral vasospasm or delayed cerebral ischemia including spreading depolarisations, (prolonged) hydrocephalus, and cognitive long-term morbidity that may complicate a smooth and easy reintegration into daily life. Nevertheless, dealing with this long history and the aforementioned challenges, there is still the opinion that there is stagnation in the progress within this field of study. Scientists lack new ideas for surgical procedures or clips, endovascular devices do not always represent safe options, and medication providing protection for vasospasms still remains unknown. This book provides basic knowledge concerning this interesting disease pattern and introduces more intensive work in the field. It is written by a team of individuals from multiple disciplines that represent different parts of therapy management. The literature used is recent and promotes intensive private or independent study. The intended audiences for this book include students, residents, registrars, assistant physicians, and all physicians from neighbouring disciplines.

Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients.

This book is a comprehensive guide to the management of complex spine cases. Presented as a series of case studies, it brings together the experiences and knowledge of expert contributing specialists. Divided into five sections - Early Onset Scoliosis, Pediatric Spinal Deformity, Adult Spinal Deformity, Trauma and Tumors, and Cervical Spine - each part explains numerous cases relevant to that topic, describing the challenges, techniques for management, and pitfalls, for each one. Edited by highly experienced US-based spinal surgeons, including Alexander R Vaccaro from Thomas Jefferson University Hospital, Pennsylvania, this practical reference is further enhanced by more than 500 illustrations. Key points Comprehensive guide to management of complex spine cases Based on experiences and knowledge of contributing authors Edited by US-based specialists including Alexander R Vaccaro Includes more than 500 illustrations

In this book, the biology, current treatment modalities and new emerging therapeutic approaches and targets for glioma, a highly aggressive and invasive brain tumour, are described. The pathologic features of the most frequently WHO classified gliomas encountered in clinical practice, are reviewed. Molecular genetics and specifically the mutations that underlie brain tumours are outlined as is the inherited genetic susceptibility and lifestyle risk factors reflecting on glioma epidemiology. The clinical features of glioma as well as diagnostic methods that include conventional and advanced magnetic resonance imaging (MRI) and brain mapping are also discussed with an outline of emerging treatment options.

The latest management strategies for complex lesions of the craniovertebral junction Written by masters in the field, The Craniovertebral Junction: Diagnosis, Pathology, Surgical Techniques provides in-depth coverage of up-to-date management principles for this delicate anatomic region. After a brief introduction to anatomy, biomedical considerations, and embryology, the multidisciplinary team of authors, led by Professor Goel, discusses in detail the most innovative fixation and stabilization techniques for atlantoaxial dislocation, as well as congenital,infective, and acquired anomalies in the craniovertebral junction region. Each concise chapter focuses on a single pathology to guide readers through the nuances of these intricate and demanding surgical procedures. Features: Discusses in detail Professor Goel's groundbreaking treatment methods - now accepted as standards in the field Covers state-of-the-art protocols and techniques, including alternative treatment protocols for irreducible and rotatory atlantoaxial dislocation and more Introduces a novel concept of craniovertebral realignment Over 1,000 high-quality drawings, radiographs, and full-color photographs demonstrate surgery and anatomy and enhance the text Contains a full section Casebook featuring 22 well-illustrated cases displaying a wealth of pathology Text is rounded out by practical advice on how to manage trauma, degenerative disorders, infections, and tumors This fully illustrated manual fills the current gap in craniovertebral junction literature with the clear, accessible information every neurosurgeon, orthopedic surgeon, and spine surgeon needs.

In neurotechnology, deep brain stimulation (DBS) refers to a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson's disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. While DBS has proven helpful for some patients, there is potential for serious complications and side effects. This book presents current research on this cutting edge treatment. Success of functional stereotactic procedures is shown to depend on a variety of factors, including patient selection, methodology of choice and localisation of the target, and the experience of the neurosurgery team. Complications on the use of the procedure in the treatment of Parkinson's Disease are also presented. The use of Vagus nerve stimulation on treatment-resistant patients with major depression is discussed as well.

Multi-pronged approaches to pediatric neurovascular diseases Bridging the gap between the pediatric specialist unaccustomed to handling neurovascular pathologies and the neurovascular specialist unaccustomed to treating pediatric patients, this text covers the cutting-edge, multi-modal techniques for managing pediatric neurovascular disease, disorders, and malformations. It contains full descriptions and insightful perspectives on the most advanced surgical, endovascular, and medical treatments for cerebral aneurysms, arteriovenous fistulas, arteriovenous malformations, Galen's vein malformations, moyamoya disease, spinal vascular malformations, pediatric stroke, and more. Highlights: Easy-to-follow organization of disease topics according to endovascular, surgical, or medical treatment method Discussion of endovascular techniques and tools for angioplasty and stents in children, as well as how to manage possible complications such as stroke and hemorrhage More than 200 illustrations highlighting principles of disease pathology Review of the existing literature helps the clinician gain a full understanding of the fundamentals in neurovascular disease management With contributions from world-renowned experts, this is an exceptional clinical reference for neurosurgeons, neuroradiologists, neurointerventionalists, neurologists, and pediatricians seeking to gain expertise in a multi-pronged approach to pediatric neurovascular disease.

