In Neuroorthopadie Band 4 werden die Erkrankungen des zervikookzipitalen Ubergangs mit Beteiligung des Nervensystems in Diagnostik und Therapie, zumal deren operative Behandlung, diskutiert. Neben dieser nicht nur fur den Kliniker, sondern gerade auch fur den Praktiker wichtigen Diskussion war es wesentlich, abgrenzend auf vital bedrohliche Fehlbildungen, Erkrankungen und Verletzungen der oberen Halswirbelsaule und ihre zeitgemasse Behandlung einzugehen. Desweiteren aussern sich namhafte Vertreter der verschiedenen Fachdisziplinen zu den Problemen der Spondylolisthesis. Dieses zweite Arbeitsthema wurde gewahlt, da Krankheitswert und Prognose dieser Erkrankung und vor allem auch die Indikation zu konservativer und operativer Therapie haufig unterschiedlich und auch unzutreffend beurteilt werden. Besonders vielfaltig sind die Meinungen zum Problemkreis "Wirbelsaule in Arbeit und Beruf," die sich vor allem mit der arbeitsbedingten Belastung am Bau und der Begutachtung beschaftigen."

As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series devoted to Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the first part of each volume. In the second part of each volume, we publish detailed descriptions of standard operative proce.dures, furnished by experienced clinicians; in these articles the authors describe the techniques they employ and explain the advantages, difficulties and risks involved in the various procedures. This part is intended primarily to assist young neurosurgeons-in their post graduate training. However, we are convinced that it will also be useful to experienced, fully trained neurosurgeons."

Das Buch befasst sich mit samtlichen Aspekten der tiefen Hirnstimulation. Medizinisches, psychologisches und technisches Hintergrundwissen wird verstandlich vermittelt. Es geht aber auch auf alltagliche Probleme und so genannte Banalitaten ein, weil gerade diese oft zu kurz kommen und auf den ersten Blick zu simpel erscheinen um hinterfragt zu werden. Das Buch richtet sich in erster Linie an Patienten und deren Angehorige, aber auch Neurologen, Psychiater, Psychologen und Vertreter anderer Gesundheitsberufe sind eingeladen, sich uber die vielen Aspekte und Anwendungsgebiete der tiefen Hirnstimulation in einfacher und kompakter Weise zu informieren.

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In rare cases of stroke in children and youths, a likely cause is the idiopathic disease moyamoya, characterized by the slow and progressive stenosis and occlusion of the internal carotid artery and the arteries of the circle of Willis. A result of these stenoses is the formation of collaterals that are typically small and fragile, and liable to rupture. While there is no cure for moyamoya, a variety of surgical procedures can be performed to reestablish and maintain adequate blood supply to the affected brain areas. The procedures described here include various revascularization techniques and recommended bypasses. Key Features: With contributions from the world's most renowned bypass surgeons Perioperative management and considerations An overall practical approach to this painstaking high-end surgery Detailed criteria for analyzing the situation and choosing the appropriate procedure General principles of bypass surgery, direct and indirect revascularization, and combined revascularization techniques Step-by-step descriptions of these procedures Rescue strategies when repeat surgery is necessary Surgical Techniques in Moyamoya Vasculopathy is an indispensable guide for the experienced neurovascular surgeon. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This book provides neurosurgeons and trainees with the latest techniques in spinal surgery. Divided into three sections, each is dedicated to surgical procedures in a key region of the spine - cervical, thoracic and lumbar. Each topic is presented in a step by step process covering anatomy, indications and contraindications, techniques and outcomes. Authored by internationally recognised, Philadelphia-based experts in the field, this invaluable text is enhanced by more than 200 surgical images and illustrations. Key points Practical guide to latest techniques in spinal surgery for neurosurgeons and trainees In depth coverage of procedures for each section of the spine - cervical, thoracic and lumbar Internationally recognised, Philadelphia-based author team Highly illustrated with surgical images and illustrations

Bislang konkurrenzlos auf dem deutschsprachigen Fachbuchmarkt: Das anschauliche TMS-Buch gibt Einsteigern und Fortgeschrittenen den aktuellen und umfassenden Uberblick uber alle wichtigen Themen. Die transkranielle Magnetstimulation erlaubt die schmerzlose Stimulation des menschlichen Gehirns. Sie ist eine neue, hoch innovative und nicht-invasive Methode mit breit gefacherten Einsatzmoglichkeiten, u.a. in der Neurologie und Psychiatrie. Wer sich fur den "state of the art" interessiert und TMS verstehen will, ist hier genau richtig - von der Routinediagnostik uber Befunde und den Einsatz in der Hirnforschung bis hin zu Therapie und Anwendung."

Anche se gli ultimi anni hanno visto uno sviluppo tumultuoso della ricerca oncologica, i tumori restano la causa di morte del 30% degli italiani.

Gli avanzamenti terapeutici facilitano la guarigione e prolungano la vita, ma proprio per questo rendono piu evidenti gli effetti indesiderati delle terapie e complicazioni delle neoplasie prima meno frequenti; in molti casi il danno da trattamento, piuttosto che quello dovuto alla neoplasia primitiva, diventa il principale azzardo per la qualita della vita e la sopravvivenza dei pazienti.

Questo volume, insieme necessario e nuovo nel panorama della letteratura medica italiana, ne prende atto e presenta una revisione aggiornata e completa delle patologie del sistema nervoso centrale e periferico associate ai tumori e al loro trattamento.

Scopo del volume e di presentare un approccio integrato tra specialisti che deve vedere il neurologo e l oncologo in dialogo, e in grado di sviluppare una nuova capacita clinica super-specialistica la neuro-oncologia .

Molti sono gli esperti che hanno contribuito alla sua preparazione mettendo in comune conoscenze su temi che variano dalle complicazioni metastatiche, a quelle della terapia chirurgica dei tumori, della radio- e chemio-terapia, alle sindromi paraneoplastiche, alla terapia del dolore, al delirium e alle alterazioni affettive associate alla malattia.

Il libro si rivolge in particolare a neurologi, oncologi, palliativisti e chirurghi, ma e certamente utile ai medici di medicina generale e a tutti gli operatori che sono quotidianamente coinvolti nell impegnativa opera di prendersi cura dei pazienti oncologici."

This practical guide for trainees and advanced practice providers covers the essential management of hospitalized patients with acute neurologic conditions. Divided into five sections, this text serves as an incredibly easy-to-use, visually accessible, how-to manual that covers exactly what every responding clinician needs to know to care for the patient in front of them. The first section provides tangible guidance about how to pre-round, structure a presentation, examine neurologically ill patients, and interpret the core diagnostics obtained in many neurology patients: CT, MRI and EEG. The next three sections cover common complaints encountered in the hospital: spanning from non-vascular admissions, vascular & stroke neurology topics, and core neurocritical care principals and chief complaints. Throughout are checklists, scoring systems, pro-tips, images, helpful reminders, as well as concise summary of the pertinent literature. This is an ideal guide for medical students, neurology & neurosurgery trainees and advanced practice providers, as well as experienced professionals who want to brush up on the latest updates.

The objective of this 5th edition of the book, as with the prior editions, is to teach through images a practical approach to magnetic resonance (MR) physics and image quality. Unlike other texts covering this topic, the focus is on clinical images rather than equations. A practical approach to MR physics is developed through images, emphasizing knowledge of fundamentals important to achieve high image quality. Pulse diagrams are also included, which many at first find difficult to understand. Readers are encouraged to glance at these as they go through the text. With time and repetition, as a reader progresses through the book, the value of these and the knowledge thus available will become evident (and the diagrams themselves easier to understand). The text is organized into concise chapters, each discussing an important point relevant to clinical MR and illustrated largely with images from routine patient exams. The topics covered encompass the breadth of the field, from imaging basics and pulse sequences to advanced topics including contrast-enhanced MR angiography, spectroscopy, perfusion and advanced parallel imaging/data sparsity techniques. Discussion of the latest hardware and software innovations, for example next generation low field MR, deep learning, MR-PET, 7 T, interventional MR, 4D flow, CAIPIRINHA, spiral techniques, radial acquisition, simultaneous multislice, compressed sensing and MR fingerprinting, is included because these topics are critical to current clinical practice as well as to future advances. Included in the fifth edition are a large number of new topics, keeping the text up to date in this increasingly complex field. The text has also been thoroughly revised to include additional relevant clinical images, to improve the clarity of descriptions, and to increase the depth of content. The book is highly recommended for radiologists, physicists, and technologists interested in the background of image acquisition used in standard as well as specialized clinical settings.