Neuroprosthetics is an area of intense scientific and clinical interest and rapid progress. Since the introduction of the cardiac pacemaker in 1932, we have seen developments that include cochlear prostheses, techniques for bladder and bowel control, deep brain stimulation, and restoration of mobility and respiration to paralyzed individuals.The chapters in this book have been contributed by authors who are recognized internationally in their fields. The result is a comprehensive and up-to-date review that will be invaluable to graduate students, clinicians and researchers in neuroprosthetics. It is broadly divided into three sections: Section 1 provides a core of knowledge that forms a foundation for the rest of the book, and covers the basics of neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; Section 2 describes current clinical applications of neuroprosthetics; Section 3 looks at future developments in the field.

An overview of practice and theory in both neural specialties, encouraging a broader therapeutic approach to problems such as movement disorders and intractable pain. The concept of this book is to merge neurological and neurosurgical principles and practice, for improved patient care. This includes a review of the basic neurosciences, especially neurogenetics. Details of the neurological examination and neurodiagnostic studies are oriented to specific clinical factors. Attention is directed to advances in molecular biology in the current research in metabolic disorders affecting the neurological system. There is a comprehensive approach to demyelinating diseases and dementia, as well as practical aspects in the diagnosis and management of neurological disorders caused by trauma, vascular lesions, neoplasms and infection. The goal is to share the expertise of both neural specialties in therapy of problems such as movement disorders and intractable pain. A general need for the above has become apparent, in an era of an aging population and increased incidence of neurological disorders. Frank P. Smith, MD, is Professor of Neurosurgery Emeritus, University of Rochester Medical Center

"An extraordinary story that you will pick up and finish in a few hours of remarkable reading. The account of her son's and her family's regeneration is simply inspiring. It will be instructive to any family with a child with a disabling condition. But as the account of a transfiguring experience and the sensitive interpretation of how it came about, it speaks to all of us."--Arthur Kleinman, Harvard Medical School, author of "Writing at the Margin"

"Ruthann Johansen's loving account of the aftermath of her son's traumatic brain injury is an extraordinary book, . . . at once a profound meditation about the inextricable relationship between language, story-telling, and self-formation and a moving account of how one young man reconstructed his life in dialogue with the solicitations and offerings of family, friends, and caring others. This book should be read by everyone who is interested in the nature of identity and selfhood."--Janice A. Radway, Duke University, author of "A Feeling for Books: The Book-Of-The-Month Club, Literary Taste, and Middle-Class Desire

"This book clearly asks the question: Who speaks for the traumatically brain injured? It should be required reading for all neuroscientists who are providers of care or who are diligently conducting research to find a therapy that truly produces recovery of function."--David A. Hovda, Professor of Neurosurgery and Director of the Brain Injury Research Center, University of California, Los Angeles

"A singular contribution to our understanding of brain injury as illness experience, of the family dynamics of care, and of the narrative nature of lives and brains. The writing is lyrical, moving, and scholarly, not by turns butat the same time. Johansen conveys mother love, feminist self-awareness, and a critical social perspective to provide a unique account of family life through continuing trauma."--Arthur W. Frank, author of "The Wounded Storyteller: Body, Illness, and Ethics

"This book is gripping and inspired. . . . It will be of great solace and usefulness to others who find themselves in such circumstances, part of the literature of family disaster. It will find an audience as well among all those concerned with what might be called the construction of the self, which would include a good many in various psychological fields."--F. Robert Rodman, author of "Not Dying: A Memoir

Here is a book that anyone interested in how the brain works will find fascinating and enjoyable. Written in a highly readable style, the book looks at how the damaged brain can be repaired and reconstructed.

The key to neuroscience's most exciting discoveries to date is the theory that is rapidly gaining adherents in the scientific community - the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. The author explains how the brain manufactures complex chemicals that foster growth in damaged brain cells, and how misguided ideas can adversely affect how physicians treat patients.

A best-selling volume in France and Spain, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.

Alle praktisch relevanten Themen der peripheren Nervenchirurgie sind in ubersichtlicher, stichwortartiger Form in diesem Kompendium zusammengefasst. Es wendet sich an Facharzte ebenso wie an AErzte in der Weiterbildung. Im Mittelpunkt stehen das diagnostische und therapeutische Vorgehen mit differenzierten Empfehlungen zur Therapieauswahl. Die Untersuchungsverfahren und chirurgischen Techniken sind mit zahlreichen Abbildungen beschrieben, dazu gehoeren als wichtige Behandlungsoption auch die motorischen Ersatzoperationen. Detailreiche Zeichnungen illustrieren die zugehoerige Anatomie als Grundlage des chirurgischen Handelns. Die Lasionen der Hirnnerven N. facialis und N. accessorius sind, da sie klinisch und therapeutisch viele AEhnlichkeiten mit den peripheren Nerven aufweisen, zusatzlich berucksichtigt.