La sclerosi multipla (SM) rappresenta la seconda causa di disabilita neurologica nel giovane adulto, dopo i traumi cranici. Negli ultimi anni, l'introduzione di nuovi farmaci, potenzialmente in grado di modificare il decorso della malattia, ha richiamato l'attenzione sui costi sociali della SM e sugli aspetti farmaco-economici. Si sono avanzati, da un lato, timori che il costo dei nuovi farmaci costituisca un onere insostenibile per il sistema sanitario. Dall'altro lato, recenti studi economici hanno sottolineato l'importanza di una valutazione inserita in una prospettiva piu ampia, considerando la possibilita che le nuove terapie possano ridurre i costi sociali di malattia nel lungo termine, ritardando o evitando lo sviluppo di invalidita. Questo volume rivede la letteratura internazionale sui costi sociali della SM, e gli studi farmaco-economici sui nuovi farmaci per la malattia. In futuro, sara necessario implementare studi metodologicamente rigorosi, in particolare di tipo comparativo. Estremamente importante sara la raccolta di dati prospettici su ampie popolazioni di pazienti, per valutare il reale impatto delle nuove terapie sullo sviluppo di disabilita a lungo termine. Le informazioni attualmente disponibili derivano infatti essenzialmente dalle sperimentazioni terapeutiche, che si riferiscono a casistiche selezionate di pazienti seguiti per brevi periodi (2-3 anni). L'acquisizione di questi dati sara di importanza critica per migliorare la stima del rapporto costi/benefici con l'impiego dei nuovo farmaci e valutare le priorita in politica sanitaria negli anni a venire.

Die Navigation ist bei den komplexen Schadelbasisstrukturen zur Orientierung ausserst hilfreich und insbesondere bei knochernen Strukturen sehr prazise. In diesem Band werden Kosten, Nutzen, Vor- und Nachteile der Navigation, insbesondere in der Chirurgie der vorderen Schadelbasis und der Hypophysenregion, kritisch dargestellt. Weitere Beitrage setzen sich mit der chirurgischen Behandlung vaskularer Prozesse maligner Tumoren, Trumen und Fehlbildungen der vorderen Schadelgrube auseinander. Aus interdisziplinarer Sicht werden die Behandlung benigner Tumoren der Frontobasis, vornehmlich von Meningeomen, betrachtet. Sehr ubersichtlich werden auch die Behandlungsmoglichkeiten von Augenmuskelparesen dargestellt."

Innerhalb der Neuroorthopadie steht die Wirbelsaule im Mittelpunkt des Interesses. Der "Wandel in der Behandlung des Wirbelsaulenpatienten" war das Schwerpunktthema des Neuroorthopadiesymposiums der Friedrich-Alexander-Universitat Erlangen-Nurnberg und dem Klinikum Staffelstein. Die gravierenden medizinischen wie auch wirtschaftlichen Folgeerscheinungen von Ruckenschmerzen erfordern schon von Anfang an eine professionelle und konsequente Behandlungsstrategie um eine Schmerzchronifizierung zu vermeiden. Fortschritte auf dem Gebiet der medikamentosen, trainingstherapeutischen, interventionellen und psychotherapeutischen Behandlung erlauben erfolgversprechende interdisziplinare Behandlungsansatze."

Die Sektion 'Kindertraumatologie' der DGU - Deutsche Gesellschaft f r Unfallchirurgie - besch ftigte sich im Rahmen ihrer Jahrestagung mit dem wichtigen Thema "Das kindliche Polytrauma." Eine erfolgreiche Therapie des kindlichen Polytraumas wird entscheidend beeinflusst von einer engen interdisziplin ren Zusammenarbeit von Kinder- und Unfallchirurgen, An sthesisten, Kinder rzten, Neurochirurgen, Psychologen und Psychiatern. Die Beitr ge in dem Band tragen diesem Anspruch Rechnung.

Welche Lagerungen sind bei einem Patienten mit Hirndruck moeglich? Welche Formen der spinalen Stoerung gibt es? Welche Ursachen kann eine fehlerhafte Hirndruckmessung haben? Das Buch gibt klare Antworten zu allen Praxisfragen der neurologischen, neurochirurgischen und Intensivpflege, strukturiert nach dem Pflegemodell von Nancy Roper (ATL). Die 2. Auflage wurde komplett uberarbeitet und aktualisiert, z.B. diagnostische Methoden, Pflege bei Weaning und Beatmung, Dekubitiskalen, Massnahmen der Mundpflege.

A case-based guide to the interventional management of stroke from leading international experts! Stroke is the most prevalent cerebrovascular emergency, impacting an estimated 15 million people worldwide every year. Endovascular treatment (EVT) of ischemic stroke has expanded at an unforeseen pace, with EVT the most common neurointerventional procedure performed at most large centers. Endovascular Management of Ischemic Stroke: A Case-Based Approach by renowned stroke pioneer Vitor Mendes Pereira and distinguished co-editors features contributions from a "who's who" of global experts. This practical resource provides straightforward guidance for clinicians who need to learn and master state-of-the-art endovascular interventions reflecting the new, evidenced-based treatment paradigm for acute stroke. This carefully crafted reference takes readers on a journey from the early building blocks that led to modern stroke interventions to meticulous step-by-step descriptions of the latest approaches. Fifty high-yield cases mirror real-life scenarios trainees and professionals are likely to encounter in clinical practice. Seven sections encompass a full spectrum of diverse patient presentations, anatomical variations, advanced techniques, complex pathologies, complications, and stroke mimics. Key Highlights Discussion of emerging techniques likely to stand the test of time such as SAVE, ARTS, transradial access, and transcarotid access Stroke mimics important for differential diagnoses, including hemiplegic migraine, MELAS, RCVS, seizure, and more An appendix that covers fundamental terms, trials, and tools   This cutting-edge resource is essential reading for trainee and early-career interventionalists, as well as seasoned practitioners in interventional radiology, neuroradiology, endovascular neurosurgery, and interventional neurology. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Although a number of studies have addressed epilepsy from a va riety of qualitative and quantitative factors, relatively little systematic or multidisciplinary work has been reported to date. The general purpose of the present study was to analyze specific kinds of data from a large series of epileptic patients to focus the significance of the findings, particularly in relation to previously published results. Correlations among the following parameters are presented: age, sex, age at onset of seizure, type of seizure, paroxysmal electroencephalogram (EEG) abnormalities, basic EEG rhythm, family predisposition to epilepsy, and the presence of exogenous factors. The basic material of the present study consists of records of approximately 7400 patients treated at the outpatient clinic of the Department of Neurology, University of Heidelberg, in whom the clinical diagnosis suggested some type of epilepsy. Initially, the first consecutive 500 patients in an alphabetically arranged file were chosen for inclusion within the study if their clinical diagnosis was supplemented by at least one EEG examination. The final study group consisted of 466 patients, since 34 patients had to be excluded because of the lack of sufficient clinical information concerning them."

Neurodestruktive Methoden haben in der Behandlung chronischer Schmerzen - insbesondere nach der deutlichen Verbesserung der Durchfuhrungstechnik und der bildgebenden Kontrollverfahren - bei geeigneter Indikation einen grossen Stellenwert. Die Autoren stellen die wichtigsten Indikationsgebiete (z.B. Wirbelsaulenerkrankungen, Gesichtsschmerz, Tumorschmerz), die Zielpunkte und Verfahren sowie die Anatomie schmerzleitender Systeme klinisch dar und gehen auf Nebenwirkungen und Komplikationen dieser Methoden ein. Die Abbildungen verbessern das Verstandnis und helfen dem behandelnden Arzt bei der Umsetzung in die Praxis.
Die 2. Auflage wurde komplett uberarbeitet und Methoden erweitert: Neueste physiologische und pathopysiologische Grundlagen der Neurodestruktion, aktuelle Bildgebung in der perkutanen Schmerztherapie, gepulste Technik bei der Radiofrequenzlasion und Intradiskale Lasion (IDET)."

Das Buch enthalt die Beitrage ausgewiesener Experten zu drei der wesentlichen Hauptinnovationsfelder, die die Medizin im 21. Jahrhundert massgeblich bestimmen werden: 1. Biotechnologische Verfahren in Diagnostik und Therapie sowie 2. minimalinvasive, roboter- und EDV-gestutzte Operationstechniken und 3. mikrotherapeutische Eingriffe. Die Beitrage des Buches stellen in allgemeinverstandlicher Form den aktuellsten Wissens- und Entwicklungsstand der genannten Wissensgebiete dar und zeigen das diagnostische und therapeutische Spektrum auf. Jeder der Beitrage stellt fur sich die relevanten Verfahren, Modelle und Konzepte dar, verweist auf konkrete Forschungsergebnisse und skizziert das Innovationspotential der jeweils vertretenen Disziplin. Die Fachbeitrage folgen einer stringenten Gliederung und sind durch zahlreiche Abbildungen illustriert."

A high-yield and comprehensive text-and-video resource for managing commonly encountered spinal conditions Spine surgery has experienced several paradigm shifts during the past few decades, with highly complex techniques introduced at an astoundingly rapid pace. In order for new generations of spine surgeons to stay current and thrive in this innovative era of spine surgery, access to diverse multimedia learning tools is imperative. Video Atlas of Spine Surgery by renowned spine surgeon and educator Howard An and Rush University Medical Center colleagues Philip Louie, Bryce Basques, and Gregory Lopez, is a cutting-edge resource for non-operative and operative management of a diverse spectrum of cervical, thoracic, and lumbar spine conditions. Consisting of 19 chapters, the text is streamlined to facilitate learning the most important steps for each procedure. The book begins with discussion of physical exam maneuvers used to accurately diagnose specific spinal pathologies. Subsequent chapters detail extensive spine surgery techniques for managing degenerative cervical and lumbar conditions. The remaining chapters cover spinal cord, cervical, and thoracolumbar injuries; idiopathic, degenerative, and early-onset scoliosis; kyphosis; spondylolisthesis; spinal infections and inflammatory disorders; and thoracic disc disorders. Key Features Concise, bulleted text and consistent chapter outlines feature epidemiology and prevalence, pathogenesis, clinical presentation, image findings, classification, conservative and surgical management, techniques, postoperative care, and more A myriad of meticulous diagrams and illustrations, spinal imaging and photographs, and 50 high-quality spine surgery videos maximize learning Technical pearls, case examples, and board-style orthopaedic surgery questions at the end of each section optimize comprehension and retention of information This remarkable resource is a must-have for orthopaedic and neurosurgery residents and fellows, as well as practicing spine surgeons. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Die Epilepsien zahlen zu den haufigsten schwerwiegenden neurologischen Erkrankungen, deren Klinik, Diagnostik und Behandlung in den letzten Jahren durch die bessere Charakterisierung verschiedener Epilepsiesyndrome, die Verfeinerung von diagnostischen Verfahren und die Einfuhrung neuer Therapieoptionen einen betrachtlichen Wandel erfahren haben. Im vorliegenden Buch werden aktuelle Aspekte der Epidemiologie, der Prognose und des Verlaufs, der Ursachen (inklusive Genetik), der Diagnostik und Differentialdiagnostik, der Klinik (Anfallssemiologie und relevante Epilepsiesyndrome), der Therapie (medikamentose Therapie inklusive neue Antiepileptika, Epilepsiechirurgie, alternative Therapien inklusive ketogene Diat) und der psychosozialen Aspekte der Epilepsien dargestellt. Besonderer Wert wurde dabei auf eine praxisorientierte Darstellung gelegt. Dieses Buch bietet eine Entscheidungsgrundlage im klinischen Alltag und hilft, die diagnostischen und therapeutischen Massnahmen auf eine rationale, dem aktuellsten Wissensstand entsprechende Basis zu stellen."

Neben der Darstellung Atiopathogenetischer Hypothesen des Torticollis spasmodicus aus neuro-orthopAdischer Sicht werden die Ergebnisse einer eigenen innovativen Methode zur klinischen und elektrophysiologischen Untersuchung von Torticollispatienten in A1/4bersichtlicher Form vorgestellt. Die differenzierte Diagnostik mit semiquantitativer EMG-Auswertung ist eine unverzichtbare Entscheidungshilfe bei Indikation und Auswahl der effektivsten Operation. Diese ist besonders fA1/4r den Neurochirurgen von Interesse.